References
- PerskyABrazeauGClinical pharmacology of the dietary supplement creatine monohydratePharmacol Rev200153 161 176 1:CAS:528:DC%2BD3MXkt1Gnurs%3D 11356982
- BurkeDGCandowDGChilibeckPDMacNeilLGRoyBDTarnopolskyMAZiegenfussTEffect of creatine supplementation and resistance-exercise training on muscle insulin-like growth factor in young adultsInt J Sport Nutr Exerc Metab200818 389 398 1:CAS:528:DC%2BD1cXhtVOnu7bP 18708688
- GualanoBArtioliGGPoortmansJRLancha JuniorAHExploring the therapeutic role of creatine supplementationAmino Acids201038 31 44 1:CAS:528:DC%2BC3cXhtVehtLs%3D https://doi.org/10.1007/s00726-009-0263-6 19253023
- TarnopolskyMACreatine as a therapeutic strategy for myopathiesAmino Acids201140 1397 1407 1:CAS:528:DC%2BC3MXkvFWqt70%3D https://doi.org/10.1007/s00726-011-0876-4 21399918
- BufordTKreiderRStoutJGreenwoodMCampbellBSpanoMZiegenfussTLopezHLandisJAntonioJInternational Society of Sports Nutrition position stand: creatine supplementation and exerciseJ Int Soc Sports Nutr20074 6 2048496 https://doi.org/10.1186/1550-2783-4-6 17908288
- American College of Sport Medicine Round Table, the physiological and health effects of oral creatine supplementationMed Sci Sports Exc200032 706 717 https://doi.org/10.1097/00005768-200003000-00024
- BranchJDEffects of creatine supplementation on body composition and performace: a meta análisisInt J Sports Nutr Exerc Metabol200313 I198-122
- RawsonESVolekJSEffects of creatine supplementation and resistance training on muscle strength and weightlifting performanceJ Strength Cond Res200317 822 831 14636102
- VolekJSKraemerWJCreatine suplemetation: its effects on human muscular performance and body compositionJ Strength Cond Res199610 200 210
- BembenMLamontHCreatine supplementation and exercise performance: recent findingsSports Med200535 107 125 https://doi.org/10.2165/00007256-200535020-00002 15707376
- BrosnanJTda SilvaRPBrosnanMEThe metabolic burden of creatine synthesisAmino Acids201140 1325 1331 1:CAS:528:DC%2BC3MXkvFWqtrg%3D https://doi.org/10.1007/s00726-011-0853-y 21387089
- SnowRJMurphyRMCreatine and the creatine transporter: a reviewMol Cell Biochem2001224 169 181 1:CAS:528:DC%2BD3MXot1Ciu78%3D https://doi.org/10.1023/A:1011908606819 11693194
- SnowRJMurphyRMFactors influencing creatine loading into human skeletal muscleExerc Sport Sci Rev200331 154 158 https://doi.org/10.1097/00003677-200307000-00010 12882483
- SchochRDWilloughbyDGreenwoodMThe regulation and expression of the creatine transporter: a brief review of creatine supplementation in humans and animalsJ Int Soc Sports Nutr20063 60 66 2129152 https://doi.org/10.1186/1550-2783-3-1-60 18500965
- HicknerRDyckDSklarJHatleyHByrdPEffect of 28 days of creatine ingestion on muscle metabolism and performance of a simulated cycling road raceJ Int Soc Sports Nutr20107 26 2909923 https://doi.org/10.1186/1550-2783-7-26 20609257
- HespelPDeraveWErgogenic effects of creatine in sports and rehabilitationSubcell Biochem200746 245 259 https://doi.org/10.1021/bi061646s 18652080
- CaseyAGreenhaffPDoes dietary creatine supplementation play a role in skeletal muscle metabolism and performance?Am J Clin Nutr200072 607S 617S 1:CAS:528:DC%2BD3cXlsFyhsb8%3D 10919967
- VolekJDuncanNMazzettiSStaronRPutukianMGómezAPearsonDFinkWKraemerWPerformance and muscle fiber adaptations to creatine supplementation and heavy resistance trainingMed Sci Sports Exerc199931 1147 1156 1:CAS:528:DyaK1MXlsVCqsr8%3D https://doi.org/10.1097/00005768-199908000-00011 10449017
- DempseyRMazzoneMMeurerLDoes oral creatine supplementation improve strength? A meta-analysisJ Fam Pract200251 945 951 12485548
