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Original Articles

Effect of Medium-chain Triglycerides on the Postprandial Triglyceride Concentration in Healthy Men

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Pages 46-53 | Received 03 Jun 2002, Accepted 09 Sep 2002, Published online: 22 May 2014

  • 1) Jousilahti, P., Tuomilehto, J., Vartiainen, E., Pekkanen, J., and Puska, P., Body weight, cardiovascular risk factors, and coronary mortality: 15-year follow-up of middle-aged men and women in eastern Finland. Circulation, 93, 1372-1379 (1996).
  • 2) Seidell, J. C., Verschuren, W. M. M., van Leer, E. M., and Kromhout, D., Overweight, underweight, and mortality: A prospective study of 48,287 men and women. Arch. Intern. Med., 156, 958-963 (1996).
  • 3) Papamandjaris, A. A., MacDougall, D. E., and Jones, P. J., Medium chain fatty acid metabolism and energy expenditure: Obesity treatment implications. Life Sci., 62, 1203-1215 (1998).
  • 4) Bach, A. C., and Babayan, V. K., Medium-chain triglycerides: an update. Am. J. Clin. Nutr., 36, 950-962 (1982).
  • 5) Bach, A. C., Ingenbleek, Y., and Frey, A., The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy? J. Lipid Res., 37, 708-726 (1996).
  • 6) Seaton, T. B., Welle, S. L., Warenko, M. K., and Campbell, R. G., Thermic effect of medium-chain and long-chain triglycerides in man. Am. J. Clin. Nutr., 44, 630-634 (1986).
  • 7) Tsuji, H., Kasai, M., Takeuchi, H., Nakamura, M., Okazaki, M., and Kondo, K., Dietary medium-chain triacylglycerols suppress accumulation of body fat in a double-blind, controlled trial in healthy men and women. J. Nutr., 131, 2853-2859 (2001).
  • 8) Cohen, J. C., Noakes, T. D., and Spinnler-Benade, A. J., Serum triglyceride responses to fatty meals: effects of meal fat content. Am. J. Clin. Nutr., 47, 825-827 (1988).
  • 9) Cohn, J. S., McNamara, J. R., Cohn, S. D., Ordovas, J. M., and Schaefer, E. J., Postprandial plasma lipoprotein changes in human subjects of different ages. J. Lipid Res., 29, 469-479 (1988).
  • 10) Jeppesen, J., Chen, Y. D. I., Zhou, M. Y., Wang, T., and Reaven, G. M., Effect of variations in oral fat and carbohydrate load on postprandial lipemia. Am. J. Clin. Nutr., 62, 1201-1205 (1995).
  • 11) Dubois, C., Beaumier, G., Juhel, C., Armand, M., Portugal, H., Pauli, A. M., Borel, P., Latge, C., and Lairon, D., Effect of graded amounts (0-50 g) of dietary fat on postprandial lipemia and lipoproteins in normolipidemic adults. Am. J. Clin. Nutr., 67, 31-38 (1998).
  • 12) Redard, C. L., Davis, P. A., and Schneeman, B. O., Dietary fiber and gender: effect on postprandial lipemia. Am. J. Clin. Nutr., 52, 837-845 (1990).
  • 13) Cara, L., Dubois, C., Borel, P., Armand, M., Senft, M., Portugal, H., Pauli, A. M., Bernard, P. M., and Lairon, D., Effects of oat bran, rice bran, wheat fiber, and wheat germ on postprandial lipemia in healthy adults. Am. J. Clin. Nutr., 55, 81-88 (1992).
  • 14) Cohen, J. C., and Berger, G. M., Effects of glucose ingestion on postprandial lipemia and triglyceride clearance in humans. J. Lipid Res., 31, 597-602 (1990).
  • 15) Shige, H., Ishikawa, T., Higashi, K., Yamashita, T., Tomiyasu, K., Yoshida, H., Hosoai, H., Ito, T., Nakajima, K., Ayaori, M., Yonemura, A., Suzukawa, M., and Nakamura, H., Effects of soy protein isolate (SPI) and casein on the postprandial lipemia in normolipidemic men. J. Nutr. Sci. Vitaminol., 44, 113-127 (1998).
  • 16) Cohen, J. C., Noakes, T. D., and Spinnler-Benade, A. J., Postprandial lipemia and chylomicron clearance in athletes and in sedentary men. Am. J. Clin. Nutr., 49, 443-447 (1989).
  • 17) Tsetsonis, N. V., Hardman, A. E., and Mastana, S. S., Acute effects of exercise on postprandial lipemia: a comparative study in trained and untrained middle-aged women. Am. J. Clin. Nutr., 65, 525-533 (1997).
  • 18) De Bruin, T. W., Brouwer, C. B., Van Linde-Sibenius Trip, M., Jansen, H., and Erkelens, D. W., Different postprandial metabolism of olive oil and soy bean oil: a possible mechanism of the high-density lipoprotein conserving effect of olive oil. Am. J. Clin. Nutr., 58, 477-483 (1993).
  • 19) Salomaa, V., Rasi, V., Pekkanen, J., Jauhiainen, M., Vahtera, E., Pietonen, P., Korhonen, H., Kuulasmaa, K., and Ehnholm, C., The effects of saturated fat and n-6 polyunsaturated fat on postprandial lipemia and hemostatic activity. Atherosclerosis, 103, 1-11 (1993).
  • 20) Bergeron, N., and Havel, R. J., Influence of diets rich in saturated and omega-6 polyunsaturated fatty acids on the postprandial responses of apolipoproteins B-48, B-100, E, and lipids in triglyceride-rich lipoproteins. Arterioscler. Thromb. Vasc. Biol., 15, 2111-2121 (1995).
