REFERENCES
- Comporti M. Lipid peroxidation and cellular damage in toxic liver injury. Lab Invest 1985; 53: 599–623.
- Recknagel RO, Glende EA, Dolak JA, Waller RL. Mechanisms of carbon tetrachloride toxicity. Pharmacol Ther 1989; 43: 139–154.
- Brent AJ, Rumack BH. Role of free radicals in toxic hepatic injury. Are the free radicals the cause of toxin-induced liver injury?. Clin Toxicol 1993; 31: 173–196.
- HarborneJ B. The Flavonoids: Advances in Research since 1986. London: Chapman and Hall, 1993.
- HarborneJ B. Methods in Plant Biochemistry, I: Plant Phenolics. London: Academic Press, 1989.
- Haslam E. Vegetable Tannins. London: Academic Press, 1966.
- Scalbert A. Polyphenolic Phenomena. Paris: INRA, 1993.
- Pietta PG. Flavonoids as antioxidant. J Nat Prod 2000; 63: 1035–1042.
- Formica JV, Regel son W. Review of the biology of quercetin and related bioflavonoids. Food Chem Toxicol 1995; 33: 1061–1080.
- Russo A, Acquaviva R, Campisi A et al. Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors. Cell Biol Toxicol 2000; 16: 91–98.
- Hirono I. Naturally ocurring carcinogens of plant origin. Toxicology, phytology and biochemistry. Biol Pharm Bull 1987; 2: 120–158.
- Korkina LG, Afanas'evIB. Antioxidant and chelating properties of flavonoids. In: Sies H. (ed) Advances in Pharmacology. San Diego: Academic Press, 1997; 151–163.
- Manach C, Regerat F, Texier O, Agullo G, Demigne C, Remesy C. Bioavailability, metabolism and physiological impact of 4-oxo-flavonoids. Nutr Res 1996; 16: 517–544.
- Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 1983; 32: 1141–1148.
- Morazzoni P. Bombardelli E. Sylibum marianum (Carduus marianus). Fitoterapia 1995; 66: 3–42.
- Pietrangelo A, Borella F, Casalgrandi G et al. Antioxidant activity of sylibin in vivo during long-term iron overload in rats. Gastroenterology 1995; 109: 1941–1949.
- Brandi ML. Flavonoids: biochemical effects and therapeutic applications. Bone Mineral 1992; 19: s3–s14.
- van Acker SAVE, van den Berg DJ, Tromp MNJL et al. Structural aspects of antioxidant activity of flavonoids. Free Radic Biol Med 1996; 20: 331–342.
- De Groot H, Rauen U. Tissue injury by reactive oxygen species and the protective effects of flavonoids. Fundam Clin Pharmacol 1998; 12: 249–255.
- Trueba G, Marti nez B, Ma rquez I, Ramos C. Evaluació n de la actividad antioxidante de la gossypitrina a travd s de ensayosin vitroe in vivo. Rev Mex Cienc Farm 2001; 32: 18–21.
- Farnsworth RN. Agentes Hepatoprotectores. I Simposio Latinoamericano y del Caribe de los Fá rmacos Naturales. Personal communication 1980.
- Boehringer Mannheim. Biochemical information. A revised biochemical reference sources. In: Enzymes for Routine, 1st edn. Mannheim: Boehringer Mannheim, 1987; 80-81.
- Boehringer Mannheim. Biochemical information. A revised biochemical reference sources. In: Enzymes for Routine, 1st edn. Mannheim: Boehringer Mannheim, 1987; 15-16.
- Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302–310.
- Bradford MM. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976; 72: 248–254.
- Muriel P. Garciapina T, Perez-Alvarez V. Mourelle M. Sylimarin protects against paracetamol-induced lipid peroxidation and liver damage. J Appl Toxicol 1992; 12: 439–442.
- Wu C-G, Chamuleau RAFM, Bosch KS, Frederiks WM. Protective effects of sylimarin on rat liver injury induced by ischemia. Virchows Arch B Cell Pathol 1993; 64: 259–263.
- van Acker Frdd rique AA, Schouten O, Guido RMM, Haenen WJF, van der Vijgh, Bast A. Flavonoids can replace a-tocopherol as an antioxidant. FEBS Lett 2000; 473: 145–148.
- Ratty AK, Das NP. Effects of flavonoids on non-enzymatic lipid peroxidation: structure-activity relationship. Biochem Med Metab Biol 1998; 39: 69–79.
- KochH P, Loffler E. Influence of silymarin and some flavonoids on lipid peroxidation in human platelets. Methods Find Exp Clin Pharmacol 1985; 7: 13–18.
- Saija A, Scalese M, Lanza M, Marzullo D, Bonina F, Castelli F. Flavonoids as antioxidant agents: importance of their interaction with biomembranes. Free Radic Biol Med 1995; 19: 481–486.
- Morata P. ColmeneroJD, Sá nchez-CarrilloJJ, Morell M. Serum activity of the key gluconeogenic enzymes in carbon tetrachloride-induced experimental hepatotoxicity. Enzyme 1990; 43: 169–174.
- Clarke H, Egan DA, Hefernan M et al. a-Glutathione 5-transferase release, an early indicator of carbon tetrachloride hepatotoxicity in the rat. Hum Exp Toxicol 1997; 16: 154–157.
- Favari L, P rez-Alvarez V. Comparative effects of colchicine and silymarin on CC14-chronic liver damage in rats. Arch Med Res 1997; 28: 11–17.
- Karan M, Vasisht K, Handa SS. Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats. Phytother Res 1999; 13: 24–30.
- Candelario E, Mohammed S, Leo n OS, Mend ndez S, P rez G. Oxidative preconditioning affords protection against carbon tetrachloride-induced glycogen depletion and oxidative stress in rats. J Appl Toxicol 2001; 21: 297–301.
- Vaca CE, Vodicka P. Hemminki K. Determination of malonaldehyde-modified 2'-deoxyguanosine-3'-monophosphate and DNA by [3211-postlabelling. Carcinogenesis 1992; 13: 593–599.
- Cambiaggi C, Dominici S, Comporti M, Pompella A. Modulation of human T lymphocyte proliferation by 4-hydroxynonenal, the bioactive product of neutrophil-dependent lipid peroxidation. Life Sci 1997; 61: 777–785.
- Parasassi T, Martelucci I, Conti F, Messina B. Drug-membrane interactions: silymarin, silybin and microsomal membranes. Cell Biochem Funct 1984; 2: 85–88.
- B ors W, Michel C, Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. Methods Enzymol 1990; 186: 343–355.
- Arora A, Nair MG. Structure-activity relationships for antioxidants activities of a series of flavonoids in a liposomal system. Free Radic Biol Med 1998; 24: 1355–1363.
- Cholbi MR, Paya M, Alcaraz MJ. Inhibitory effects of phenolic compounds on CC14-induced microsomal lipid peroxidation. Experientia 1991; 47: 195–199.