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Journal of the International Society of Sports Nutrition Volume 17, 2020 - Issue 1

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Research Article

The addition of an amylopectin/chromium complex to branched-chain amino acids enhances muscle protein synthesis in rat skeletal muscle

James R. Komorowski1 Research and Development DepartmentNutrition 21 LLC10577PurchaseNYUSACorrespondence[email protected]

https://orcid.org/0000-0003-2399-838X

Sara Perez Ojalvo1 Research and Development DepartmentNutrition 21 LLC10577PurchaseNYUSA

Sarah Sylla1 Research and Development DepartmentNutrition 21 LLC10577PurchaseNYUSA

Hakki Tastan2 Division of Biology, Faculty of ScienceGazi University06100AnkaraTurkey

Cemal Orhan3 Department of Animal Nutrition and Nutritional Disorders, Faculty of Veterinary MedicineFirat University23119ElazigTurkey

Mehmet Tuzcu4 Division of Biology, Faculty of ScienceFirat University23119ElazigTurkey

Nurhan Sahin3 Department of Animal Nutrition and Nutritional Disorders, Faculty of Veterinary MedicineFirat University23119ElazigTurkey

Kazim Sahin3 Department of Animal Nutrition and Nutritional Disorders, Faculty of Veterinary MedicineFirat University23119ElazigTurkey

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Article: 26 | Published online: 01 Apr 2022

