The role of genetic factors in the etiology of temporomandibular disorders: a review

References

• de Leeuw R, Klasser G D, editors. Orofacial pain: guidelines for assessment, diagnosis, and management. 5th ed. Chicago, IL: Quintessence; 2013. p. 127–86.
   Google Scholar
• Landi N, Manfredini D, Tognini F, Romagnoli M, Bosco M. Quantification of the relative risk of multiple occlusal variables for muscle disorders of the stomatognathic system. J Prosthet Dent. 2004;92:190–5.
   PubMed Web of Science ®Google Scholar
• Michelotti A, Farella M, Gallo LM, Veltri A, Palla S, Martina R. Effect of occlusal interference on habitual activity of human masseter. J Dent Res. 2005;84:644–8.
   PubMed Web of Science ®Google Scholar
• Selaimen CM, Jeronymo JC, Brilhante DP, Lima EM, Grossi PK, Grossi ML. Occlusal risk factors for temporomandibular disorders. Angle Orthod. 2007;77:471–7.
   PubMed Web of Science ®Google Scholar
• de Leeuw R, Klasser G D, editors. Orofacial pain: guidelines for assessment, diagnosis, and management. 5th ed. Chicago, IL: Quintessence; 2013. p. 1–23.
   Google Scholar
• Suvinen TI, Reade PC, Kemppainen P, Könönen M, Dworkin SF. Review of aetiological concepts of temporomandibular pain disorders: towards a biopsychosocial model for integration of physical disorder factors with psychological and psychosocial illness impact factors. Eur J Pain. 2005;9:613–33.
   PubMed Web of Science ®Google Scholar
• Klasser GD, Greene CS. The changing field of temporomandibular disorders: what dentists need to know. J Can Dent Assoc. 2009;75:49–53.
   PubMedGoogle Scholar
• Reid KI, Greene CS. Diagnosis and treatment of temporomandibular disorders: an ethical analysis of current practices. J Oral Rehabil. 2013;40:546–61.
   PubMed Web of Science ®Google Scholar
• Melis M. Dr. Melis comments on the editorials published in CRANIO in 2011. Cranio 2011;29:253.
   PubMed Web of Science ®Google Scholar
• de Leeuw R, editor. Orofacial pain: guidelines for assessment, diagnosis, and management, 4th ed. Chicago, IL: Quintessence; 2008. p. 129–204.
   Google Scholar
• Diatchenko L, Slade GD, Nackley AG, Bhalang K, Sigurdsson A, Belfer I, et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet. 2005;14:135–43.
   PubMed Web of Science ®Google Scholar
• Heiberg A, Helöe LA, Magnus P, Berg K, Nance WE. Myofascial pain dysfunction (MPD) syndrome in twins. Community Dent Oral Epidemiol. 1980;8:434–6.
   PubMed Web of Science ®Google Scholar
• Michalowicz BS, Pihlstrom BL, Hodges JS, Bouchard TJJr. No heritability of temporomandibular joint signs and symptoms. J Dent Res. 2000;79:1573–8.
   PubMed Web of Science ®Google Scholar
• Matsuka Y, Nagamatsu C, Itoh S, Tomonari T, Makki A, Minakuchi H, et al. Comparison of inter-twin concordance in symptoms of temporomandibular disorders: a preliminary investigation in an adolescent twin population. Cranio 2007;25:23–9.
   PubMed Web of Science ®Google Scholar
• Raphael KG, Marbach JJ, Gallagher RM, Dohrenwend BP. Myofascial TMD does not run in families. Pain. 1999;80:15–22.
   PubMed Web of Science ®Google Scholar
• Liljeström MR, Aromaa M, Bell YL, Jämsä T, Helenius H, Virtanen R, et al. Familial occurrence of signs of temporomandibular disorders in headache children and their mothers. Acta Odontol Scand. 2007;65:134–40.
   PubMed Web of Science ®Google Scholar
• Herken H, Erdal E, Mutlu N, Barlas O, Cataloluk O, Oz F, et al. Possible association of temporomandibular joint pain and dysfunction with a polymorphism in the serotonin transporter gene. Am J Orthod Dentofac Orthop. 2001;120:308–13.
   PubMed Web of Science ®Google Scholar
• Ojima K, Narita N, Narita M. Temporomandibular disorder is associated with serotonin transporter gene polymorphism in the Japanese population. Biopsichosoc Med. 2007;1:3.
