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Research Article

Patent Update Central & Peripheral Nervous System: Recent advances in opioid and non-opioid analgesia (1992–1993)

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Pages 379-393 | Published online: 03 Mar 2008

References to Primarv Literaturess

  • FRANZ DN: Review of research on receptor pharmacol-ogy of pain and analgesia: part one. APS Bull. (1993) 3:10–13.
  • TRAYNOR JR, Einarr j: 8 -Opioid receptor subtypes andcross-talk with is-receptors. Trends Pharmacol. Sci. (1993) 14:84–86.
  • JIANG W, MOSBERG HI, PORRECA F: Modulation of the potency and efficacy of mu-mediated antinociception by delta agonists in the mouse. j Pharmacol. Exp. Ther. (1990) 254:683–689.
  • LIPP J: Review - Possible mechanisms of morphine analgesia. Clin. Neuropharmacol. (1991) 14:131–147.
  • RAFFA RB, MARTINEZ RP: Morphine antinociception is mediated through a LiCi-sensitive, 1P3-restorable path-way. Eur. J. Pharmacol. (1992) 215:357–358.
  • WILD KD, MCCORMICK J, BILSKY EJ, VANDERAH T, MCNUTT RW, CHANG K-J, PORRECA F: Antinociceptive actions of 5W373U86 in the mouse. J. Pharmacol. Exp. Ther. (1993), 267:858–867.
  • CHANG K-J, RIDGON GC, HOWARD JL, MCNUTT RW: Anovel, potent and selective nonpeptide delta opioid receptor agonist I3W373U86. J. Pharmacol. Exp. Ther. (1993), 267:852–887.
  • COMER SD, HOENICKE EM, SABLE Al, MCNUTT PW, CHANG K-J, DE COSTA BR, MOSBERG HI, WOODS JH: Convulsive effects of systemic administration of the delta opioid agonist BW373U86 in mice. J. Pharmacol. Exp. Ther. (1991) 267:888–895.
  • SOFUOGLU M, PORTOGHESE PS, TAKEMORI AE: Differ-ential antagonism of 8 opioid agonists by naltrindole and its benzofuran analogue (NTB) in mice: evidence for delta opioid receptor subtypes. J. Pharmacol. Exp. Ther. (1991) 257:676–680.
  • SOFUOGLU M, PORTOGHESE PS, TAKEMORI AE: Cross- tolerance studies in the spinal cord of I3-FNA-treated mice provides further evidence for delta opioid recep-tor subtypes. Life Sci/Pharmacol. Letts. (1991) 49:PL153-PL156.
  • JIANG Q, TAKEMORI AE, SULTANA M, PORTOGHESE PS, BOWEN WD, MOSBERG HI, PORRECA F: Differential antagonism of opioid delta antinociception by [D-ma2,Leus,cys6kiikephalin and naltrindole 5'-isothlocy-anate: evidence for delta receptor subtypes. J. Pharmacol. Exp. Ther. (1991) 257:1069–1075.
  • MATITA A, VANDERAH T, MOSBERG HI, PORRECA F: lack
  • EVANS CJ, KEITH DE JR, MORISSON H, MAGENDZO K, EDWARDS RH: Cloning of a delta opioid receptor by functional expression. Science (1992) 258:1952–1955.
  • KIEFFER BL, BERFORT K, GAVERIAUX-RUFF C, HIRTH CG: The 8-opiold receptor: isolation of a cDNA by expres-
  • WOLOZIN BL, PASTERNAK GW: Classification of multiple morphine and enkephalin binding sites in the central nervous system. Proc. Natl. Acad. Sci. USA (1981) 78:6181–6185.
  • LING GSF, SPIEGEL K, LOCKHART SH, PASTERNAK GW: Separation of opioid analgesia from respiratory depres-sion: evidence for different receptor mechanisms. J. Pharmacol. Exp. Ther. (1985) 232:149–155.
