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Journal of Chemotherapy Volume 13, 2001 - Issue 1
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Articles

Antitrypanosomal Properties of Cis-Platinum-Pentamidine Bromide, Thiocyanate and Seleniocyanate on Trypanosoma brucei brucei Mouse and Sheep Models

P.M. Loiseau
,
G. Dreyfuss
,
L. Doadrio
,
E. Parrondo
&
D.G. Craciunescu
Pages 59-65 | Published online: 18 Jul 2013

REFERENCES

  • Kuzoe FAS. Current situation of African trypanosomia-sis. Acta Trop 1993; 54: 153–162.
  • Kinnamon KE, Steck EA, Rane DS. Activity of antitu-mor drugs against African trypanosomes. Antimicrob Agents Chemother 1989; 33: 881–885.
  • Farrell NP, Williamson J, McLaren DJM. Trypanocidal and antitumor activity of platinum metal and platinum metal drug dual function complexes. Biochem Pharmacol 1984; 33: 961–971.
  • Dreyfuss G, Gayral P, Dubost G, Nicolas JA, Craciunescu DG. Activité antiparasitaire du Cis-Pt(11)-pentami-dine dans la trypanosomose expérimentale du mouton A Trypanosoma brucei brucei. Bull Soc Path Ex 1988; 81: 626–631.
  • Dreyfuss G, Pénicaut B, Nicolas JA, Craciunescu D, Loiseau PM. Trypanocidal activity and platinum plasma kinet-ics of cis-pt-pentamidine iodide in Trypanosoma brucei sheep model. Trop Med Parasitol 1993; 44: 95–98.
  • Loiseau PM, Craciunescu DG, Doadrio-Villarejo JC, Certad-Fombona G, Gayral P. Pharmacomodulations on new organometallic complexes of Ir, Pt, Rh, Pd, Os: in vitro and in vivo trypanocidal study against Trypanosoma brucei. Trop Med Parasitol 1992; 43: 110–114.
  • Dreyfuss G, Loiseau PM, LachAtre G, Pénicaut B, Nicolas JA, Craciunescu D. Trypanosoma brucei brucei: antitrypanosomal evaluation of stilbamidinium hexachloroiridi-ate on the murine CNS model and iridium serum kinetics in infected sheep. Trop Med Parasitol 1995; 46: 41–44.
  • Loiseau PM, Dreyfuss G, Daulouède S, LachAtre G, Vincendeau P, Craciunescu DG. Trypanocidal effect of Ir-(COD)-pentamidine tetraphenylborate on Trypanosoma bru-cei and T.b.gambiense rodent models and serum kinetics in sheep. Trop Med Int Health 1997; 2: 19–27.
  • Gayral P, Loiseau PM, Craciunescu DG. Complexes organométalligues d'iridium ayant une action antiparasitaire. French Patent n° 9200669, 22/01/1992.
  • Loiseau PM, Wolf JG, Gayral P. Spiroarsoranes of sec-ond generation: evaluation of trypanocidal properties against Trypanosoma brucei brucei. Trop Med Parasitol 1993; 44: 32–36.
  • Lanham S, Godfrey DG. Isolation of salivarian try-panosomes from man and other mammals using DEAE-cellu-lose. Exp Parasitol 1970; 28: 521–531.

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