Oxygen-sensing pathways and the development of mammalian gas exchange

REFERENCES

• Lopez-Barneo J, Pardal R, Ortega-Saenz P. Cellular mechanism of oxygen sensing. Annu Rev Physiol 2001; 63: 259–287.
   PubMed Web of Science ®Google Scholar
• Hochachka PW, Buck LT, Doll CJ, Land SC. Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci USA 1996; 93: 9493–9498.
   PubMed Web of Science ®Google Scholar
• Fischer B, Bavister BD. Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits. J Reprod Fertil 1993; 99: 673–679.
   PubMedGoogle Scholar
• Bert P. Legons sur la physiologie comparée de la respiration. Paris: Balifere, 1870.
   Google Scholar
• Bohr C. Der respiratorishe Stoffwechsel des saugethierembryos Skand Arch Physiol 1900; 10: 413–424.
   Google Scholar
• Hill JR, Rahimtulla KA. Heat balance and the metabolic rate of new-born babies in relation to environmental temperature; and the effect of age and of weight on basal metabolic rate. J Physiol 1965; 180: 239–265.
   PubMedGoogle Scholar
• Hasselbalch, AK. Uber den respiratorishen Stoffwechsel des huhnerembryos. Skand Arch Physiol 1900; 10: 353–402.
   Google Scholar
• Bell AW, Battaglia FC, Meschia G. Relation between metabolic rate and body size in the ovine fetus. J Nutr 1987; 117: 1181–1186
   PubMed Web of Science ®Google Scholar
• Fazekas JF, Alexander FAD, Himwish HE. Tolerance of the newborn to anoxia. Am J Physiol 1941; 134: 281–287.
   Google Scholar
• Kleiber M. Body and size and metabolism. Hilgardia 1932; 6: 315–353.
   Google Scholar
• Schroder HJ, Power GG. Engine and radiator: fetal and placental interactions for heat dissipation. Exp Physiol 1997; 82: 403–414.
   PubMed Web of Science ®Google Scholar
• Edelstone DI, Peticca BB, Goldblum U. Effects of maternal oxygen administration on fetal oxygenation during reductions in umbilical blood flow in fetal lambs. Am J Obstet Gynecol 1985; 152: 351–358.
   PubMed Web of Science ®Google Scholar
• Itskovitz J, LaGamma EF, Rudolph AM. The effect of reducing umbilical blood flow on fetal oxygenation. Am J Obstet Gynecol 1983; 145: 813–818.
   PubMed Web of Science ®Google Scholar
• Hochachka PW. Oxygen, homeostasis, and metabolic regulation. Adv Exp Med Biol 2000; 475: 311–335.
   PubMed Web of Science ®Google Scholar
• Tian H, McKnight SL, Russel DW. Endothelial PAS domain protein-1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 1997; 11: 72–82.
   PubMed Web of Science ®Google Scholar
• Wiesener MS, Turley H, Allen WE et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-la. Blood 1998; 92: 2260–2268.
   PubMed Web of Science ®Google Scholar
• Makino Y, Cao R, Svensson K et al. Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression. Nature 2001; 414: 550–554.
   PubMed Web of Science ®Google Scholar
• Epstein AC, Gleadle JM, McNeill LA et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulateHIF by prolyl hydroxylation. Cell 2001; 107: 43–54.
   PubMed Web of Science ®Google Scholar
• Bruick RK, McKnight SL. Conserved family of proly1-4-hydroxylases that modifyHIF. Science 2001; 294: 1337–1340.
   PubMed Web of Science ®Google Scholar
• Hewitson KS, McNeill LA, Riordan MV et al. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibitingHIF (FIH) and is related to the cupin structural family. J Biol Chem 2002; 277: 26351–26355.
   PubMed Web of Science ®Google Scholar
• Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML. Asparagine hydroxylation of theHIF transactivation domain: a hypoxic switch. Science 2002; 295: 858–861.
   PubMed Web of Science ®Google Scholar
• Acker HE, Dufau Huber J, Sylvester D. Indications to an NADPH oxidase as a possible P02 sensor in the rat carotid body. FEBS Lett 1989; 256: 75–78.