  • LING GSF, SPIEGEL K, NISHIMURA SL, PASTERNAK GW: Dissociation of morphine's analgesic and respiratory depressant actions. Eur. J. Pharmacol. (1983) 86:487–488.
  • PAUL D, PASTERNAK GW: Differential blockade by naloxonazine of two µ opiate actions: analgesia and Inhibition of gastrointestinal propulsion in the mouse: studies with naloxonazine. J. Pharmacol. Exp. Ther. (1988) 149:403–404.
  • HEYMAN JS, WILLIAMS CL, BURRS TF, MOSBERG HI, POR-RECA F: Dissociation of opioid antinociception and central gastrointestinal propulsion in the mouse: stud-ies with naloxonazine. j Pharmacol. Exp. Ther. (1988) 245:238–243.
  • LING GSF, MACLEOD JM, LEE S, LOCKHART SH, PASTER-NAK GW: Separation of morphine analgesia from physi-cal dependence. Science (1984) 226:462–464.
  • ROQUES BP, FOURNIE-ZALUSKI M-C, SOROCA E, LE-COMTE J-M, MALFROY B, LLORENS C, SCHWARTZ J-C: The enkephalinase inhibitor thiorphan shows antinocicep-tive activity in mice. Nature (London) (1980) 288:286–288.
  • LECOMTE J-M, COSTENTIN j, VLAICUIESCII A, CHAILLET P, MARCAIS-COLLADO H, LLORENS-CORTES C, LEBOYER M, SCHWARTZ J-C: Pharmacological properties of acetrophan, a parentally active `enckephalismse' inhibi-tor. J. Pharmacol. Exp. Ther. (1986) 237:937–944.
  • CHIPKIN RE, LATRANYI MB, McCHUGH D: SCH34826, an enkephalinase inhibitor analgesic, does not produce tolerance or dependence in rats. Adv. Biosci. (1989) 75:763–766.
  • MALDONADO R, FEGER J, FOURNIE-ZALUSKI M-C, RO- QUES BP: Differences in physical dependence induced by selective 11 and 5 opioid agonists and by endogenotes enkephalins protected by peptidase inhibitors. Br. Res. (1990) 520:247–254.
  • NOBLE F, TURCAUD 5, FOURNIE-ZALUSKI M-C, ROQUESBP: Repeated systemic administration of the mixed Inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphine. Eur.J. Pharmacol. (1992) 223:83–89.
  • NOBLE F, CORIC P, FOURNIE-ZALUSKI M-C, ROQUES BP:Lack of physical dependence in mice after repeated systemic administration of the mixed inhibitor prodrug of enkephalin- degrading enzymes, RB101. Eur.J. Phar-macol. (1992) 223:91–96.
  • RAFFA RB, FRIEDRICHS E, REIMANN W, SHANK RP, CODDEE, VAUGHT JL: Opioid and nonopioid components Independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.]. Pharmacol. Exp. Ther. (1992) 260:275–285.
  • RAFFA RB, FRIEDRICHS E, REIMANN W, SHANK RP, CODDEE, VAUGHT JL, JACOBY HI, SELVE N: Complementary and synergistic antinociceptive interaction between the enantiomers of tramadoL J. Pharmacol. Exp. Ther. (1993) 267:331–340.
  • MUSSAP CJ, GERAGHTY DP, BURGHER E: Short Review -Tachyldnin receptors: a radioligand binding perspec-tive. J. Neurochem. (1993) 60:1987–2009.
  • LOWE IIIJA, DROZDA SE, SNIDER RM, LONGO KP, ZORNSH, MORRONE J, JACKSON ER, MCLEAN S, BRYCE DK, BORDNER J, NAGAHISA A, KANAI Y, SUGA 0, TSUGHIYA M: The discovery of (2S3S)cis-2-octan-3-amine as a novel, nonpeptide substance P antagonist.]. Med. Chem. (1992) 35:2591–2600.
  • WATLING KJ: Nonpeptide antagonists herald new era intachykinin research. Trends Pharmacol. Sci (1992) 13:266–269.
