Ademetionine (S-adenosylmethionine) neuropharmacology: implications for drug therapies in psychiatric and neurological disorders

Bibliography

• JANICAK PG, LIPINSKI JD, COMATY JE, WATERNAUX C: S-adenosylmethionine a literature review and prelimi-nary report. Alabama J. Med. Sci. (1988) 25:306–313.
   PubMedGoogle Scholar
• FRIEDEL HA, GOA KL, BENFIELD P: S-adenosyl-L-methionine: a review of its therapeutic potentialin liver dysfunction and affective disorders in relation to its physiological role in cell metabolism. Drugs (1989) 38(3) 389–416.
   PubMed Web of Science ®Google Scholar
• BRESSA GM: S-adenosyl-L-methionine (SAMe) as antide-pressant: meta-analysis of clinical studies. Acta. Neurol. Scand. (1994) 89 (Suppl. 154):7–14.
   Google Scholar
• SPILLMANN M, FAVA M: S-adenosylmethionine in psy-chiatric disorders - historical perspective and current aspects. CNS Drugs (1996) 6:416–425.
   Web of Science ®Google Scholar
• LIEBER CS, WILLAMS R: Recent advances inthe treatment of liver diseases. Drugs (1990) 40\(Suppl. 3):1–138.
   Google Scholar
• SCHUMACHER HR, MOSKOWITZ RW, FASSBENDER HG: Osteoarthritis: the clinical picture, pathogenesis and management with studies on a new therapeutic agent, S-adenosylmethionine. Am. J. Med. (1987) 83(5A):1–110.
   Google Scholar
• CANTONI GL: The nature of the active methyl donor formed enzymatically from L-methionie and adenosine triphosphate. J. Am. Chem. Soc. (1952) 74:2942–2943.
   Google Scholar
• OKADA G, TERAOKA H, TUSKADA K: Multiple species of mammalian S-adenosylmethionine synthetase. Bio-chemistry (1981) 20:934–940.
   Google Scholar
• SULLIVAN DM, HOFFMAN JL: Fractionation and kineticproperties of rat liver and kidney methionine adeno-syltransferase isozymes. Biochemistry (1983) 22:1636–1641.
   PubMed Web of Science ®Google Scholar
• MITSUI K, TERAOKA H, TSUKADA K: Complete purifica-tion and immunochemical analysis of S-adenosyl-methionine synthetase from bovine brain. J. Biol. Chem. (1988) 263:11211–11216.
   PubMed Web of Science ®Google Scholar
• CARL GF, BENESH FC, HUDSON JL: Effect of methionine on methyl group synthesis and activation in rat brain and liver. Biol. Psychiatry (1978) 6:661–669.
   Google Scholar
• MUDD SH, CANTONI GL: Biological transmethylation methyl-group neogenesis and other 'one carbon meta-bolic reaction dependent upon tetrahydofolic acid'. In: Comprehensive Biochemistry Florkin M, Stotz EH (EL), Elsevier, Amsterdam (1964) 15:1–47.
   Google Scholar
• FINKELSTEIN JD, KYLE WE, MARTIN JJ, PICK A: Activation of cystathionine synthase by adenosylmethionine and adenosylethionine. Biochem. Biophys. Res. Commun. (1975) 66:81–87
   PubMed Web of Science ®Google Scholar
• MCKEEVER MP, MOLLOY AM, WEIR DG, SCOTT JM: Be-taine-homocyste me methyltransferase: organ distribu-tion in man, pig and rat and subcelluar distribution in the rat. Clin. Sci. (1991) 81:551–556.
   PubMed Web of Science ®Google Scholar
• WEIR DG, KEATING S, MALLOY A: Methylat ion deficiency causes vitamin-B12 associated neuropathy in the pig. Neurochem. (1988) 51:1949–1952.
   PubMed Web of Science ®Google Scholar
• SURTEES R, LEONARD J, AUSTIN S: Association of de-myelination with deficiency of cerebrospinal fluid S-adenosylmethionine in inborn errors of methyl-transferase pathway. Lancet (1991) 338:1550–1554.
