Acetamides: chemotherapeutic agents for inflammation-associated cancers

References

• Balkwill F , Mantovani A . Inflammation and cancer: back to Virchow? Lancet. 2001;357:539–45.
   PubMed Web of Science ®Google Scholar
• Karin M . Nuclear factor-kappaB in cancer development and progression. Nature. 2006;441:431–6.
   PubMed Web of Science ®Google Scholar
• Mantovani A , Allavena P , Sica A , Balkwill F . Cancer-related inflammation. Nature. 2008;454:436–44.
   PubMed Web of Science ®Google Scholar
• Aggarwal BB , Vijayalekshmi RV , Sung B . Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, longterm foe. Clin Cancer Res. 2009;15:425–30.
   PubMed Web of Science ®Google Scholar
• de Martel C , Franceschi S . Infections and cancer: established associations and new hypotheses. Crit Rev Oncol Hematol. 2009;70:183–94.
   PubMed Web of Science ®Google Scholar
• Takahashi H , Ogata H , Nishigaki R , Broide DH , Karin M . Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta and JNK1-dependent inflammation. Cancer Cell. 2010;17:89–97.
   PubMed Web of Science ®Google Scholar
• Khasawneh J , Schulz MD , Walch A , Rozman J , Hrabe de Angelis M , Klingenspor M , et al. Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion. Proc Natl Acad Sci USA. 2009;106:3354–9.
   PubMed Web of Science ®Google Scholar
• Park EJ , Lee JH , Yu GY , He G , Ali SR , Holzer RG , et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell. 2010;140:197–208.
   PubMed Web of Science ®Google Scholar
• Rani P , Pal D , Hegde RR , Hashim SR . Anticancer, anti-inflammatory, and analgesic activities of synthesized 2-(substituted phenoxy) acetamide derivatives. Biomed Res Int. 2014;2014:386473.
   PubMed Web of Science ®Google Scholar
• Rani P , Pal D , Hegde RR , Hashim SR . Synthesis, characterization and pharmacological evaluation of substituted phenoxy acetamide derivatives. Hemijska industrija. 2014;Online-First(00):57.
   Google Scholar
• Marjanović M , Zorc B , Pejnović L , Zovko M , Kralj M . Fenoprofen and ketoprofen amides as potential antitumor agents. Chem Biol Drug Des. 2007;69:222–6.
   PubMed Web of Science ®Google Scholar
• Raghavendra NM , Jyothsna A , Rao AV , Subrahmanyam CVS . Synthesis, pharmacological evaluation and docking studies of N-(benzo[d]thiazol-2-yl)-2-(piperazin-1-yl)acetamide analogs as COX-2 inhibitors. Bioorg Med Chem Lett. 2012;22:820–3.
   PubMed Web of Science ®Google Scholar
• Ang W , Lin YN , Yang T , Yang JZ , Pi WY , Yang YH , et al. Synthesis and biological evaluation of 2-(3-fluoro-4-nitro phenoxy)-N-phenylacetamide derivatives as novel potential affordable antitubercular agents. Molecules. 2012;17(2):2248–4458.
   PubMed Web of Science ®Google Scholar
• Nikalje APG , Choudhari S , Une H . Design, synthesis and hypoglycemic activity of novel 2-(4-((2, 4-dioxothiazolidin-5-ylidene) methyl)-2-methoxyphenoxy)-N- substituted acetamide derivatives. Eur J Exp Biol. 2012;2:1302–14.
   Google Scholar
• Kumar S , Wahi AK , Singh R . Synthesis and preliminary pharmacological evaluation of 2-[4-(Aryl substituted) piperazin-1-yl]-Nphenylacetamides: potential antipsychotics. Trop J Pharm Res. 2011;10:265–72.
   Web of Science ®Google Scholar
• Tipparaju SK , Muench SP , Mui EJ , Ruzheinikov SN , Lu JZ , Hutson SL , et al. Identification and development of novel inhibitors of toxoplasma gondii enoyl reductase. J Med Chem. 2010;53:6287–300.
