Publication Cover
Redox Report
Communications in Free Radical Research
Volume 10, 2005 - Issue 1
1,906
Views
160
CrossRef citations to date
0
Altmetric
Research Articles

Electron paramagnetic resonance study of the generation of reactive oxygen species catalysed by transition metals and quinoid redox cycling by inhalable ambient particulate matter

, , &
Pages 37-51 | Published online: 19 Jul 2013

References

  • Seaton A, MacNee W, Donaldson K, Godden D. Particulate air pollution and acute health effects. Lancet 1995; 345: 176–178.
  • Brunekreef B, Holgate ST. Air pollution and health. Lancet 2002; 360: 1233–1242.
  • Pope III CA, Burnett RT, Thun MJ et al. Lung cancer, cardiopulmonary mortality and long-term exposure to fine particulate air pollution. JAMA 2002; 287: 1132–1141.
  • Dockery DW, Pope III CA, Xiping XU, Spengler JD, Ware ill, Fay ME. An association between air pollution and mortality in six US cities. N Engl J Med 1993; 329: 1753–1759.
  • Pope III CA, Thun MJ, Namboodiri MM et al. Particulate air pollution as a predictor of mortality in a prospective study of US adults. Am J Respir Grit Care Med 1995; 151: 669–674.
  • Abbey DE, Nishino N, McDonnell WF et al. Long-term inhalable particles and other pollutants related to mortality in nonsmokers. Am J Respir Grit Care Med 1999; 159: 373–382.
  • Nyberg F, Gustavsson P, Japur L et al. Urban air pollution and lung cancer in Stockholm. Epidemiology 2000; 11: 487–495.
  • Samet JM, Dominici F, Zeger SL, Schwartz J, Dockery DW. The National Morbidity, Mortality, and Air Pollution Study. Part. 1: methods and methodological issues. Research Report. Health Effects Institute 2000; 75: 5–14.
  • Samet JM, Dominici F, Currier° FC, Coursac I, Zeger SL. Fine particulate air pollution and mortality in 20 cities, 1987-1994. N Engl J Med 2000; 343: 1742–1749.
  • Katsouyanni K, Zmirou D, Spix C et al. Short-term effects of air pollution on health: a European approach using epidemiological time-series data. The APHEA project: background, objectives, design. Eur Respir J1995; 8: 1030-1038.
  • Katsouyanni K, Touloumi G, Samoli E et al. Confounding and effect modification in the short-term effects of ambient particles on total mortality: results from 29 European cities within the APHEA2 project. Epidemiology 2001; 12: 521–531.
  • Kelly FJ. Oxidative stress: its role in air pollution and adverse health effects. Occup Environ Health 2003; 60: 612–616.
  • Nel AE, Diaz-Sanchez D, Li N. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr Opin Pulmon Med 2001; 7: 20–26.
  • Gauderman WJ, McConnell R, Gilliland F et al. Association between air pollution and lung function growth in southern California children. Am J Respir Grit Care Med 2000; 162: 1383–1390.
  • Li N, Kim S, Wang M, Froines J, Sioutas C, Nel A. Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhal Toxicol 2002; 14: 459–486.
  • Martin LD, Krunkosky TM, Dye JA et al. The role of reactive oxygen and nitrogen species in the response of airway epithelium to particles. Environ Health Perspect 1997; 105: 1301–1307.
  • Bai Y, Suzuki A, Sagai M. The cytotoxic effects of diesel exhaust particles on human pulmonary artery endothelial cells in vitro: role of active oxygen species. Free Radic Biol Med 2001; 30: 555–562.
  • Li N, Venkatesan I, Migue A et al. Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element. J Immunol 2000; 165: 3393–3401.
  • Samet JM, Pepelko WE, Sonawane B, Hatch GE, Driscoll KE, Oberdorster G. Risk assessment of oxidant gases and particulate air pollutants: uncertainties and research needs. Environ Health Perspect 1994; 102 (Suppl 10): 209–214.
  • Fujii T, Hayashi S, Hogg JC, Vincent R, Van Eeden SF. Particulate matter induces cytokine expression in human bronchial epithelial cells. Am J Respir Cell Mol Biol 2001; 25: 265–271.
  • Lundborg M, Johard U, Lastbom L, Gerde P, Cammer P. Human alveolar macrophage phagocytic function is impaired by aggregates of ultrafme carbon particles. Environ Res 2001; 86: 244–253.
