Publication Cover
Redox Report
Communications in Free Radical Research
Volume 6, 2001 - Issue 4
66
Views
1
CrossRef citations to date
0
Altmetric
Research Articles

An improved method for the sensitive monitoring of low density lipoprotein modification by myeloperoxidase

, , &
Pages 257-264 | Published online: 19 Jul 2013

  • Heinecke JW. Mechanism of oxidative damage of low density lipoprotein in human atherosclerosis. Curr Opin Lipidol 1997; 8: 268–274.
  • Jerlich A, Fabjan JS, Tschabuschnig S et al. Human low density lipoprotein as a target of hypochlorite generated by myeloperoxidase. Free Radic Biol Med 1998,24: 1139–1148.
  • Jerlich A, Pitt AR, Schaur RJ et al. Pathways of phospholipid oxidation by HOC1 in human LDL detected by LC-MS. Free Radic Biol Med 2000; 28: 673–682.
  • Hazell LJ, Van den Berg JJM, Stocker R. Oxidation of low density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation. Biochem J 1994; 302: 297–304.
  • Jerlich A, Fritz G, Itharrazi H et al. Comparison of HOC1 traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation. Biochim Biophys Acta 2000; 1481: 109–118.
  • Jerlich A, Hammel M, Nigon F et al. Kinetics of tryptophan oxidation in plasma lipoproteins by myeloperoxidase-generated HOC1. Eur J Biochem 2000; 267: 4137–4143.
  • Leff JA, Repine JE. Neutrophil-mediated tissue injury. In: Abramson JS, Wheeler JG. (eds) The Neutrophil, Oxford: IRL, 1993; 229-262.
  • Daugherty A, Rateri DL, Dunn JL et al. Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions. J Clin Invest 1994; 94: 437–444.
  • Hazell LJ, Stocker R. Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages. Biochem J 1993; 290: 165–172.
  • Lakovicz JR. Principles of Fluorescence Spectroscopy. New York: Plenum, 1983.
  • Gießauf A, Steiner E, Esterbauer H. Early destruction of tryptophan residues of apolipoprotein B is a vitamin E-independent process during copper-mediated oxidation of LDL. Biochim Biophys Acta 1995; 1256: 221–232.
  • Jerlich A, Horakova L, Fabjan JS et al. Correlation of low density lipoprotein modification by myeloperoxidase with hypochlorous acid formation. Int J Clin Lab Res 1999; 29: 155–161.
  • Esterbauer H, Ramos P. Chemistry and pathophysiology of oxidation of LDL. Rev Physiol Biochem Pharmacol 1995; 127: 31–63.
  • Harper HA, Loftier G, Petrides PE et al. Physiologische Chemie. Berlin: Springer, 1995.
  • Tobler A, Koffler HP. Myeloperoxidase: localization, structure, and function. In: Harris JR. (ed) Blood Cell Biochemistry, Vol. 3 Lymphocytes and Granulocytes. New York: Plenum, 1991; 255-288.
  • Kleinveld HA, Hak-Lemmers HLM, Stalenhoef AFH et al. Improved measurement of low-density-lipoprotein susceptibility to copper-induced oxidation: application of a short procedure for isolating low-density-lipoprotein. Clin Chem 1992; 38: 2066–2072.
  • Ramos P, Gieseg SP, Schuster B et al. Effect of temperature and phase-transition on oxidation resistance of low-density-lipoprotein. J Lipid Res 1995; 36: 2113–2129.
  • Dobretsov GE, Spirin MM, Chelcrygin OV et al. A fluorescence study of apolipoprotein localization in relation to lipids in serum low density lipoproteins. Biochim Biophys Acta 1982; 710: 172–180.
  • Panasenko OM, Arnhold J. Linoleic acid hydroperoxide favours hypochlorite- and myeloperoxidase-induced lipid peroxidation. Free Radic Res 1999; 30: 479–487.
  • Roessner A, Vollmer E, Jaeger E et al. Differentiation and role of macrophages in the early human atherosclerotic plaque. In: Vollmer E, Roessner A. (eds) Recent Progress in Atherosclerosis Research. Berlin: Springer, 1993; 59-71.
  • Prescott MF, McBride CK, Court M. Development of intimal lesions after leukocyte migration into the vascular wall. Am J Pathol 1989; 135: 835–846.
  • Kling D, Holzschuh T, Betz E. Recruitment and dynamics of leukocytes in the formation of arterial Ultima' thickening - a comparative study with normo- and hypercholesterolemic rabbits. Atherosclerosis 1993; 101: 79–96.
  • Völker W, Dorszewski A, Unruh V et al. Copper-induced inflammatory reactions of rat carotid arteries mimic restenosis/arteriosclerosis-like neointima formation. Atherosclerosis 1997; 130: 29–36.
  • Klebanoff SJ. Myeloperoxidase: occurrence and biological function. In: Everse J, Everse KE, Grisham MB. (eds) Peroxidases in Chemistry and Biology, Vol. 1. Boca Raton: CRC Press, 1991; 1-36.
  • Winterbourn CC, Garcia R, Segal AW. Production of the superoxide adduct of myeloperoxidase (compound HI) by stimulated neutrophils, and its reactivity with 11202 and chloride. Biochem J 1985; 228: 583–592.
  • Weening RS, Roos D, Loos JA. Oxygen consumption of phagocytizing cells in human leukocyte and granulocyte preparations: a comparative study. J Lab Clin Med 1974; 83: 570–577.
  • Martin 2nd WJ. Neutrophils kill pulmonary endothelial cells by a hydrogen-peroxide-dependent pathway. An in vitro model of neutrophil-mediated lung injury. Am Rev Respir Dis 1984; 130: 209–213.
  • Leake DS. Does an acidic pll explain why low density lipoprotein is oxidised in atherosclerotic lesions? Atherosclerosis 1997; 129: 149–157.
  • Suzuki M, Mon M, Miura S et al. Omeprazole attenuates oxygen-derived free radical production from human neutrophils. Free Radic Biol Med 1996; 21: 727–731.
  • Sepe SM, Clark RA. Oxidant membrane injury by the neutrophil myeloperoxidase system. I. Characterization of a liposome model and injury by myeloperoxidase. J Immunol 1985; 134: 1888–1895.
  • Sepe SM, Clark RA. Oxidant membrane injury by the neutrophil myeloperoxidase system. II Injury by stimulated neutrophils and protection by lipid-soluble antioxidants, J Immunol 1985; 134: 1896-1901.
  • Hazen SL, Heinecke JW. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic J Clin Invest 1996; 99: 2075-2081.
  • Kettle AJ, Winterbourn CC. Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode. Biochem J 1989; 263: 823–828.
  • Hazell LI, Arnold L, Flowers D et al. Presence of hypochlorite-modified proteins in human atherosclerotic lesions. J Clin Invest 1996; 97: 1535–1544.
  • Laggner P, Glatter 0, Muller KW et al. The lipid bilayer structure of the abnormal human plasma lipoprotein X. An X-ray small-angle-scattering study. Eur J Biochem 1977; 77: 165–171.
  • O'Connell A, Gieseg SP, Stanley MC. Hypochlorite oxidation causes cross-linking of Lp (a). Biochim Biophys Acta 1994; 1225: 180–186.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.