   PubMed Web of Science ®Google Scholar
• BOTTIGLIERI T: Folate, vitamin B12 and neuropsychia-tric disorders. Nutt-. Rev. (1997) 54(12) (In Press).
   Google Scholar
• GIULIDORI P, CORTELLARO M, MOREO G, STRAMENTI-NOLI G: Pharmacokinetics of S-adenosyl-L-methionine in healthy volunteers. Eur. j Clin. PharmacoL (1984) 227:119–121.
   Google Scholar
• STRAMENTINOLI G: Ademethionine as a drug. Am. J. Med.(1987) 83 (Suppl. 5A):35–42.
   Google Scholar
• BOTTIGLIERI T, CHARY TKN, LAUNDY M et al: Trans-methylation and depression. Alabama J. Med Sci. (1988) 25:296–300.
   PubMedGoogle Scholar
• TERRIZZI A, FELLIN M, GIULIDORI P: Absorption andmetabolism of orally administered S-adenosyl-L-methionine (SAMe) in healthy volunteers [Abstract]. Italian J. Gastroenterol. (1996) 28\(Suppl. 2):227.
   Google Scholar
• BOTTIGLIERI T, CHARY TKN, CARNEY MWP eta].: Cere-brospinal fluid S-adenosylmethionine in depression and dementia: the effect of parenteral and oral treat-ment. J. Neurol Neurosurg. Psychiatr. (1990) 53:1096–1098.
   Google Scholar
• CASTAGNA A, LE GRAZIE C, GIULIDORI P, BOTTIGLIERI T, LAZZARIN A: Deficiency of CSF S-adenosylmethionine (SAIde) and glutathione in HIV infected patients: the effect of parenteral treatment with SAMe. Neurology (1995)45:1678–1683.
   PubMed Web of Science ®Google Scholar
• CARNEY MWP: Neuropharmacology of S-adenosyl-me thionine. Clin. Neuropharmacol (1986) 9:235–243.
   PubMed Web of Science ®Google Scholar
• BALDESSARINI RJ: Neuropharmacology of S-adenosyl-L-me thionine. Am. J. Med. (1987) 83 (Suppl. 5A):95–103.
   Google Scholar
• BOTTIGLIERI T, HYLAND K, REYNOLDS EH: The clinical potential of Ademethionine (S-adenosylmethionine) in neurological disorders. Drugs (1994) 48:1137–152.
   Google Scholar
• ALGERI S, CATTO E, CURCIO M, PONZIO F, STRAMENTI-NOLI G: Changes in rat brain noradrenaline and sero-tonin after administration of S-adenosylmethionine. In: Biochemical, and Pharmacological Roles of Adenosyl-methionine and the Central Nervous System. Zap pia V, Usdin E, Salvatore S (Ed.), New York, Pergamon Press (1979):81–87.
   Google Scholar
• OTERO-LOSADO ME, RUBIO MC: Acute effects of S-ade-nosyl-L-methionine on catecholaminergic central func-tion. Eur. I Pharmacol. (1989) 163:353–356.
   PubMed Web of Science ®Google Scholar
• OTERO-LOSADO ME, RUBIO MC: Acute changes in 5-HT metabolism after S-adenosylmethionine administra-tion. Gen. Pharmacol (1989) 20:403–406.
   PubMedGoogle Scholar
• CURCIO M, CATTO E, STRAMENTINOLI G, ALGERI S: Effect of SAIde on 5-HT metabolism in rat brain. Prog. Neurop-sychopharmacol (1978) 2:65–71.
   PubMedGoogle Scholar
• BOTTIGLIERI T, CARNEY MWP, EDEH J et al.: S-adensoyl-methionine influences monoamine metabolism [Let-ter]. Lancet (1984) 2:224.
