431
Views
37
CrossRef citations to date
0
Altmetric
Original Articles

Phenotypic, antimicrobial susceptibility profile and virulence factors of Klebsiella pneumoniae isolated from buffalo and cow mastitic milk

, , &

References

  • Mullen KAE. Evaluation of herbal oils in various preparations for treating mastitis in dairy cattle [dissertation]. Raleigh, NC: North Carolina State University; 2013.
  • Locatelli C, Scaccabarozzi L, Pisoni G, Moroni P. CTX-M1 ESBL-producing Klebsiella pneumoniae subsp. pneumoniae isolated from cases of bovine mastitis. J Clin Microbiol. 2010;48:3822–3.
  • Lucheis SB. Epidemiological and molecular characteristics of Klebsiella pneumoniae infection in bovine dairy herds. São Paulo, SP: Agência Paulista de Tecnologia dos Agronegócios (APTA). Secretaria de Agricultura e Abastecimento; 2012.
  • Schukken Y, Chuff M, Moroni P, Gurjar A, Santisteban C, Welcome F, et al. The ‘other’ Gram-negative bacteria in mastitis: Klebsiella, serratia, and more. Vet Clin North Am: Food Anim Prac. 2012;28:239–56.
  • Izquierdo L, Coderch N, Piqué N, Bedini E, Corsaro MM, Merino S, et al. The Klebsiella pneumoniae wabG gene: role in biosynthesis of the core lipopolysaccharide and virulence. J Bacteriol. 2003;185:7213–21.
  • Fang CT, Chuang YP, Shun CT, Chang SC, Wang JT. A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J Exp Med. 2004;199:697–705.
  • Ma LC, Fang CT, Lee CZ, Shun CT, Wang JT. Genomic heterogeneity in Klebsiella pneumoniae strains is associated with primary pyogenic liver abscess and metastatic infection. J Infect Dis. 2005;192:117–28.
  • Lee HC, Chuang YC, Yu WL, Lee NY, Chang CM, Ko NY, et al. Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates: association with invasive syndrome in patients with community-acquired bacteraemia. J Intern Med. 2006;259:606–14.
  • Yu WL, Ko WC, Cheng KC, Lee HC, Ke DS, Lee CC, et al. Association between rmpA and magA genes and clinical syndromes caused by Klebsiella pneumoniae in Taiwan. Clin Infect Dis. 2006;42:1351–8.
  • Yeh KM, Kurup A, Siu LK, Koh YL, Fung CP, Lin JC, et al. Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan. J Clin Microbiol. 2007;45:466–71.
  • Johnson JG. Regulation of Type 3 fimbrial gene expression in Klebsiella pneumoniae [dissertation]. Iowa City, IA: The University of Iowa; 2011.
  • NMC. Laboratory handbook on bovine mastitis. Madison, WI: NMC; 1999.
  • Granier SA, Leflon-Guibout V, Goldstein FW, Nicolas-Chanoine MH. Enterobacterial repetitive intergenic consensus 1R PCR assay for detection of Raoultella sp. isolates among strains identified as Klebsiella oxytoca in the clinical laboratory. J Clin Microbiol. 2003;41:1740–2.
  • Alves MS, Dias RC, de Castro AC, Riley LW, Moreira BM. Identification of clinical isolates of indole-positive and indole-negative Klebsiella spp. J Clin Microbiol. 2006;44:3640–6.
  • Zadoks RN, Middleton JR, McDougall S, Katholm J, Schukken YH. Molecular epidemiology of mastitis pathogens of dairy cattle and comparative relevance to humans. J Mammary Gland Biol Neoplasia. 2011;16:357–72.
  • Forsbäck L, Lindmark-Månsson H, Andrén A, Svennersten-Sjaunja K. Evaluation of quality changes in udder quarter milk from cows with low-to-moderate somatic cell counts. Animal. 2010;4:617–26.
  • Yu VL, Hansen DS, Ko WC, Sagnimeni A, Klugman KP, von Gottberg A, et al. Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections. Emerg Infect Dis. 2007;13:986–93.
  • CLSI. Performance standards for antimicrobial susceptibility testing; twentieth informational supplement. M100-S20, Vol. 30, No. 1. Wayne, PA: CLSI; 2010.