   PubMed Web of Science ®Google Scholar
• Hedstrom LK , Striepen B , IMP dehydrogenase inhibitors for treating mammalian gastrointestinal parasitic infections. 2007;WO143557:2007.
   Google Scholar
• Pal D , Banerjee S , Ghosh AK . Dietary-induced cancer prevention: an expanding research arena of emerging diet related to healthcare system. J Adv Pharm Tech Res. 2012;3(1):16–24.
   PubMedGoogle Scholar
• Pal D , Mitra S . A preliminary study on the in vitro antioxidant activity of the stems of Opuntia vulgaris. J Adv Pharm Tech Res. 2010;1(2):268–72.
   PubMedGoogle Scholar
• Nayak AK , Pal D , Pany DR , Mohanty B . Evaluation of Spinacia oleracea L. leavesmucilage as an innovative suspending agent. J Adv Pharm Tech Res. 2010;1(3):338–41.
   PubMedGoogle Scholar
• Jayadevappa HP , Nagendrappa G , Umesha S , Chandrashekar S . Synthesis and antimicrobial study of N-[4-(2-piperidine-1-yl-ethoxy) phenyl] acetamide analogues. J Adv Pharm Tech Res. 2012;02:192–6.
   Google Scholar
• World Cancer Research Fund/American Institute for Cancer Research . Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington, DC: AICR; 2007.
   Google Scholar
• Gremy F , Momas I , Daures JP . Risk factors in bladder cancer. A case-control study in the department of Herault, France. Bull Acad Natl Med. 1993;177:47–62.
   PubMed Web of Science ®Google Scholar
• Geoffroy-Perez B , Cordier S . Fluid consumption and the risk of bladder cancer: results of a multicenter casecontrol study. Int J Cancer. 2001;93:880–7.
   PubMed Web of Science ®Google Scholar
• Blaser MJ , Chyou PH , Nomura A . Age at establishment of Helicobacter pylori infection and gastric carcinoma, gastric ulcer, and duodenal ulcer risk. Cancer Res. 1995;55:562–5.
   PubMed Web of Science ®Google Scholar
• Scholl SM , Pallud C , Beuvon F , Hacene K , Stanley ER , Rohrschneider L , et al. Anti-colonystimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. J Natl Cancer Inst. 1994;86:120–6.
   PubMedGoogle Scholar
• Shacter E , Weitzman SA . Chronic inflammation and cancer. Oncology. 2002;16:217–26.
   PubMed Web of Science ®Google Scholar
• Kuper H , Adami HO , Trichopoulos D . Infections as a major preventable cause of human cancer. J Intern Med. 2000;248:171–83.
   PubMed Web of Science ®Google Scholar
• Lorusso G , Rüegg C . The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol. 2008;130:1091–103.
   PubMed Web of Science ®Google Scholar
• Philip M , Rowley DA , Schreiber H . Inflammation as a tumor promoter in cancer induction. Semin Cancer Biol. 2004;14:433–9.
   PubMed Web of Science ®Google Scholar
• Coussens LM , Werb Z . Inflammation and cancer. Nature. 2002;420:860–7.
   PubMed Web of Science ®Google Scholar
• Macarthur M , Hold GL , El-Omar EM . Inflammation and cancer. II. Role of chronic inflammation and cytokine polymorphisms in the pathogenesis of gastrointestinal malignancy. Am J Physiol Gastrointest Liver Physiol. 2004;286:G515–20.
   PubMed Web of Science ®Google Scholar
• Shin HR , Oh JK , Masuyer E , Curado MP , Bouvard V , Fang YY , et al. Epidemiology of cholangiocarcinoma: an update focusing on risk factors. Cancer Sci. 2010;101:579–85.
   PubMed Web of Science ®Google Scholar
• Block TM , Mehta AS , Fimmel CJ , Jordan R . Molecular viral oncology of hepatocellular carcinoma. Oncogene. 2003;22:5093–107.