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https://doi.org/10.1186/s12970-020-00355-8
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PhilpAHargreavesMBaarKMore than a store: regulatory roles for glycogen in skeletal muscle adaptation to exerciseAm J Physiol Endocrinol Metab2012302 E1343 E1351 1:CAS:528:DC%2BC38XhtVGlsr7E 22395109 https://doi.org/10.1152/ajpendo.00004.2012
PubMed Web of Science ®Google Scholar
McGloryCvan VlietSStokesTMittendorferBPhillipsSMThe impact of exercise and nutrition on the regulation of skeletal muscle massJ Physiol2019597 5 1251 1258 1:CAS:528:DC%2BC1cXhsVeiu73M 30010196 https://doi.org/10.1113/JP275443
PubMedGoogle Scholar
IvyJLDingZHwangHCialdella-KamLCMorrisonPJPost exercise carbohydrate-protein supplementation: phosphorylation of muscle proteins involved in glycogen synthesis and protein translationAmino Acids200835 1 89 97 1:CAS:528:DC%2BD1cXmslWjtb0%3D 18163180 https://doi.org/10.1007/s00726-007-0620-2
PubMedGoogle Scholar
WangWDingZSolaresGJChoiSMWangBYoonAFarrarRPIvyJLCo-ingestion of carbohydrate and whey protein increases fasted rates of muscle protein synthesis immediately after resistance exercise in ratsPLoS One201712 3 28296942 5351968 https://doi.org/10.1371/journal.pone.0173809 1:CAS:528:DC%2BC2sXht1WjurfK
PubMedGoogle Scholar
BoutryCEl-KadiSWSuryawanAWheatleySMOrellanaRAKimballSR et al Leucine pulses enhance skeletal muscle protein synthesis during continuous feeding in neonatal pigsAm J Physiol Endocrinol Metab2013305 E620 E631 1:CAS:528:DC%2BC3sXhs1SqsLfP 23839523 3761169 https://doi.org/10.1152/ajpendo.00135.2013
PubMed Web of Science ®Google Scholar
FalavignaGAlves de AraújoJJrRogeroMMPiresISPedrosaRGMartinsEJrAlves de CastroITirapeguiJEffects of diets supplemented with branched-chain amino acids on the performance and fatigue mechanisms of rats submitted to prolonged physical exerciseNutrients20124 11 1767 1780 1:CAS:528:DC%2BC38XhvVagsrzM 23201847 3509520 https://doi.org/10.3390/nu4111767
PubMedGoogle Scholar
YoshidaTKakizawaSTotsukaYSugimotoMMiuraSKumagaiHEffect of endurance training and branched-chain amino acids on the signaling for muscle protein synthesis in CKD model rats fed a low-protein dietAm J Physiol Renal Physiol2017313 3 F805 F814 1:CAS:528:DC%2BC1cXhsVOisrc%3D 28701315 https://doi.org/10.1152/ajprenal.00592.2015
PubMedGoogle Scholar
ShimomuraYMurakamiTNakaiNNagasakiMHarrisRAExercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exerciseJ Nutr2004134 6 Suppl 1583S 1587S 1:CAS:528:DC%2BD2cXltVSksL4%3D 15173434 https://doi.org/10.1093/jn/134.6.1583S
PubMedGoogle Scholar
TajiriKShimizuYBranched-chain amino acids in liver diseasesTransl Gastroenterol Hepatol201830 3 47 https://doi.org/10.21037/tgh.2018.07.06
Web of Science ®Google Scholar
BioloGFlemingRYMaggiSPWolfeRRTransmembrane transport and intracellular kinetics of amino acids in human skeletal muscleAm J Physiol Endocrinol Metab1995268 1 Pt 1 E75 E84 1:CAS:528:DyaK2MXktFWqs7k%3D https://doi.org/10.1152/ajpendo.1995.268.1.E75
Web of Science ®Google Scholar
GonçalvesNGCavalettiSHPasqualucciCAArruda MartinsMLinCJFructose ingestion impairs expression of genes involved in skeletal muscle's adaptive response to aerobic exerciseGenes Nutr201712 33 29234478 5721527 https://doi.org/10.1186/s12263-017-0588-9 1:CAS:528:DC%2BC2sXhvFers7vN
PubMedGoogle Scholar
MuñozVRGasparRCKugaGKda RochaALCrisolBMBotezelliJDBaptistaILMekaryRAda SilvaASRCintraDEde MouraLPRopelleERPauliJRExercise increases rho-kinase activity and insulin signaling in skeletal muscleJ Cell Physiol2018233 6 4791 4800 29219181 https://doi.org/10.1002/jcp.26278 1:CAS:528:DC%2BC1cXovVWqtQ%3D%3D
