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Review

Modulators of lysophosphatidic acid signalling

, &
Pages 1619-1634 | Published online: 02 Mar 2005

Bibliography

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  • ••Molecular modeling directed LPA receptorligand design.
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  • ••Critical information for design of subtype-selective LPA receptor ligands.
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  • ••Review of molecular information forrational design of subtype-selective LPA receptor ligands.
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  • •OMPT as an LPA3-specific ligand.
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  • •Subtype-specific LPA receptor antagonists, DGPP.
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  • •SAR study of LPA towards its biological function.
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  • •Illustrates LPA analogues based on the amino acid backbones.
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  • •Synthesis of metabolically stable PA and LPA analogues including the LPP inhibitor.
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  • •Describes synthesis of biologically active metabolically stable LPA analogues.
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