   PubMed Web of Science ®Google Scholar
• Bhatla N , Joseph E . Cervical cancer prevention & the role of human papillomavirus vaccines in India. Indian J Med Res. 2009;130:334–40.
   PubMed Web of Science ®Google Scholar
• Martró E , Esteve A , Schulz TF , Sheldon J , Gambús G , Muñoz R , et al. Euro-Shaks study group. Risk factors for human Herpesvirus 8 infection and AIDS-associated Kaposi's sarcoma among men who have sex with men in a European multicentre study. Int J Cancer. 2006;120:1129–35.
   Web of Science ®Google Scholar
• Rosin MR , Anwar WA , Ward AJ . Inflammation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res. 1994;54:1929S–33S.
   PubMed Web of Science ®Google Scholar
• Morrison WB . Inflammation and cancer: a comparative view. J Vet Intern Med. 2012;26:18–31.
   PubMed Web of Science ®Google Scholar
• Whitcomb DC . Inflammation and cancer. V. chronic pancreatitis and pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2004;287:G315–9.
   PubMed Web of Science ®Google Scholar
• Palapattu GS , Sutcliffe S , Bastian PJ , Platz EA , De Marzo AM , Isaacs WB , et al. Prostate carcinogenesis and inflammation: emerging insights. Carcinogenesis. 2004;26:1170–81.
   PubMed Web of Science ®Google Scholar
• Perky L . Epidemiology of cancer of the penis. Recent Results Cancer Res. 1977;60:97–109.
   PubMedGoogle Scholar
• Askling J , Grunewald J , Eklund A , Hillerdal G , Ekbom A . Increased risk for cancer following sarcoidosis. Am J Respir Crit Care Med. 1999;160:1668–72.
   PubMed Web of Science ®Google Scholar
• Vesterinen E , Pukkala E , Timonen T , Aromaa A . Cancer incidence among 78,000 asthma patients. Int J Epidemiol. 1993;22:976–82.
   PubMed Web of Science ®Google Scholar
• Alavanja MC , Brownson RC , Boice JD , Hock E . Preexisting lung disease and lung cancer among nonsmoking women. Am J Epidemiol. 1992;136:623–32.
   PubMed Web of Science ®Google Scholar
• Wu AH , Fontham ET , Reynolds P , Greenberg RS , Buffler P , Liff J , et al. Previous lung disease and risk of lung cancer among lifetime nonsmoking women in the United States. Am J Epidemiol. 1995;141:1023–32.
   PubMed Web of Science ®Google Scholar
• Mayron R , Grimwood RE , Siegle RJ , Camisa C . Verrucous carcinoma arising in ulcerative lichen planus of the soles. J Dermatol Surg Oncol. 1988;14:547–51.
   PubMedGoogle Scholar
• Maeda H , Akaike T . Nitric oxide and oxygen radicals in infection, inflammation, and cancer. Biochemistry. 1998;63:854–65.
   PubMed Web of Science ®Google Scholar
• Yamanishi Y , Boyle DL , Rosengren S , Green DR , Zvaifler NJ , Firestein GS . Regional analysis of p53 mutations in rheumatoid arthritis synovium. Proc Natl Acad Sci USA. 2002;99:10025–30.
   PubMed Web of Science ®Google Scholar
• Eaden J , Abrams K , Ekbom A , Jackson E , Mayberry J . Colorectal cancer prevention in ulcerative colitis: a casecontrol study. Aliment Pharmacol Ther. 2000;14:145–53.
   PubMed Web of Science ®Google Scholar
• Itzkowitz SH , Yio X . Inflammation and cancer. IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol. 2004;287:G7–17.
   PubMed Web of Science ®Google Scholar
• Seril DN , Lia J , Yang GY , Yang CS . Oxidative stress and ulcerative colitis associated carcinogenesis: studies in humans and animal models. Carcinogenesis. 2003;24:353–62.
