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HEMATOLOGICAL MALIGNANCY

Acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2): Clinical and biological features and comparison with other acute myeloid leukemias with cytogenetic aberrations involving long arm of chromosome 3

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References

  • Jenkins RB, Tefferi A, Solberg LA, Dewald GW. Acute leukemia with abnormal thrombopoiesis and inversions of chromosome 3. Cancer Genet Cytogenet. 1989;39:167–79.
  • Jotterand M, Parlier V, Mühlematter D, Grob JP, Beris Ph. Three new cases of chromosome 3 rearrangement in bands q21 and q26 with abnormal thrombopoiesis bring further evidence to the existence of a 3q21q26 syndrome. Cancer Genet Cytogenet. 1992;59:138–60.
  • Fonatsch C, Gudat H, Lengfelder E, Wandt H, Silling-Engelhardt G, Ludwig WD, et al. Correlation of cytogenetic findings with clinical features in 18 patients with inv(3)(q21q26) or t(3;3)(q21;q26). Leukemia 1994;8:1318–26.
  • Swerdlow SH, Campo E, Lee Harris N, Jaffe ES, Pileri SA, Stein H, et al. WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon: IARC press; 2008.
  • Levy ER, Parganas E, Morishita K, Fichelson S, James L, Oscier D, Gisselbrecht S, Ihle JN, Bucle VJ. DNA rearrangements proximal to the EVI 1 locus associated with the 3q21q26 syndrome. Blood 1994;83:1348–54.
  • Martinelli G, Ottaviani E, Buonamici S, Isidori A, Borsaru G, Visani G, et al. Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts. Haematologica 2003;88:1221–8.
  • Barjesteh van Waalwijk van Doorn-Khosrovani S, Erpelinck C, van Putten WL, Valk PJ, van der Poel-van de Luytgaarde S, Hack R, et al. High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients. Blood 2003;101:837–45.
  • Rogers HJ, Vardiman JW, Anastasi J, Raca G, Savage NM, Cherry AM, et al. Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3)(q21;q26.2): a Bone Marrow Pathology Group study. Haematologica 2014;99:821–9.
  • Cui W, Sun J, Cotta CV, Medeiros J, Lin P. Myelodysplastic syndrome with inv(3)(q21q26.2) or t(3;3)(q21;q26.2) has a high risk for progression to acute myeloid leukemia. Am J Clin Pathol. 2011;136:282–8.
  • Testoni N, Borsaru G, Martinelli G, Carboni C, Ruggeri D, Ottaviani E, et al. 3q21 and 3q26 cytogenetic abnormalities in acute myeloblastic leukemia: biological and clinical features. Haematologica 1999;84:690–4.
  • Weisser M, Haferlach C, Haferlach T, Schnittger S. Advances age and high initial WBC influence the outcome of inv(3)(q21q26)/t(3;3)(q21;q26) positive AML. Leuk Lymphoma 2007;48:2145–51.
  • Medeiros BC, Kohrt HE, Arber DA, Bangs Cd, Cherry AM, Majeti R, Kogel KE, Azar CA, Patel S, Alizadeh AA. Inmunophenotypic features of acute myeloid leukaemia with inv(3)(q21q26.2)/t(3;3)(q21q26.2). Leuk Res. 2010;34:594–7.
  • Lugthart S, Gröschel S, Beverloo HB, Kayser S, Valk P, van Zelderen-Bhola SL, et al. Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia. J Clin Oncol. 2010;28:3890–98.
  • Grimwade D, Hills RK, Moorman AV, Walker H, Chatters S, Goldstone AH, et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood 2010;116:354–65.
  • Haimi M, Elhasid R, Moustafa N, Gershoni-Baruch R. Aberration of 3q and monosomy 7 in a child with acute myelogenous leukemia. Cancer Genet Cytogenet. 2007;174:78–81.
  • Sun J, Konoplev SN, Wang X, Cui W, Chen SS, Medeiros LJ, et al. De novo acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2): a clinicopathologic and cytogenetic study of an entity recently added to the WHO classification. Mod Pathol. 2011;24:384–9.
  • Chung HJ, Seo EJ, Kim KH, Jang S, Park CJ, Lee HJ, et al. Hematologic and clinical features of 3q21q26 syndrome: extremely poor prognosis and association with central diabetes insipidus. Korean J Lab Med. 2007;27:133–8.
  • Reiter E, Greinix H, Rabitsch W, Keil F, Schwarzinger I, Jaeger U, et al. Low curative potential of bone marrow transplantation for highly aggressive acute myelogenous leukemia with inversion inv (3)(q21q26) or homologous translocation t(3;3)(q21q26). Ann Hematol. 2000;79:374–7.
  • Horsman DE, Gascoyne RD, Barnett MJ. Acute leukaemia with structural rearrangements of chromosome 3. Leuk Lymphoma 1995;16:369–77.
  • Lim G, Kim MJ, Oh SH, Cho SY, Lee HJ, Suh JT, et al. Acute myeloid leukemia associated with t(1;3)(p36;q21) and extreme thrombocytosis: a clinical study with literature review. Cancer Genet Cytogenet. 2010;203:187–92.
  • Granada I, Luño E, Ribera JM, Sanzo C, Sancho JM, Muñiz SG, et al. Translocation (3;10)(q26;q22): a new nonrandom abnormality in three patients with 3q26 Involvement. Cancer Genet Cytogenet. 2000;121:99–100.
  • Yamamoto K, Nagata K, Tsurukubo Y, Morishita K, Hamaguchi H. A novel translocation t(3;22)(q21;q11) involving 3q21 in myelodysplastic syndrome-derived overt leukemia with thrombocytosis. Leuk Res. 2000;24:435–57.
  • Chang VT, Aviv H, Howard LM, Padberg F. Acute myelogenous leukemia associated with extreme symptomatic thrombocytosis and chromosome 3q translocation: case report and review of literature. Am J Hematol. 2003;72:20–26.
  • Yamagata N, Shimazaki C, Kikuta T, Hirai H, Sumikuma T, Sudo Y, et al. A translocation between 3q21 and 12q24 in a patient with minimally differentiated acute myeloidleukemia (AML-M0). Cancer Genet Cytogenet. 1997;97:90–93.
  • Li S, Yin C, Medeiros J, Bueso-Ramos C, Lu G, Lin P. Myelodysplastic syndrome/acute myeloid leukemia with t(3;21)(q26.2;q22) is commonly a therapy-related disease associated with poor outcome. Am J Clin Pathol. 2012;138:146–52.

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