- KreiderRBEffects of creatine supplementation on performance and training adaptationsMol Cell Biochem2003244 89 94 1:CAS:528:DC%2BD3sXht12jsb4%3D https://doi.org/10.1023/A:1022465203458 12701815
- van LoonLOosterlaarAHartgensFHesselinkMSnowRWagenmakersAEffects of creatine loading and prolonged creatine supplementation on body composition, fuel selection, sprint and endurance performance in humansClin Sci (Lond)2003104 153 162 1:CAS:528:DC%2BD3sXmslGgsA%3D%3D https://doi.org/10.1042/CS20020159
- VolekJRawsonEScientific basis and practical aspects of creatine supplementation for athletesNutrition200420 609 614 1:CAS:528:DC%2BD2cXltVGitL4%3D https://doi.org/10.1016/j.nut.2004.04.014 15212742
- JakobiJRiceCCurtinSMarshGContractile properties, fatigue and recovery are not influenced by short-term creatine supplementation in human muscleExp Physiol200085 451 460 1:CAS:528:DC%2BD3cXmsV2mtbc%3D https://doi.org/10.1111/j.1469-445X.2000.02021.x 10918084
- BembenMGWittenMSCarterJMEliotKAKnehansAWBembenDAThe effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older menJ Nutr Health Aging201014 155 159 1:CAS:528:DC%2BC3cXlt1Sit74%3D https://doi.org/10.1007/s12603-009-0124-8 20126965
- SafdarAYardleyNSnowRMelovSTarnopolskyMGlobal and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementationPhysiol Genomics200832 219 228 1:CAS:528:DC%2BD1cXmt1Wjtbc%3D https://doi.org/10.1152/physiolgenomics.00157.2007 17957000
- SaremiAGharakhanlooRSharghiSGharaatiMLarijaniBOmidfarKEffects of oral creatine and resistance training on serum myostatin and GASP-1Mol Cell Endocrinol2010317 25 30 1:CAS:528:DC%2BC3cXhtlyls7c%3D https://doi.org/10.1016/j.mce.2009.12.019 20026378
- BazzucchiIFeliciFSacchettiMEffect of short-term creatine supplementation on neuromuscular functionMed Sci Sports Exerc200941 1934 41 1:CAS:528:DC%2BD1MXhtFGjtrjO https://doi.org/10.1249/MSS.0b013e3181a2c05c 19727018
- BranchJEffect of creatine supplementation on body composition and performance: a meta-analysisInt J Sport Nutr Exerc Metab200313 198 226 1:CAS:528:DC%2BD3sXlsVemtrc%3D 12945830
- CribbPJWilliamsADHayesAA creatine-protein-carbohydrate supplement enhances responses to resistance trainingMed Sci Sports Exerc200739 1960 1968 1:CAS:528:DC%2BD2sXht1KrurvK https://doi.org/10.1249/mss.0b013e31814fb52a 17986903
- PariseGMihicSMacLennanDYarasheskiKETarnopolskyMAEffects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesisJ Appl Physiol200191 1041 1047 1:CAS:528:DC%2BD3MXmvV2qsb4%3D 11509496
- LouisMPoortmansJRFrancauxMHultmanEBerreJBoisseauNYoungVRSmithKMeier-AugensteinWBabrajJA et al Creatine supplementation has no effect on human muscle protein turnover at rest in the postabsorptive or fed statesAm J Physiol Endocrinol Metab2003284 E764 E770 1:CAS:528:DC%2BD3sXjtlykurk%3D https://doi.org/10.1152/ajpendo.00338.2002 12475751
- DeldicqueLAthertonPPatelRTheisenDNielensHRennieMFrancauxMEffects of resistance exercise with and without creatine supplementation on gene expression and cell signaling in human skeletal muscleJ Appl Physiol2008104 371 378 1:CAS:528:DC%2BD1cXjtlelt7Y%3D https://doi.org/10.1152/japplphysiol.00873.2007 18048590
- HarpJBGoldsteinSPhillipsLSNutrition and somatomedin. XXIII. Molecular regulation of IGF-I by amino acid availability in cultured hepatocytesDiabetes199140 95 101 1:CAS:528:DyaK3MXhs1aqtbo%3D https://doi.org/10.2337/diab.40.1.95 1901809
- Chwalbiñska-MonetaJEffect of creatine supplementation on aerobic performance and anaerobic capacity in elite rowers in the course of endurance trainingInt J Sport Nutr Exerc Metab200313 173 183 12945828
- GraefJSmithAKendallKFukudaDMoonJBeckTCramerJStoutJThe effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trialJ Int Soc Sports Nutr20096 18 2780977 https://doi.org/10.1186/1550-2783-6-18 19909536
