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Original Articles

Purification of Conjugated Linoleic Acid Isomers through a Process Including Lipase-catalyzed Selective Esterification

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Pages 1429-1433 | Received 16 Dec 2002, Accepted 24 Feb 2003, Published online: 22 May 2014

  • 1) Pariza, M. W., CLA, A new cancer inhibitor in dairy products. Bull. Int. Dairy Fed., 257, 29-30 (1991).
  • 2) Ip, C., Chin, S. F., Scimeca, J. A., and Pariza, M. W., Mammary cancer prevention by conjugated dienoic derivatives of linoleic acid. Cancer Res., 51, 6118-6124 (1991).
  • 3) Ha, Y. L., Grimm, N. K., and Pariza, M. W., Anticarcinogens from field ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis, 8, 1881-1887 (1987).
  • 4) Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., and Pariza, M. W., Effect of conjugated linoleic acid on body composition in mice. Lipids, 32, 853-858 (1997).
  • 5) Ostrowska, E., Muralitharan, M., Cross, R. F., Bauman, D. E., and Dunshea, F. R., Dietary conjugated linoleic acids increase lean tissue and decrease fat deposition in growing pigs. J. Nutri., 129, 2037-2042 (1999).
  • 6) Rahman, S. M., Wang, Y.-M., Yotsumoto, H., Cha, J.-Y., Han, S.-Y., Inoue, S., and Yanagita, T., Effect of conjugated lonoleic acid on serum leptin concentration, body-fat accumulation, and β-oxidation of fatty acid in OLETF rats. Nutrition, 17, 385-390 (2001).
  • 7) Lee, K. N., Kritchevsky, D., and Pariza, M. W., Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis, 108, 19-25 (1994).
  • 8) Nicolosi, R. J., Rogers, E. J., Kritchevsky, D., Scimeca, J. A., and Huth, P. J., Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. Artery, 22, 266-277 (1997).
  • 9) Sugano, M., Tsujita, A., Yamasaki, M., Noguchi, M., and Yamada, K., Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids, 33, 521-527 (1998).
  • 10) Ha, Y. L., Storkson, J. M., and Pariza, M. W., Inhibition of benzo(α)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res., 50, 1097-1101 (1990).
  • 11) Park, Y., Albright, K. J., Storkson, J. M., Liu, W., Cook, M. E., and Pariza, M. W., Change in body composition in mice during feeding and withdrawal of conjugated linoleic acid. Lipids, 34, 243-248 (1999).
  • 12) Park, Y., Albright, K. J., Storkson, J. M., Liu, W., and Pariza, M. W., Evidence that the trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes in mice. Lipids, 34, 235-241 (1999).
  • 13) De Deckere, E. A., Van Amelsvoort, J. M., McNeill, G. P., and Jones, P., Effect of conjugated Linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. Br. J. Nutr., 82, 309-317 (1999).
  • 14) Nagao, K., Wang, Y.-M., Inoue, N., Han, S.-Y., Buang, Y., Noda, Y., Kouda, N., Okamatsu, H., and Yanagita, T., The 10-trans, 12-cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats. Nutrition, 19, (2003) in press.
  • 15) McNeill, G. P., Rawlins, C., and Peilow, A. C., Enzymatic enrichment of conjugated Linoleic acid isomers and incorporation into triglycerides. J. Am. Oil Chem. Soc., 76, 1265-1268 (1999).
  • 16) Nagao, T., Shimada, Y., Yamauchi-Sato, Y., Yamamoto, T., Kasai, M., Tsutsumi, K., Sugihara, A., and Tominaga, Y., Fractionation and enrichment of CLA isomers by selective esterification with Candida rugosa lipase. J. Am. Oil Chem. Soc., 79, 303-308 (2002).
  • 17) Sugihara, A., Shimada, Y., and Tominaga, Y., Separation and characterization of two molecular forms of Geotrichum candidum lipase. J. Biochem., 107, 426-430 (1990).

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