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Original Articles

Asparagine-linked Glycosylation of the Rat Leukemia Inhibitory Factor Expressed by Simian COS7 Cells

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Pages 1318-1325 | Received 24 Dec 1997, Published online: 22 May 2014

  • 1) Hilton, D. J. LIF: lots of interesting functions. TIBS, 17, 72-76 (1992).
  • 2) Gearing, D. P. The leukemia inhibitory factor and its receptor. Adv. Immunol., 53, 31-58 (1993).
  • 3) Hilton, D. J., Nicola, N. A., and Metcalf, D. Purification of a murine leukemia inhibitory factor from Krebs ascites cells. Anal. Biochem., 173, 359-367 (1988).
  • 4) Tomida, M., Yamamoto-Yamaguchi, Y., and Hozumi, M. Induction by recombinant human granulocyte colony-stimulating factor of differentiation of mouse myeloid leukemic M1 cells. FEBS Lett., 207, 271-275 (1986).
  • 5) Mereau, A., Grey, L., Piquet-Pellorce, C., and Heath, J. K. Characterization of a binding protein for leukemia inhibitory factor localized in extracellular matrix. J. Cell Biol., 122, 713-719 (1993).
  • 6) Gearing, D. P., Gough, N. M., King, J. A., Hilton, D. J., Nicola, N. A., Simpson, R. J., Nice, E. C., Kelso, A., and Metcalf, D. Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J., 6, 3995-4002 (1987).
  • 7) Gough, N. M., Gearing, D. P., King, J. A., Willson, T. A., Hilton, D. J., and Nicola, N. A. Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor. Proc. Natl. Aca. Sci. USA, 85, 2623-2627 (1988).
  • 8) Yamamori, T., Fukada, K., Aebersold, R., Korsching, S., Fann, M.-J., and Patterson, P. H. The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor. Science, 240, 1412-1416 (1989).
  • 9) Willson, T. A., Metcalf, D., and Gough, N. M. Cross-species comparison of the sequence of the leukaemia inhibitory factor gene and its protein. Eur. J. Biochem., 204, 21-30 (1992).
  • 10) Aikawa, J., Ikeda-Naiki, S., Ohgane, J., Min, K.-S., Imamura, T., Sasai, K., Shiota, K., and Ogawa, T. Molecular cloning of rat leukemia inhibitory factor receptor alpha-chain gene and its expression during pregnancy. Biochim. Biophys. Acta, 1353, 266-276 (1997).
  • 11) Wang, Y., Nesbitt, J. E., Fuentes, N. L., and Fuller, G. M. Molecular cloning and characterization of the rat liver IL-6 signal transducing molecule, gp130. Genomics, 14, 666-672 (1992).
  • 12) Robinson, R. C., Grey, L. M., Staunton, D., Vankelecom, H., Vernallis, A. B., Moreau, J.-F. Stuart, D. I., Heath, J. K., and Jones, E. Y. The crystal structure and biological function of leukemia inhibitory factor: implications for receptor binding. Cell, 77, 1101-1116 (1994).
  • 13) Hudson, K. R., Vernallis, A. B., and Heath, J. K. Characterization of the receptor binding sites of human leukemia inhibitory factor and creation of antagonists. J. Biol. Chem., 271, 11971-11978 (1996).
  • 14) Smith, A. G., Heath, J. K., Donaldson, D. D., Wong, G. G., Moreau, J., Stahl, M., and Rogers, D. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature, 336, 688-690 (1988).
  • 15) Fukada, K. Purification and partial characterization of a cholinergic neuronal differentiation factor. Proc. Natl. Acad. Sci. USA, 82, 8795-8799 (1985).
  • 16) Gearing, D. P., Nicola, N. A., Metcalf, D., Foote, S., Willson, T. A., Gough, M., and Williams, R. L. Production of leukemia inhibitory factor in Escherichia coli by a novel procedure and its use in maintaing embryonic stem cells in culture. Biotechnology, 7, 1157-1161 (1989).
  • 17) Hirosawa, M., Miura, R., Min, K.-S., Hattori, N., Shiota, K., and Ogawa, T. A cDNA encoding a new member of the rat placental lactogen family, PL-I mosaic (PL-Im). Endocrine J., 41, 387-397 (1994).
  • 18) Kozak, M. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell, 44, 283-292 (1986).
  • 19) Takebe, Y., Seiki, M., Fujisawa, J., Hay, P., Yokota, K., Arai, K., Yoshida, M., and Arai, N. SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol., 8, 466-472 (1987).
  • 20) Karthikeyan, L., Maurel, P., Rauch, U., Margolis, R. K., and Margolis, R. U. Cloning of a major heparan sulfate proteoglycan from brain and identification as the rat form of glypican. Biochem. Biophys. Res. Commun., 188, 395-401 (1992).