- ThompsonCKempGSandersonADixonRStylesPTaylorDRaddaGEffect of creatine on aerobic and anaerobic metabolism in skeletal muscle in swimmersBr J Sports Med199630 222 225 1332335 1:STN:280:DyaK2s%2FksVSntg%3D%3D https://doi.org/10.1136/bjsm.30.3.222 8889115
- NelsonAArnallDKokkonenJDayREvansJMuscle glycogen supercompensation is enhanced by prior creatine supplementationMed Sci Sports Exerc200133 1096 1100 1:CAS:528:DC%2BD3MXlsFSqsbw%3D https://doi.org/10.1097/00005768-200107000-00005 11445755
- SewellDRobinsonTGreenhaffPCreatine supplementation does not affect human skeletal muscle glycogen content in the absence of prior exerciseJ Appl Physiol2008104 508 512 1:CAS:528:DC%2BD1cXjtleltLs%3D https://doi.org/10.1152/japplphysiol.00787.2007 18032580
- Op 't EijndeBUrsoBRichterEAGreenhaffPLHespelPEffect of oral creatine supplementation on human muscle GLUT4 protein content after immobilizationDiabetes200150 18 23 https://doi.org/10.2337/diabetes.50.1.18 11147785
- BassitRAPinheiroCHVitzelKFSproesserAJSilveiraLRCuriREffect of short-term creatine supplementation on markers of skeletal muscle damage after strenuous contractile activityEur J Appl Physiol2010108 945 955 1:CAS:528:DC%2BC3cXotVOqs7w%3D https://doi.org/10.1007/s00421-009-1305-1 19956970
- CookeMBRybalkaEWilliamsADCribbPJHayesACreatine supplementation enhances muscle force recovery after eccentrically-induced muscle damage in healthy individualsJ Int Soc Sports Nutr20096 13 2697134 https://doi.org/10.1186/1550-2783-6-13 19490606
- LawlerJMBarnesWSWuGSongWDemareeSDirect antioxidant properties of creatineBiochem Biophys Res Commun2002290 47 52 1:CAS:528:DC%2BD38XhsFCisg%3D%3D https://doi.org/10.1006/bbrc.2001.6164 11779131
- SestiliPMartinelliCBraviGPiccoliGCurciRBattistelliMFalcieriEAgostiniDGioacchiniAMStocchiVCreatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activityFree Radic Biol Med200640 837 849 1:CAS:528:DC%2BD28XitVartrg%3D https://doi.org/10.1016/j.freeradbiomed.2005.10.035 16520236
- RahimiRCreatine supplementation decreases oxidative DNA damage and lipid peroxidation induced by a single bout of resistance exerciseJ Strength Cond Res201125 3448 3455 https://doi.org/10.1519/JSC.0b013e3182162f2b 22080314
- SculthorpeNGraceFJonesPFletcherIThe effect of short-term creatine loading on active range of movementAppl Physiol Nutr Metab201035 507 511 1:CAS:528:DC%2BC3cXpsFyiur4%3D https://doi.org/10.1139/H10-036 20725117
- HileAAndersonJFialaKStevensonJCasaDMareshCCreatine supplementation and anterior compartment pressure during exercise in the heat in dehydrated menJ Athl Train200641 30 35 1421498 16619092
- HammettSWallMEdwardsTSmithADietary supplementation of creatine monohydrate reduces the human fMRI BOLD signalNeurosci Lett2010479 201 205 1:CAS:528:DC%2BC3cXosVGrurk%3D https://doi.org/10.1016/j.neulet.2010.05.054 20570601
- D'AnciKEAllenPJKanarekRBA potential role for creatine in drug abuse?Mol Neurobiol201144 136 41 https://doi.org/10.1007/s12035-011-8176-2 21399936
- RawsonESVeneziaACUse of creatine in the elderly and evidence for effects on cognitive function in young and oldAmino Acids201140 1349 1362 1:CAS:528:DC%2BC3MXkvFWqt74%3D https://doi.org/10.1007/s00726-011-0855-9 21394604
- BealMFNeuroprotective effects of creatineAmino Acids201140 1305 1313 1:CAS:528:DC%2BC3MXkvFWqt7g%3D https://doi.org/10.1007/s00726-011-0851-0 21448659
- BraissantOHenryHBéardEUldryJCreatine deficiency syndromes and the importance of creatine synthesis in the brainAmino Acids201140 1315 1324 1:CAS:528:DC%2BC3MXkvFWqtrc%3D https://doi.org/10.1007/s00726-011-0852-z 21390529
