Advanced search
Publication Cover
Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 35, 2013 - Issue 6
Submit an article Journal homepage
80
Views
11
CrossRef citations to date
0
Altmetric
Original Articles

In vivo monitoring of arterially transplanted bone marrow mononuclear cells in a rat transient focal brain ischemia model using magnetic resonance imaging

Nobuo Kamiya Department of NeurologyNippon Medical School, Tokyo, JapanCorrespondence[email protected]
,
Masayuki Ueda Department of NeurologyNippon Medical School, Tokyo, Japan
,
Hironaka Igarashi Center for Integrated Human Brain ScienceUniversity of Niigata, Japan
,
Yasuhiro Nishiyama Department of NeurologyNippon Medical School, Tokyo, Japan
,
Satoshi Suda Department of NeurologyNippon Medical School, Tokyo, Japan
,
Seiji Okubo Department of NeurologyNippon Medical School, Tokyo, Japan
,
Toshiki Inaba Department of NeurologyNippon Medical School, Tokyo, Japan
&
Yasuo Katayama Department of NeurologyNippon Medical School, Tokyo, Japan
 show all
Pages 573-579 | Published online: 05 Dec 2013

References

  • Iihoshi S, Honmou O, Houkin K, Hashi K, Kocsis JD. A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats. Brain Res. 2004;1007:1–9.
  • Brenneman M, Sharma S, Harting M, Strong R, Cox CS, Aronowski J, et al.. Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab. 2010;30:140–9.
  • Yang B, Strong R, Sharma S, Brenneman M, Mallikarjunarao K, Xi X, et al.. Therapeutic time window and dose response of autologous bone marrow mononuclear cells for ischemic stroke. J Neurosci Res. 2011;89:833–9.
  • Kamiya N, Ueda M, Igarashi H, Nishiyama Y, Suda S, Inaba T, et al.. Intra-arterial transplantation of bone marrow mononuclear cells immediately after reperfusion decreases brain injury after focal ischemia in rats. Life Sci. 2008;83:433–7.
  • Chopp M, Li Y. Treatment of neural injury with marrow stromal cells. Lancet Neurol. 2002;1:92–100.
  • Crigler L, Robey RC, Asawachaicharn A, Gaupp D, Phinney DG. Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis. Exp Neurol. 2006;198:54–64.
  • Keimpema E, Fokkens MR, Nagy Z, Agoston V, Luiten PG, Nyakas C, et al.. Early transient presence of implanted bone marrow stem cells reduces lesion size after cerebral ischaemia in adult rats. Neuropathol Appl Neurobiol. 2009;35:89–102.
  • Walczak P, Zhang J, Gilad AA, Kedziorek DA, Ruiz-Cabello J, Young RG, et al.. Dual-modality monitoring of targeted intraarterial delivery of mesenchymal stem cells after transient ischemia. Stroke. 2008;39:1569–74.
  • Stroh A, Zimmer C, Werner N, Gertz K, Weir K, Kronenberg G, et al.. Tracking of systemically administered mononuclear cells in the ischemic brain by high-field magnetic resonance imaging. Neuroimage. 2006;33:886–97.
  • Jendelova P, Herynek V, DeCroos J, Glogarová K, Andersson B, Hájek M, et al.. Imaging the fate of implanted bone marrow stromal cells labeled with superparamagnetic nanoparticles. Magn Reson Med. 2003;50:767–76.
  • Walczak P, Kedziorek DA, Gilad AA, Lin S, Bulte JW. Instant MR labeling of stem cells using magnetoelectroporation. Magn Reson Med. 2005;54:769–74.
  • Messina LM, Podrazik RM, Whitehill TA, Ekhterae D, Brothers TE, Wilson JM, et al.. Adhesion and incorporation of lacZ-transduced endothelial cells into the intact capillary wall in the rat. Proc Natl Acad Sci USA. 1992;89:12018–22.
  • Kurozumi K, Nakamura K, Tamiya T, Kawano Y, Ishii K, Kobune M, et al.. Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model. Mol Ther. 2005;11:96–104.
  • Li L, Jiang Q, Qu CS, Ding GL, Li QJ, Wang SY, et al.. Transplantation of marrow stromal cells restores cerebral blood flow and reduces cerebral atrophy in rats with traumatic brain injury: in vivo MRI study. J Neurotrauma. 2011;28:535–45.
  • Modo M, Cash D, Mellodew K, Williams SC, Fraser SE, Meade TJ, et al.. Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. Neuroimage. 2002;17:803–11.
  • Li L, Jiang Q, Ding G, Zhang L, Zhang ZG, Li Q, et al.. Effects of administration route on migration and distribution of neural progenitor cells transplanted into rats with focal cerebral ischemia, an MRI study. J Cereb Blood Flow Metab. 2010;30:653–62.
  • Yano S, Kuroda S, Shichinohe H, Hida K, Iwasaki Y. Do bone marrow stromal cells proliferate after transplantation into mice cerebral infarct? — a double labeling study. Brain Res. 2005;1065:60–7.
  • Vasconcelos-dos-Santos A, Rosado-de-Castro PH, Lopes de Souza SA, da Costa Silva J, Ramos AB, Rodriguez de Freitas G, et al.. Intravenous and intra-arterial administration of bone marrow mononuclear cells after focal cerebral ischemia: is there a difference in biodistribution and efficacy? Stem Cell Res. 2012;9:1–8.
  • Barbosa da Fonseca LM, Gutfilen B, Rosado de Castro PH, Battistella V, Goldenberg RC, Kasai-Brunswick T, et al.. Migration and homing of bone-marrow mononuclear cells in chronic ischemic stroke after intra-arterial injection. Exp Neurol. 2010;221:122–8.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.