  • 21) Litwack, E. D., Stipp, C. S., Kumbasar, A., and Lander, A. D. Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system. J. Neurosci., 14, 3713-3724 (1994).
  • 22) Kunkel, T. A., Roberts, J. D., and Zakour, R. A. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods in Enzymol., 154, 367-382 (1987).
  • 23) Aikawa, J., Yamashita, T., Nishiyama, M., Horinouchi, S., and Beppu, T. Effects of glycosylation on the secretion and enzyme activity of Mucor rennin, an aspartic proteinase of Mucor pusillus, produced by recombinant yeast. J. Biol. Chem., 265, 13955-13959 (1990).
  • 24) Gluzman, Y. SV40-transformed simian cells support the replication of early SV40 mutants. Cell, 23, 175-182 (1981).
  • 25) Gearing, D. P., Thut, C. J., VandenBos, T., Gimpel, S. D., Delaney, P. B., King, J., Price, V., Cosman, D., and Beckmann, M. P. Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J., 10, 2839-2848 (1991).
  • 26) Moreau, J.-F., Bonneville, M., Godard, A., Gascan, H., Gruart, V., Moore, M. A., and Soulillou, J. P. Characterization of a factor produced by human T cell clones exhibiting eosinophil-activating and burst-promoting activities. J. Immunol., 11, 3844-3849 (1987).
  • 27) Le, H. V., Ramanathan, L., Labdon, J. E., Mays-Ichinco, C. A., Syto, R., Arai, N., Hoy, P., Takebe, Y., Nagabhushan, T. L., and Trotta, P. P. Isolation and characterization of multiple variants of recombinant human interleukin 4 expressed in mammalian cells. J. Biol. Chem., 263, 10817-10823 (1988).
  • 28) Ramanathan, L., Le, H. V., Labdon, J. E., Mays-Ichinco, C. A., Syto, R., Arai, N., Nagabhushan, T. L., and Trotta, P. P. Multiple forms of recombinant murine interleukin-4 expressed in COS-7 monkey kidney cells. Biochim. Biophys. Acta, 1007, 283-288 (1989).
  • 29) Moreau, J. F., Donaldson, D. D., Bennett, F., Witek, G. J., Clark, S., C. and Wong, G. G. Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells. Nature, 336, 690-692 (1988).
  • 30) Kaplan, H. A., Weply, J. K., and Lennarz, W. J. Oligosaccharyl transferase: the central enzyme in the pathway of glycoprotein assembly. Biochim. Biophys. Acta, 906, 161-173 (1987).
  • 31) Carson, D. D., Earles, B. J., and Lennarz, W. J. Enhancement of protein glycosylation in tissue slices by dolichylphosphate. J. Biol. Chem., 256, 11552-11557 (1981).
  • 32) Cullinan, E. B., Abbondanzo, S. J., Anderson, P. S., Pollard, J. W., Lessey, B. A., and Stewart, C. L. Leukemia inhibitory factor (LIF) and LIF receptor expression in human endometrium suggests a potential autocrine/paracrine function in regulating embryo implantation. Proc. Natl. Acad. Sci. USA, 93, 3115-3120 (1996).
  • 33) Bach, L. A., Hsieh, S., Brown, A. L., and Rechler, M. M. Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts. Endocrinol., 135, 2168-2176 (1994).
  • 34) Gascan, H., Godard, A., Ferenz, C., Naulet, J., Praloran, V., Peyrat, M.-A., Hewick, R., Jacques, Y., Moreau, J.-F., and Soulillou, J.-P. Characterization and NH2-terminal amino acid sequence of natural human interleukin for DA cells: leukemia inhibitory factor. Differentiation inhibitory activity secreted by a T lymphoma cell line. J. Biol. Chem., 264, 21509-21515 (1989).
  • 35) Schmelzer, C. H., Harris, R. J., Butler, D., Yedinak, C. M., Wagner, K. L., and Burton, L. E. Glycosylation pattern and disulfide assignments of recombinant human differentiation-stimulating factor. Arch. Biochem. Biophys., 302, 484-489 (1993).
  • 36) Gavel, Y. and von Heijne, G. Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering. Protein Eng., 3, 433-442 (1990).
  • 37) Ichikawa, Y. Differentiation of a cell line of myeloid leukemia. J. Cell. Physiol., 74, 223-234 (1969).
  • 38) Smith, A. G. and Hooper, M. L. Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev. Biol., 121, 1-9 (1987).
  • 39) Peters, T. and Pinto, B. M. Structure and dynamics of oligosaccharides: NMR and modeling studies. Curr. Opin. Struct. Biol., 6, 710-720 (1996).
  • 40) Yamamoto, Y., Tomida, M., Hozumi, M., Ayusawa, D., Seno T., and Tamura, G. Effect of tunicamycin on production by mouse fibroblast L929 cells of the factor-stimulating differentiation of mouse myeloid leukemic cells and the colony-stimulating factor. Cancer Res., 41, 2534-2539 (1981).

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