- 1) Kerr, J. F., Wyllie, A. H., and Currie, A. R., Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Brit. J. Cancer, 26, 239-257 (1972).
- 2) Cohen, G. M., Caspases: the executioners of apoptosis. Biochem. J., 326, 1-16 (1997).
- 3) Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., and Earnshaw, W. C., Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature, 371, 346-347 (1994).
- 4) Shiokawa, D., Maruta, H., and Tanuma, S., Inhibitors of poly(ADP-ribose) polymerase suppress nuclear fragmentation and apoptotic-body formation during apoptosis in HL-60 cells. FEBS Lett., 413, 99-103 (1997).
- . 1989.
- . 1992.
- 7) Svedmyr, N., Harthon, L., and Lundholm, L., The relationship between the plasma concentration of free nicotinic acid and some of its pharmacologic effects in man. Clin. Pharmacol. Ther., 10, 559-570 (1969).
- 8) Dulin, W. E. and Wyse, M., Reversal of streptozotocin diabetes with nicotinamide. Proc. Soc. Exp. Biol. Med., 130, 992-994 (1969).
- 9) Ogata, S., Okumura, K., and Taguchi, H., The effects of niacin on DNA repair after N-methyl-N′-nitro-N-nitrosoguanidine treatment in normal human lymphocytes. Biosci. Biotechnol. Biochem., 61, 2116-2118 (1997).
- 10) Ogata, S., Takeuchi, M., Okumura, K., and Taguchi, H., Apoptosis induced by niacin-related compounds in HL-60 cells. Biosci. Biotechnol. Biochem., 62, 2351-2356 (1998).
- 11) Hockenbery, D. M., Oltvai, Z. N., Yin, X. M., Milliman, C. L., and Korsmeyer, S. J., Bcl-2 functions in an antioxidant pathway to prevent apoptosis., Cell, 75, 241-51 (1993).
- 12) Barbieri, D., Grassilli, E., Monti, D., Salvioli, S., Franceschini, M. G., Franchini, A., and Bellesia, E., D-ribose and deoxy-D-ribose induce apoptosis in human quiescent peripheral blood mononuclear cells. Biochem. Biophys. Res. Commun., 201, 1109-1116 (1994).
- 13) Martins, L. M., Mesner, P. W., Kottke, T. J., Basi, G. S., Sinha, S., Tung, J. S., Svingen, P. A., Madden, B. J., Takahashi, A., McCormick, D. J., and Earnshaw, W. C., Kaufmann, S. H., Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis. Blood, 90, 4238-4296 (1997).
- 14) Lozzio, C. B. and Lozzio, B. B., Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood, 45, 321-324 (1975).
- 15) Amarante-Mendes, G. P., Naekyung Kim, C., Liu, L., Huang, Y., Perkins, C. L., Green, D. R., and Bhalla, K., Bcr-Abl exerts its antiapoptotic effect against diverse apoptotic stimuli through blockage of mitochondrial release of cytochrome C and activation of caspase-3. Blood, 91, 1700-1705 (1998).
- 16) Wagner, B. A., Buettner,G. R., Oberley, L. W., and Burns, C. P., Sensitivity of K562 and HL-60 cells to edelfosine, an ether lipid drug, correlates with production of reactive oxygen species. Cancer Res., 58, 2809-2816 (1998).
- 17) McGowan, A. J., Bowie, A. G., O′ Neill, L. A., and Cotter, T. G., The production of a reactive oxygen intermediate during the induction of apoptosis by cytotoxic insult. Exp. Cell Res., 238, 248-256 (1998).
- 18) Marini, M., Frabetti, F., Brunelli, M. A., and Raggi, M. A., Inhibition of poly(ADP-ribose) polymerization preserves the glutathione pool and reverses cytotoxicity in hydrogen peroxide-treated lymphocytes. Biochem. Pharmacol., 46, 2139-2144 (1993).
- 19) Evans, G. W. and Johnson, E. C., Growth stimulating effect of picolinic acid added to rat diets. Proc. Soc. Exp. Biol. Med., 165, 457-461 (1980).
- 20) Melillo, G., Cox, G. W., Radzioch, D., and Varesio, L., Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages. J. Immunol., 150, 4031-4040 (1993).
Full access
Apoptosis Induced by Niacin-Related Compounds in K562 Cells but not in Normal Human Lymphocytes
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.