   PubMed Web of Science ®Google Scholar
• Moody GA , Jayanthi V , Probert CS , Mac Kay H , Mayberry JF . Long term therapy with ulphasalazine protects against colorectal cancer in ulcerative colitis; a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol. 1996;8:1179–83.
   PubMed Web of Science ®Google Scholar
• Ernst PB , Gold BD . The disease spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer. Annu Rev Microbiol. 2000;54:615–40.
   PubMed Web of Science ®Google Scholar
• Cordon-Cardo C , Prives C . At the crossroads of inflammation and tumorigenesis. J Exp Med. 1999;190:1367–70.
   PubMed Web of Science ®Google Scholar
• Hudson JD , Shoaibi MA , Maestro R , Carnero A , Hannon GJ , Beach DH . A proinflammatory cytokine inhibits p53 tumor suppressor activity. J Exp Med. 1999;190:1375–82.
   PubMed Web of Science ®Google Scholar
• Becker C , Fantini MC , Schramm C , Lehr HA , Wirtz S , Nikolaev A , et al. TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity. 2004;21:491–501.
   PubMed Web of Science ®Google Scholar
• Tsujii M , Kawano S , Dubois RN . Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci U S A. 1997;94:3336–40.
   PubMed Web of Science ®Google Scholar
• Eberhart CE , Coffey RJ , Radhika A , Giardiello FM , Ferrenbach S , Dubois RN . Upregulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology. 1994;107:1183–8.
   PubMed Web of Science ®Google Scholar
• Hwang D , Scollard D , Byrne J , Levine E . Expression of cyclooxygenase- 1 and cyclooxygenase-2 in human breast cancer. J Natl Cancer Inst. 1998;90:455–60.
   PubMed Web of Science ®Google Scholar
• Hida T , Yatabe Y , Achiwa H , Muramatsu H , Kozaki K , Nakamura S , et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res. 1998;58:3761–4.
   PubMed Web of Science ®Google Scholar
• Mantovani A , Bottazzi B , Colotta F , Sozzani S , Ruco L . The origin and function of tumor-associated macrophages. Immunol Today. 1992;13:265–70.
   PubMedGoogle Scholar
• Mantovani A , Bussolino F , Dejana E . Cytokine regulation of endothelial cell function. FASEB J. 1992;6:2591–9.
   PubMed Web of Science ®Google Scholar
• Coussens LM , Tinkle CL , Hanahan D , Werb Z . MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell. 2000;103:481–90.
   PubMed Web of Science ®Google Scholar
• van den Berg A , Visser L , Poppema S . High expression of the CC chemokine TARC in Reed-Sternberg cells: a possible explanation for the characteristic T-cell infiltrate in Hodgkin's lymphoma. Am J Pathol. 1999;154:1685–91.
   PubMed Web of Science ®Google Scholar
• Burke F , Relf M , Negus R , Balkwill F . A cytokine profile of normal and malignant ovary. Cytokine. 1996;8:578–85.
   PubMed Web of Science ®Google Scholar
• Naylor MS , Stamp GWH , Foulkes WD , Eccles D , Balkwill FR . Tumor necrosis factor and its receptors in human ovarian cancer. J Clin Invest. 1993;91:2194–206.
   PubMed Web of Science ®Google Scholar
• Hemasrilatha S , Sruthi K , Manjula A , Harinadha Babu V , Vittal Rao B . Synthesis and antiinflammatory activity of imidazo[1,2-a]pyridinyl/pyrazinyl benzamides and acetamides. Indian J Chem Sect B. 2012;51B:981–7.
   Google Scholar
• Amir M , Saifullah K , Akhter W . Design, synthesis and pharmacological evaluation of 1,3,4-oxadizole derivatives of aryl acetic acid as anti-inflammatory and analgesic agents. Indian J Chem Sect B. 2011;50B(8):1107–11.
