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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 34, 2012 - Issue 3
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Original Article

The alterations of inducible nitric oxide synthase in the mouse brainstem during herpes simplex virus type 1-induced facial palsy

Yanyan Mao Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University; Shandong Provincial Key Laboratory of Otology
,
Zhaomin Fan Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University
,
Yuechen Han Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University
,
Wenwen Liu Shandong Provincial Key Laboratory of Otology
,
Lei Xu Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University
,
Zhen Jiang Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University
,
Jianfeng Li Shandong Provincial Key Laboratory of Otology; Institute of Eye and ENTProvincial Hospital affiliated to Shandong University, Jinan, China
&
Haibo Wang Otolaryngology–Head and Neck SurgeryProvincial Hospital Affiliated to Shandong University; Shandong Provincial Key Laboratory of Otology; Institute of Eye and ENTProvincial Hospital affiliated to Shandong University, Jinan, ChinaCorrespondence[email protected]
 show all
Pages 304-313 | Published online: 12 Nov 2013

References

  • Ahmed A. When is facial paralysis Bell palsy? Current diagnosis and treatment. Cleve Clin J Med. 2005;72:398–401, 405.
  • Kennedy PGE. Herpes simplex virus type 1 and Bell’s palsy — a current assessment of the controversy. J Neurovirol. 2010;16:1–5.
  • Holland NJ, Weiner GM. Recent developments in Bell’s palsy. BMJ. 2004;329:553–7.
  • Schirm J, Mulkens PS. Bell’s palsy and herpes simplex virus. APMIS. 1997;105:815–23.
  • Sugita T, Murakami S, Yanagihara N, Fujiwara Y, Hirata Y, Kurata T. Facial nerve paralysis induced by herpes simplex virus in mice: an animal model of acute and transient facial paralysis. Ann Otol Rhinol Laryngol. 1995;104:574–81.
  • Takahashi H, Hato N, Honda N, Kisaki H, Wakisaka H, Matsumoto S, et al.. Effects of acyclovir on facial nerve paralysis induced by herpes simplex virus type 1 in mice. Auris Nasus Larynx. 2003;30:1–5.
  • Fiallos-Estrada CE, Kummer W, Mayer B, Bravo R, Zimmermann M. Long-lasting increase of nitric oxide synthase immunoreactivity, NADPH-diaphorase reaction and c-JUN co-expression in rat dorsal root ganglion neurons following sciatic nerve transection. Neurosci Lett. 1993;150:169–73.
  • Yu WH. Nitric oxide synthase in motor neurons after axotomy. J Histochem Cytochem. 1994;42:451–7.
  • Knott AB, Bossy-Wetzel E. Nitric oxide in health and disease of the nervous system. Antioxid Redox Signal. 2009;11:541–54.
  • Marques CP, Cheeran MC, Palmquist JM, Hu S, Lokensgard JR. Microglia are the major cellular source of inducible nitric oxide synthase during experimental herpes encephalitis. J Neurovirol. 2008;14:229–38.
  • Fujii S, Akaike T, Maeda H. Role of nitric oxide in pathogenesis of herpes simplex virus encephalitis in rats. Virology. 1999;256:203–12.
  • Meyding-Lamade U, Seyfer S, Haas J, Dvorak F, Kehm R, Lamadé W, et al.. Experimental herpes simplex virus encephalitis: inhibition of the expression of inducible nitric oxide synthase in mouse brain tissue. Neurosci Lett. 2002;318:21–4.
  • Gonzalez-Hernandez T, Rustioni A. Expression of three forms of nitric oxide synthase in peripheral nerve regeneration. J Neurosci Res. 1999;55:198–207.
  • Chen K, Northington FJ, Martin LJ. Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice. Brain Struct Funct. 2010;214:219–34.
  • Chikawa T, Ikata T, Katoh S, Hamada Y, Kogure K, Fukuzawa K. Preventive effects of lecithinized superoxide dismutase and methylprednisolone on spinal cord injury in rats: transcriptional regulation of inflammatory and neurotrophic genes. J Neurotrauma. 2001;18:93–103.
  • Wang HB, Feng HY, Fan ZM, Xu L, Wang LJ. Experimental study of the facial nerve paralysis induced by herpes simplex virus type 1 infection in mice. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2006;41:13–6. Chinese.
  • Takahashi H, Hitsumoto Y, Honda N, Hato N, Mizobuchi M, Murakami S, et al.. Mouse model of Bell’s palsy induced by reactivation of herpes simplex virus type 1. J Neuropathol Exp Neurol. 2001;60:621–7.
  • Lokensgard JR, Hu S, Sheng W, vanOijen M, Cox D, Cheeran MC, et al.. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J Neurovirol. 2001;7:208–19.
  • Lopez-Figueroa MO, Day HE, Lee S, Rivier C, Akil H, Watson SJ. Temporal and anatomical distribution of nitric oxide synthase mRNA expression and nitric oxide production during central nervous system inflammation. Brain Res. 2000;852:239–46.
  • Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci. 2007;8:57–69.
  • Akaike T, Suga M, Maeda H. Free radicals in viral pathogenesis: molecular mechanisms involving superoxide and NO. Proc Soc Exp Biol Med. 1998;217:64–73.
  • Heneka MT, Klockgether T, Feinstein DL. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. J Neurosci. 2000;20:6862–7.
  • Golde S, Coles A, Lindquist JA, Compston A. Decreased iNOS synthesis mediates dexamethasone-induced protection of neurons from inflammatory injury in vitro. Eur J Neurosci. 2003;18:2527–37.
  • Olanow C. A radical hypothesis for neurodegeneration. Trends Neurosci. 1993;16:439–444.
  • Matsumura M, Kakishita H, Suzuki M, Banba N, Hattori Y. Dexamethasone suppresses iNOS gene expression by inhibiting NF-[kappa] B in vascular smooth muscle cells. Life Sci. 2001;69:1067–77.

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