   PubMed Web of Science ®Google Scholar
• Fandrey J, Frede S, Jelkmann W. Role of hydrogen peroxide in hypoxia-induced erythropoietin production. Biochem J 1994; 303: 507–510.
   PubMed Web of Science ®Google Scholar
• Gorlach A, Fandrey J, Holtermann G, Acker H. Effects of cobalt on haem proteins of erythropoietin-producing HepG2 cells in multicellular spheroid culture. FEBS Lett 1994; 348: 216–218.
   PubMed Web of Science ®Google Scholar
• Wang D, Youngson C, Wong V et al. NADPH oxidase and a hydrogen peroxide sensitive KC channel may function as an oxygen sensor complex in airway chemoreceptors and small cell lung carcinoma cell lines. Proc Natl Acad Sci USA 1996; 93: 13182–13187.
   PubMed Web of Science ®Google Scholar
• O'Kelly I, Lewis A, Peers C, Kemp PJ.O2 sensing by airway chemoreceptor-derived cells. Protein kinase C activation reveals functional evidence for involvement of NADPH oxidase. J Biol Chem 2000; 275: 7684–7692.
   PubMed Web of Science ®Google Scholar
• Fu XW, Wang D, Nurse CA, Dinauer MC, Cutz E. NADPH oxidase is an O2 sensor in airway chemoreceptors: evidence from KC current modulation in wild-type and oxidase-deficient mice. Proc Natl Acad Sci USA 2000; 97: 4374–4379.
   PubMed Web of Science ®Google Scholar
• Archer SL, Reeve HL, Michelakis E et al. O2 sensing is preserved in mice lacking the gp91Ph°x subunit of NADPH oxidase. Proc Natl Acad Sci USA 1999; 96: 7944–7949.
   PubMed Web of Science ®Google Scholar
• Osada M, Imaoka S, Sugimoto T, Hiroi T, Funae Y. NADPH-cytochrome P-450 reductase in the plasma membrane modulates the activation of hypoxia-inducible factor 1. J Biol Chem 2002; 277: 23367–23373.
   PubMed Web of Science ®Google Scholar
• Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc Natl Acad Sci USA 1998; 95: 11715–11720.
   PubMed Web of Science ®Google Scholar
• Chandel NS, McClintock DS, Feliciano CE et al. Reactive oxygen species generated at mitochondrial complexIII stabilize hypoxia-inducible factor-la during hypoxia: a mechanism of02 sensing. J Biol Chem 2000; 275: 25130–25138.
   PubMed Web of Science ®Google Scholar
• Kushnareva Y, Murphy AN, Andreyev A. Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P). oxidation-reduction state. Biochem J2002; 368: 545-553.
   Google Scholar
• Wainio WW. Reactions of cytochrome oxidase. J Biol Chem 1955; 212: 723–733.
   PubMed Web of Science ®Google Scholar
• Tatoyan A, Giulivi C. Purification and characterisation of a nitric-oxide synthase from rat liver mitochondria. J Biol Chem 1998; 273: 11044–11048.
   PubMed Web of Science ®Google Scholar
• Lazca Z, Puskar M, Figueroa JP, Zhang J, Rajapakse N, Busija DW. Mitochondria nitric oxide synthase is constitutively active and is functionally upregulated in hypoxia. Free Radic Biol Med 2001; 31: 1609–1615.
   PubMed Web of Science ®Google Scholar
• Sathananthan AH, Trounson AO. Mitochondrial morphology during preimplantation human embryogenesis. Human Reprod 2000;15(Suppl2): 148–159.
   PubMedGoogle Scholar
• Leese HJ. Metabolic control during preimplantation mammalian development. Hum Reprod Update 1995; 1: 63–72.
   PubMed Web of Science ®Google Scholar
• Trimarchi JR, Liu L, Porterfield DM, Smith PJ, Keefe DL. Oxidative phosphorylation-dependent and -independent oxygen consumption by individual preimplantation mouse embryos. Biol Reprod 2000; 62: 1866–1874.