  • FAO/WHO/OIE. Joint FAO/WHO/OIE Expert Meeting on Critically Important Antimicrobials. Report of a meeting held in FAO; 26–30 November 2007; Rome, Italy. FAO: Rome, Italy and WHO: Geneva, Switzerland, 2008.
  • WHO. Critically important antimicrobials for human medicine. 2nd Revision. Geneva: WHO Advisory Group on Integrated Surveillance of Antimicrobial Resistance (AGISAR), Department of Food Safety and Zoonoses; 2009.
  • Qadir F, Hossain SA, Cizna’r I, Haider K, Ljungh A, Wadstrom T, et al. Congo red binding and salt aggregation as indicators of virulence in Shigella species. J Clin Microbiol. 1988;26:1343–8.
  • Raja RK, Ramesh N, Maripandi A. Invasion and interaction studies of Salmonella Typhimurium sub sp Enteritidis in Vero and MDCK cell lines. Adv Biol Res. 2010;4:86–91.
  • NRC. Guide for the care and use of laboratory animals. Committee for the Update of the Guide for the Care and Use of Laboratory Animals Institute for Laboratory Animal Research Division on Earth and Life Studies. Washington, DC: National Research Council, National Academies Press; 2011.
  • Munoz MA, Welcome FL, Schukken YH, Zadoks RN. Molecular epidemiology of two Klebsiella pneumonia mastitis outbreaks on a dairy farm in New York State. J Clin Microbiol. 2007;45:3964–71.
  • Giannella RA. Suckling mouse model for detection of heat stable Escherichia coli enterotoxin: characteristics of the model. Infect Immun. 1976;14:95–9.
  • Liu Y, Liu C, Zheng W, Zhang X, Yu J, Gao Q, et al. PCR detection of Klebsiella pneumoniae in infant formula based on 16S–23S internal transcribed spacer. Int J Food Microbiol. 2008;125:230–5.
  • Turton JF, Baklan H, Siu LK, Kaufmann ME, Pitt TL. Evaluation of a multiplex PCR for detection of serotypes K1, K2 and K5 in Klebsiella sp. and comparison of isolates within these serotypes. FEMS Microbiol Lett. 2008;284:247–52.
  • Podschun R, Ullmann U. Klebsiella spp. as Nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev. 1998;11:589–603.
  • Nadasy KA, Domiati-Saad R, Tribble MA. Invasive Klebsiella pneumoniae syndrome in North America. Clin Infect Dis. 2007;45:e25–8.
  • Kitchel B, Rasheed JK, Patel JB, Srinivasan A, Navon-Venezia S, Carmeli Y, et al. Molecular epidemiology of KPC-producing Klebsiella pneumoniae isolates in the United States: clonal expansion of multilocus sequence type 258. Antimicrob Agents Chemother. 2009;53:3365–70.
  • Tiwari JG, Babra C, Tiwari HK, Williams V, de Wet S, Gibson J, et al. Trends in therapeutic and prevention strategies for management of bovine mastitis: an overview. J Vacc Vaccinol. 2013;4:176.
  • Hoe FG, Ruegg PL. Relationship between antimicrobial susceptibility of clinical mastitis pathogens and treatment outcome in cows. J Am Vet Med Assoc. 2005;227:1461–8.
  • Paulin-Curlee GG, Singer RS, Sreevatsan S, Isaacson R, Reneau J, Foster D, et al. Genetic diversity of mastitis-associated Klebsiella pneumoniae in dairy cows. J Dairy Sci. 2007;90:3681–9.
  • Vecht U, Meijers KC, Wisselink HJ. Klebsiella pneumonia mastitis as a dairying problem. Tijdschr Diergeneeskd. 1987;112:653–9.
  • Sampimon OC, Sol J, Kock PA. Een uitbraak van Klebsiella pneumonia mastitis. Tijdschr Diergeneeskd. 2006;131:2–4.
  • Botrel MA, Haenni M, Morignat E, Sulpice P, Madec JY, Calavas D. Distribution and antimicrobial resistance of clinical and subclinical mastitis pathogens in dairy cows in Rhône-Alpes, France. Foodborne Pathog Dis. 2010;7:479–87.
  • Thompson-Crispi KA, Filippo M, Mallard BA. Incidence rates of clinical mastitis among canadian holsteins classified as high, average, or low immune responders. Clin Vacc Immunol. 2013;20:106–12.