- MetzlJDSmallELevineSRGershelJCCreatine use among young athletesPediatrics2001108 421 425 1:STN:280:DC%2BD3MvjvVWmug%3D%3D https://doi.org/10.1542/peds.108.2.421 11483809
- EvansMWNdetanHPerkoMWilliamsRWalkerCDietary supplement use by children and adolescents in the United States to Enhance sport performance: results of the national health interview surveyJ Prim Prev201233 3 12 https://doi.org/10.1007/s10935-012-0261-4 22297456
- UnnithanVBVeehofSHVellaCAKernMIs there a physiologic basis for creatine use in children and adolescents?J Strength Cond Res200115 524 528 1:STN:280:DC%2BD3MnotVGlsQ%3D%3D 11726268
- WilloughbyDSRoseneJEffects of oral creatine and resistance training on myosin heavy chain expressionMed Sci Sports Exerc200133 1674 1681 1:CAS:528:DC%2BD3MXnvVCksLw%3D https://doi.org/10.1097/00005768-200110000-00010 11581551
- SaleCHarrisRCFloranceJKumpsASanvuraRPoortmansJRUrinary creatine and methylamine excretion following 4 x 5 g x day(-1) or 20 x 1 g x day(-1) of creatine monohydrate for 5 daysJ Sports Sci200927 759 766 https://doi.org/10.1080/02640410902838237 19437189
- SyrotuikDGBellGJAcute creatine monohydrate supplementation: a descriptive physiological profile of responders vs. nonrespondersJ Strength Cond Res200418 610 617 15320650
- GreenhaffPLBodinKSoderlundKHultmanEEffect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesisAm J Physiol1994266 E725 E730 1:CAS:528:DyaK2cXktleqt7s%3D 8203511
- GangulySJayappaSDashAKEvaluation of the stability of creatine in solution prepared from effervescent creatine formulationsAAPS PharmSciTech20034 E25 https://doi.org/10.1208/pt040225 12916907
- JägerRHarrisRCPurpuraMFrancauxMComparison of new forms of creatine in raising plasma creatine levelsJ Int Soc Sports Nutr20074 17 2206055 https://doi.org/10.1186/1550-2783-4-17 17997838
- JägerRMetzgerJLautmannKShushakovVPurpuraMGeissKMaassenNThe effects of creatine pyruvate and creatine citrate on performance during high intensity exerciseJ Int Soc Sports Nutr20085 4 2276184 https://doi.org/10.1186/1550-2783-5-4 18269769
- JägerRPurpuraMShaoAInoueTKreiderRBAnalysis of the efficacy, safety, and regulatory status of novel forms of creatineAmino Acids201140 1369 83 3080578 https://doi.org/10.1007/s00726-011-0874-6 21424716
- GuffordBTSriraghavanKMillerNMillerDGuXVennerstromJRobinsonDPhysicochemical characterization of creatine N-methylguanidinium saltsJournal of Dietary Supplements20107 240 252 https://doi.org/10.3109/19390211.2010.491507 22432515
- PerskyAMBrazeauGAHochhausGPharmacokinetics of the dietary supplement creatineClin Pharmacokinet200342 557 574 1:CAS:528:DC%2BD3sXmtVGmurk%3D https://doi.org/10.2165/00003088-200342060-00005 12793840
- SpillaneMSchochRCookeMHarveyTGreenwoodMKreiderRWilloughbyDSThe effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levelsJ Int Soc Sports Nutr20096 6 2649889 https://doi.org/10.1186/1550-2783-6-6 19228401
- KnopKHoogenboomRFischerDSchubertUSPoly(ethylene glycol) in drug delivery: pros and cons as well as potential alternativesAngew Chem Int Ed Engl201049 6288 6308 1:CAS:528:DC%2BC3cXhtVOqtLbN https://doi.org/10.1002/anie.200902672 20648499
- CamicCLHendrixCRHoushTJZunigaJMMielkeMJohnsonGOSchmidtRJHoushDJThe effects of polyethylene glycosylated creatine supplementation on muscular strength and powerJ Strength Cond Res201024 3343 3351 https://doi.org/10.1519/JSC.0b013e3181fc5c5c 21068676
- HerdaTJBeckTWRyanEDSmithAEWalterAAHartmanMJStoutJRCramerJTEffects of creatine monohydrate and polyethylene glycosylated creatine supplementation on muscular strength, endurance, and power outputJ Strength Cond Res200923 818 826 https://doi.org/10.1519/JSC.0b013e3181a2ed11 19387397
