260
Views
8
CrossRef citations to date
0
Altmetric
Reviews

The use of progesterone and other progestational agents to prevent spontaneous preterm labour and preterm birth

, BSc MB BS & , BSc MB ChB MD FRCOG
Pages 1007-1016 | Published online: 08 Apr 2009

Bibliography

  • Magowan BA, Bain M, Juszczak E, Mcinneny K. Neonatal mortality amongst Scottish preterm singleton births (1985–1994). Br J Obstet Gynaecol 1998;105:1005-10
  • Wood NS, Marlow N, Costeloe K, et al. Neurologic and developmental disability after extremely preterm birth. N Engl J Med 2000;343:378-84
  • Petrou S. The economic consequences of preterm birth during the first 10 years of life. Br J Obstet Gynaecol 2005;112(Suppl 1):10-15
  • Ringborg A, Berg J, Norman M, et al. Preterm birth in Sweden: what are the average lengths of hospital stay and the associated patient costs? Acta Paediatr 2006;95:1550-5
  • Keirse MJ. New perspectives for the effective treatment of preterm labor. Am J Obstet Gynecol 1995;173:618-28
  • Peristats. 2008 March of Dimes Foundation. Available from: www.marchofdimes.com/peristats [Last accessed 12 August 2008]
  • Nathanielsz PW. Control of length of gestation: lessons from animals. In: Critchley H, Bennett P, Thornton S, editors, Preterm Birth. London: Royal College of Obstetricians and Gynaecologists, 2004. p. 3-12
  • Smith R, Mesiano S, Nicholson R, et al. Control of length of gestation: lessons for women. In: Critchley H, Bennett P, Thornton S, editors, Preterm Birth. London: Royal College of Obstetricians and Gynaecologists, 2004. p. 13-27
  • Romero R, Espinoza J, Mazor M, Tinnakorn C. The preterm parturition syndrome. In: Critchley H, Bennett P, Thornton S, editors, Preterm Birth. London: Royal College of Obstetricians and Gynaecologists, 2004. p. 28-60
  • Thomson AJ, Telfer JF, Young A, et al. Leukocytes infiltrate the myometrium during human parturition: further evidence that labour is an inflammatory process. Hum Reprod 1999;14:229-36
  • Rauk PN, Chiao JP. Interleukin-1 stimulates human uterine prostaglandin production through induction of cyclooxygenase-2 expression. Am J Reprod Immunol 2000;43:152-9
  • Elovitz MA, Mrinalini C. Can medroxyprogesterone acetate alter toll-like receptor expression in a mouse model of intrauterine inflammation? Am J Obstet Gynecol 2005;193:1149-55
  • Peltier MR. Immunology of term and preterm labor. Reprod Biol Endocrinol 2003;1:122-33
  • Hardy DB, Janowski BA, Corey D, et al. Progesterone receptor plays a major antiinflammatory role in human myometrial cells by antagonism of nuclear factor-kappaB activation of cyclooxygenase 2 expression. Mol Endocrinol 2006;20:2724-33
  • Sfakianaki AK, Norwitz ER. Mechanisms of progesterone action in inhibiting prematurity. J Matern Fetal Neonatal Med 2006;19:763-72
  • Allen MW, Butenandt A, Corner GW, Slotta KH. Zur nomenklatur des corpus luteum-hormons. Klin Wochenschr 1935;14:1182
  • Le Vine L. Habitual abortion: a controlled clinical study of progestational therapy. West J Surg 1964;72:30-6
  • Goldstein P, Berrier J, Rosen S, et al. A meta-analysis of randomized control trials of progestational agents in pregnancy. BJOG 1989;96:265-74
  • Daya S. Efficacy of progesterone support for pregnancy in women with recurrent miscarriage. A meta-analysis of controlled trials. Br J Obstet Gynecol 1989;96:275-80
  • Keirse MJNC. Progestogen administration in pregnancy may prevent preterm delivery. Br J Obstet Gynecol 1990;97:149-54
  • Meis PJ, Klebanoff M, Thom E, et al. Prevention of recurrent preterm delivery by 17 alpha-hydroxy progesterone caproate. N Engl J Med 2003;348:2379-85
  • da Fonseca EB, Bittar RE, Carvalho MH, Zugaib M. Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double blind study. Am J Obstet Gynecol 2003;188:419-24
  • Greene MF. Progesterone and preterm delivery – déjà vu all over again. N Engl J Med 2003;348:2453-55
  • Iams JD. Supplemental progesterone to prevent preterm birth. Am J Obstet Gynecol 2003;188:303
  • Keirse MJNC. Progesterone and preterm: 70 years of “déjà vu” or “still to be seen”? Birth 2004;31B:230-35