   Google Scholar
• Dogruer DS , Kupeli E , Yesilada E , Fethi Sahin M . Synthesis of New 2-[1(2H)-Phthalazinon-2- yl]acetamide and 3-[1(2H)-Phthalazinon-2-yl]propanamide derivatives as antinociceptive and antiinflammatory Agents. Archiv der Pharmazie. 2004;337(6):303–10.
   PubMed Web of Science ®Google Scholar
• Mahdi MF , Mohammed MH , Jassim AA . Design, synthesis and preliminary pharmacological evaluation of new non-steroidal anti-inflammatory agents having a 4-(Methylsulfonyl) aniline pharmacophore. Molecules. 2012;17:1751–63.
   PubMed Web of Science ®Google Scholar
• Priyanka , Gautam MK , Sharma NK , Jha KK , Vijayakumar M . Design, synthesis and pharmacological screening of 2-(2-(benzo[d]oxazol-2-yl)phenylamino)-N-(substituted phenyl)acetamides as anti-inflammatory and analgesic agents. JASR. 2014;5(1):22–7.
   Google Scholar
• Fernandes J , Kumar P , Kumar A . Synthesis of some novel oxazolidinones having benzo thiazinen derivatives as antimicrobial and anti-inflammatory agents. Int J Pharm Sci Drug Res. 2013;5(3):101–4.
   Google Scholar
• Obafemi CA , Taiwo FO , Iwalewa EO , Akinpelu DA . Synthesis, antibacterial and anti-inflammatory activities of some 2-phenylglyoxylic acid derivatives. Int J Life Sci Pharma Res. 2012;2(2):22–36.
   Google Scholar
• Sun A , Prussia A , Zhan W , Murray EE , Doyle J , Cheng LT , et al. Nonpeptide inhibitors of measles virus entry. J Med Chem. 2006;49:5080–92.
   PubMed Web of Science ®Google Scholar
• Aliabadi A , Andisheh S , Tayarani-Najaran Z , Tayarani-Najaran M . 2-(4-Fluorophenyl)-Nphenylacetamide derivatives as anticancer agents: synthesis and in-vitro cytotoxicity evaluation. Iran J Pharm Res. 2013;12:267–71.
   PubMed Web of Science ®Google Scholar
• Lee K , Roh SH , Xia Y , Kan KW . Synthesis and biological evaluation of phenoxy-N-phenylacetamide derivatives as novel P-glycoprotein inhibitors. Bull Korean Chem Soc. 2011;32:3666–74.
   Web of Science ®Google Scholar
• Xiang P , Zhou T , Wang L , Sun CY , Hu J , Zhao YL , et al. Novel benzothiazole, benzimidazole and benzoxazole derivatives as potential antitumor agents: synthesis and preliminary in vitro biological evaluation. Molecules. 2012;17:873–83.
   PubMed Web of Science ®Google Scholar
• Autore G , Caruso A , Marzocco S , Nicolaus B , Palladino C , Pinto A , et al. Acetamide derivatives with antioxidant activity and potential anti-inflammatory activity. Molecules. 2010;15:2028–38.
   PubMed Web of Science ®Google Scholar
• Herbert JM , Woodgate PD , Denny WA . Potential antitumor agents. 53. Synthesis, DNA binding properties, and biological activity of perimidenes designed as minimal DNA-intercalacting. Agents J Med Chem. 1987;30:2081–6.
   PubMed Web of Science ®Google Scholar
• Shi XH , Wang Z , Xia Y , Ye TH , Deng M , Xu YZ , et al. Synthesis and biological evaluation of novel benzothiazole-2-thiol derivatives as potential anticancer agents. Molecules. 2012;17:3933–44.
   PubMed Web of Science ®Google Scholar
• Chiou CT , Lee WC , Liao JH , Cheng JJ , Lin LC , Chen CY , et al. Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents. Eur J Med Chem. 2015;98:1–12.
   PubMed Web of Science ®Google Scholar
• Said M , Elshihawy H . Synthesis, anticancer activity and structure-activity relationship of some anticancer agents based on Cyclopenta (b) thiophene scaffold. Pak J Pharm Sci. 2014;27(4):885–92.