PubMedGoogle Scholar
Churchward-VenneTABurdNAMitchellCJ et al Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in menJ Physiol2012590 2751 2765 1:CAS:528:DC%2BC38XhtFGrsL%2FF 22451437 3424729 https://doi.org/10.1113/jphysiol.2012.228833
PubMed Web of Science ®Google Scholar
KandaAtsushiNakayamaKyosukeSanbongiChiakiNagataMasashiIkegamiShujiItohHiroyukiEffects of Whey, Caseinate, or Milk Protein Ingestion on Muscle Protein Synthesis after ExerciseNutrients20168 6 339 4924180 https://doi.org/10.3390/nu8060339 1:CAS:528:DC%2BC2sXmvVOjsbc%3D
PubMed Web of Science ®Google Scholar
BorsheimECreeMGTiptonKDElliottTAAarslandAWolfeRREffect of carbohydrate intake on net muscle protein synthesis during recovery from resistance exerciseJ Appl Physiol200496 2 674 678 1:CAS:528:DC%2BD2cXhsVyjsLk%3D 14594866 https://doi.org/10.1152/japplphysiol.00333.2003
PubMedGoogle Scholar
WolfeRREffects of insulin on muscle tissueCurr Opin Clin Nutr MetabCare20003 67 71 1:CAS:528:DC%2BD3cXos1Ojtw%3D%3D https://doi.org/10.1097/00075197-200001000-00011
PubMedGoogle Scholar
ZiegenfussTNLopezHLKediaAHabowskiSMSandrockJERaubBKerksickCMFerrandoAAEffects of an amylopectin and chromium complex on the anabolic response to a suboptimal dose of whey proteinJISSN201714 6 1:STN:280:DC%2BC1c3mtlyqsQ%3D%3D 28194093
PubMedGoogle Scholar
SchiaffinoSDyarKACiciliotSBlaauwBSandriMMechanisms regulating skeletal muscle growth and atrophyFEBS J2013280 4294 4314 1:CAS:528:DC%2BC3sXht1ymu7nK 23517348 https://doi.org/10.1111/febs.12253
PubMed Web of Science ®Google Scholar
KimballSRShantzLMHoretskyRLJeffersonLSLeucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6J Biol Chem1999274 17 11647 11652 1:CAS:528:DyaK1MXislGmu7g%3D 10206976 https://doi.org/10.1074/jbc.274.17.11647
PubMedGoogle Scholar
WullschlegerSLoewithRHallMNTOR signaling in growth and metabolismCell.2006124 3 471 484 1:CAS:528:DC%2BD28Xhslaqs74%3D 16469695 https://doi.org/10.1016/j.cell.2006.01.016
PubMed Web of Science ®Google Scholar
NortonLEWilsonGJLaymanDKMoultonCJGarlickPJLeucine content of dietary proteins is a determinant of postprandial skeletal muscle protein synthesis in adult ratsNutr Metabol20129 67 1:CAS:528:DC%2BC38XhvVSiu7%2FF https://doi.org/10.1186/1743-7075-9-67
Google Scholar
WangHKruszewskiABrautiganDLCellular chromium enhances activation of insulin receptor kinaseBiochemistry.200544 8167 8175 1:CAS:528:DC%2BD2MXktVKls7k%3D 15924436 https://doi.org/10.1021/bi0473152
PubMed Web of Science ®Google Scholar
CefaluWTWangZQZhangXH et al Oral chromium picolinate improves carbohydrate and lipid metabolism and enhances skeletal muscle glut-4 translocation in obese, hyperinsulinemic (JCR-LA corpulent) ratsJ Nutr2002132 1107 1114 1:CAS:528:DC%2BD38XksFWns7g%3D 12042418 https://doi.org/10.1093/jn/132.6.1107
PubMed Web of Science ®Google Scholar
SahinKTuzcuMOrhanCSahinNKucukOOzercanIHJuturuVKomorowskiJRAnti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocinBr J Nutr2013110 2 197 205 1:CAS:528:DC%2BC3sXpsFGrsb0%3D 23211098 https://doi.org/10.1017/S0007114512004850
PubMedGoogle Scholar
ChenGGaoZChuWCaoZLiCZhaoHEffects of chromium Picolinate on fat deposition, activity and genetic expression of lipid metabolism-related enzymes in 21 day old Ross broilersAsian-Australas J Anim Sci201831 4 569 575 28830127 https://doi.org/10.5713/ajas.17.0289 1:CAS:528:DC%2BC1MXhvVeis74%3D