   PubMed Web of Science ®Google Scholar
• Manes C, Lai NC. Non-mitochondrial oxygen utilisation by rabbit blastocysts and surface production of superoxide radicals. J Reprod Fertil 1995; 104: 69–75.
   PubMedGoogle Scholar
• Wu Z, Puigserver P. Andersson U et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999; 98: 115–124.
   PubMed Web of Science ®Google Scholar
• Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP. Peroxisome proliferator-activated receptor y coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest 2000; 106: 847–856.
   PubMed Web of Science ®Google Scholar
• Ichida M, Nemoto S, Finkel T. Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor y coactivator-1 a (PGC- la). J Biol Chem 2002; 277: 50991–50995.
   PubMed Web of Science ®Google Scholar
• Nisoli E, Clementi E, Paolucci C et al. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 2003;
   Google Scholar
• Tranguch S. Steuerwald N, Huet-Hudson YM. Nitric oxide synthase production and nitric oxide regulation of preimplantation embryo development. Biol Reprod 2003; 68:
   Google Scholar
• Nishikimi A, Matsukawa T, Hoshino K et al. Localization of nitric oxide synthase activity in unfertilized oocytes and fertilized
   Google Scholar
• Neganova IE, Sekirina GG, Eichenlaub-Ritter U. Surface-expressed E-cadherin, and mitochondrial and microtubule distribution in rescue of mouse embryos from 2-cell block by.
   Google Scholar
• Hunter CJ, Blood AB, White CR, Pearce WJ, Power GG. Role of nitric oxide in hypoxic cerebral vasodilatation in the ovine fetus.
   Google Scholar
• Seligman SP, Nishiwaki T, Kadner SS, Dancis J, Finlay TH. Hypoxia stimulates ecNOS mRNA expression by differentiated human trophoblasts. Ann NY Acad Sci 1997; 828: 180–187.
   PubMed Web of Science ®Google Scholar
• De Marco CS, Caniggia I. Mechanisms of oxygen sensing in.
   Google Scholar
• Genbacev O, Zhou Y, Ludlow JW, Fisher SJ. Regulation of human placental development by oxygen tension. Science 1997; 277: 1669–1672.
   PubMed Web of Science ®Google Scholar
• Frendo JL, Therond P, Bird T et al. Overexpression of copper.
   Google Scholar
• Cheng G, Cao Z, Xu X, van Meir EG, Lambeth JD. Homologs of gp91Ph": cloning and tissue expression of Nox3, Nox4, and.
   Google Scholar
• Manes C. Human placental NAD(P)H oxidase: solubilization and properties. Placenta 2001; 22: 58–63.
   PubMed Web of Science ®Google Scholar
• Novaro V. Colman-Lemer A, Ortega FV et al. Regulation of metalloproteinases by nitric oxide in human trophoblast cells in.
   Google Scholar
• Tse WK, Whitley GS, Cartwright JE. Transforming growth.
   Google Scholar
• Sumbayev VV, Budde A, Zhou J, Brune B. HIF-1 a protein as a.
   Google Scholar
• Barber A, Robson SC, Myatt L, Bulmer JN, Lyall F. Heme oxygenase expression in human placenta and placental bed: reduced expression of placenta endothelial HO-2 in preeclampsia.
   Google Scholar
• Lyall F. Development of the utero-placental circulation: the role of carbon monoxide and nitric oxide in trophoblast invasion and.
   Google Scholar
• Crews ST Control of cell lineage-specific development and transcription by bHLH-PAS proteins. Genes Dev 1998; 12: 607–620.
   PubMed Web of Science ®Google Scholar
• Iyer NV, Kotch LE, Agani F et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor la. Genes Dev 1998; 12: 149–162.
   PubMed Web of Science ®Google Scholar
• Kotch LE, Iyer NV, Laughner E, Semenza GL. Defective vascularization of HIF-la-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Dev Biol 1999; 209: 254–267.
   PubMed Web of Science ®Google Scholar
• Ryan HE, Lo J, Johnson RS. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J 1998; 17: 3005–3015.