  • Delinger B, Pryor WA, Cueto R, Squadrito GL, Hedge V, Deutch WA. Role of free radicals in the toxicity of airborne fine particulate matter. Chem Res Toxicol 2001; 14: 1371–1377.
  • Ferin J, Oberdoster G, Penney DP. Pulmonary retention of ultra-fine and fine particles in rats. Am J Respir Cell Mol Biol 1992; 6: 535–542.
  • Brown DM, Wilson MR, MacNee W, Stone V, Donaldson K. Size-dependent proinflammatory effects of ultrafine polystyrene particles: the role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol Appl Pharmacol 2001; 175: 191–199.
  • Churg A, Brauer M. Ambient atmospheric particles in the airways of human lungs. Ultrastruct Pathol 2000; 24: 353–361.
  • Churg A, Brauer M. Human lung parenchyma retains PM25. Am J Respir Grit Care Med 1997; 155: 2109–2111.
  • Dreher K, Jaskot R, Kodavanti U, Lehmann J, Winsett D, Costa D. Soluble transition metals mediate the acute pulmonary injury and airway hyperreactivity by residual oil fly ash particles. Chest 1996; 109: 541–554.
  • Ghio AJ, Kennedy TP, Whorton AR, Crumbliss AL, Hatch GE, Hoidal JR. Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. Am J Physiol 1992; 263: L511–L518.
  • Donaldson K, Brown DM, Mitchell C et al. Free radical activity of PM50: iron-mediated generation of hydroxyl radicals. Environ Health Perspect 1997; 105: 1285–1289.
  • Valavanidis A, Salika A, Theodoropoulou A. Generation of hydroxyl radicals by urban suspended particulate air matter. The role of iron ions. Atmospher Environ 2000; 34: 2379–2386.
  • Pritchard RJ, Ghio AJ, Lehmann JR et al. Oxidant generation and lung injury after exposure to particulate air pollutants are associated with concentrations of complexed iron. Inhal Toxicol 1996; 8: 457–477.
  • Van Maaren JMS, Borm PJA, Knaapen A et al. In vitro effects of coal fly ash: hydroxyl radical generation, iron release, and DNA damage and toxicity in rat lung epithelial cells. Inhal Toxicol 1999; 11: 1123–1141.
  • Zang L-Y, Stone K, Pryor WA. Detection of free radicals in aqueous extracts of cigarette tar by electron spin resonance. Free Radic Biol Med 1995; 19: 161–167.
  • Ross MM, Chedekel MR, Risby TH. Electron paramagnetic resonance spectrometry of diesel particulate matter. Environ Int 1982; 7: 325–329.
  • Church DF, Pryor WA. Free-radical chemistry of cigarette smoke and its toxicological implications. Environ Health Perspect 1985; 64: 111–126.
  • Squadrito GL, Cueto R, Dellinger B, Pryor WA. Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne particulate matter. Free Radic Biol Med 2001; 31: 1132–1138.
  • Kumagai Y, Taira J, Sagai M. Apparent inhibition of superoxide dismutase activity in vitro by diesel exhaust particles. Free Radic Biol Med 1995; 18: 365–371.
  • Roginsky VA, Barsukova TK, Stegmann HB. Kinetics of redox interaction between substituted quinones and ascorbate under aerobic conditions. Chembiol Interact 1999; 121: 177–197.
  • Qui XB, Cadenas E. The role of NAD(P)H: quinone oxidoreductasein quinone-mediated p21 induction in human colon carcinoma cells. Arch Biochem Biophys 1997; 346: 241–251.
  • Hirakawa K, Oikawa S, Hiraku Y, Hirosawa I, Kawanishi S. Catechol and hydroquinone have different redox properties responsible for their differential DNA-damaging ability. Chem Res Toxicol 2002; 15: 76–82.
  • Bolton JL, Trash MA, Penning TM, Dryhurst G, Monks TJ. Role of quinones in toxicology. Chem Res Toxicol 2000; 13: 135–160.
  • Qui X, Forman HJ, Schonthal AH, Cadenas E. Induction of p21 mediated oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells. J Biol Chem 1996; 271: 31915–31921.
  • Gelboin H.V. Benzo[a]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed function oxidases and related enzymes. Physiol Rev 1980; 60: 1107–1166.
  • Thakker DR, Yagi H, Lu AYH, Levin W, Conney AH, Jerina DM. Metabolism of benzo[a]pyrene: conversion of (±)-trans-7, 8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-dio1-9,10-epoxides. Proc Natl Acad Sci USA 1976; 73: 3381–3385.