- SteengeGRLambourneJCaseyAMacdonaldIAGreenhaffPLStimulatory effect of insulin on creatine accumulation in human skeletal muscleAm J Physiol1998275 E974 E979 1:CAS:528:DyaK1MXhsFKjuw%3D%3D 9843739
- SteengeGSimpsonEGreenhaffPProtein- and carbohydrate-induced augmentation of whole body creatine retention in humansJ Appl Physiol200089 1165 1171 1:CAS:528:DC%2BD3cXntV2jtLs%3D 10956365
- OlsenSAagaardPKadiFTufekovicGVerneyJOlesenJLSuettaCKjaerMCreatine supplementation augments the increase in satellite cell and myonuclei number in human skeletal muscle induced by strength trainingJ Physiol2006573 525 534 1779717 1:CAS:528:DC%2BD28XmtVait74%3D https://doi.org/10.1113/jphysiol.2006.107359 16581862
- WalshALGonzalezAMRatamessNAKangJHoffmanJRImproved time to exhaustion following ingestion of the energy drink Amino ImpactJ Int Soc Sports Nutr20107 14 2861014 https://doi.org/10.1186/1550-2783-7-14 20398312
- YoshizumiWTsourounisCEffects of creatine supplementation on renal functionJ Herb Pharmacother20044 1 7 1:CAS:528:DC%2BD2cXjs1Srs70%3D https://doi.org/10.1080/J157v04n01_01 15273072
- ThorsteinsdottirBGrandeJGarovicVAcute renal failure in a young weight lifter taking multiple food supplements, including creatine monohydrateJ Ren Nutr200616 341 345 https://doi.org/10.1053/j.jrn.2006.04.025 17046619
- PlineKSmithCThe effect of creatine intake on renal functionAnn Pharmacother200539 1093 1096 1:CAS:528:DC%2BD2MXltlOns7s%3D https://doi.org/10.1345/aph.1E628 15886291
- PoortmansJFrancauxMAdverse effects of creatine supplementation: fact or fiction?Sports Med200030 155 170 1:STN:280:DC%2BD3cvks1ynuw%3D%3D https://doi.org/10.2165/00007256-200030030-00002 10999421
- BizzariniEDe AngelisLIs the use of oral creatine supplementation safe?J Sports Med Phys Fitness200444 411 416 1:CAS:528:DC%2BD2MXjvF2lsLY%3D 15758854
- KimHJKimCKCarpentierAPoortmansJRStudies on the safety of creatine supplementationAmino Acids201140 1409 1418 1:CAS:528:DC%2BC3MXkvFWqt7w%3D https://doi.org/10.1007/s00726-011-0878-2 21399917
- TarnopolskyMZimmerAPaikinJSafdarAAboudAPearceERoyBDohertyTCreatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adultsPLoS One20072 e991 1994592 https://doi.org/10.1371/journal.pone.0000991 17912368
- CornelissenVADefoorJGStevensASchepersDHespelPDecramerMMortelmansLDobbelsFVanhaeckeJFagardRHVanheesLEffect of creatine supplementation as a potential adjuvant therapy to exercise training in cardiac patients: a randomized controlled trialClin Rehabil201024 988 999 1:STN:280:DC%2BC3cbisFyntw%3D%3D https://doi.org/10.1177/0269215510367995 20576665
- SchillingBStoneMUtterAKearneyJJohnsonMCoglianeseRSmithLO'BryantHFryAStarksM et al Creatine supplementation and health variables: a retrospective studyMed Sci Sports Exerc200133 183 188 1:CAS:528:DC%2BD3MXhtl2ntb4%3D https://doi.org/10.1097/00005768-200102000-00002 11224803
- DalboVRobertsMStoutJKerksickCPutting to rest the myth of creatine supplementation leading to muscle cramps and dehydrationBr J Sports Med200842 567 573 1:STN:280:DC%2BD1cvjtVKksA%3D%3D https://doi.org/10.1136/bjsm.2007.042473 18184753
- WatsonGCasaDFialaKHileARotiMHealeyJArmstrongLMareshCCreatine use and exercise heat tolerance in dehydrated menJ Athl Train200641 18 29 1421496 16619091
- LopezRCasaDMcDermottBGanioMArmstrongLMareshCDoes creatine supplementation hinder exercise heat tolerance or hydration status? A systematic review with meta-analysesJ Athl Train200944 215 223 2657025 https://doi.org/10.4085/1062-6050-44.2.215 19295968
- HadjicharalambousMKilduffLPitsiladisYBrain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementationJ Int Soc Sports Nutr20085 14 2570654 https://doi.org/10.1186/1550-2783-5-14 18826587