  • Pitkala A, Haveri M, Pyorala S, Myllys V, Honkanen-Buzalski T. Bovine mastitis in Finland 2001 — prevalence, distribution of bacteria, and antimicrobial resistance. J Dairy Sci. 2004;87:2433–41.
  • Gianneechini R, Concha C, Rivero R, Delucci I, Moreno López J. Occurrence of clinical and sub-clinical mastitis in dairy herds in the West Littoral region in Uruguay. Acta Vet Scand. 2002;43:221–30.
  • Schwarz D, Diesterbeck US, Failing K, König S, Brügemann K, Zschöck M, et al. Somatic cell counts and bacteriological status in quarter foremilk samples of cows in Hesse, Germany — a longitudinal study. J Dairy Sci. 2010;93:5716–28.
  • Östensson K, Lam V, Sjögren N, Wredle E. Prevalence of subclinical mastitis and isolated udder pathogens in dairy cows in Southern Vietnam. Trop Anim Health Prod. 2013;45:979–86.
  • Swartz R, Jooste PJ, Novello JC. Prevalence and type of bacteria associated with sub-clinical mastitis in Bloemfontein dairy herds. J South Afr Vet Assoc. 1984;55:61–4.
  • Perry BD, Carter ME, Hill FW, Milne JAC. Mastitis and milk production in cattle in a communal land of Zimbabwe. Brit Vet J. 1987;143:44–50.
  • Makaya PV, Aarestrup FM, Olsen JE. Distribution and antibiotic resistance patterns of common mastitis pathogens (Gram-positive cocci) in selected dairy herds of three farming dairy sectors in Zimbabwe. Zimbabwe Vet J. 1996;27:65–75.
  • Getahun K, Kelay B, Bekana M, Lobago F. Bovine mastitis and antibiotic resistance patterns in Selalle small holder dairy farms, central Ethiopia. Trop Anim Health Prod. 2008;40:261–8.
  • Lakew M, Tolosa T, Tigre W. Prevalence and major bacterial causes of bovine mastitis in Asella, south eastern Ethiopia. Trop Anim Health Prod. 2009;41:1525–30.
  • Mdegela RH, Ryoba R, Karimuribo ED, Phiri EJ, Löken T, Reksen O, et al. Prevalence of clinical and subclinical mastitis and quality of milk on smallholder dairy farms in Tanzania, J South Afr Vet Assoc. 2009;80:163–8.
  • Petzer IM, Karzis J, Watermeyer JC, van der Schans TJ, van Reenen R. Trends in udder health and emerging mastitogenic pathogens in South African dairy herds, J South Afr Vet Assoc. 2009;80:17–22.
  • Katsande S, Matope G, Ndengu M, Pfukenyi DM. Prevalence of mastitis in dairy cows from smallholder farms in Zimbabwe. Onderstepoort J Vet Res. 2013;80:523.
  • Carroll EJ. Bactericidal activity of bovine serums against coliform organisms isolated from milk of mastitic udders, udder skin, and environment. Am J Vet Res. 1971;32:689–701.
  • Nonnecke BJ, Newbould FH. Biochemical and serologic characterization of Klebsiella strains from bovine mastitis and the environment of the dairy cow. Am J Vet Res. 1984;45:2451–4.
  • Munoz MA, Zadoks RN. Patterns of fecal shedding of Klebsiella by dairy cows. J Dairy Sci. 2007;90:1220–4.
  • Kikuchi N, Kagota C, Nomura T, Hiramune T, Takahashi T, Yanagawa R. Plasmid profiles of Klebsiella pneumonia isolated from bovine mastitis. Vet Microbiol. 1995;47:9–15.
  • Munoz MA, Ahlström C, Rauch BJ, Zadoks RN. Fecal shedding of Klebsiella pneumonia by dairy cows. J Dairy Sci. 2006;89:3425–30.
  • Verbist B, Piessens V, Van Nuffel A, De Vuyst L, Heyndrickx M, Herman L, et al. Sources other than unused sawdust can introduce Klebsiella pneumoniae into dairy herds. J Dairy Sci. 2011;94:2832–9.
  • Jasper DE, Dellinger JD. Teat apex coliform populations and coliform mastitis — a herd study. Cornell Vet. 1975;65:380–92.