   PubMed Web of Science ®Google Scholar
• Akgul O , Tarikogullari AH , Kose FA , Kirmizibayrak PB , Pabuccuoglu MV . Synthesis and cytotoxic activity of some 2-(2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetamide derivatives. Turk J Chem. 2013;37:204–12.
   Web of Science ®Google Scholar
• Uddin MJ , Crews BC , Blobaum AL , Kingsley PJ , Ghebreselasie K , Saleh SS , et al. Synthesis and evaluation of indomethacin derivatives as COX-2 targeted imaging agents. J Labelled Compd Radiopharm. 2009;52:387–93.
   Web of Science ®Google Scholar
• Nayak PS , Narayana B , Sarojini BK , Hedge K , Shashidhara KS . Design and synthesis of novel heterocyclic acetamide derivatives for potential analgesic, anti-inflammatory, and antimicrobial activities. Med Chem Res. 2014;23:4280–94.
   Web of Science ®Google Scholar
• Kalgutkar AS , Crews BC , Saleh S , Prudhomme D , Marnett LJ . Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors. Bioorg Med Chem. 2005;13:6810–22.
   PubMed Web of Science ®Google Scholar
• Kalgutkar AS , Marnett AB , Crews BC , Remmel RP , Marnett LJ . Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. J Med Chem. 2000;43:2860–70.
   PubMed Web of Science ®Google Scholar
• Baron JA , Sandler RS . Nonsteroidal anti-inflammatory drugs and cancer prevention. Annu Rev Med. 2000;51:511–23.
   PubMed Web of Science ®Google Scholar
• García-Rodríguez LA , Huerta-Alvarez C . Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugs. Epidemiology. 2001;12:88–93.
   PubMed Web of Science ®Google Scholar
• Williams CS , Mann M , DuBois RN . The role of cyclooxygenases in inflammation, cancer, and development. Oncogene. 1999;18:7908–16.
   PubMed Web of Science ®Google Scholar
• Tannock IF , de Wit R , Berry WR , Horti J , Pluzanska A , Chi KN , et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med. 2004;351:1502–12.
   PubMed Web of Science ®Google Scholar
• Venkitaraman R , Thomas K , Huddart RA , Horwich A , Dearnaley DP , Parker CC . Efficacy of low-dose dexamethasone in castration-refractory prostate cancer. BJU Int. 2008;101:440–3.
   PubMed Web of Science ®Google Scholar
• Adams GP , Weiner LM . Monoclonal antibody therapy of cancer. Nat Biotechnol. 2005;23:1147–57.
   PubMed Web of Science ®Google Scholar
• Eisen T , Boshoff C , Mak I , Sapunar F , Vaughan MM , Pyle L , et al. Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer. Br J Cancer. 2000;82:812–7.
   PubMed Web of Science ®Google Scholar
• Madhusudan S , Foster M , Muthuramalingam SR , Braybrooke JP , Wilner S , Kaur K , et al. A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer. Clin Cancer Res. 2004;10:6528–34.
   PubMed Web of Science ®Google Scholar
• Orlowski RZ , Kuhn DJ . Proteasome inhibitors in cancer therapy: lessons from the first decade. Clin Cancer Res. 2008;14:1649–57.
   PubMed Web of Science ®Google Scholar
• Singh S , Khar A . Biological effects of curcumin and its role in cancer chemoprevention and therapy. Anticancer Agents Med Chem. 2006;6:259–70.
   PubMedGoogle Scholar
• Hawkey CJ . Cox-2 inhibitors. Lancet. 1999;353:307–14.
   PubMed Web of Science ®Google Scholar
• Lanzo CA , Beechem JM , Talley J , Marnett LJ . Investigation of the binding of isoform-selective inhibitors to prostaglandin endoperoxide syntheses using fluorescence spectroscopy. Biochemistry. 1998;37:217–26.
   PubMed Web of Science ®Google Scholar