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Redox Report
Communications in Free Radical Research
Volume 6, 2001 - Issue 4
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Intracellular superoxide and hydrogen peroxide concentrations: a critical balance that determines survival or death

M-V. ClémentOncology Research Institute National University Medical Institutes , Singapore
&
S. PervaizDepartment of Physiology National University of Singapore , Singapore
Pages 211-214 | Published online: 19 Jul 2013

  • Bunke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994; 15: 7–10.
  • Brunk UT, Svensson I. Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak. Redox Rep 1999; 4: 3–11.
  • Hirpara JL, Clement M-V, Pervaiz S. Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells. J Biol Chem 2001; 276: 514–521.
  • Burdon R. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18: 775–794.
  • Chaudhri G, Hunt NH, Clark IA, Ceredig R. Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myrstate acetate and ionomycin. Cell Immunol 1988; 115: 204–213.
  • Clément M-V, Stamenkovic I. Superoxide anion is a natural inhibitor of Fas-mediated cell death. EMBO J 1996; 15: 216–225.
  • Shacter E, Williams JA, Hinson RM, Senturker S, Lee YJ. Oxidative stress interferes with cancer chemotherapy: inhibition of lymphoma cell apoptosis and phagocytosis. Blood 2000; 96: 307–313.
  • Cerutti PA. Prooxidant states and tumor promotion. Science 1985; 227: 375–381.
  • Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. Oxford: Clarendon Press, 1999.
  • Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-KB transcription factor and HIV-1. EMBO J1991; 10: 2247-2258.
  • Clément M-V, Ponton A, Pervaiz S. Apoptosis induced by hydrogen peroxide is mediated by a decreased superoxide anion concentration and reduction of intracellular milieu. FEBS Lett 1998; 440: 13–18.
  • Fiers W, Beyaert R, Declercq W, Vandenabeele P. More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 1999; 18: 7719–7730.
  • Wyllie All, Ken JF, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251–256.
  • Slee EA, Adrain C, Martin SJ. Serial killers: ordering caspase activ-ation events in apoptosis. Cell Death Differ 1999; 6: 1067–1074.
  • Desagher S, Martinou JC. Mitochondria as the central control point of apoptosis. Trends Cell Biol 2000; 10: 369–377.
  • Majno G, Joris I. Apoptosis, oncosis and necrosis, an overview of cell death. Am J Pathol 1995; 146: 3–19.
  • Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H, Tsujimoto Y. Prevention of hypoxia-induced cell death by Bd-2 and Bd-xL. Nature 1995; 374: 811–813.
  • Halliwell B, Gutteridge JM. Role of free radicals and catalytic metal ions in human disease: an overview. Methods Enzymol 1990; 186: 1–85.
  • Pervaiz S, Ramalingam JK, Hirpara JL, Clement M-V. Superoxide anion inhibits drug-induced tumor cell death. FEBS Lett 1999; 459: 343–348.
  • Pervaiz S. Reactive oxygen-dependent production of novel photochemotherapeutic agents. FASEB J 2001; 15: 612–617.
  • Matsuyama S, Reed JC. Mitochondria-dependent apoptosis and cellular pH regulation. Cell Death Differ 2000; 7: 1155–1165.
  • Shibanuma M, Kuroki T, Nose K. Superoxide as a signal for increase in intracellular pH. J Cell Physiol 1988; 136: 379–383.
  • Kaufman DS, Goligorsky MS, Nord EP, Graber ML. Perturbation of cell pH regulation by 11202 in renal epithelial cells. Arch Biochem Biophys 1993; 302: 245–254.
  • Hu Q, Xia Y, Corda S, Zweier JL, Ziegelstein RC. Hydrogen peroxide decreases 011 in human aortic endothelial cells by inhibiting Neill exchange. Circ Res 1998; 83: 644–651.
  • Schraufstatter IU, Hyslop PA, Hinshaw DB, Spragg RG, Sklar LA, Cochrane CG. Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase. Proc Natl Acad Sci USA 1986; 83: 4908–4912.
  • Van Driel BE, Lyon II, Hoogenraad DC, Anten S, Hansen U, Van Noorden CJ. Expression of CuZn- and Mn-superoxide dismutase in human colorectal neoplasms. Free Radic Biol Med 1997; 23: 435–444.

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