   PubMed Web of Science ®Google Scholar
• Galson DL, Tsuchiya T, Tendler DS et al. The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1. Mol Cell Biol 1995; 15: 2135–2144.
   PubMed Web of Science ®Google Scholar
• Tsuchiya T, Kominato Y, Ueda M. Human hypoxic signal transduction through a signature motif in hepatocyte nuclear factor 4. J Biochem (Tokyo) 2002; 132: 37–44.
   PubMed Web of Science ®Google Scholar
• Discher DJ, Bishopric NH, Wu X, Peterson CA, Webster KA. Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Spl/5p3 binding to a conserved GC element. J Biol Chem 1998; 273: 26087–26093.
   PubMed Web of Science ®Google Scholar
• Braun H, Suske G. Combinatorial action of HNF3 and Sp family transcription factors in the activation of the rabbit uteroglobin/CC10 promoter. J Biol Chem 1998; 273: 9821-9828. Margana RK, Boggaram V. Functional analysis of surfactant protein B (SP-B) promoter. Spl, Sp3, TTF-1, and HNF-3a transcription factors are necessary for lung cell-specific activation of SP-B gene transcription. J Biol Chem 1997; 272: 3083–3090.
   PubMedGoogle Scholar
• Margana RK, Boggaram V. Functional analysis of surfactant protein B (SP-B) promoter. Sp1, Sp3, TTF-1, and HNF-3a transcription factors are necessary for lung cell-specific activation of SP-B gene transcription. J Biol Chem 1997; 272:3083–3090.
   PubMed Web of Science ®Google Scholar
• Zhao J, Sime PJ, Bringas Jr P, Gauldie J, Warburton D. Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-I3 type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA. Mech Dev 1998; 72: 89–100.
   PubMed Web of Science ®Google Scholar
• Vicencio AG, Eickelberg O, Stankewich MC, Kashgarian M, Haddad GG. Regulation of TGF-I3 ligand and receptor expression in neonatal rat lungs exposed to chronic hypoxia. J Appl Physiol 2002; 93: 1123–1130.
   PubMed Web of Science ®Google Scholar
• Perrella MA, Hsieh CM, Lee WS et al. Arrest of endotoxin-induced hypotension by transforming growth factor pl. Proc Natl Acad Sci USA 1996; 93: 2054–2059.
   PubMed Web of Science ®Google Scholar
• Young SL, Evans K, Eu JP. Nitric oxide modulates branching morphogenesis in fetal rat lung explants. Am J Physiol 2002; 282: L379–L385.
   Web of Science ®Google Scholar
• Shaul PW, Afshar S, Gibson LL et al. Developmental changes in nitric oxide synthase isoform expression and nitric oxide production in fetal baboon lung. Am J Physiol 2002; 283: L1192–L1199.
   Web of Science ®Google Scholar
• Barker PM, Olver RE. Clearance of lung liquid during the perinatal period. J Appl Physiol 2002; 93: 1542-1548. Canessa CM, Schild L, Buell G et al. Amiloride-sensitive epithelial Na. channel is made of three homologous subunits. Nature 1994; 367: 463–467.
   PubMedGoogle Scholar
• Canessa CM, Schild L, Buell G et al. Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits. Nature 1994; 367: 463–467.
   PubMed Web of Science ®Google Scholar
• Rafii B, Tanswell AK, Otulakowski G, Pitkanen O, Belcastro-Taylor R, O'Brodovich H. O2-induced ENaC expression is associated with NF-KB activation and blocked by superoxide scavenger. Am J Physiol 1998; 275: L764–L770.
   PubMed Web of Science ®Google Scholar
• Baines DL, Ramminger SJ, Collett A et al. Oxygen-evoked Na. transport in rat fetal distal lung epithelial cells. J Physiol 2001; 532: 105–113.
   PubMed Web of Science ®Google Scholar
• Wang H-C, Aenter MD, Deng H-T et al. Oxidative stress disrupts glucocorticoid hormone-dependent transcription of the amiloride sensitive epithelial sodium channel a-subunit in lung epithelial cells through ERK-dependent and thioredoxin sensitive pathways. J Biol Chem 2000; 275: 8600–8609.
