Advanced search
Publication Cover
Expert Opinion on Investigational Drugs Volume 4, 1995 - Issue 3
Submit an article Journal homepage
7
Views
5
CrossRef citations to date
0
Altmetric
Research Article

Section Review: The rate-limiting step in obtaining human monoclonal antibody drug pharmaceuticals:Biologicals & Immunologicals

Mark C Glassy Hygeia Pharmaceuticals, Inc., 6555 Nancy Ridge Drive, San Diego, CA, 92121, USA
&
Michael E McKnight Hygeia Pharmaceuticals, Inc., 6555 Nancy Ridge Drive, San Diego, CA, 92121, USA
Pages 225-228 | Published online: 03 Mar 2008

References

  • TEILLAUD JL, DESAYMARD C, GUISTI AM, HASELTINE B, POLLOCK RR, YELTON DE, ZACK DJ, SCHARFF MD: Mono-clonal antibodies reveal the structural basis of antibody diversity. Science (1983) 222:721–736.
  • GLASSY MC, MCKNIGHT ME: A novel drug discovery programme utilizing the human immune response. Curr. Opin. Invest. Drugs (1993) 2:853–858.
  • GLASSY MC, MCKNIGHT ME: Pharming the human lymph node. Exp. Opin. Invest. Drugs (1994) 3:1057–1060.
  • GLASSY MC, HANDLEY HE-I, HAGIWARA H, ROYSTON I: UC 729-6, a human lymphoblastoid B cell line useful for generating antibody-secreting human-human hybrido-mas. Proc. Natl, Acad. Sci. USA (1983) 80:6327–6331.
  • GLASSY MC: Immortalization of human lymphocytes from a tumor involved lymph node. Cancer Res. (1987) 47:5181–5188.
  • GLASSY MC: Production methods for generating human monoclonal antibodies. Human Antibod. Hybridomas (1993) 4:154–165.
  • GLASSY MC, CLEVELAND PH: Use of mouse and human monoclonal antibodies in enzyme immunoflltration. Meth. Enzymol. (1986) 121:525–541.
  • LARRICK J, FRY KE: Recombinant antibodies. Human Antibod. Hybridomas (1991) 2:172–189.
  • WINTER G, MILSTEIN C: Man-made antibodies. Nature (1991) 349:293–299.
  • WALDMANN TA: Monoclonal antibodies in diagnosis and therapy. Science (1991) 252:1957–1962.
  • DILLMAN RO: Human antirnouse and antiglobulin re-sponses to monoclonal antibodies. Antibod. Immuno-conjugate Radiopharmaceut. (1990) 3:1–15.
  • LUND J, WINTER G, JONES PT, POUND JD, TANAKA T, WALKER MR, ARTYMIUK P, ARATA Y, BURTON DR, JEF-FERIS R, WOOF JM: Human FcyRI and FcyRII interact with distinct but overlapping sites on human IgG. J. lmmunol (1991) 147:2657–2662.
  • KUMPEL BM, RADEMACHER TW, ROOK GAW, WILLIAMS PJ, WILSON IBH: Galactosylation of human IgG mono-clonal anti-D produced by EBV transformed B lym-phoblastoid cell lines is dependent on culture method and affects Fc receptor mediated functional activity. Human Antibod. Hybridomas (1994) 5:xxx-xxx.
  • GLASSY MC, THARAKAN JP, CHAU PC: Serum-free media In hybridoma culture and monoclonal antibody pro-duction. Biotech no!. BioEng. (1988) 32:1015–1029.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.