Search in:

Advanced search

Journal of the International Society of Sports Nutrition Volume 13, 2016 - Issue 1

Submit an article Journal homepage

Open access

877

Views

CrossRef citations to date

Altmetric

Research Article

Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use

Lem Taylor1 Department of Exercise and Sport Science, Human Performance Lab & Exercise Biochemistry LabUniversity of Mary Hardin-BaylorBeltonTXUSACorrespondence[email protected]

Petey Mumford2 School of KinesiologyAuburn UniversityAuburnALUSA

Mike Roberts2 School of KinesiologyAuburn UniversityAuburnALUSA

Sara Hayward1 Department of Exercise and Sport Science, Human Performance Lab & Exercise Biochemistry LabUniversity of Mary Hardin-BaylorBeltonTXUSA

Jacy Mullins1 Department of Exercise and Sport Science, Human Performance Lab & Exercise Biochemistry LabUniversity of Mary Hardin-BaylorBeltonTXUSA

Stacie Urbina1 Department of Exercise and Sport Science, Human Performance Lab & Exercise Biochemistry LabUniversity of Mary Hardin-BaylorBeltonTXUSA

Colin Wilborn1 Department of Exercise and Sport Science, Human Performance Lab & Exercise Biochemistry LabUniversity of Mary Hardin-BaylorBeltonTXUSA

show all

Article: 2 | Published online: 01 Apr 2022

Cite this article
https://doi.org/10.1186/s12970-016-0113-3
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

