- 1) Kleinwächter, P., Schlegel, B., Groth, I., Härtl, A., and Gräfe, U., New inhibitors of 3α-hydroxysteroid dehydrogenase, 0231A and 0231B, from Streptomyces sp. HKI0231. J. Antibiotics, 54, 510-512 (2001).
- 2) Nakatsuka, S., Miyazaki, H., and Goto, T., Synthetic studies on natural products containing oxidized diketopiperazine I. Total synthesis of (±)-Neoechinulin A, an indole alkaloid containing oxidized diketopiperazine. Tetrahedron Lett., 21, 2817-2820 (1980).
- 3) Nakatsuka, S., Miyazaki, H., and Goto, T., Regiospecific cyclization of N-benzoyl-N-(methoxymethyl)-1-methyl-α,β-dehydrotryptophan methyl ester to a 5,6-dihydroazepino[5,4,3-cd]indole derivative. A new method for introducing substituents onto the 4-position of the indole nucleus. Chem. Lett., 407-410 (1981).
- 4) Nakatsuka, S., Yamada, K., and Goto, T., Introduction of a substituent onto the 4-position of an indole nucleus by intermolecular cyclization of α,β-dehydrotryptophan methyl ester with an aldehyde. Tetrahedron Lett., 27, 4557-4558 (1986).
- 5) Teranishi, K., Hayashi, S., Nakatsuka, S., and Goto, T., A facile biomimetic synthesis of Uhle's ketone by the regioselective Friedel-Crafts cyclization of indol-3-ylpropionyl chloride. Tetrahedron Lett., 35, 8173-8176 (1994).
- 6) Teranishi, K., Hayashi, S., Nakatsuka, S., and Goto, T., Facile synthesis of Uhle's ketone by the regioselective Friedel-Crafts cyclization. Synthesis, 506-508 (1995).
- 7) Nakatsuka, S., Hayashi, T., Adachi, S., Harada, Y., and Tajima, N., Regioselective cyclization of 1-trimethylacetylindole derivatives at the 4-position of indole nucleus. Heterocyclic Commun., 3, 47-50 (1997).
- 8) Tajima, N., Shinoda, Y., and Nakatsuka, S., Biomimetic intramolecular cyclization of 1-trimethylacetyl-3-(3-methanesulfonoxybutyl)indole derivative at the 4-position of indole nucleus. Heterocyclic Commun., 6, 143-146 (2000).
- 9) Hegedus, L. S., Sestrick, M. R., Michaelson, E. T., and Harrington, P. J., Palladium-catalyzed reactions in the synthesis of 3- and 4-substituted indoles. 4. J. Org. Chem., 54, 4141-4146 (1989).
- 10) Ketcha, D. M., and Gribble, G. W., A convenient synthesis of 3-acylindoles via Friedel Crafts acylation of 1-(phenylsulfonyl)indole. A new route to pyridocarbazole-5,11-quinones and ellipticine. J. Org. Chem., 50, 5451-5457 (1985).
- 11) Nakatsuka, S., Teranishi, K., and Goto, T., Formation of 6-acylindoles from 1-acylindoles. Tetrahedron Lett., 35, 2699-2700 (1994).
- 12) Beak, P., and Brown, R. A., The tertiary amide as an effective director of ortho lithiation. J. Org. Chem., 47, 34-46 (1982).
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Total Synthesis of 0231B, an Inhibitor of 3α-Hydroxysteroid Dehydrogenase Produced by Streptomyces sp. HKI0231
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