  • Talbot HW JR., Yamamoto DK, Smith MW, Seidler RJ. Antibiotic resistance and its transfer among clinical and nonclinical klebsiella strains in botanical environments. Appl Environ Microbiol. 1980;39:97–104.
  • Zdanowicz M, Shelford JA, Tucker CB, Weary DM, von Keyserlingk MA. Bacterial populations on teat ends of dairy cows housed in free stalls and bedded with either sand or sawdust. J Dairy Sci. 2004;87:1694–701.
  • Struve C, Krogfelt KA. Pathogenic potential of environmental Klebsiella pneumonia isolates. Environ Microbiol. 2004;6:584–90.
  • Paulin-Curlee GG, Sreevatsan S, Singer RS, Isaacson R, Reneau J, Bey R, et al. Molecular subtyping of mastitis-associated Klebsiella pneumoniae isolates shows high levels of diversity within and between dairy herds. J Dairy Sci. 2008;91:554–63.
  • Braman SK, Eberhart RJ, Asbury MA, Hermann GJ. Capsular types of Klebsiella pneumonia associated with bovine mastitis. J Am Vet Med Assoc. 1973;162:109–11.
  • Nomura T, Moriya H, Kikuchi N, Hiramune T. Capsular types of Klebsiella associated with bovine mastitis in Japan. Nippon Juigaku Zasshi. 1989;51:1287–9.
  • White DG, McDermott PF. Emergence and transfer of antibiotic resistance. J Dairy Sci. 2001;84:E151–5.
  • Erskine RJ, Bartlett PC, VanLente JL, Phipps CR. Efficacy of systemic ceftiofur as a therapy for severe clinical mastitis in dairy cattle. J Dairy Sci. 2002;85:2571–5.
  • WHO. Tackling antibiotic resistance from a food safety perspective in Europe. Copenhagen: WHO Regional Office for Europe; 2011.
  • FDA. #209 Communications, 13 April 2012.
  • Ofek I, Kabha K, Athamna A, Frankel G, Wozniak DJ, Hasty DL, et al. Genetic exchange of determinants for capsular polysaccharide biosynthesis between Klebsiella pneumoniae strains expressing serotypes K2 and K21a. Infect Immun. 1993;61:4208–16.
  • Davis TJ, Matsen JM. Prevalence and characteristics of Klebsiella species: relation to association with a hospital environment. J Infect Dis. 1974;130:402–5.
  • Rosenthal S, Tager IB. Prevalence of Gram-negative rods in the normal pharyngeal flora. Ann Intern Med. 1975;83:355–7.
  • Fang CT, Lai SY, Yi WC, Hsueh PR, Liu KL, Chang SC. Klebsiella pneumoniae genotype K1: an emerging pathogen that causes septic ocular or central nervous system complications from pyogenic liver abscess. Clin Infect Dis. 2007;45:284–93.
  • Nassif X, Honore N, Vasselon T, Cole ST, Sansonetti PJ. Positive control of colanic acid synthesis in Escherichia coli by rmpA and rmpB two virulence-plasmid genes of Klebsiella pneumoniae. Mol Microbiol. 1989;3:1349–59.
  • Cheng HY, Chen YS, Wu CY, Chang HY, Lai YC, Peng HL. RmpA regulation of capsular polysaccharide biosynthesis in Klebsiella pneumoniae CG43. J Bacteriol. 2010;192:3144–58.
  • Shon AS, Bajwa RP, Russ TA. Hypervirulent (hypermucoviscous) Klebsiella pneumoniae: a new and dangerous breed. Virulence. 2013;4:107–18.
  • Soto E, LaMon V, Griffin M, Keirstead N, Palmour R. Phenotypic and genotypic characterization of Klebsiella pneumoniae isolates recovered from nonhuman primates. J Wildlife Dis. 2012;48:603–11.
  • Yu WL, Ko WC, Cheng KC, Lee CC, Lai CC, Chuang YC. Comparison of prevalence of virulence factors for Klebsiella pneumoniae liver abscesses between isolates with capsular K1/K2 and non-K1/K2 serotypes. Diag Microbiol Infect Dis. 2008;62:1–6.
  • Munoz MA, Bennett GJ, Ahlström C, Griffiths HM, Schukken YH, Zadoks RN. Cleanliness scores as indicator of Klebsiella exposure in dairy cows. J Dairy Sci. 2008;91:3908–16.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.