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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 11, 2008 - Issue 2
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Research article

Delayed CNS maturation in iron-deficient anaemic infants

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Pages 61-68 | Published online: 19 Jul 2013

References

  • Andrews NC. Disorders of iron metabolism. N Engl J Med 1999; 341: 1986–1995.
  • Otero GA, Aguirre DM, Porcayo R, Fernandez T Psychological and electroencephalographic study in school children with iron deficiency. lint JNeurosci 1999; 99: 113–121.
  • Lozoff B, Jimenez E, Hagen J, Mollen E, Wolf AW. Poorer behavioral and developmental outcome more than 10 years after treatment for iron deficiency in infancy. Pediatrics 2000; 105: E51–E62.
  • Grantham-McGregor S, Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr 2001; 131: 649S -668S.
  • Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr 2001; 131: 568S-580S.
  • Beard JL, Connor JR. Iron status and neural functioning. Annu Rev Nutr 2003; 23: 41–58.
  • Akman M, Cebeci D, Okur V, Angyn H, Abaly O, Akman AC. The effects of iron deficiency on infants’ developmental test performance. Acta Paediatr 2004; 93: 1391–1396.
  • Lozoff B, Georgieff MK. Iron deficiency and brain development. Semin Pediatr Neurol 2006; 13: 158–165.
  • Olivares G, Walter K. Consecuencias de la deficiencia de hierro. Revista ChilenaNutr 2003; 30: 226–233.
  • Lozoff B. Iron deficiency and infant development. J Pediatr 1994; 125: 577–578.
  • Lozoff B, Beard J, Connor J, Barbara F, Georgieff M, Schallert T. Long-lasting neural and behavioral effects of iron deficiency in infancy. Nutr Rev 2006; 64: S34–S43.
  • Lozoff B, Jiménez E, Smith JB. Double burden of iron deficiency in infancy and low socioeconomic status: a longitudinal analysis of cognitive test scores to age 19 years. Arch Pediatr Adolesc Med 2006; 160: 1108–1113.
  • Male C, Persson LAE, Freeman V, Guerra A, van’t Hof MA, Haschke F and the Euro-Growth Iron Study Group. Prevalence of iron deficiency in 12-month-old infants from 11 European areas and influence of dietary factors on iron status (Euro-Growth study). Acta Paediatr 2001; 90: 492–498.
  • Rogers SJ, Donovan CM, D’Eugenio D, Brown SL, Whiteside E, Moersch MS, Schafer DS. (eds) Developmental Programming for Infants and Young Children, Vol 2. University of Michigan Press, 1981.
  • John ER, Ahn H, Prichep L, Trepetin M, Brown D, Kave H. Developmental equations for the electroencephalogram. Science 1980; 210: 1255–1258.
  • Moy RJD. Prevalence, consequences and prevention of childhood nutritional iron deficiency: a child public health perspective. Clin Lab Haematol 2006; 28: 291–298.
  • Lozoff B, Wolf AW, Urrutia JJ, Viteri FE. Abnormal behavior and low developmental test scores in iron-deficient anemic infants. J Dev Behav Pediatr 1985; 6: 69–75.
  • Lozoff B, Jimenez E, Wolf AW. Long-term developmental outcome of infants with iron deficiency. N Engl J Med1991; 325: 687–694.
  • Lozoff B, Klein NK, Nelson EC, McClish DK Manuel M, Chacon ME. Behavior of infants with iron-deficiency anemia. Child Dev 1998; 69: 24–36.
  • Corapci F, Radan AE, Lozoff B. Iron deficiency in infancy and mother-child interaction at 5 years. J Dev Behav Pediatr 2006; 7: 371–378.
  • Davies KJ, Maguirre JJ, Brooks GA, Dallman PR, Packer L. Muscle mitochondrial bioenergetics, oxygen supply, and work capacity during dietary iron deficiency and repletion. Am J Physiol 1982; 242: E418–E427.
  • DeUngria M, Rao R, Wobken JD, Luciana M, Nelson CA, Georgieff MK. Perinatal iron deficiency decreases cytochrome c oxidase (CytOx) activity in selected regions of neonatal rat brain. Pediatr Res 2000; 48: 169–176.
  • Goodwill KE, Sabatier C, Stevens RC. Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the protein-binding site. Biochemistry 1998; 37: 13437–13445.
  • Lozoff B, Brittenham GM, Wolf AW, et al. Iron deficiency anemia and iron therapy: effects on infant developmental test performance. Pediatrics 1987; 79: 981–995.
  • Walter T, De Andraca I, Chadud P, Perales CG. Iron deficiency anemia: adverse effects on infant psychomotor development. Pediatrics 1989; 84: 7–17.
  • Berger H. On the electroencephalogram of man. Fifth report. In: Gloor P. (ed) Electroencephalography and clinical neurophysiology (suppl. 28). Amsterdam: Elsevier, 1969; 151–171.
  • Dreyfus-Brisac C. The EEG during the first year of life. In: Lairy GC. (ed) Handbook of electroencephalography and clinical neurophysiology, vol 6B: The evolution of the EEG from birth to adulthood. Amsterdam: Elsevier, 1975; 25–30.
  • Matousek M, Petersen I. Frequency analysis of the EEG in normal children and adolescents. In: Kellaway P, Petersen I. (eds) Automation of clinical electroencephalography. New York: Raven 1973; 75–102.
  • Hagne I, Persson J, Magnusson R, Petersén I. Spectral analysis via fast Fourier transform of waking EEG in normal infants. In: Kellaway P, Petersen I. (eds) Automation of clinical electroencephalography. New York: Raven, 1973; 103–143.
  • Harmony T, Marosi E, Diaz de Leon AE, Becker J, Fernandez T. Effect of sex, psychosocial disadvantages and biological risk factors on EEG maturation. Electroencephalogr Clin Neurophysiol 1990; 75: 482–491.
  • Clarke AR, Barry RJ, McCarthy R, Selikowitz M. Age and sex effects in the EEG development of the normal child. Clin Neurophysiol 2001; 112: 806–814.
  • Peirano P, Algarin C, Garrido M, Algarin D, Lozoff B. Iron-deficiency anemia is associated with altered characteristics of sleep spindles in NREM sleep in infancy. Neurochem Res 2007; 32: 1665–1672.

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