   PubMed Web of Science ®Google Scholar
• AGNOLI A, RUGGIERI S, CERONE CG et al.: The dopamine hypothesis of depression: results of treatment with dopaminergic drugs. In: Depressive Disorders. Grattini S, Schatauer FK (Eds.), Verlag, Stuttgart (1977):447–458.
   Google Scholar
• MISHIMA K, HIGUCHI H, KAMATA M, YOSHIMOTO M, HISHIKAWA Y: Effect of acute and chronic S-adenosyl-methionine (SAM) administration on dopaminergic function in rat striatum [Abstract]. Proc. 15 JSBP (1994):714.
   Google Scholar
• BOTTIGLIERI T, HYLAND K: Effect of S-adenosylmethion-ine on dopamine metabolism in the rat striatum: an in vivo microdialysis study. Soc. Neurosci. Abstr. (1996) 2 (2):834.
   Google Scholar
• MANN S, HILL MW: Activation of striatal tyrosine hy-droxylase: the effects of pH, ATP, and cyclic AMP, 5-adenosylmethionine and S-adenosylhomocysteine. Biochem. Pharmacol. (1983) 32:3369–3374.
   PubMed Web of Science ®Google Scholar
• CZYRAK A, ROGOZ Z, SKUZA G, ZAJACZKOWSKI W MAJJ: Antidepressant activity of S-adenosylmethionine in mice and rats. J. Basic Clin. Physic)]. Pharmacol. (1992) 3:1–17.
   PubMedGoogle Scholar
• CHARLTON CG, CROWELL B: Striatal dopamine deple-tion, tremors and hypokinesia following the intracra-nial injection of S-adenosylmethionine: a possible role of hypermethylation in Parkinsonism. Mol. Chem. Neuropathol (1995) 26:269–284.
   PubMedGoogle Scholar
• COHEN B, STRAMENTINOLI G, SOSA AL, BABB SM, OL-GIATI V: Effects of the novel antidepressant 5-adenso-sylmethionine on oci- and B-adrenoreceptors in rat brain. Eur. j Pharmacol (1989) 170:201–207.
   PubMedGoogle Scholar
• CIMINO M, VANTINI G etaL: Age-related modification ofdopaminergic and beta-adrenergic receptor system: restoration to normal activity by modifying membrane fluidity with S-adenosylmethionine. Life Sci. (1984) 34:2029–39.
   PubMed Web of Science ®Google Scholar
• HIRATA F, STRITTMATTER WJ, AXELROD J: B-adrenergicreceptor agonists increase phospholipid methylation, membrane fluidity and B-adrenergic receptor-adeny-late cyclase coupling. Proc. Natl. Acad. Sci. USA (1979) 76:368–372.
   PubMed Web of Science ®Google Scholar
• MUCCIOLI G, SCORDAMAGLIA A, BERTACCO S, DI CARLO R: Effect of S-adenosyl-L-methionine on brain mus-carinic receptors. Eur. j Pharmacol. (1992) 227:293–299.
   PubMed Web of Science ®Google Scholar
• SANCHEZ DE LA CUESTA F, MARTOS F et al.: Effect of S-adenosylmethionine on brain muscarinic subtypes of young rats. First European Congress o fPharmacology. Milan, Italy (1995). Abstract 287.
   Google Scholar
• DI PERRI B, CALDERINI G, BATTISTELLA A: Phosrholipid methylation increases [H]diazepam and [ H]GABA binding in membranes from rat cerebellum. J. Neuro-chem. (1983) 41:302–308.
   PubMed Web of Science ®Google Scholar
• KOWATCH MA ROTH GS: Effect of specific membrane perturbations on alpha-adrenergic and muscarinic-cholinergic signal transduction in rat parotid cell ag-gregates. Life Sci. (1994) 55:2003–2010.
   PubMed Web of Science ®Google Scholar
• FAVA M, GIANNELLI A, RAPISARDA V, PETRALIA A, GUARALDI GP: Rapidity of onset of the antidepressant effect of parenteral S-adenosylmethionine. Psychiatry Res. (1995) 56:295–297.