PubMedGoogle Scholar
RegmiPRMatteJJVan KempenTATGZijlstraRT(2010). Starch chemistry affects kinetics of glucose absorption and insulin response in swineLivest Sci2010134 1 44 46 https://doi.org/10.1016/j.livsci.2010.06.092
Google Scholar
BarkTMcNurlanMLangCGarlickPJIncreased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in miceAm J Phys1998275 E118 EE23 1:CAS:528:DyaK1cXkvVOntLk%3D
Google Scholar
TakachEO'SheaTLiuH2014. High-throughput quantitation of amino acids in rat and mouse biological matrices using stable isotope labeling and UPLC-MS/MS analysisJ Chromatogr B Analyt Technol Biomed Life Sci20141 964 180 190 https://doi.org/10.1016/j.jchromb.2014.04.043 1:CAS:528:DC%2BC2cXotlyls7Y%3D
Google Scholar
SahinKPalaRTuzcuMOzdemirOOrhanCSahinNJuturuVCurcumin prevents muscle damage by regulating NF-κB and Nrf2 pathways and improves performance: an in vivo modelJ Inflamm Res20169 147 154 1:CAS:528:DC%2BC1cXnsFGgu7w%3D 27621662 5010171 https://doi.org/10.2147/JIR.S110873
PubMed Web of Science ®Google Scholar
AnthonyJCAnthonyTGKimballSRVaryTCJeffersonLSOrally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formationJ Nutr2000130 139 145 1:CAS:528:DC%2BD3cXhtVSmsbY%3D 10720160 https://doi.org/10.1093/jn/130.2.139
PubMed Web of Science ®Google Scholar
AnthonyTGMcDanielBJKnollPBunpoPPaulGLMcNurlanMAFeeding meals containing soy or whey protein after exercise stimulates protein synthesis and translation initiation in the skeletal muscle of male ratsNutr.2007137 2 357 362 1:CAS:528:DC%2BD2sXhsVWjtbY%3D https://doi.org/10.1093/jn/137.2.357
Google Scholar
RennieMJBohéJSmithKWackerhageHGreenhaffPBranched-chain amino acids as fuels and anabolic signals in human muscleJ Nutr2006136 1 Suppl 264S 268S 1:CAS:528:DC%2BD28XivFSisQ%3D%3D 16365095 https://doi.org/10.1093/jn/136.1.264S
PubMedGoogle Scholar
KomorowskiJPerez OjalvoSSahinNTastanHSahinKThe effect of the addition of an amylopectin/chromium complex to increasing doses of whey protein on muscle protein synthesis in ratsJISSN.201714 Suppl 2 P44
Google Scholar
WolfeRRBranched-chain amino acids and muscle protein synthesis in humans: myth or reality?JISSN.201714 30 28852372
PubMedGoogle Scholar
JackmanSRWitardOCPhilpAWallisGABaarKTiptonKDBranched-chain amino acid ingestion stimulates muscle Myofibrillar protein synthesis following resistance exercise in humansFront Physiol20178 390 28638350 5461297 https://doi.org/10.3389/fphys.2017.00390
PubMedGoogle Scholar
BouitbirJSanveeGMPanajatovicMVSinghFGingras ACKSGygiSPMechanisms of statin-associated skeletal muscle-associated symptomsPharmacol Res2019154 104201 30877064 https://doi.org/10.1016/j.phrs.2019.03.010 1:CAS:528:DC%2BC1MXhtVKju7nL
PubMedGoogle Scholar
OgasawaraRikiJensenThomas E.GoodmanCraig A.HornbergerTroy A.Resistance Exercise-Induced HypertrophyExercise and Sport Sciences Reviews201947 3 188 194 30870215 https://doi.org/10.1249/JES.0000000000000189
PubMedGoogle Scholar
KimDSarbassovDAliSKingJLatekRErdjument-BromageHTempstPSabatiniDmTOR interacts with raptor to form a nutrientsensitive complex that signals to the cell growth machineryCell.2002110 163 175 1:CAS:528:DC%2BD38XlvV2htr4%3D 12150925 https://doi.org/10.1016/S0092-8674(02)00808-5
PubMed Web of Science ®Google Scholar
MorrisonPJHaraDDingZIvyJLAdding protein to a carbohydrate supplement provided after endurance exercise enhances 4E-BP1 and RPS6 signaling in skeletal muscleJ Appl Physiol2008104 4 1029 1036 1:CAS:528:DC%2BD1cXlsVensLg%3D 18239077 https://doi.org/10.1152/japplphysiol.01173.2007
