225
Views
76
CrossRef citations to date
0
Altmetric
Research Articles

Age-related prevalence of low testosterone in men with spinal cord injury

, &

References

  • Gray A, Feldman HA, McKinlay JB, Longcope C. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J Clin Endocrinol Metab 1991;73(5):1016–25.
  • Longcope C, Goldfield SR, Brambilla DJ, McKinlay J. Androgens, estrogens, and sex hormone-binding globulin in middle-aged men. J Clin Endocrinol Metab 1990;71(6):1442–6.
  • Simon D, Preziosi P, Barrett-Connor E, Roger M, Saint-Paul M, Nahoul K, et al. The influence of aging on plasma sex hormones in men: the Telecom Study. Am J Epidemiol 1992;135(7):783–91.
  • Harman SM, Metter EJ, Tobin JD, Pearson J, Blackman MR. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 2001;86(2):724–31.
  • Morley JE, Kaiser FE, Perry HM, III, Patrick P, Morley PM, Stauber PM, et al. Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men. Metabolism 1997;46(4):410–3.
  • Zmuda JM, Cauley JA, Kriska A, Glynn NW, Gutai JP, Kuller LH. Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants. Am J Epidemiol 1997;146(8):609–17.
  • Vermeulen A, Kaufman JM. Ageing of the hypothalamo-pituitary-testicular axis in men. Horm Res 1995;43(1–3):25–8.
  • Tenover JL. Testosterone and the aging male. J Androl 1997;18(2):103–6.
  • Reddy RG, Aung T, Karavitaki N, Wass JA. Opioid induced hypogonadism. BMJ 2010;341:c4462.
  • Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010;95(6):2536–59.
  • LeBlanc ES, Nielson CM, Marshall LM, Lapidus JA, Barrett-Connor E, Ensrud KE, et al. The effects of serum testosterone, estradiol, and sex hormone binding globulin levels on fracture risk in older men. J Clin Endocrinol Metab 2009;94(9):3337–46.
  • Bauman WA, Spungen AM. Disorders of carbohydrate and lipid metabolism in veterans with paraplegia or quadriplegia: a model of premature aging. Metabolism 1994;43(6):749–56.
  • Garshick E, Kelley A, Cohen SA, Garrison A, Tun CG, Gagnon D, et al. A prospective assessment of mortality in chronic spinal cord injury. Spinal Cord 2005;43(7):408–16.
  • Spungen AM, Wang J, Pierson RN, Jr, Bauman WA. Soft tissue body composition differences in monozygotic twins discordant for spinal cord injury. J Appl Physiol 2000;88(4):1310–5.
  • Spungen AM, Adkins RH, Stewart CA, Wang J, Pierson RN, Jr, Waters RL, et al. Factors influencing body composition in persons with spinal cord injury: a cross-sectional study. J Appl Physiol 2003;95(6):2398–407.
  • Qin W, Bauman WA, Cardozo C. Bone and muscle loss after spinal cord injury: organ interactions. Ann N Y Acad Sci 2010;1211:66–84.
  • Wahman K, Nash MS, Lewis JE, Seiger A, Levi R. Increased cardiovascular disease risk in Swedish persons with paraplegia: The Stockholm spinal cord injury study. J Rehabil Med 2010;42(5):489–92.
  • Bors E, Engle ET, Rosenquist RC, Holliger VH. Fertility in paraplegic males: a preliminary report of endocrine studies. J Clin Endocrinol Metab 1950;10(4):381–98.
  • Clark MJ, Schopp LH, Mazurek MO, Zaniletti I, Lammy AB, Martin TA, et al. Testosterone levels among men with spinal cord injury: relationship between time since injury and laboratory values. Am J Phys Med Rehabil 2008;87(9):758–67.
