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Redox Report
Communications in Free Radical Research
Volume 21, 2016 - Issue 1
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Research Article

Impact of lithium alone or in combination with haloperidol on selected oxidative stress parameters in human plasma in vitro

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References

  • Connolly KR, Thase ME. The clinical management of bipolar disorder: a review of evidence-based guidelines. Prim Care Companion CNS Disord 2011;13(4): PCC.10r01097.
  • Cipriani A, Hawton K, Stockton S, Geddes JR. Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. BMJ 2013;346:f3646. doi: 10.1136/bmj.f3646.
  • Machado-Vieira R, Manji HK, Zarate Jr CA. The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis. Bipolar Disord 2009;11(Suppl. 2):92–109. doi: 10.1111/j.1399-5618.2009.00714.x.
  • Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997;82:291–5. doi: 10.1113/expphysiol.1997.sp004024
  • Rice-Evans CA, Diplock AT, Symons MCR. Techniques in free radical research. Amsterdam, London, New York, Tokyo: Elsevier; 1991.
  • Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cationdecolorization assay. Free Radic Biol Med 1999;26(9–10):1231–7. doi: 10.1016/S0891-5849(98)00315-3
  • Berk M, Kapczinski F, Andreazza AC, Dean OM, Giorlando F, Maes M, et al. Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors. Neurosci Biobehav Rev 2011;35:804–17. doi: 10.1016/j.neubiorev.2010.10.001
  • Singh OP, Chakraborty I, Dasgupta A, Datta S. A comparative study of oxidative stress and interrelationship of important antioxidants in haloperidol and olanzapine treated patients suffering from schizophrenia. Indian J Psychiatry 2008;50:171–6. doi: 10.4103/0019-5545.43627
  • Lepping P, Delieu J, Mellor R, Williams JHH, Hudson PR, Hunter-Lavin CJ. Antipsychotic medication and oxidative cell stress: a systematic review. J Clin Psychiatry 2011;72(3):273–85. doi: 10.4088/JCP.09r05268yel
  • Abdalla DSP, Bechara EJH. The effect of chlorpromazine and Li2CO3 on the superoxide dismutase and glutathione peroxidase activities of rat brain, liver and erythrocytes. Biochem Mol Biol Int 1994;34:1085–90.
  • Malhotra A, Dhawan DK. Zinc improves antioxidative enzymes in red blood cells and hematology in lithium-treated rats. Nutr Res 2008;28(1):43–50. doi: 10.1016/j.nutres.2007.11.002
  • Nciri R, Desmoulin F, Allagui MS, Murat JC, Feki AE, Vincent C, et al. Neuroprotective effects of chronic exposure of SH-SY5Y to low lithium concentration involve glycolysis stimulation, extracellular pyruvate accumulation and resistance to oxidative stress. Int J Neuropsychopharmacol 2013;16(2):365–76. doi: 10.1017/S1461145712000132
  • Machado-Vieira R, Andreazza AC, Viale CI, Zanatto V, Cereser Jr V, da Silva Vargas R, et al. Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: a possible role for lithium antioxidant effects. Neurosci Lett 2007;421:33–6. doi: 10.1016/j.neulet.2007.05.016
  • Aliyazicioglu R, Kural B, Colak M, Karahan SC, Ayvaz S, Deger O. Treatment with lithium, alone or in combination with olanzapine, relieves oxidative stress but increases aterogenic lipids in bipolar disorder. Tohoku J Exp Med 2007;213:79–87. doi: 10.1620/tjem.213.79
  • Khairova R, Pawar R, Salvadore G, Juruena MF, de Sousa RT, Soeiro-de-Souza MG, et al. Effects of lithium on oxidative stress parameters in healthy subjects. Mol Med Rep 2012;5(3):680–2. doi:10.3892/mmr.2011.732.
  • Ulrich S, Neuhof S, Braun V, Meyer FP. Therapeutic window of serum haloperidol concentration in acute schizophrenia and schizoaffective disorder. Pharmacopsychiatry 1998;31(5):163–9. doi: 10.1055/s-2007-979322
  • Nciri R, Allagui MS, Vincent C, Murat JC, Croute F, El Feki A. Chronic lithium administration triggers an over-expression of GRP94 stress protein isoforms in mouse liver. Food Chem Toxicol 2010;48:1638–43. doi: 10.1016/j.fct.2010.03.038
  • Shin JH, Cho SI, Lim HR, Lee JK, Lee YA, Noh JS, et al. Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of ALS. Mol Pharmacol 2007;71:965–75. doi: 10.1124/mol.106.030676
  • Shao L, Young LT, Wang JF. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry 2005;58:879–84. doi: 10.1016/j.biopsych.2005.04.052
  • LaiJ S, Zhao Z, Warsh JJ, Li PP. Cytoprotection by lithium and valproate varies between cell types and cellular stresses. Eur J Pharmacol 2006;539:18–26. doi: 10.1016/j.ejphar.2006.03.076