ZhengXQYeCXKatoMCrozierAAshiharaHTheacrine (1,3,7,9-tetramethyluric acid) synthesis in leaves of a Chinese tea, kucha (Camellia assamica var. kucha)Phytochemistry200260 2 129 34 12009315 https://doi.org/10.1016/S0031-9422(02)00086-9 1:CAS:528:DC%2BD38XjsFKrtL0%3D
PubMed Web of Science ®Google Scholar
HabowskiSMSandrockJEKediaAWZiegenfussTThe effects of TeacrineTM, a nature-identical purine alkaloid, on subjective measures of cognitive function, psychometric and hemodynamic indices in healthy humans: a randomized, double-blinded crossover pilot trialJ Int Soc Sports Nutr201411 1 1 2 https://doi.org/10.1186/1550-2783-11-1
Google Scholar
FeducciaAAWangYSimmsJAYiHYLiRBjeldanesL et al Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptorsPharmacol Biochem Behav2012102 2 241 8 22579816 https://doi.org/10.1016/j.pbb.2012.04.014 1:CAS:528:DC%2BC38XptVKgsr4%3D
PubMed Web of Science ®Google Scholar
WangYYangXZhengXLiJYeCSongXTheacrine, a purine alkaloid with anti-inflammatory and analgesic activitiesFitoterapia201081 6 627 31 20227468 https://doi.org/10.1016/j.fitote.2010.03.008 1:CAS:528:DC%2BC3cXpt12hurk%3D
PubMed Web of Science ®Google Scholar
LiSBLiYFMaoZFHuHHOuyangSHWuYP et al Differing chemical compositions of three teas may explain their different effects on acute blood pressure in spontaneously hypertensive ratsJ Sci Food Agric201595 6 1236 42 25043720 https://doi.org/10.1002/jsfa.6811 1:CAS:528:DC%2BC2cXht1SksrnF
PubMedGoogle Scholar
OutlawJWilbornCSmithAUrbinaSHaywardSFosterC et al Effects of ingestion of a commercially available thermogenic dietary supplement on resting energy expenditure, mood state and cardiovascular measuresJ Int Soc Sports Nutr201310 1 25 23627832 3651299 https://doi.org/10.1186/1550-2783-10-25 1:CAS:528:DC%2BC3sXotFCksL0%3D
PubMed Web of Science ®Google Scholar
ChenYMLiuYLiuYHWangXGuanKZhuHLHigher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adultsInt J Obes201539 3 465 71 https://doi.org/10.1038/ijo.2014.158 1:CAS:528:DC%2BC2cXhsFyks77E
Google Scholar
GoldsteinERZiegenfussTKalmanDKreiderRCampbellBWilbornC et al International society of sports nutrition position stand: caffeine and performanceJ Int Soc Sports Nutr20107 1 5 20205813 2824625 https://doi.org/10.1186/1550-2783-7-5 1:CAS:528:DC%2BC3cXksFensb8%3D
PubMedGoogle Scholar
VogelRMJoyJMFalconePHMosmanMMKimMPMoonJRConsuming a multi-ingredient thermogenic supplement for 28 days is apparently safe in healthy adultsFood Nutr Res201559 27999 26205229 https://doi.org/10.3402/fnr.v59.27999
PubMed Web of Science ®Google Scholar
ChurchDDHoffmanJRLaMonicaMBRiffeJJHoffmanMWBakerKM et al The effect of an acute ingestion of Turkish coffee on reaction time and time trial performanceJ Int Soc Sports Nutr201512 37 26445565 4595106 https://doi.org/10.1186/s12970-015-0098-3
PubMed Web of Science ®Google Scholar
LeeKAHicksGNino-MurciaGValidity and reliability of a scale to assess fatiguePsychiatry Res199136 3 291 8 2062970 https://doi.org/10.1016/0165-1781(91)90027-M 1:STN:280:DyaK3M3ovVOjtA%3D%3D
PubMed Web of Science ®Google Scholar
KruskallLJCampbellWWEvansWJThe Yale Physical Activity Survey for older adults: predictions in the energy expenditure due to physical activityJ Am Diet Assoc2004104 8 1251 7 15281043 https://doi.org/10.1016/j.jada.2004.05.207
PubMedGoogle Scholar
ZiegenfussTNHabowskiSMLemieuxRSandrockJEKediaAWKerksickCM et al Effects of a dietary supplement on golf drive distance and functional indices of golf performanceJ Int Soc Sports Nutr201512 1 4 25632274 4308854 https://doi.org/10.1186/s12970-014-0065-4 1:CAS:528:DC%2BC2MXjtVCktrc%3D
PubMedGoogle Scholar
TrevisanatoSIKimYITea and healthNutr Rev200058 1 1 10 10697388 https://doi.org/10.1111/j.1753-4887.2000.tb01818.x 1:STN:280:DC%2BD3c7mt1Cqsg%3D%3D
PubMedGoogle Scholar
WeisburgerJHTea and health: a historical perspectiveCancer Lett1997114 1-2 315 7 9103320 https://doi.org/10.1016/S0304-3835(97)04691-0 1:CAS:528:DyaK2sXit1eht7c%3D
PubMedGoogle Scholar
SarmaDNBarrettMLChavezMLGardinerPKoRMahadyGB et al Safety of green tea extracts: a systematic review by the US PharmacopeiaDrug Saf200831 6 469 84 18484782 https://doi.org/10.2165/00002018-200831060-00003
PubMed Web of Science ®Google Scholar
RiksenNPRongenGASmitsPAcute and long-term cardiovascular effects of coffee: implications for coronary heart diseasePharmacol Ther2009121 2 185 91 19049813 https://doi.org/10.1016/j.pharmthera.2008.10.006 1:CAS:528:DC%2BD1MXitVOks7w%3D
PubMed Web of Science ®Google Scholar
XuJKKuriharaHZhaoLYaoXSTheacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in miceJ Asian Nat Prod Res20079 6-8 665 72 17943563 https://doi.org/10.1080/10286020601103155 1:CAS:528:DC%2BD2sXhtFOjtr7K
PubMedGoogle Scholar
SatohSMatsumuraHHayaishiOInvolvement of adenosine A2A receptor in sleep promotionEur J Pharmacol1998351 2 155 62 9686998 https://doi.org/10.1016/S0014-2999(98)00302-1 1:CAS:528:DyaK1cXktFGmtLs%3D
PubMedGoogle Scholar
SatohSMatsumuraHKoikeNTokunagaYMaedaTHayaishiORegion-dependent difference in the sleep-promoting potency of an adenosine A2A receptor agonistEur J Neurosci199911 5 1587 97 10215911 https://doi.org/10.1046/j.1460-9568.1999.00569.x 1:STN:280:DyaK1M3jtl2nuw%3D%3D
PubMedGoogle Scholar
AliM Pharmacognosy (pharmacognosy and phytochemistry)2008 New Delhi CBS Publishers & Distributors Pvt. Ltd
Google Scholar
IkedaIImasatoYSasakiENakayamaMNagaoHTakeoT et al Tea catechins decrease micellar solubility and intestinal absorption of cholesterol in ratsBiochim Biophys Acta19921127 2 141 6 1643098 https://doi.org/10.1016/0005-2760(92)90269-2 1:CAS:528:DyaK38XltlSisrg%3D
PubMedGoogle Scholar
MaronDJLuGPCaiNSWuZGLiYHChenH et al Cholesterol-lowering effect of a theaflavin-enriched green tea extract: a randomized controlled trialArch Intern Med2003163 12 1448 53 12824094 https://doi.org/10.1001/archinte.163.12.1448 1:CAS:528:DC%2BD3sXls1Gjtbg%3D
PubMed Web of Science ®Google Scholar
Westerterp-PlantengaMSLejeuneMPKovacsEMBody weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementationObes Res200513 7 1195 204 16076989 https://doi.org/10.1038/oby.2005.142 1:CAS:528:DC%2BD2MXhtVSltrrL
PubMedGoogle Scholar
AnayaALCruz-OrtegaRWallerGRMetabolism and ecology of purine alkaloidsFront Biosci200611 2354 70 16720319 https://doi.org/10.2741/1975 1:CAS:528:DC%2BD28XlvVags7o%3D
PubMedGoogle Scholar
AshiharaHSanoHCrozierACaffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineeringPhytochemistry200869 4 841 56 18068204 https://doi.org/10.1016/j.phytochem.2007.10.029 1:CAS:528:DC%2BD1cXhslGrsrc%3D
PubMed Web of Science ®Google Scholar
KovacsEMLejeuneMPNijsIWesterterp-PlantengaMSEffects of green tea on weight maintenance after body-weight lossBr J Nutr200491 3 431 7 15005829 https://doi.org/10.1079/BJN20041061 1:CAS:528:DC%2BD2cXisVKhtLk%3D
PubMed Web of Science ®Google Scholar
HurselRViechtbauerWWesterterp-PlantengaMSThe effects of green tea on weight loss and weight maintenance: a meta-analysisInt J Obes200933 9 956 61 https://doi.org/10.1038/ijo.2009.135 1:CAS:528:DC%2BD1MXhtFajsL%2FF
PubMed Web of Science ®Google Scholar

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Safety of TeaCrine®, a non-habituating, naturally-occurring purine alkaloid over eight weeks of continuous use

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date