  • 21) Higashi, K., Ishikawa, T., Shige, H., Tomiyasu, K., Yoshida, H., Ito, T., Nakajima, K., Yonemura, A., Sawada, S., and Nakamura, H., Olive oil increases the magnitude of postprandial chylomicron remnants compared to milk fat and safflower oil. J. Am. Coll. Nutr., 16, 429-434 (1997).
  • 22) Hill, J. O., Peters, J. C., Swift, L. L., Yang, D., Sharp, T., Abumrad, N., and Greene, H. L., Changes in blood lipids during six days of overfeeding with medium or long chain triglycerides. J. Lipid Res., 31, 407-416 (1990).
  • 23) Swift, L. L., Hill, J. O., Peters, J. C., and Green, H. L., Medium-chain fatty acids: evidence for incorporation into chylomicron triglycerides in humans. Am. J. Clin. Nutr., 52, 834-836 (1990).
  • 24) Zilversmit, D. B., Atherogenesis: a postprandial phenomenon. Circulation, 60, 473-485 (1979).
  • 25) Gianturco, S. H., and Bradley, W. A., A cellular basis for the atherogenicity of triglyceride-rich lipoproteins. Atheroscler. Rev., 22, 9-14 (1991).
  • 26) Patsch, J. R., Miesenbock, G., Hopferwieser, T., Muhlberger, V., Knapp, E., Dunn, J. K., Gotto, Jr., A. M., and Patsch, W., Relation of triglyceride metabolism and coronary artery disease: studies in the postprandial state. Arterioscler. Thromb., 12, 1336-1345 (1992).
  • 27) Seidell, J. C., Monique Verschuren, W. M., van Leer, E. M., and Kromhout, D., Overweight, underweight, and mortality. A prospective study of men and women. Arch. Intern. Med., 156, 958-963 (1996).
  • 28) Higgins, M., Kannel, W., Garrison, R., Pinsky, J., and Stokes, J., Hazards of obesity—the Framingham experience. Acta Med. Scand., 723 (Suppl.), S23-S36 (1988).
  • 29) Reeder, B. A., Angel, A., Ledoux, M., Rabkin, S. W., Young, T. K., and Sweet, L. E., Obesity and its relation to cardiovascular disease risk factors in Canadian adults. Can. Med. Assoc. J., 146, 2009-2019 (1992).
  • 30) Ko, G. T. C., Chan, J. C. N., Cockram, C. S., and Woo, J., Prediction of hypertension, diabetes, dyslipidaemia or albuminuria using simple anthropometric indexes in Hong Kong Chinese. Int. J. Obes., 23, 1136-1142 (1999).
  • 31) Inoue, S., and Zimmet, P., In “The Asia-Pacific perspective: redefining obesity and its treatment”, Japan Society for the Study of Obesity, Tokyo (2000).
  • 32) Kido, T., Kurata, H., Matsumoto, A., Tobiyama, R., Musha, T., Hayashi, K., Tamai, S., Utsunomiya, K., Tajima, N., Fidge, N., Itakura, H., and Kondo, K., Lipoprotein analysis using agarose gel electrophoresis and differential staining of lipids. J. Atheroscler. Thromb., 8, 7-13 (2001).
  • 33) Matthews, J. N. S., Altman, D. G., Campbell, M. J., and Royston, P., Analysis of serial measurements in medical research. Br. Med. J., 300, 230-235 (1990).
  • 34) Thomas, T. M., Horner, K. E., Langdon, M. M., Zhang, J. Q., Krul, E. S., Sun, G. Y., and Cox, R. H., Effect of exercise and medium-chain fatty acids on postprandial lipemia. J. Appl. Physiol., 90, 1239-1246 (2001).
  • 35) Cohn, J. S., Johnson, E. J., Millar, J. S., Cohn, S. D., Milne, R. W., Marcel, Y. L., Russell, R. M., and Schaefer, E. J., Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters. J. Lipid Res., 34, 2033-2040 (1993).
  • 36) Couillard, C., Bergeron, N., Prud'homme, D., Bergeron, J., Tremblay, A., Bouchard, C., Mauriege, P., and Despres, J. P., Postprandial triglyceride response in visceral obesity in men. Diabetes, 47, 953-960 (1998).
  • 37) Mekki, N., Christofilis, M. A., Charbonnier, M., Atlan-Gepner, C., Defoort, C., Juhel, C., Borel, P., Portugal, H., Pauli, A. M., Vialettes, B., and Lairon, D., Influence of obesity and body fat distribution on postprandial lipemia and triglyceride-rich lipoproteins in adult women. J. Clin. Endocrinol. Metab., 84, 184-191 (1999).
  • 38) Diraison, F., Dusserre, E., Vidal, H., Sothier, M., and Beylot, M., Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity. Am. J. Physiol. Endocrinol. Metab., 282, E507-513 (2002).
  • 39) Binnert, C., Pachiaudi, C., Beylot, M., Hans, D., Vandermander, J., Chantre, P., Riou, J. P., and Laville, M., Influence of human obesity on the metabolic fate of dietary long- and medium-chain triacylglycerols. Am. J. Clin. Nutr., 67, 595-601 (1998).
  • 40) Carlo, C., Suzzanne, M., Suzanne, M., Philip, T., and Timothy, C. B., A cross-over study of the effect of a single oral feeding of medium chain triglyceride oil vs. canola oil on post-ingestion plasma triglyceride levels in healthy men. Altern. Med. Rev., 4, 23-28 (1999).

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