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Original Articles

Transepithelial Permeability of Myricitrin and Its Degradation by Simulated Digestion in Human Intestinal Caco-2 Cell Monolayer

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Pages 1774-1776 | Received 18 Feb 2005, Accepted 30 May 2005, Published online: 22 May 2014

  • 1) Tsushida, T., Terao, J., Osawa, T., Naito, Y., Kondo, K., Oguni, I., Okuda, T., Kawauchi, S., Takasaki, S., Otomo, E., Yoshikawa, T., and Sakata, E., “Flavonoid no igaku” (in Japanese), Kodansha (1998).
  • 2) Luo, X., Basile, M. J., and Kennelly, E. J., Polyphenolic antioxidants from the fruits of Chrysophyllum cainito L. (star apple). J. Agric. Food Chem., 50, 1379–1382 (2002).
  • 3) Zhong, X., Otsuka, H., Ide, T., Hirata, E., Takushi, A., and Takeda, Y., Three flavonol glycosides from leaves of Myrsine seguinii. Phytochemistry, 46, 943–946 (1997).
  • 4) Washino, T., Sankabousizai tositeno yamamomo chushutubutsu. Gekkan Food Chemical (in Japanese), 9, 51–56 (1998).
  • 5) Yokomizo, A., and Moriwaki, M., Myricitrin degraded by simulated digestion inhibits oxidation of human low-density lipoprotein. Biosci. Biotechnol. Biochem., 69, 693–699 (2005).
  • 6) Miyazawa, T., Nakagawa, K., Kudo, M., Muraishi, K., and Someya, K., Direct intestinal absorption of red fruit anthocyanins, cyaniding-3-glucoside and cyaniding-3,5-diglucoside, into rats and humans. J. Agric. Food Chem., 47, 1083–1091 (1999).
  • 7) Nakagawa, K., Okuda, S., and Miyazawa, T., Dose-dependent incorporation of tea catechins, (−)-epigallocatechin-3-gallate and (−)-epigallocatechin, into human plasma. Biosci. Biotechnol. Biochem., 61, 1981–1985 (1997).
  • 8) Vaidyanathan, J. B., and Walle, T., Transport and metabolism of the tea flavonoid (−)-epicatechin by the human intestinal cell line Caco-2. Pharm. Res., 18, 1420–1425 (2001).
  • 9) Hidalgo, I. J., Raub, T. J., and Borchardt, R. T., Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology, 96, 736–749 (1989).
  • 10) Narai, A., Arai, S., and Shimizu, M., Rapid decrease in transepithelial electrical resistance of human intestinal Caco-2 cell monolayers by cytotoxic membrane perturbents. Toxicol. In Vitro, 11, 347–354 (1997).
  • 11) Konishi, Y., Hagiwara, K., and Shimizu, M., Transepithelial transport of fluorescein in Caco-2 cell monolayers and use of such transport in in vitro evaluation of phenolic acid availability. Biosci. Biotechnol. Biochem., 66, 2449–2457 (2002).
  • 12) Kim, M., Kometani, T., Okada, S., and Shimizu, M., Permeation of hesperidin glycosides across Caco-2 cell monolayers via paracellular pathway. Biosci. Biotechnol. Biochem., 63, 2183–2188 (1999).
  • 13) Ikeno, A., Hashimoto, K., Shimizu, M., Terao, J., Kumazawa, S., and Nakayama, T., Absorption and metabolism of quercetin in Caco-2 cells. Food Sci. Technol. Res., 5, 90–92 (1999).

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