   PubMedGoogle Scholar
• Mutlu N, Erdal ME, Herken H, Oz G, Bayazit YA. T102C polymorphism of the 5-HT2A receptor gene may be associated with temporomandibular dysfunction. Oral Dis. 2004;10:349–52.
   PubMed Web of Science ®Google Scholar
• de Freitas LV, Lopes AC, Piatto VB, Maniglia JV. Association of temporomandibular dysfunction with the 102T-C polymorphism in the serotonin receptor gene in Brazilian patients. Arch Med Sci. 2013;9:1013–8.
   PubMed Web of Science ®Google Scholar
• Smith SB, Maixner DW, Greenspan JD, Dubner R, Fillingim RB, Ohrbach R, et al. Potential genetic risk factors for chronic TMD: genetic associations from the OPPERA case control study. J Pain. 2011;12:(11 Suppl):T92–101.
   PubMed Web of Science ®Google Scholar
• Slade GD, Smith SB, Zaykin DV, Tchivileva IE, Gibson DG, Yuryev A, et al. Facial pain with localized and widespread manifestations: separate pathways of vulnerability. Pain. 2013;154:2335–43.
   PubMed Web of Science ®Google Scholar
• Etoz OA, Ataoglu H, Erdal ME. Association between tryptophan hydroxylase gene polymorphism and painful non-osseous temporomandibular disorders. Saudi Med. 2008;29:1352–4.
   PubMed Web of Science ®Google Scholar
• Michelotti A, Liguori R, Toriello M, D’Antò V, Vitale D, Castaldo G, et al. Catechol-O- methyltransferase (COMT) gene polymorphisms as risk factor in temporomandibular disorders patients from southern Italy. Clin J Pain. 2014;30:129–33.
   PubMed Web of Science ®Google Scholar
• Diatchenko L, Anderson AD, Slade GD, Fillingim RB, Shabalina SA, Higgins TJ, et al. Three major haplotypes of the beta2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder. Am J Med Genet B Neuropsychiatr Genet. 2006;141B:449–62.
   PubMed Web of Science ®Google Scholar
• Aneiros-Guerrero A, Lendinez AM, Palomares AR, Perez-Nevot B, Aguado L, Mayor-Olea A, et al. Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder. BMC Med Genet. 2011;12:75–83.
   PubMed Web of Science ®Google Scholar
• Ribeiro-Dasilva MC, Peres Line SR, Leme Godoy dos Santos MC, Arthuri MT, Hou W, Fillingim RB, et al. Estrogen receptor-alpha polymorphisms and predisposition to TMJ disorder. J Pain. 2009;10:527–33.
   PubMed Web of Science ®Google Scholar
• Kang SC, Lee DG, Choi JH, Kim ST, Ahn HJ. Association between estrogen receptor polymorphism and pain susceptibility in female temporomandibular joint osteoarthritis patients. Int J Oral Maxillofac Surg. 2007;36:391–4.
   PubMed Web of Science ®Google Scholar
• Huang B, Takahashi K, Sakata T, Kiso H, Sugal M, Fujimura K, et al. Increased risk of temporomandibular joint closed-lock: a case–control study of ANKH polymorphisms. PLoS One. 2011;6:e25503.
   PubMed Web of Science ®Google Scholar
• Henry CH, Nikaein A, Wolford LM. Analysis of human leukocyte antigens in patients with internal derangement of the temporomandibular joint. J Oral Maxillofac Surg. 2002;60:778–83.
   PubMed Web of Science ®Google Scholar
• Learreta JA, Bono AE, Durst AC. HLA analysis in patients with degenerative diseases of the temporomandibular joint. Cranio 2011;29:32–7.
   PubMed Web of Science ®Google Scholar
• Planello AC, Campos MI, Meloto CB, Secolin R, Rizatti-Barbosa CM, Line SR, et al. Association of matrix metalloproteinase gene polymorphism with temporomandibular joint degeneration. Eur J Oral Sci. 2011;119:1–6.
   PubMed Web of Science ®Google Scholar
• Slade GD, Conrad MS, Diatchenko L, Rashid NU, Zhong S, Smith S, et al. Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness. Pain. 2011;152:2802–12.
   PubMed Web of Science ®Google Scholar
• Etoz OA, Erdal ME, Herken H, Bayazit YA. Lack of association between the 308GA polymorphism of the tumor necrosis factor alpha gene and temporomandibular dysfunction. Pain Clin. 2006;18:175–80.