PubMedGoogle Scholar
DreyerHCDrummondMJPenningsBFujitaSGlynnELChinkesDL et al Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscleAm J Physiol Endocrinol Metab2008294 2 E392 E400 1:CAS:528:DC%2BD1cXit1yktbc%3D 18056791 https://doi.org/10.1152/ajpendo.00582.2007
PubMed Web of Science ®Google Scholar
ProudCRole of mTOR signaling in the control of translation initiation and elongation by nutrientsCurr Top Microbiol Immunol2004279 215 244 1:CAS:528:DC%2BD3sXpt1Skurg%3D 14560960
PubMed Web of Science ®Google Scholar
SmithGYoshinoJStromsdorferKLKleinSJMagkosFReedsDNKleinSMittendorferBProtein ingestion induces muscle insulin resistance independent of Leucine-mediated mTOR activationDiabetes.201564 5 1555 1563 1:CAS:528:DC%2BC2MXotVajt7s%3D 25475435 https://doi.org/10.2337/db14-1279
PubMedGoogle Scholar
DongFHuaYZhaoPRenJDuMSreejayanNChromium supplement inhibits skeletal muscle atrophy in hindlimb-suspended miceJ Nutr Biochem200920 12 992 999 1:CAS:528:DC%2BD1MXhsVajs7%2FO 19071005 https://doi.org/10.1016/j.jnutbio.2008.09.006
PubMedGoogle Scholar
SahinKOnderciMTuzcuMUstundagBCikimGOzercanIHSriramojuVJuturuVKomorowskiJREffect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated ratMetabol Clin Exp200756 1233 1240 1:CAS:528:DC%2BD2sXovFehsbc%3D https://doi.org/10.1016/j.metabol.2007.04.021
PubMed Web of Science ®Google Scholar
OrhanCSahinNTuzcuZKomorowskiJRSahinKCombined oral supplementation of chromium picolinate, docosahexaenoic acid, and boron enhances neuroprotection in rats fed a high-fat dietTurk J Med Sci201747 5 1616 1625 1:CAS:528:DC%2BC1cXitFentrvP 29152944 https://doi.org/10.3906/sag-1701-54
PubMedGoogle Scholar
SahinNHayirliAOrhanCTuzcuMAkdemirFKomorowskiJRSahinKEffects of the supplemental chromium form on performance and oxidative stress in broilers exposed to heat stressPoult Sci201796 12 4317 4324 1:CAS:528:DC%2BC1cXitlOls7bE 29053811 https://doi.org/10.3382/ps/pex249
PubMedGoogle Scholar
YoonMThe emerging role of branched-chain amino acids in insulin resistance and metabolismNutrients.20168 7 405 4963881 https://doi.org/10.3390/nu8070405 1:CAS:528:DC%2BC2sXhsVKitr3N
PubMed Web of Science ®Google Scholar
JiLLMillerRHNagleFJLardyHAStratmanFWAmino acid metabolism during exercise in trained rats: the potential role of carnitine in the metabolic fate of branched-chain amino acidsMetabolism198736 748 752 1:CAS:528:DyaL2sXksFKmtbg%3D 3600287 https://doi.org/10.1016/0026-0495(87)90111-9
PubMed Web of Science ®Google Scholar
KalyaniRREganJMDiabetes and altered glucose metabolism with agingEndocrinol Metab Clin N Am201342 2 333 347 1:CAS:528:DC%2BC3sXksFakur4%3D https://doi.org/10.1016/j.ecl.2013.02.010
PubMed Web of Science ®Google Scholar
KaatsGRBlumKPullinDKeithSCWoodRA randomized, double-masked, placebo-controlled study of the effects of chromium picolinate supplementation on body composition: a replication and extension of a previous studyCurr Ther Res199859 379 388 1:CAS:528:DyaK1cXksV2qsbc%3D https://doi.org/10.1016/S0011-393X(98)85040-6
Web of Science ®Google Scholar

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The addition of an amylopectin/chromium complex to branched-chain amino acids enhances muscle protein synthesis in rat skeletal muscle

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The addition of an amylopectin/chromium complex to branched-chain amino acids enhances muscle protein synthesis in rat skeletal muscle

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