1,081
Views
10
CrossRef citations to date
0
Altmetric
Original Article

Activated FVII levels in factor VII Padua (Arg304Gln) coagulation disorder and in true factor VII deficiency: a study in homozygotes and heterozygotes

, , , &
Pages 308-312 | Published online: 12 Nov 2013

References

  • Morrissey JH, Mutch NJ. Tissue factor structure and function. In: , Colman R W, Marder V J, Clowes A W, George J N, Goldhaber S Z, editors. Hemostasis, thrombosis. 5th, ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2006. p. 91–106.
  • Rao LV, Robinson T, Hoang AD. Factor VIIa/tissue factor-catalyzed activation of factors IX and X on a cell surface and in suspension: a kinetic study. Thromb Haemost 1992;67:654–9.
  • Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood 1993;81:734–44.
  • Morrissey JH. Plasma factor VIIa: measurement and potential clinical significance. Haemostasis 1996;26(Suppl. 1):66–71.
  • Hellstern P, Beeck H, Fellhauer A, Fischer A, Faller-Stöckl B. Measurement of factor VII and of activated factor VII in healthy individuals and in prothrombin complex concentrates. Thromb Res 1997;86:493–504.
  • Lippi G, Montagnana M, Salvagno GL, Poli G, Franchini M, Guidi GC. Influence of warfarin therapy on activated factor VII clotting activity. Blood Coagul Fibrinolysis 2006;17:221–4.
  • Yamada A, Wada H, Kamikura Y, Hiyoyama K, Shimura M, Nagaya S, et al.. Plasma levels of activated FVII in various diseases. Blood Coagul Fibrinolysis 1996;7:794–8.
  • Bourgeat P, Jasmin P, Migaud-Fressart M, Martinoli JL. Direct measurement of activated factor VII in plasma: development of an original assay. Thromb Haemostas 1995;73:1204.
  • Perry DJ. Factor VII deficiency. Br J Haematol 2002;118:689–700.
  • Girolami A, Fabris F, Dal Bo Zanon R, Ghiotto G, Burul A. Factor VII Padua: a congenital coagulation disorder due to an abnormal factor VII with a peculiar activation pattern. J Lab Clin Med 1978;91:387–95.
  • Girolami A, Sartori MT, Steffan A, Fadin MA. Recombinant thromboplastin is slightly more sensitive to factor VII Padua than standard thromboplastins of human origin. Blood Coagul Fibrinolysis 1993;4:497–8.
  • Girolami A, Patrassi G, Cappellato G, Casonato A. Another family with the factor VII Padua clotting defect. Acta Haematol 1979;62:4–11.
  • Girolami A, Dal Bo Zanon R, Zanella F, Procidano M, Ruffato G. Factor VII Padua defect: the heterozygote population. Acta Haematol 1982;68:34–8.
  • Girolami A, de Marinis GB, Bonamigo E, Allemand E. Worldwide diffusion of FVII Arg304Gln in coagulation defect (FVII Padua). Eur J Haematol 2011;86:135–9.
  • Saito M, Asakura H, Yoshida T, Jokaji H, Uotani C, Kumabashiri I, et al.. Levels of activated factor VII in patients with disseminated intravascular coagulation. Blood 1995;85:3770–1.
  • Meade TW, Ruddock V, Stirling Y, Chakrabarti R, Miller GJ. Fibrinolytic activity, clotting factors, and long-term incidence of ischaemic heart disease in the Northwick Park Heart Study. Lancet 1993;342:1076–9.
  • Miller GJ, Walter SJ, Stirling Y, Thompson SG, Esnouf MP, Meade TW. Assay of factor VII activity by two techniques: evidence for increased conversion of VII to alpha VIIa in hyperlipidaemia, with possible implications for ischaemic heart disease. Br J Haematol 1985;59:249–58.
  • Cid AR, Lorenzo JI, Haya S, Montoro JM, Casaña P, Aznar JA. A comparison of FVII:C and FVIIa assays for the monitoring of recombinant factor VIIa treatment. Haemophilia 2001;7:39–41.
  • Croom KF, McCormack PL. Recombinant factor VIIa (eptacog alfa): a review of its use in congenital hemophilia with inhibitors, acquired hemophilia, and other congenital bleeding disorders. BioDrugs 2008;22:121–36.
  • Klitgaard T, Nielsen TG. Overview of the human pharmacokinetics of recombinant activated factor VII. Br J Clin Pharmacol 2008;65:3–11.
  • Scarabin PY, Vissac AM, Kirzin JM, Bourgeat P, Amiral J, Agher R, et al.. Population correlates of coagulation factor VII. Importance of age, sex, and menopausal status as determinants of activated factor VII. Arterioscler Thromb Vasc Biol 1996;16:1170–6.
  • Scharling B, Nielsen GG, Klitgaard T, Skovsted TA, Møss J, Segel S, et al.. Comparison of coagulant activity of factor VII and activated factor VII activity assays when used for determination of recombinant activated factor VII levels in plasma. Blood Coagul Fibrinolysis 2007;18:677–84.
  • Kario K, Matsuo T, Asada R, Sakata T, Kato H, Miyata T. The strong positive correlation between factor VII clotting activity using bovine thromboplastin and the activated factor VII level. Thromb Haemost 1995;73:429–34.
  • Kitchen S, Malia RG, Preston FE. A comparison of methods for the measurement of activated factor VII. Thromb Haemost 1992;68:301–5.
  • Shurafa MS, Kumar A, Fair DS, James HL. The molecular defect in FVII (Detroit) is due to substitution of Arg(304) by Glu. FASEB J 1993;17:115 (abstract).
  • Sabharwal AK, Kuppuswamy MN, Foster DC, Wildgoose P, Fisher L, Birktoft JJ, et al.. Factor VII deficiency (F VII Richmond, R304Q mutant) associated with thrombosis. Circulation 1992;86(Suppl.):679 (abstract).
  • Etro D, Pinotti M, Wulff K, Marchetti G, Rocino A, Herrmann FH, et al.. The Gly331Ser mutation in factor VII in Europe and the Middle East. Haematologica 2003;88:1434–6.
  • Wulff K, Herrmann FH. Twenty two novel mutations of the factor VII gene in factor VII deficiency. Hum Mutat 2000;15:489–96.
  • Marty S, Barro C, Chatelain B, Fimbel B, Tribout B, Reynaud J, et al.. The paradoxical association between inherited factor VII deficiency and venous thrombosis. Haemophilia 2008;14:564–70.
  • Triplett DA, Brandt JT, Batard MA, Dixon JL, Fair DS. Hereditary factor VII deficiency: heterogeneity defined by combined functional and immunochemical analysis. Blood 1985;66:1284–7.
  • Girolami A, Tezza F, Scandellari R, Vettore S, Girolami B. Associated prothrombotic conditions are probably responsible for the occurrence of thrombosis in almost all patients with congenital FVII deficiency. Critical review of the literature. J Thromb Thrombolysis 2010;30:172–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.