  • Dennisenko MF, Pao A, Tang M-S, Pfeifer GP. Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in p53. Carcinogenesis 1996; 14: 475–482.
  • Cavalieri EL, Rogan EG. Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons. Xenobiotica 1995; 25: 677–688.
  • Flowers L, Bleczinski WF, Burczynski ME, Harvey RG, Penning TM. Disposition and biological activity of benzo[a]pyrene-7,8-dione: a genotoxic metabolite generated by dihydrodiol dehydrogenase. Biochemistry 1996; 35: 13664–13672.
  • Ohnishi S, Kawanishi S. Double base lesions of DNA by a metabolite of carcinogenic benzo[a]pyrene. Biochem Biophys Res Commun 2002; 290: 778–782.
  • Li Y, Trash, MA. Reactive oxygen-dependent DNA damage resulting from the oxidation of phenolic compounds by a copper-redox cycle mechanism. Cancer Res 1994; 54: 1895s-1898s.
  • Li Y, Kuppusamy P, Zweier JL, Trash MA. ESR evidence for the generation of reactive oxygen species from the copper-mediated oxidation of the benzene metabolite, hydroquinone: role in DNA damage. Chembiol Interact 1995; 94: 101–120.
  • Li N, Kim S, Wang M, Froines J, Sioutas C, Nel A. Use of a stratified oxidative stress model to study the biological effects of ambient concentrated and diesel exhaust particulate matter. Inhal Toxicol 2002; 14: 459–486.
  • Knaapen AM, Shi T, Borm PJA, Schins RPF. Soluble metals as well as insoluble particle fraction are involved in cellular DNA damage induced by particulate matter. Mol Cell Biochem 2002; 234/235: 317–326.
  • Arudi RL, Allen AO, Bielski BH. Some observations on the chemistry of K02-DMS0 solutions. FEBS Lett 1981; 135: 265–267.
  • Sagai M, Saito H, Ichinose T, Kodama M, Mori Y. Biological effects of diesel exhaust particles. I. In vitro production of superoxide and in vivo toxicity in mouse. Free Radic Biol Med 1993; 14: 37–47.
  • Pryor AA, Stone K, Zang L-Y, Bermudez E. Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage. Chem Res Toxicol 1998; 11: 441–448.
  • Pryor WA, Hales BJ, Premovic PI, Church DF. The radicals of cigarette tar: their nature and suggested physiological implications. Science 1983; 220: 425–427.
  • Scheff PA, Valiozis C. Characterization and source identification of respirable particulate matter in Athens, Greece. Atmospher Environ 1995; 24A: 203–211.
  • Graft E, Mahoney JR, Bryant BG, Eaton JW. Iron-catalyzed hydroxyl radical formation. J Biol Chem 1984; 259: 3620–3624.
  • Kumagai Y, Arimoto T, Shinyashiki M et al. Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochorome P450 reductase and involvement of the bioactivation in the DNA damage. Free Radic Biol Med 1997; 22: 479–487.
  • Ball JC, Straccia AM, Young WC, Aust AE. The formation of reactive oxygen species catalyzed by neutral, aqueous extracts of NIST ambient particulate matter and diesel engine particles. J Air Waste Manag Assoc 2000; 50: 1897–1903.
  • Marsall BT, Patterson EM, Grams GW. Characterization of the Atlanta area aerosol, elemental composition and possible sources. Atmospher Environ 1986; 20: 1291–1300.
  • Espinosa JFA, Podriguez MT, Barragan de la Rosa JF, Sanchez CH. Size distribution in urban aerosols in Seville (Spain). Atmospher Environ 2001; 35: 2595–2601.
  • Fine PM, Cass GR, Simoneit BRT. Chemical characterization of fine particle emissions from the fireplace combustion of woods grown in the southern United States. Environ Sci Technol 2002; 36: 1442–1451.
  • Leonard SS, Wang S, Shi X, Jordan BS, Castranova V, Dubick MA. Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NF-KB activation and TNF-a release in macrophages. Toxicology 2000; 150: 147–157.
  • Cho AK, Di Stefano E, You Yet al. Determination of four quinones in diesel exhaust particles, SRM 1649a, and atmospheric PM25. Aerosol Sci Technol 2004; 38: 68–81.
  • Purvis CR, McCrillis RC, Kariher PH. Fine particulate matter (PM) and organic speciation of fireplace emissions. Environ Sci Technol 2000; 34: 1653–1658.