  • YAMAMOTO T, YAKSH TL: Stereospecific effects of anonpeptide NICi selective antagonist, CP-96,345: antino-ciception in the absence of motor dysfunction. Life Sci. (1991) 49:1955–1963.
  • KURALSHI Y, HIROTA N, SATO Y, HANASHIMA N, TAKAGIH, SATOH M: Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal born in situ. Neurosci (1989) 30:241–250.
  • KANTNER RM, KIRBY ML, GOLDSTEIN BD: Increase in substance P in the dorsal horn during a chemogenic nociceptive stimulus. Br. Res, (1985) 338:196–199.
  • GUARD S, WATLING KJ: Interaction of the non-peptideNK2 receptor antagonist (±) CP-96,345 with L-type cal-cium channels in rat cerebral cortex. Br. J. Pharmacol. (1992) 106:37P.
  • BARNES PJ, BELVISI MG, ROGERS DF: Modulation ofneurogenic inflammation: novel approaches to inflam-matory disease. Trends Pharmacol. Sci. (1990) 11:185–189.
  • KYLE DJ, BURCH RM: A survey of bradykinin receptorsand their antagonists. Curr. Opin, Invest. Drugs (1993) 2:5–20.
  • FARMER SG, BURCH RM: Biochemical and molecular pharmacology of kinin receptors. Ann. Rev. Pharmacol. Toxicol. (1992) 32:511–536.
  • DRAY A, PERKINS M: Bradykinin and inflammatory pain.Trends Neurasci. (1993) 16:99–104.
  • STERANKA LR: Potential clinical utility of bradykininantagonists. Inernational Kinin Conference, Munich, Ger-many (1991): Abstract p. 108.
  • MORAN TH, ROBINSON PH, GOLDRICH MS, MCHUGH PR:Two brain cholecystokinin receptors: implications for behavioral actions. Br. Res. (1986) 362:175–179.
  • WILLS WD JR, COGGESHALL RE: In: Sensor y Mechanisms of the Spinal Cord(1991). Plenum Press, New York. pp. 134–136.
  • TUCHSCHERER MM, KNOX C, SEYBOLD VS: Substance P and cholecystokinin-like immunoreactive varicosities In somatosensory and autonomic regions of the rat spinal cord: a quantitative study of coexistence. J. Neuro-sci. (1987) 7:3984–3995.
  • ROTHMAN RB: A review of the role of anti-opioid pep-tides in morphine tolerance and dependence. Synapse (1992) 12:129–138.
  • BABER NS, DOURISH CT, HILL DR: Review Article - Therole of CCK, caerulein, and CCK antagonists in nocicep-don. Pain (1989) 39:307–328.
  • DOURISH CT, O'NEILL MF, COUGHLAN J, IUTCHENER SJ,HAWLEY D, IVERSEN SD: The selective CCK-B receptor antagonist 1,365,260 enhances morphine analgesia and prevents morphine tolerance lathe rat. Eur.J. Pharma-col. (1990) 176:35–44.
  • WIESENFELD-HALLIN Z, XU X-J, HUGHES J, HORWELL DC,HOKFELT T: PD134308, a selective antagonist of cholecystokinin type B receptor, enhances the analge-sic effect of morphine and synergistically interacts with intrathecal galanin to depress spinal nociceptive re-flexes. Proc. Natl. Acad. Sci. USA (1990) 87:7105–7109.
  • ABBRUZZESE JL, GHOLSON CF, DAUGHERTY K, LARSONE, DUBROW R, BERLIN R, LEVIN B: A pilot clinical trial of the cholecystokinin receptor antagonist MK-329 in pa-tients with advanced pancreatic cancer. Pancreas (1992) 7:165–171.
  • WILLIS WD JR, COGGESHALL RE: In: Sensory Mechanismsof the Spinal Cord (1991). Plenum Press, New York. p. 207.
