151
Views
48
CrossRef citations to date
0
Altmetric
Original Articles

High Methadone Dose Significantly Reduces Cocaine Use in Methadone Maintenance Treatment (MMT) Patients

, , &
Pages 43-50 | Published online: 23 Sep 2008

References

  • Dole , V P , Nyswander , M E and Kreek , M J . 1966 . Narcotic blockade . Arch Intern Med. , 118 : 304 – 9 .
  • National Consensus Development Panel on Effective Medical Treatment of Opiate Addiction . 1998 . Effective medical treatment of opiate addiction . JAMA , 280 : 1936 – 43 .
  • McLellan , A T , Arndt , I O , Metzger , D S , Woody , G E and O'Brien , C P . 1993 . The effects of psychosocial services in substance abuse treatment . JAMA , 269 : 1953 – 9 .
  • Ball , J C and Ross , A . 1991 . The effectiveness of Methadone Maintenance Treatment , New York : Springer-Verlag .
  • Rosenblum , A , Magura , S , Foote , J , Palij , M , Handelsman , L , Lovejoy , M and Stimmel , B . 1995 . Treatment intensity and reduction in drug use for cocaine-dependent methadone patients: A dose-response relationship . J Psychoactive Drugs , 27 : 151 – 9 .
  • Magura , S , Kang , S Y , Nwakeze , P C and Demsky , S . 1998 . Temporal patterns of heroin and cocaine use among methadone patients . Subst Use Misuse , 33 : 2441 – 67 .
  • Borg , L , Broe , D M , Ho , A and Kreek , M J . 1999 . Cocaine abuse sharply reduced in an effective methadone maintenance program . J Addict Dis. , 18 : 63 – 75 .
  • Magura , S , Rosenblum , A , Fong , C , Villano , C and Richman , B . 2002 . Treating cocaine-using methadone patients: Predictors of outcomes in a psychosocial clinical trial . Subst Use Misuse , 37 : 1927 – 55 .
  • Villano , C L , Rosenblum , A , Magura , S and Fong , C . 2002 . Improving treatment engagement and outcomes for cocaine-using methadone patients . Am J Drug Alcohol Abuse , 28 : 213 – 30 .
  • Kreek , M J . 1996 . Cocaine, dopamine and the endogenous opioid system . J Addict Dis. , 15 : 73 – 96 .
  • Kreek , M J . 1996 . Opioid receptors: Some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases . Neurochem Res. , 21 : 1469 – 88 .
  • Kreek , M J . 1997 . Opiate and cocaine addictions: Challenge for pharmacotherapies . Pharmacol Biochem Behav , 57 : 551 – 69 .
  • Unterwald , E M , Kreek , M J and Cuntapay , M . 2001 . The frequency of cocaine administration impacts cocaine-induced receptor alterations . Brain Res. , 900 : 103 – 9 .
  • Kreek , M J , LaForge , K S and Butelman , E . 2002 . Pharmacotherapy of addictions . Nat Rev Drug Discov , 1 : 710 – 26 .
  • Adelson , M O , Hayward , R , Bodner , G , Bleich , A , Gelkopf , M and Kreek , M J . 2000 . Replicationof an effective opiate addiction pharmacotherapeutic treatment model: Minimal need for modification in a different country . Journal of Maintenance in the Addictions , 1 : 5 – 13 .
  • Hawks , R L . 1986 . Analytical methodology . NIDA Res Monogr , 73 : 30 – 42 .
  • D'Aunno , T , Folz-Murphy , N and Lin , X . 1999 . Changes in methadone treatment practices: Results from a panel study, 1988–1995 . Am J Drug Alcohol Abuse , 25 : 681 – 99 .
  • Kreek , M J . 2000 . Methadone-related opioid agonist pharmacotherapy for heroin addiction. History, recent molecular and neurochemical research and future in mainstream medicine . Ann N Y Acad Sci. , 909 : 186 – 216 .
  • Bar-Hamburger , R , Rahav , G , Teichman , M and Rosenblum , I . 2001 . Psychoactive substance abuse in Israel 2001. Epidemiological Survey. Antidrug Authority
  • Unterwald , E M , Horne-King , J and Kreek , M J . 1992 . Chronic cocaine alters brain mu opioid receptors . Brain Res. , 584 : 314 – 8 .
  • Unterwald , E M , Rubenfeld , J M and Kreek , M J . 1994 . Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors . Neuroreport , 5 : 1613 – 6 .
  • Unterwald , E M . 2001 . Regulation of opioid receptors by cocaine . Ann N Y Acad Sci. , 937 : 74 – 92 .
  • Spangler , R , Unterwald , E M and Kreek , M J . 1993 . ‘Binge’ cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen . Brain Res Mol Brain Res. , 19 : 323 – 7 .
  • Zhou , Y , Spangler , R , Schlussman , S D , Yuferov , V P , Sora , I , Ho , A , Uhl , G R and Kreek , M J . 2002 . Effects of acute “binge” cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice . Synapse , 45 : 220 – 9 .
  • Zhang , Y , Butelman , E R , Schlussman , S D , Ho , A and Kreek , M J . 2004 . Effect of the endogenous kappa opioid agonist dynorphin A(1–17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice . Psychopharmacology (Berl.) , 172 : 422 – 9 .
  • Zubieta , J K , Gorelick , D A , Stauffer , R , Ravert , H T , Dannals , R F and Frost , J J . 1996 . Increased mu opioid receptor binding detected by PET in cocaine-dependent men is associated with cocaine craving . Nat Med. , 2 : 1225 – 9 .
  • Bain , G T and Kornetsky , C . 1987 . Naloxone attenuation of the effect of cocaine on rewarding brain stimulation . Life Sci. , 40 : 1119 – 25 .
  • Bilsky , E J , Montegut , M J , Delong , C L and Reid , L D . 1992 . Opioidergic modulation of cocaine conditioned place preferences . Life Sci. , 50 : PL85 – 90 .
  • Becker , A , Grecksch , G , Kraus , J , Loh , H H , Schroeder , H and Hollt , V . 2002 . Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient mice . Naunyn Schmiedebergs Arch Pharmacol , 365 : 296 – 302 .
  • Rawson , R A , Huber , A , McCann , M , Shoptaw , S , Farabee , D , Reiber , C and Ling , W . 2002 . A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependence . Arch Gen Psychiatry , 59 : 817 – 24 .
  • Bleich , A , Gelkopf , M , Schmidt , V , Hayward , R , Bodner , G and Adelson , M . 1999 . Correlates of benzodiazepine abuse in methadone maintenance treatment. A 1 year prospective study in an Israeli clinic . Addiction , 94 : 1533 – 40 .
  • Chaisson , R E , Bacchetti , P , Osmond , D , Brodie , B , Sande , M A and Moss , A R . 1989 . Cocaine use and HIV infection in intravenous drug users in San Francisco . JAMA , 261 : 561 – 5 .
  • Hartel , D M , Schoenbaum , E E , Selwyn , P A , Friedland , G H , Klein , R S and Drucker , E . 1996 . Patterns of heroin, cocaine and speedball injection among Bronx (USA) methadone maintenance patients: 1978–1988 . Addiction Research , 3 : 323 – 40 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.