318
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

A Comparison of the Unfolded Protein Response in Solid-State with Submerged Cultures of Aspergillus oryzae

&
Pages 2998-3001 | Received 07 Mar 2008, Accepted 24 Jul 2008, Published online: 22 May 2014

  • 1) Nevalainen, K. M., Te’o, V. S., and Bergquist, P. L., Heterologous protein expression in filamentous fungi. Trends Biotechnol., 23, 468–474 (2005).
  • 2) Oda, K., Kakizono, D., Yamada, O., Iefuji, H., Akita, O., and Iwashita, K., Proteomic analysis of extracellular proteins from Aspergillus oryzae grown under submerged and solid-state culture conditions. Appl. Environ. Microbiol., 72, 3448–3457 (2006).
  • 3) Conesa, A., Punt, P. J., van Luijk, N., and van den Hondel, C. A., The secretion pathway in filamentous fungi: a biotechnological view. Fungal. Genet. Biol., 33, 155–171 (2001).
  • 4) Ellgaard, L., and Helenius, A., ER quality control: towards an understanding at the molecular level. Curr. Opin. Cell Biol., 13, 431–437 (2001).
  • 5) Travers, K. J., Patil, C. K., Wodicka, L., Lockhart, D. J., Weissman, J. S., and Walter, P., Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell, 101, 249–258 (2000).
  • 6) Valkonen, M., Ward, M., Wang, H., Penttila, M., and Saloheimo, M., Improvement of foreign-protein production in Aspergillus niger var. awamori by constitutive induction of the unfolded-protein response. Appl. Environ. Microbiol., 69, 6979–6986 (2003).
  • 7) Saloheimo, M., Valkonen, M., and Penttila, M., Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi. Mol. Microbiol., 47, 1149–1161 (2003).
  • 8) Nakajima, K., Asakura, T., Maruyama, J., Morita, Y., Oike, H., Shimizu-Ibuka, A., Misaka, T., Sorimachi, H., Arai, S., Kitamoto, K., and Abe, K., Extracellular production of neoculin, a sweet-tasting heterodimeric protein with taste-modifying activity, by Aspergillus oryzae. Appl. Environ. Microbiol., 72, 3716–3723 (2006).
  • 9) Kobayashi, T., Abe, K., Asai, K., Gomi, K., Juvvadi, P. R., Kato, M., Kitamoto, K., Takeuchi, M., and Machida, M., Genomics of Aspergillus oryzae. Biosci. Biotechnol. Biochem., 71, 646–670 (2007).
  • 10) Kasuya, T., Nakajima, H., and Kitamoto, K., Cloning and characterization of the bipA gene encoding ER chaperone BiP from Aspergillus oryzae. J. Biosci. Bioeng., 88, 472–478 (1999).
  • 11) Jeenes, D. J., Pfaller, R., and Archer, D. B., Isolation and characterisation of a novel stress-inducible PDI-family gene from Aspergillus niger. Gene, 193, 151–156 (1997).
  • 12) Iwashita, K., Recent studies of protein secretion by filamentous fungi. J. Biosci. Bioeng., 94, 530–535 (2002).
  • 13) Akao, T., Gomi, K., Goto, K., Okazaki, N., and Akita, O., Subtractive cloning of cDNA from Aspergillus oryzae differentially regulated between solid-state culture and liquid (submerged) culture. Curr. Genet., 41, 275–281 (2002).
  • 14) Maruyama, J., Ohnuma, H., Yoshikawa, A., Kadokura, H., Nakajima, H., and Kitamoto, K., Production and product quality assessment of human hepatitis B virus pre-S2 antigen in submerged and solid-state cultures of Aspergillus oryzae. J. Biosci. Bioeng., 90, 118–120 (2000).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.