  • Kiełczykowska M, Pasternak K, Musik I, Wrońska-Tyra J, Hordyjewska A. The influence of different doses of lithium administered in drinking water on lipid peroxidation and the activity of antioxidant enzymes in rats. Polish J Environ Stud 2006;15:747–51.
  • Bhalla P, Dhawan DK. Protective role of lithium in ameliorating the aluminium-induced oxidative stress and histological changes in rat brain. Cell Mol Neurobiol 2009;29(4):513–21. doi: 10.1007/s10571-008-9343-5
  • Castro AA, Casagrande TS, Moretti M, Constantino L, Petronilho F, Guerra GCB, et al. Lithium attenuates behavioral and biochemical effects of neuropeptide S in mice. Peptides 2009;30:1914–20. doi: 10.1016/j.peptides.2009.07.004
  • Song C, Killeen AA, Leonard BE. Catalase, superoxide dismutase and glutathione peroxidase activity in neutrophils of sham-operated and olfactory-bulbectomised rats following chronic treatment with desipramine and lithium chloride. Neuropsychobiology 1994;30:24. doi: 10.1159/000119131
  • Frey BN, Valvassori SS, Réus GZ, Martins MR, Petronilho FC, Bardini K, et al. Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania. J Psychiatry Neurosci 2006;31:326–32.
  • JornadaL K, Valvassori SS, Steckert AV, Moretti M, Mina F, Ferreira CL, et al. Lithium and valproate modulate antioxidant enzymes and prezentouabain-induced oxidative damage in an animal model of mania. J Psychiatr Res 2011;45:162–8. doi: 10.1016/j.jpsychires.2010.05.011
  • Albayrak A, Halici Z, Polat B, Karakus E, Cadirci E, Bayir Y, et al. Protective effects of lithium: a new look at an old drug with potential antioxidative and anti-inflammatory effects in an animal model of sepsis. Int Immunopharmacol 2013;16:35–40. doi: 10.1016/j.intimp.2013.03.018
  • Vasconcellos APS, Nieto FB, Crema LM, Diehl LA, Almeida LM, Prediger ME, et al. Chronic lithium treatment has antioxidant properties but does not prevent oxidative damage induced by chronic variate stress. Neurochem Res 2006;31:1141–51. doi: 10.1007/s11064-006-9139-2
  • Chadha VD, Bhalla P, Dhawan DK. Zinc modulates lithium-induced hepatotoxicity in rats. Liver Int 2008;28(4):558–65. doi: 10.1111/j.1478-3231.2008.01674.x
  • Oktem F, Ozguner F, Sulak O, Olgar S, Akturk O, Yilmaz HR. Lithium-induced renal toxicity in rats: protection by a novel antioxidant caffeic acid phenethyl ester. Mol Cell Biochem 2005;277:109–115. doi: 10.1007/s11010-005-5426-5
  • Sahin O, Sulak O, Yavuz Y, Uz E, Eren I, Yilmaz HR, et al. Lithium-induced lung toxicity in rats: the effect of caffeic acid phenethyl ester (CAPE). Pathology 2006;38(1):58–62. doi: 10.1080/00313020500464904
  • Banerjee U, Dasgupta A, Rout JK, Singh OP. Effects of lithium therapy on Na(+)-K(+)-ATPase activity and lipid peroxidation in bipolar disorder. Prog Neuropsychopharmacol Biol Psychiatry 2012;37(1):56–61. doi: 10.1016/j.pnpbp.2011.12.006.
  • Cohen WJ, Cohen NH. Lithium carbonate, haloperidol, and irreversible brain damage. JAMA 1974;230(9):1283–7. doi: 10.1001/jama.1974.03240090023018
  • Colvard MD, Gentry JD, Mullis DM. Neurotoxicity with combined use of lithium and haloperidol decanoate. Prim Care Companion CNS Disord 2013;15(6). pii:PCC.13l01563. doi:10.4088/PCC.13l01563.
  • Goldman SA. Lithium and neuroleptics in combination: is there enhancement of neurotoxicity leading to permanent sequelae? J Clin Pharmacol 1996;36(10):951–62. doi: 10.1002/j.1552-4604.1996.tb04763.x
  • Nemes ZC, Volavka J, Lajtha A, Cooper TB, Sershen H. Concurrent lithium administration results in higher haloperidol levels in brain and plasma of guinea pigs. Psychiatry Res 1987;20(4):313–6. doi: 10.1016/0165-1781(87)90092-8
  • Saran A, Addy O, Foliart RH, Schubert DS, Halaris A. Electroencephalographic changes and other indices of neurotoxicity with haloperidol-lithium therapy. Neuropsychobiology 1989;20(3):152–7. doi: 10.1159/000118490
  • Guynn RW, Faillace LA. The effect of the combination of lithium and haloperidol on brain intermediary metabolism in vivo. Psychopharmacology 1979;61:155–9. doi: 10.1007/BF00426730
  • Sawas AH, Gilbert JC. Lipid peroxidation as a possible mechanism for the neurotoxic and nephrotoxic effects of a combination of lithium carbonate and haloperidol. Arch Int Pharmacodyn Ther 1985;276(2):301–12.

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