   PubMed Web of Science ®Google Scholar
• Baines DL, Janes M, Newman DJ, Best OG. Oxygen-evoked changes in transcriptional activity of the 5'-flanking region of the human amiloride-sensitive sodium channel (aENaC) gene: role of nuclear factor1c13. Biochem J2002; 364: 537–545.
   PubMed Web of Science ®Google Scholar
• Haddad JJ, Collett A, Land SC, Olver RE, Wilson SM. NF-KB blockade reduces the O2-evoked rise in Na. conductance in fetal alveolar cells. Biochem Biophys Res Commun 2001; 281: 987–992.
   PubMed Web of Science ®Google Scholar
• Richard K, Ramminger SJ, Inglis SK, Olver RE, Land SC, Wilson SM. O2 can raise fetal pneumocyte Na. conductance without affecting ENaC mRNA abundance. Biochem Biophys Res Commun 2003; 305: 671–676.
   PubMed Web of Science ®Google Scholar
• Wendt CH, Gick G, Sharma R, Zhuang Y, Deng W, Ingbar DH. Up-regulation of Na,K-ATPase β1 transcription by hyperoxia is mediated by SP1/5P3 binding. J Biol Chem 2000; 275: 41396–41404.
   PubMed Web of Science ®Google Scholar
• Dada LA, Chandel NS, Ridge KM, Pedemonte C, Bertorello AM, SznajderJI. Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-z. J Clin Invest 2003; 111: 1057–1064.
   PubMed Web of Science ®Google Scholar
• Planes C, Blot-Chabaud M, Matthay MA, Couette S, Uchida T, Clerici C. Hypoxia and O2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells. J Biol Chem 2002; 277: 47318–47324.
   PubMed Web of Science ®Google Scholar
• Eskes TKAB, Jongsma HW, Houx PCW. Percentiles for gas values in human umbilical cord blood. Eur J Obstet Gynaecol Reprod Biol 1983; 14: 341–346.
   PubMed Web of Science ®Google Scholar
• Rurak D, Selke P, Fisher M, Taylor AHT, Whitmann B. Fetal oxygen extraction: comparison of the human and sheep. Am J Obstet Gynecol 1987; 156: 360–366.
   PubMed Web of Science ®Google Scholar
• Yeomans ER, Hauth JC, Gil strapIII LC, Strickland DM. Umbilical cord pH, PCO2 and bicarbonate following uncomplicated term vaginal deliveries. Am J Obstet Gynecol 1985; 151: 798–800.
   Google Scholar
• Jauniaux E, Kiserud T, Ozturk0, West D, Hanson MA. Amniotic gas exchange and acid-base status during acute maternal hyperoxemia and hypoxemia in the early fetal sheep. Am J Obstet Gynecol 2000; 182: 661–665.
   Google Scholar
• Sutton JR, Reeves JT, Groves BM et al. Oxygen transport and cardiovascular function at extreme altitude: lessons from Operation Everest II. Int J Sports Med 1997;13(Suppl1): S13–S18.
   Google Scholar
• Leese HJ. Metabolism of the preimplantation embryo. Oxf Rev Reprod Biol 1991; 13: 35–72.
   PubMedGoogle Scholar
• Bell AW, Battaglia FC, Makowski EL, Meschia G. Relationship between metabolic rate of body size in fetal life. Biol Neonate 1985; 47: 120–123.
   PubMedGoogle Scholar
• Nozik-Grayck E, Piantadosi CA, van Adelsberg J, Alper SL, Huang YC. Protection of perfused lung from oxidant injury by inhibitors of anion exchange. Am J Physiol 1997; 273: L296–L304.
   PubMed Web of Science ®Google Scholar
• Chandel NS, Vander Heiden MG, Thompson CB, Schumacker PT. Redox regulation of p53 during hypoxia. Oncogene 2000; 19: 3840-3848.
   Google Scholar
• Page K. The Physiology of the Human Placenta. London: UCL Press, 1993.
   Google Scholar