   PubMed Web of Science ®Google Scholar
• BERLANGA C, ORTEGA-SOTO HA, ONTIVEROS M, SENTIES H: Efficacy of S-adenosyl-L-methionine in speeding the onset of action of imipramine. Psychiatry Res. (1992) 44:257–262.
   PubMed Web of Science ®Google Scholar
• TAYLOR KM, RANDALL PK: Depletion of 5-adenosyl-methionine in mouse brain by antidepressive drugs. J. Pharmacol. Exp. Ther. (1975) 194:303–310
   PubMed Web of Science ®Google Scholar
• DELLE CHIAIE R, BOISSARD G: Meta-analysis of two European multicenter controlled trials with Ade-metionine (SAIde) in major depression [Abstract]. 6th World Congress of Biological Psychiatry. Nice, France (June 22–27, 1997).
   Google Scholar
• MORRISON LD, SMITH DD, STEPHEN JK: Brain 5-adeno-sylmethionine levels are severely decreased in Alzhe-imer's Disease. J. Neurochem. (1996) 67:1328–1331.
   PubMed Web of Science ®Google Scholar
• NITSCH RM, BLUSZTAJIN JK, PITTAS AG et al.: Evidence for a membrane defect in Alzheime r disease brain. Proc. Natl. Acad. Sci USA (1992) 89:1671–1675.
   PubMed Web of Science ®Google Scholar
• CUENOD CA, KAPLAN DB, MICHOT F., et a/.: Phospholipid abnormalities in early Alzheimer's disease: in vivo phosphorous 31 magnetic resonance spectroscopy. Arch. Neurol (1995) 52:89–94.
   Google Scholar
• COHEN BM, SATLIN A, ZUBENKO GS: S-adenosyl-L-methionine in the treatment of Alzheimer's disease. J. Clin. Psychopharmacol (1988) 81:43–47.
   Google Scholar
• REYNOLDS EH, GODFREY P, BOTTIGLIERI T et al.: S-ade-nosylmethionine and Alzheimer's Disease [abstract]. Neurology (1989) 39\(Suppl. 0:397.
   Google Scholar
• REYNOLDS EH, CARNEY MWP, TOONE BK et al.: Trans-methylation and neuropsychiatry. In: Biochemical, Phar-macological and Clinical Aspects of Transmethi4ation. Mato J (Ed.). Cell Biology Reviews (1987) 2:93–102.
   Google Scholar
• FONTANARI D, DI PALMA C, GIORGETTI G, VIOLANTE F, VOLTOLINA M: Effects of S-adenosyl-L-methionine on cognitive and vigilance functions in the elderly. Curr. 7her. Res. (1994) 55:682–689.
   Web of Science ®Google Scholar
• PETITO CK, NAVIA BA, CHO E-S, JORDAN BD, PRICE RW: Vacuolar myelopathy pathologically resembling sub-acute combined degeneration in patients with the aquired immundeficiency syndrome. New Engl. J. Med. (1985) 312:874–879.
   PubMed Web of Science ®Google Scholar
• NAVIA BA, JORDAN BD, PRICE RW: The AIDS dementia complex: clinical features. Ann. Neurol. (1986) 19:517–524.
   PubMed Web of Science ®Google Scholar
• MCARTHUR JC: Neurologic manifestations of AIDS. Medi-cine (1987) 66:408–437.
   Google Scholar
• SURTEES R, HYLAND K, SMITH I: Central-nervous-system methyl-group metabolism in children with neurologi-cal complications of HIV infection. Lancet (1990) 335:619–621.
   PubMed Web of Science ®Google Scholar
• KEATING JN, TRIMBLE KC, MULCAHY F, SCOTT JM, WEIR DG: Evidence of brain methyltransferase inihibition and early involvement in HIV positive patients. Lancet (1991) 337:935–939.
   PubMed Web of Science ®Google Scholar
• DI ROCCO A, TAGLIATI M, DORFMAN D, MOISE J, SIMP-SON D: Methionine treatment for AIDS-associated vacu-lar myelopathy. Neurology (1996) 46 [Abstract].
