Bibliography
- LEENDERS WPJ: Targetting VEGF in anti-angiogenic and anti-tumour therapy: where are we now? Int. I Exp. Pathol (1998) 79(6):339–346.
- FERRARA N: Role of vascular endothelial growth factor in the regulation of angiogenesis. Kidney Int. (1999) 56(3):794–814.
- Avastin fails in Phase III for breast cancer. Scrip September 11, 2002.
- HENNEQUIN LF, STOKES ESE, THOMAS AP et al: Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors. Med. Chem. (2002) 45(6):1300–1312.
- WEDGE SR, OGILVIE DJ, DUKES M et al.: ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res. (2002) 62(16):4645–4655.
- LEVIS M, ALLEBACH J, TSE KF et al: A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo. Blood (2002) 99(11):3885–3891.
- Pfizer/Pharmacia: the best pipeline in the business? Scrip July 18, 2002.
- DREVS J, HOFMANN I, HUGENSCHMIDT H et al.: Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res. (2000) 60(17):4819–24.
- WOOD JM, BOLD G, BUCHDUNGER E et al.: Endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. (2000) 60(8):2178–89.
- BOLD G, FREI J, FURET P et al: CGP 79787D (PTK787/ZK222584), CGP 84738 NVP-AAC789, NVP-AAD777 and related 1-anilino-(4-pyridylmethyflphthalazines as inhibitors of VEGF- and bFGF-induced angiogenesis. Drugs of the Future (2002) 27(1):43–55.
Websites
- http://www.gene.com/gene/news/press-releases/detailjsp?detail5087 National Cancer Institute (NCI) study demonstrates Genentech's investigational anti-angiogenesis treatment Avastin(Tm) delays time to disease progression in metastatic kidney cancer, May 20, 2002.