  • American College of Obstetricians and Gynecologists. ACOG Committee Opinion. Use of progesterone to reduce preterm birth. Obstet Gynecol 2003;102:1115-16
  • Basic Science. Discussion. In: Critchley H, Bennett P, Thornton S, editors, Preterm Birth. London: Royal College of Obstetricians and Gynaecologists, 2004. p. 88-96
  • Sanchez-Ramos L, Kaunitz AM, Delke I. Progestational agents to prevent preterm birth: a meta-analysis of randomized controlled trials. Obstet Gynecol 2005;105:273-79
  • Dodd JD, Crowther CA, Cincotta R, et al. Progesterone supplementation for preventing preterm birth: a systematic review and meta-analysis. Acta Obstet Gynecol Scand 2005;84:526-33
  • Coomarasamy A, Thangaratinam S, Gee H, Khan KS. Progesterone for the prevention of preterm birth: a critical evaluation of evidence. Eur J Obstet Gynecol Reprod Biol 2006;129:111-18
  • Mackenzie R, Walker M, Armson A, Hannah ME. Progesterone for the prevention of preterm birth among women at increased risk: a systematic review and meta-analysis of randomized controlled trials. Am J Obstet Gynecol 2006;194:1234-42
  • Dodd JM, Flenady VJ, Cincotta R, Crowther CA. Progesterone for the prevention of preterm birth: a systematic review. Obstet Gynecol 2008;112:127-34
  • Johnson JWC, Austin KL, Jones GS, et al. Efficacy of 17 alpha-hydroxyprogesterone caproate in the prevention of premature labour. N Engl J Med 1975;293:675-80
  • Rouse DJ, Caritis SN, Peaceman AM, et al. A trial of 17 alpha-hydroxyprogesterone caproate to prevent prematurity in twins. N Engl J Med 2007;357:454-61
  • da Fonseca EB, Celik E, Parra M, et al. Progesterone and the risk of preterm birth among women with a short cervix. N Engl J Med 2007;357:462-9
  • O'Brien JM, Adair CD, Lewis DF, et al. Progesterone vaginal gel for the reduction of recurrent preterm birth: primary results from a randomized, double-blind, placebo controlled trial. Ultrasound Obstet Gynecol 2007;30:687-96
  • Thornton JG. Progesterone and preterm labor – still no definite answers. N Engl J Med 2007;357:499-501
  • Lim AC, Bloemenkamp KWM, Boer K, et al. Progesterone for the prevention of preterm birth in women with multiple pregnancies: the AMPHIA trial. BMC Pregnancy Childbirth 2007;7:7-12
  • 17OHP for reduction of neonatal morbidity due to PTB in twin and triplet pregnancies. Group OM, 2006. Available from: www.clinicaltrials.gov/ct/show/NCT00163020 [Last accessed 12 August 2008]
  • Prevention of preterm delivery in twin pregnancies by 17 Alpha-hydroxyprogesterone caproate. Beirut AU, 2006. Available from: www.clinicaltrials.gov/ct/show/NCT00141908 [Last accessed 12 August 2008]
  • A double blind randomised placebo controlled study of progesterone for the prevention of preterm birth in twins. North Glasgow University Hospitals Division and Glasgow University:STOPPIT. Available from: www.charttrials.abdn.ac.uk/stoppit/ [Last accessed 12 August 2008]
  • Vaginal progesterone versus placebo in multiple pregnancy. Calgary U, 2006. Available from: www.clinicaltrials.gov/ct/show/NCT00343265 [Last accessed 12 August 2008]
  • Does progesterone prevent very preterm delivery in twin pregnancies? Rigshospitalet D, 2006. Available from: www.clinicaltrials.gov/ct/show/NCT00329914 [Last accessed 12 August 2008]
  • Facchinetti F, Paganelli S, Comitini G, et al. Cervical length changes during preterm cervical ripening: effects of 17 α-hydroxyprogesterone caproate. Am J Obstet Gynecol 2007;196:453-4
  • DeFranco EA, O'Brien JM, Adair CD, et al. Vaginal progesterone is associated with a decrease in risk for early preterm birth and improved neonatal outcome in women with a short cervix: a secondary analysis from a randomized, double-blind, placebo-controlled trial. Ultrasound Obstet Gynecol 2007;30:697-705
  • Odibo AO, Stamilio DM, Macones GA, Polsky D. 17-alpha-hydroxyprogesterone caproate for the prevention of preterm delivery: a cost effectiveness analysis. Obstet Gynecol 2006;108:492-9
  • Ness A, Baxter J, Hyslop T, Berghella V. Progesterone for preventing premature birth: practice patterns of board-certified maternal-fetal medicine specialists in the United States. J Reprod Med 2006;51:411-15