  • Cortes-Gallegos V, Castaneda G, Alonso R, Arellano H, Cervantes C, Parra A. Diurnal variations of pituitary and testicular hormones in paraplegic men. Arch Androl 1982;8(3):221–6.
  • Nance PW, Shears AH, Givner ML, Nance DM. Gonadal regulation in men with flaccid paraplegia. Arch Phys Med Rehabil 1985;66(11):757–9.
  • Huang TS, Wang YH, Chiang HS, Lien YN. Pituitary-testicular and pituitary-thyroid axes in spinal cord-injured males. Metabolism 1993;42(4):516–21.
  • Huang TS, Wang YH, Lien IN. Suppression of the hypothalamus-pituitary somatotrope axis in men with spinal cord injuries. Metabolism 1995;44(9):1116–20.
  • Kikuchi TA, Skowsky WR, El-Toraei I, Swerdloff R. The pituitary-gonadal axis in spinal cord injury. Fertil Steril 1976;27(10):1142–5.
  • Safarinejad MR. Level of injury and hormone profiles in spinal cord-injured men. Urology 2001;58(5):671–6.
  • Tsitouras PD, Zhong YG, Spungen AM, Bauman WA. Serum testosterone and growth hormone/insulin-like growth factor-I in adults with spinal cord injury. Horm Metab Res 1995;27(6):287–92.
  • Wang YH, Huang TS, Lien IN. Hormone changes in men with spinal cord injuries. Am J Phys Med Rehabil 1992;71(6):328–32.
  • Durga A, Sepahpanah F, Regozzi M, Hastings J, Crane DA. Prevalence of testosterone deficiency after spinal cord injury. PMR 2011;3(10):929–32.
  • Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999;84(10):3666–72.
  • Bauman WA, Emmons RR, Cirnigliaro CM, Kirshblum SC, Spungen AM. Provocative stimulation of the pituitary-gonadotropin axis in hypogonadal and eugonadal persons with spinal cord injury. 91st Annual Meeting of the Endocrine Society; 2009; Washington, DC.
  • Ver Voort SM. Infertility in spinal-cord injured male. Urology 1987;29(2):157–65.
  • Linsenmeyer TA, Perkash I. Infertility in men with spinal cord injury. Arch Phys Med Rehabil 1991;72(10):747–54.
  • Anderson DC. Sex-hormone-binding globulin. Clin Endocrinol (Oxf) 1974;3(1):69–96.
  • Zumoff B, Strain GW, Miller LK, Rosner W, Senie R, Seres DS, et al. Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. J Clin Endocrinol Metab 1990;71(4):929–31.
  • Bertello P, Gurioli L, Faggiuolo R, Veglio F, Tamagnone C, Angeli A. Effect of ethanol infusion on the pituitary-testicular responsiveness to gonadotropin releasing hormone and thyrotropin releasing hormone in normal males and in chronic alcoholics presenting with hypogonadism. J Endocrinol Invest 1983;6(6):413–20.
  • Kirubakaran VR, Kumar VN, Powell BJ, Tyler AJ, Armatas PJ. Survey of alcohol and drug misuse in spinal cord injured veterans. J Stud Alcohol 1986;47(3):223–7.
  • Mauras N, Hayes V, Welch S, Rini A, Helgeson K, Dokler M, et al. Testosterone deficiency in young men: marked alterations in whole body protein kinetics, strength, and adiposity. J Clin Endocrinol Metab 1998;83(6):1886–92.
  • Sonmez A, Haymana C, Bolu E, Aydogdu A, Tapan S, Serdar M, et al. Metabolic syndrome and the effect of testosterone treatment in young men with congenital hypogonadotropic hypogonadism. Eur J Endocrinol 2011;64(5):59–64.
  • Bauman WA, Cirnigliaro CM, La Fountaine MF, Jensen AM, Wecht JM, Kirshblum SC, et al. A small-scale clinical trial to determine the safety and efficacy of testosterone replacement therapy in hypogonadal men with spinal cord injury. Horm Metab Res 2011;43(8):574–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.