  • Cadle SH, Mulawa P, Groblicki P et al. In-use light-duty gasoline vehicle particulate matter emissions on three driving cycles. Environ Sci Technol 2001; 35: 26–32.
  • Koeber R, Bayona JIM, Niessner R. Determination of benzo[a]pyrene diones in air particulate matter with liquid chromatography mass spectrometry. Environ Sci Technol 1999; 33: 1552–1558.
  • Penning TM, Burczynski ME, Hung C-H et al. Dihydrodiol dehydrogenases and polycyclic aromatic hydrocarbon activities: generation of reactive and redox active o-quinones. Chem Res Toxicol 1999; 12: 1–18.
  • Shi T, Schins RPF, Knaapen AM et al. Hydroxyl radical generation by electron paramagnetic resonance as a new method to monitor ambient particulate matter composition. J Environ Monitor 2003; 5: 550–556.
  • Kappus H. Overview of enzyme systems involved in bio-reduction of drugs and in redox cycling. Biochem Pharmacol 1986; 35: 1–6.
  • Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V. Interaction between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 2002; 184: 172–179.
  • Gavett SH, Haykal-Coates N, Copeland LB, Heinrich J, Gilmour MI. Metal composition of ambient PM25 influences severity of allergic airways disease in mice. Environ Health Perspect 2003; 111: 1471–1477.
  • Burton RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1985; 18: 775–794.
  • Sullivan PD. Free radical of benzo(a)pyrene and derivatives. Environ Health Perspect 1985; 64: 283–295.
  • Nachtman JP. Superoxide generation by 1-nitropyrene in rat lung microsomes. Res Commun Pathol Pharmacol 1986; 51: 73–80.
  • Sorensen M, Autrup H, Moller P et al. Linking exposure to environmental pollutants with biological effects. Mutat Res 2003; 544: 255–271.
  • Smith KR, Aust AE. Mobilization of iron from urban particulates leads to generation of reactive oxygen species in vitro and induction of ferritin synthesis in human lung epithelial cells. Chem Res Toxicol 1997; 10: 828–834.
  • Burkitt MJ, Gilbert BC. The autoxidation of iron(III) in aqueous systems: the effect of iron chelation by physiological, non-physiological and therapeutic chelators on the generation of reactive oxygen species and the inducement of biomolecular damage. Free Radic Res Commun 1991; 14: 107–123.
  • Gutteridge JMC, Richmond R, Halliwell B. Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and of lipid peroxidation by desferrioxamine. Biochem J1979; 184: 469-472.
  • Pan C-JG, Schmitz DA, Cho AK, Froines J, Fukuto JM. Inherent redox properties of diesel exhaust particles: catalysis of the generation of reactive oxygen species by biological reductants. Toxicol Sci 2004; 81: 225–232.
  • Xia T, Korge P, Weiss JN et al. Quinones and aromatic chemical compounds in particle matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environ Health Perspect 2004; 112: 1347–1358.
  • Henry TR, Wallace KB. Differential mechanisms of cell killing by redox cycling and arylating quinines. Arch Toxicol 1996; 70: 482–489.
  • Prahalad AK, Inmon J, Dailey LA, Madden MC, Ghio AJ, Gallagher JE. Air pollution particles mediated oxidative DNA base damage in a cell free system and in human airway epithelial cells in relation to particulate metal content and bioreactivity. Chem Res Toxicol 2001; 4: 879–887.
  • Wilson MR, Lightbody JH, Donaldson K, Sales J, Stone V. Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol 2002; 184: 172–179.
  • Shi T, Knaapen AM, Begerow J, Birmili W, Borm PJ, Schins RP. Temporal variation of hydroxyl radical generation and 8-hydroxy-2'-deoxyguanosine formation by coarse and fine particulate matter. Occup Environ Med 2003; 60: 315–321.
  • Upadhyay D, Panduri V, Ghio A, Kamp DW. Particulate matter induces alveolar epithelial cell DNA damage and apoptosis: role of free radicals and the mitochondria. Am J Respir Cell Mol Biol 2003; 29: 180–187.
  • Toa F, Gonzalez-Flecha B, Korbzik L. Reactive oxygen species in pulmonary inflammation by ambient particulates. Free Radic Biol Med 2003; 35: 327–340.
  • Gurgueira SA, Lawrence J, Coull B, Murthy GG, Gonzalez-Flecha B. Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation. Environ Health Perspect 2002; 110: 749–755.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.