  • MAX MB, KLSHORE-KUMAR R, SCHAFER SC, MEISTER B,GRACELY RH, SMOLLER B, DUBNER R: Efficacy of desipramine in painful diabetic neuropathy: a placebo-controlled triaL Pain (1991) 45:3–9.
  • BARBER A, HARTING J, WOLF H-P: Antinociceptive ef-fects of the 5-HT2 antagonist ritanserin in rats: evidence for an activation of descending monoarculnersk path-ways bathe spinal cord. Neurosci. Letts. (1989)99:234–238.
  • VAN PRAAG H, FRENK H: The role of glutamate in opiate descending inhibition of nociceptive spinal reflexes. Br. Res. (1990) 524:101–105.
  • FRANCE CP, WINGER GD, WOODS J11: Analgesic, anes-thetic, and respiratory effects of the competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 in rhesus monkeys. Br. Res. (1990) 526:355–358.
  • TRUJILLO KA, AKIL H: Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. Science (1991) 251:85–87.
  • KLEPSTAD P, MAURSET A, MOBERG ER, ØYE I: Evidenceof a role for NMDA receptors in pain perception. Eur.J. Pharmacol. (1990) 187:513–518.
  • HAUBRICH DR, WARD SJ, BAIZMAN E, BELL MR, BRAD-FORD J, FERRARI R, MILLER M, PERRONE M, PIERSON AK, SAELENS JK, LUTTINGER D: Pharmacology of pravadoline: a new analgesic agent J. Pbarmacol. Exp. Then (1990) 255:511–522.
  • JANSEN EM, HAYCOCK DA, WARD SJ, SEYBOLD VS: Dis-tribution of cannabinoid receptors in rat brain deter-mined with aminoalkylindoles. Br. Res. (1992) 575:93–102.
  • TORAY IND INC, W09315081-A (1993).
  • ROUSSEL-UCLAF, EP-534844-A (1993).
  • DUPONT MERCK PHARM CO, W09212128-A (1992).
  • Dr LO ZAMBELETTI SPA, W09215304-A (1992).
  • Dr LO ZAMBELETTI SPA, W09215592-A (1992).
  • Dr LO ZAMBELETTI SPA, W09217467-A (1992).
  • Dr LO ZAMBELETTI SPA, W09220657-A (1992).
  • GD SEARLE & CO, US5225417-A (1993).
  • GD SEARLE & CO, US5223507-A (1993).
  • Dr LO ZAMBELETTI SPA, W09301186-A (1993).
  • ALKALOIDA CHEM CO, W09213534-A (1993).
  • GLAXO INC, US5130321-A (1992).
  • WELCOME FOUNDATION LTD, '0709315062 (1993).
  • WARNER-LAMBERT CO, EP552386-A (1993).
  • H LUNDEBECK AS, W09222530-A (1992). 116, NISSHIN FLOUR MILLING CO LTD, GB22511435-AS
  • SCHERING CORP, W09211235-A (1992).
  • CIBA-GIEGY CORP, US5217996-A (1993).
  • MERREL DOW PHARM INC, EP-481522-A (1992).
  • ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI, EP- 47553-A (1992).
  • McNEILAB INC, EP-532348-A (1993).
  • McNEILAB INC, EP-546676-A (1993).
  • McNEILAB INC, EP-534628-A (1993).
  • McNEILAB INC, W09304675-A (1993).
  • PFIZER INF, W09300331-A (1993).
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  • MERCK SHARP & DOHME LTD, EP-520555-A (1992).
  • MERCK SHARP & DOHME LTD, EP-536817-A (1993).
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  • RHONE-POULENC RORER SA, EP-514274-A (1992).
  • RHONE-POULENC RORER SA, EP-514275-A (1991).
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  • FUJISAWA PHARM CO LTD, US5217952-A (1993).
  • NOVA TECH LTD PARTNERSHIP, W09311789-A (1993).
  • MERCK & CO INC, EP-481671-A (1992).
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References to the patent literature

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