   Google Scholar
• Kim BS, Kim YK, Yun PY, Lee E, Bae J. The effects of estrogen receptor α polymorphism on the prevalence of symptomatic temporomandibular disorders. J Oral Maxillofac Surg. 2010;68:2975–9.
   PubMed Web of Science ®Google Scholar
• Smith SB, Mir E, Bair E, Slade GD, Dubner R, Fillingim RB, et al. Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study. J Pain. 2013;14(Suppl):T91–101.
   PubMed Web of Science ®Google Scholar
• Meloto CB, Serrano PO, Ribeiro-DaSilva MC, Rizzati-Barbosa CM. Genomics and the new perspectives for temporomandibular disorders. Arch Oral Biol. 2011;56:1181–91.
   PubMed Web of Science ®Google Scholar
• Kopp S. The influence of neuropeptides, serotonin, and interleukin 1beta on temporomandibular joint pain and inflammation. J Oral Maxillofac Surg. 1998;56:189–91.
   PubMed Web of Science ®Google Scholar
• Kopp S. Neuroendocrine, immune, and local responses related to temporomandibular disorders. J Orofac Pain. 2001;15:9–28.
   PubMedGoogle Scholar
• Costigan M, Moss A, Latremoliere A, Johnston C, Verma-Gandhu M, Herbert TA, et al. T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity. J Neurosci. 2009;29:14415–22.
   PubMed Web of Science ®Google Scholar
• Kleinschnitz C, Hofstetter HH, Meuth SG, Braeuninger S, Sommer C, Stoll G. T-cell infiltration after chronic constriction injury of mouse sciatic nerve is associated with interleukin-17 expression. Exp Neurol. 2006;200:480–5.
   PubMed Web of Science ®Google Scholar
• Nackley-Neely AG, Tan KS, Fecho K, Flood P, Diatchenko L, Maixner W. Catechol-O- methyltransferase inhibition increases pain sensitivity through activation of both β2 and β3 adrenergic receptors. Pain. 2007;128:199–208.
   PubMed Web of Science ®Google Scholar
• Tchivileva IE, Lim PF, Smith SB, Slade GD, Diatchenko L, McLean SA, et al. Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study. Pharmacogenet Genomics. 2010;20:239–48.
   PubMed Web of Science ®Google Scholar
• Carra MC, Huynh N, Lavigne G. Sleep bruxism: a comprehensive overview for the dental clinician interested in sleep medicine. Dent Clin North Am. 2012;56:387–413.
   PubMedGoogle Scholar
• Manfredini D, Lobbezoo F. Relationship between bruxism and temporomandibular disorders: a systematic review of literature from 1998 to 2008. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:e26–50.
   PubMed Web of Science ®Google Scholar
• Wang J, Chao Y, Wan Q, Zhu Z. The possible role of estrogen in the incidence of temporomandibular disorders. Med Hypotheses. 2008;71:564–7.
   PubMed Web of Science ®Google Scholar
• Yamaza T, Masuda KF, Atsuta I, Nishijima K, Kido MA, Tanaka T. Oxidative stress- induced DNA damage in the synovial cells of the temporomandibular joint in the rat. J Dent Res. 2004,83:619–24.
   PubMed Web of Science ®Google Scholar
• Ueno T, Yamada M, Sugita Y, Ogawa T. N-acetyl cysteine protects TMJ chondrocytes from oxidative stress. J Dent Res. 2011;90:353–9.
   PubMed Web of Science ®Google Scholar
• Ogura N, Tobe M, Sakamaki H, Nagura H, Abiko Y, Kondoh T. Tumor necrosis factor-α increases chemokine gene expression and production in synovial fibroblasts from human temporomandibular joint. J Oral Pathol Med. 2005;34:357–63.
   PubMed Web of Science ®Google Scholar
• Tobe M, Ogura N, Abiko Y, Nagura H. Interleukin-1β production and bene expression in synovial cells from human temporomandibular joint. J Oral Mxillofac Surg. 2002;60:741–7.
   PubMed Web of Science ®Google Scholar
• Chen H, Slade G, Lim PF, Miller V, Maixner W, Diatchenko L. Relationship between temporomandibular disorders, widespread palpation tenderness and multiple pain conditions: a case–control study. J Pain. 2012;13:1016–27.
   PubMed Web of Science ®Google Scholar