   Google Scholar
• HARDWICK DF, APPLEGARTH DA, COCKCROFT DM: Pathogenesis of methionine-induced toxcity. Metabo-lism (1970) 19:381–391.
   PubMedGoogle Scholar
• MERINO GE, JETZER T, DOIZAKI WM, NAJARIAN JS: Methionine induced hepatic coma in dogs. Am. J. Surg. (1975) 130:41–46.
   PubMed Web of Science ®Google Scholar
• HOROWITZ JH, RYPINS EB, HENDERSON JM et al.: Evi-dence for impairment of transulfuration pathway in cirrhosis. Gastroenterology (1981) 81:668–675.
   PubMed Web of Science ®Google Scholar
• TROVARELLI G, DE MEDIO GE, PORCELLATI S, STRA-MENTINOLI G, PORCELLATI G: The effect of S-Adenosyl-methionine on ischemia-induced disturbances of brain phospholipid in the gerbil. Neurochem. Res. (1983) 8:1597–1609.
   PubMed Web of Science ®Google Scholar
• KATAYMA Y, SHIMAZU J, MEMEZAWA H et al: Effects ofS-adenosyl-L-methionine on experimental cerebral is-chemia. gapanesel No to Shinkei - Brain & Nerve (1985) 37:243–247.
   PubMedGoogle Scholar
• MABE H, OHARA S, NAGI H: Effects of FO-1561 on postischemic cerebral function and metabolic recovery in experimental cerebral ischemia. [Japanese] No to Shinkei - Brain & Nerve (1986) 38:1087–1090.
   PubMedGoogle Scholar
• KOZUKA M, KUBO Y, KOBAYASHI K, IWATA N: Effects ofS-adenosyl-L-methionine upon ischemia brain edema in Mongolian gerbils and spontaneously hypertensive rats. Japanese J. Pharmacol (1988) 46:225–236.
   PubMedGoogle Scholar
• SATO H, TOBITA M, OHTOMO H, IZUMIYAMA M, KOGURE K: Effects of S-adenosyl-L-methionine on the cerebral energy metabolism and microcirculation in the rats subjected to transient forebrain ischemia. gapanesel No to Shinkei - Brain & Nerve (1987) 39:1151–1156.
   PubMedGoogle Scholar
• SATO H, HARIYAMA H, MORIGUCHI K: S-adenosyl-L-methionine protects the hippocampal CA1 neurons from the ischemic neuronal death in rat Biochem. Biophys. Res. COMMUTI. (1988) 150:491–496.
   PubMed Web of Science ®Google Scholar
• YATSUGI S, YAMAMOTO T, OHNO M, UEKI S: Effect of S-adenosyl-L-methionine on impairment of working memory induced in rats by cerebral ischemia and scopolamine. Eur. j Pharmacol (1989) 166:231–239.
   PubMed Web of Science ®Google Scholar
• CARNEY MWP, CHARY TKN, BOTTIGLIERI T etal.: Switch mechanism in affective illness and oral 5-adenosyl-methionine (SAM). Br.j Psychiatry (1987) 150:724–725.
   Google Scholar
• CRICONIA AM, ARAQUISTAIN JM, DAFFINA N, NAVAJAS F, BORDINO M: Results of treatment with S-adenosyl-L-methionine in patients with major depression and internal illness. Curr. Ther. Res. (1994) 55:666–674.
   Web of Science ®Google Scholar
• BRANDES J, ARRON RJ, BOGDANOVIC P et aL: Stimulation of malignant growth in rodents by antidepressant drugs at clinically relevant doses. Cancer Res. (1992) 52:3796–3800.
   PubMed Web of Science ®Google Scholar
• BOTTIGLIERI T, HYLAND K: S-adenosylmethionine lev-els in psychiatric and neurological disorders: a review. Acta Scand. Neurol (1994) 89 (Suppl. 154):19–26.
   Google Scholar