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Original Articles

Synthesis of (R)- and (S)- Muscone

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Pages 1389-1392 | Received 07 Dec 2001, Accepted 04 Feb 2002, Published online: 22 May 2014

  • 1) Vijayendra, P. K., Hagiwara, H., Katsumi, T., Hoshi, T., Suzuki, T., and Ando, M., Ring closing metathesis directed synthesis of (R)-(−)-muscone from (+)-citronellal. Tetrahedron, 56, 4397-4403 (2000) and references cited therein.
  • 2) Armstrong, S. K., Ring closing diene metathesis in organic synthesis. J. Chem. Soc., Perkin Trans. 1, 371-388 (1998) and references cited therein.
  • 3) Shwab, P., France, M. B., Ziller, J. W., and Grubbs, R. H., A series of well-defined metathesis catalysts-synthesis of [RuCl2(=CHR')(PR3)2] and its reactions. Angew. Chem., Int. Ed. Engl., 34, 2039-2041 (1995).
  • 4) Tanaka, K., Ushino, H., Kawabata, Y., and Suzuki, H., Asymmetric synthesis of (R)-(−)- and (S)-(+)-muscone by enantioselective conjugate addition of chiral dimethylcuprate to (E)-cyclopentadec-2-en-1-one. J. Chem. Soc., Perkin Trans. 1, 1445-1452 (1991).

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