  • Dodd JM, Ashwood P, Flenady V, et al. A survey of clinician and patient attitudes towards the use of progesterone for women at risk of preterm birth. Aust NZ J Obstet Gynaecol 2007;47:106-9
  • Northen AT, Norman GS, Anderson K, et al. Follow up of children exposed in utero to 17 α-hydroxyprogesterone caproate compared with placebo. Obstet Gynecol 2007;110:865-72
  • Banks BA, Cnaan A, Morgan MA, et al. Multiple courses of antenatal corticosteroids and outcome of premature neonates. North American Thyrotropin-releasing Hormone Study Group. Am J Obstet Gynecol 1999;181:709-17
  • Ehrhardt AA, Money J. Progestin induced hermaphroditism: IQ and psychosexual identity in a study of ten girls. J Sex Res 1967;3:83-100
  • Oates-whitehead RM, Haas DM, Carrier JAK. Progestogen for preventing miscarriage. Cochrane Database Syst Rev 2003;4:CD003511; doi:10.1002/14651858.CD003511
  • Raman-Wilms L, Lin-in TSENG A, WIGHARDT S, et al. Fetal genital effects of first trimester sex hormone exposure: a meta-analysis. Obstet Gynecol 1995;85:141-9
  • Norman JE, Thomson AJ, Osman I, Ledingham MA. Cervical physiology. In: Critchley H, Bennett P, Thornton S, editors, Preterm Birth. London: Royal College of Obstetricians and Gynaecologists, 2004. p. 99-114
  • Chanrachakul B, Broughton-pipkin F, Warren AY, et al. Progesterone enhances the tocolytic effect of ritodrine in isolated pregnant human myometrium. Am J Obstet Gynecol 2005;192:458-63
  • Kam KYR, Lamont RF. Developments in the pharmacotherapeutic management of spontaneous preterm labour. Expert Opin Pharmacother 2008;9:11-6
  • Mercer BM, Goldenberg RL, Moawad AH, et al. The preterm prediction study: effect of gestational age and cause of preterm birth on subsequent obstetric outcome. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Am J Obstet Gynecol 1999;181:216-21
  • Spong CY, Meis PJ, Thom EA, et al. Progesterone for prevention of recurrent preterm birth: impact of gestational age at previous delivery. Am J Obstet Gynecol 2005;193:1127-31
  • Gonzalez-Quintero VH, Istwan NB, Rhea DJ, et al. Gestational age at initiation of 17-hydroxyprogesterone caproate (17P) and recurrent preterm delivery. J Matern Fetal Neonatal Med 2007;20:249-52
  • Rebarber A, Ferrara LA, Hanley ML, et al. Increased recurrence of preterm delivery with early cessation of 17-alpha-hydroxyprogesterone caproate. Am J Obstet Gynecol 2007;196:224e1-4
  • The OPPTIMUM Study. EUDRaCT: 2007-007950-77. MREC no 08/MRE00/6. Available from: www.opptimum.org.uk/ [Last accessed 12 August 2008]
  • Shearman RP. Hormone treatment of habitual abortion. In: Behrman SJ, Kistner RW, editors, Progress in infertility. London: J&A Churchill, 1968. p. 767-77
  • Papiernik-berkhauer E. Etude en double aveugle d'un médicament prevenant la survenue premature de l'accouchement chez les femmes à risqué élevé d'accouchement prématurée. Edition Schering Serie IV 1970;3:65-8
  • Hartikainen-Sorri AL, Kauppila A, Tuimala R. Inefficacy of 17 alpha-hydroxyprogesterone caproate in the prevention of prematurity in twin pregnancy. Obstet Gynecol 1980;56:692-5
  • Hauth JC, Gilstrap LC, Brekken AL, Hauth JM. The effect of 17 alpha-hydroxyprogesterone on pregnancy outcome in an active duty military population. Am J Obstet Gynecol 1983;146:187-90
  • Yemini M, Borenstein R, Dreazen E, et al. Prevention of premature labor by 17 alpha-hydroxyprogesterone caproate. Am J Obstet Gynecol 1985;151:574-7
  • Swyer GIM, Daley D. Progesterone implantation in habitual abortion. Br Med J 1953;1:1073-7
  • Goldzieher JW. Double blind trial of a progestin in habitual abortion. JAMA 1964;188:651-4
  • Tognoni G, Ferrario L, Inzalaco M, Crosignani PG. Progestagens in threatened abortion. Lancet 1980;2:1242-3
  • Sondergard F, Ottesen B, Detelefsen MGU, et al. Traitment par la progesteronedes menaces d'accouchement premature avec taux bas de progesterone plasmatique. Contraception-Fertilité-Sexualité 1985;13:1227-31
  • Noblot G, Audra P, Dargent D, et al. The use of micronized progesterone in the treatment of menace of preterm delivery. Eur J Obstet Gynecol Reprod Biol 1991;40:203-9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.