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Redox Report
Communications in Free Radical Research
Volume 7, 2002 - Issue 1
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Research Articles

Free radical scavenging activity of vanillin and o-vanillin using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical

S. Santosh KumarCell Biology Division Bhabha Atomic Research Centre, Modular Laboratories, Trombay, Mumbai, India
,
K. I. PriyadarsiniRadiation Chemistry and Chemical Dynamics Division Bhabha Atomic Research Centre, Modular Laboratories, Trombay, Mumbai, India
&
K. B. SainisCell Biology Division Bhabha Atomic Research Centre, Modular Laboratories, Trombay, Mumbai, India
Pages 35-40 | Published online: 19 Jul 2013

  • Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants and the degenerative diseases of ageing. Proc Natl Acad Sci USA 1993;90: 7915–7922.
  • Sies H. Antioxidants in Disease: Mechanisms and Therapy. New York: Academic Press, 1997.
  • Bonnefont RD, Bastard JP, Jandon MC, Delattre J. Consequences of the diabetic status on oxidant/antioxidant balance. Diabetes Metab 2000; 26: 163–176.
  • Thomas CE, Kalyanaraman B. (eds) Oxygen Radicals and the Disease Process. Chur: Harwood Academic, 1998.
  • Hall EJ, Kereiakes JG. Effects of ionizing radiation on cells. In: Sperelakis N. (ed) Cell Physiology Source Book, 2nd edn. New York: Academic Press, 1998; 1044-1060.
  • Lampe JW. Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies. Am J Clin Nutr 1999; 70: 475S-490S.
  • Noguchi N, Niki E. Phenolic antioxidants: a rationale for design and evaluation of novel antioxidant drug for atherosclerosis. Free Radic Biol Med 2000; 28: 1538–1546.
  • Kong Q, Beel JA, Lillehei KO. A threshold concept for cancer therapy. Med Hypotheses 2000; 55: 29–35.
  • Prince RC, Gun son DE. Just plain vanilla? Trends Biochem Sci 1994; 19: 521.
  • Vanillin RHOVANIL, Monograph RP 10/95, France: Rhone-Poulenc Chimie, 1995.
  • Ohta T. Modification of genotoxicity by naturally occurring flavorings and their derivatives. Crit Rev Toxicol 1993; 23: 127–146.
  • Tamai K, Tezuka H, Kuroda Y. Different modifications by vanillin in cytotoxicity and genetic changes induced by EMS and H202 in cultured Chinese hamster cells. Mutat Res 1992; 268: 231–237.
  • Keshava C, Keshava N, Ong T, Nath J. Protective effect of vanillin on radiation-induced micronuclei and chromosomal aberrations in V79 cells. Mutat Res 1998; 397: 149–159.
  • Tsuda H, Uehara N, Iwahori Y et al. Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo sbd (4,5-0-quinoline in the rat. Jpn J Cancer Res 1994; 85: 1214–1219.
  • Santosh Kumar S, Arna Ghosh Devasagayam TPA, Chauhan PS. Effect of vanillin on methylene blue plus light-induced single-strand breaks in plasmid pBR322 DNA. Mutat Res 2000; 469: 207–214.
  • Kamat JP, Ghosh A, Devasagayam TPA. Vanillin as an antioxidant in rat liver mitochondria: inhibition of protein oxidation and lipid peroxidation induced by photosensitization. Mol Cell Biochem 2000; 209: 47–53.
  • Matsumura H, Watanabe K, Ohta T. o-Vanillin enhances chromosome aberrations induced by alkylating agents in cultured Chinese hamster cells. Mutat Res 1993; 298: 163–168.
  • Watanabe K, Ohta T. Mutation enhancing effect of o-vanillin in the lacZ gene of Escherichia coli: characterization of mutational spectrum. Mutat Res 1993; 302: 13–18.
  • Takahashi K, Sekiguchi M, Kawazoe Y. A specific inhibition of induction of adaptive response by o-vanillin, a potent comutagen. Biochem Biophys Res Commun 1989; 162: 1376–1381.
  • Santiago LA, Osato JA, Hiramatsu M, Edamatsu R, Mori A. Free radical scavenging action of biocatalyzer alpha.rho No. 11 (Bio-normalizer) and its by-product. Free Radic Biol Med 1999; 11: 379–383.
  • Wang M, Jin Y, Ho CT. Evaluation of resveratrol derivatives as potential antioxidants and identification of a reaction product of resveratrol and 2,2-dipheny1-1-picrylhydiazyl radical. J Agric Food Chem 1999; 47: 3974–3977.
  • Yamaguchi T, Takamura H, Matoba T, Terao J. HPLC method for evaluation of the free radical scavenging activity of foods by using 1,1-dipheny1-2-picrylhydrazyl.Biosci Biotechnol Biochem 1998;62: 1201–1204.
  • Buettner GR. The pecking order of free radicals and antioxidants, lipid peroxidation, a-tocopherol, and ascorbate. Arch Biochem Biophys 1993;300: 535–543.
  • Davies MJ, Forni LG, Wilson RL. Vitamin E analogue trolox C: ESR and pulse radiolysis studies of free radical reactions. Biochem J 1988; 255: 513–518.

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