Publication Cover
Redox Report
Communications in Free Radical Research
Volume 18, 2013 - Issue 3
1,143
Views
19
CrossRef citations to date
0
Altmetric
Research articles

Effect of induced mild hypothermia on two pro-inflammatory cytokines and oxidative parameters during experimental acute sepsis

, , , &
Pages 120-126 | Published online: 15 Nov 2013

References

  • Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003;31:1250–6.
  • Gerlach H, Toussaint S. Organ failure in sepsis. Curr Infect Dis Rep 2007;9:374–81.
  • Schmittinger CA, Wurzinger B, Deutinger M, Wohlmuth C, Knotzer H, Torgersen C, et al. How to protect the heart in septic shock: a hypothesis on the pathophysiology and treatment of septic heart failure. Med Hypotheses 2010;74:460–5.
  • Blackwell TS, Christman JW. Sepsis and cytokines: current status. Br J Anaesth 1996;77:110–7.
  • Pinsky MR, Vincent JL, Deviere J, Alegre M, Kahn RJ, Dupont E. Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest 1993;103:565–75.
  • Taylor DE, Piantadosi CA. Oxidative metabolism in sepsis and sepsis syndrome. J Crit Care 1995;10:122–35.
  • Macdonald J, Galley HF, Webster NR. Oxidative stress and gene expression in sepsis. Br J Anaesth 2003;90:221–32.
  • Biswal S, Remick DG. Sepsis: redox mechanisms and therapeutic opportunities. Antioxid Redox Signal 2007;9:1959–61.
  • Victor VM, Rocha M, Esplugues JV, De la Fuente M. Role of free radicals in sepsis: antioxidant therapy. Curr Pharm Des 2005;11:3141–58.
  • Goode HF, Cowley HC, Walker BE, Howdle PD, Webster NR. Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction. Crit Care Med 1995;23:646–51.
  • Price S, Anning PB, Mitchell JA, Evans TW. Myocardial dysfunction in sepsis: mechanisms and therapeutic implications. Eur Heart J 1999;20:715–24.
  • L'Her E, Amerand A, Vettier A, Sebert P. Effects of mild induced hypothermia during experimental sepsis. Crit Care Med 2006;34:2621–3.
  • Léon K, Pichavant-Rafini K, Quemener E, Sébert P, Egreteau PY, Ollivier H, et al. Oxygen blood transport during experimental sepsis: Effect of hypothermia. Crit Care Med 2012;40:912–8.
  • Vigue B, Geeraerts T, Le Guen M, Engrand N, Ract C. Therapeutic hypothermia. Ann Fr Anesth Reanim 2006;25:838–44.
  • Moore EM, Nichol AD, Bernard SA, Bellomo R. Therapeutic hypothermia: benefits, mechanisms and potential clinical applications in neurological, cardiac and kidney injury. Injury 2011;42:843–54.
  • Polderman KH. Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 2009;37:S186–202.
  • Weinrauch V, Safar P, Tisherman S, Kuboyama K, Radovsky A. Beneficial effect of mild hypothermia and detrimental effect of deep hypothermia after cardiac arrest in dogs. Stroke 1992;23:1454–62.
  • Rittirsch D, Huber-Lang MS, Flierl MA, Ward PA. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 2009;4:31–6.
  • Coudray C, Favier A. Determination of salicylate hydroxylation products as an in vivo oxidative stress marker. Free Radic Biol Med 2000;29:1064–70.
  • Halliwell B, Kaur H, Ingelman-Sundberg M. Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note. Free Radic Biol Med 1991;10:439–41.
  • Amerand A, Vettier A, Sebert P, Cann-Moisan C. In vitro effect of hydrostatic pressure exposure on hydroxyl radical production in fish red muscle. Redox Rep 2005;10:25–8.
  • Mortelette H, Amerand A, Sebert P, Belhomme M, Calves P, Moisan C. Effect of exercise training on respiration and reactive oxygen species metabolism in eel red muscle. Respir Physiol Neurobiol 2010;172:201–5.
  • Sebert P, Menez JF, Simon B, Barthelemy L. Effects of hydrostatic pressure on malondialdehyde (MDA) determination in brain from yellow freshwater eels. C R Acad Sci III 1995;318:757–60.
  • Peres Bota D, Lopes Ferreira F, Melot C, Vincent JL. Body temperature alterations in the critically ill. Intensive Care Med 2004;30:811–6.
  • Gogos CA, Drosou E, Bassaris HP, Skoutelis A. Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options. J Infect Dis 2000;181:176–80.
  • Rim KP, Kim K, Jo YH, Lee JH, Rhee JE, Kang KW, et al. Effect of therapeutic hypothermia according to severity of sepsis in a septic rat model. Cytokine 2012;60:755–61.
  • Webster CM, Kelly S, Koike MA, Chock VY, Giffard RG, Yenari MA. Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol Dis 2009;33:301–12.
  • Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003;348:138–50.
  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44–84.
  • Ritter C, Andrades M, Moreira JC, Dal-Pizzol F. Antioxidants and sepsis: can we find the ideal approach? Crit Care Med 2004;32:1445–6.
  • Bayir H, Adelson PD, Wisniewski SR, Shore P, Lai Y, Brown D, et al. Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med 2009;37:689–95.
  • Huet O, Kinirons B, Dupic L, Lajeunie E, Mazoit JX, Benhamou D, et al. Induced mild hypothermia reduces mortality during acute inflammation in rats. Acta Anaesthesiol Scand 2007;51:1211–6.
  • Polderman KH, Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods. Crit Care Med 2009;37:1101–20.
  • Demirbilek S, Ersoy MO, Demirbilek S, Karaman A, Akin M, Bayraktar M, et al. Effects of polyenylphosphatidylcholine on cytokines, nitrite/nitrate levels, antioxidant activity and lipid peroxidation in rats with sepsis. Intensive Care Med 2004;30:1974–8.
  • Wu X, Stezoski J, Safar P, Bauer A, Tuerler A, Schwarz N, et al. Mild hypothermia during hemorrhagic shock in rats improves survival without significant effects on inflammatory responses. Crit Care Med 2003;31:195–202.
  • Giusti-Paiva A, Martinez MR, Felix JV, da Rocha MJ, Carnio EC, Elias LL, et al. Simvastatin decreases nitric oxide overproduction and reverts the impaired vascular responsiveness induced by endotoxic shock in rats. Shock 2004;21:271–5.
  • Scumpia PO, Sarcia PJ, DeMarco VG, Stevens BR, Skimming JW. Hypothermia attenuates iNOS, CAT-1, CAT-2, and nitric oxide expression in lungs of endotoxemic rats. Am J Physiol Lung Cell Mol Physiol 2002;283:L1231–8.
  • Kuhn LA, Turner JK. Alterations in pulmonary and peripheral vascular resistance in immersion hypothermia. Circ Res 1959;7:366–74.
  • Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, et al. Fever control using external cooling in septic shock: a randomized controlled trial. Am J Respir Crit Care Med 2012;185:1088–95.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.