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Expert Opinion on Pharmacotherapy Volume 17, 2016 - Issue 5
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Editorial

Will delayed release metformin provide better management of diabetes type 2?

André J. ScheenDivision of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, CHU Liège, University of Liège, Liège, Belgium;Clinical Pharmacology Unit, CHU Liège, Center for Interdisciplinary Research on Medicines (CIRM), University of Liège, Liège, BelgiumCorrespondence[email protected]
Pages 627-630 | Received 04 Jan 2016, Accepted 27 Jan 2016, Published online: 19 Feb 2016

References

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  • Buse JB, DeFronzo RA, Rosenstock J, et al. The primary glucose-lowering effect of metformin resides in the gut, not the circulation. Results from short-term pharmacokinetic and 12-week dose-ranging studies. Diabetes Care. 2016;39:198–205.
  • Scheen AJ. Personalising metformin therapy: a clinician’s perspective. Lancet Diabetes Endocrinol. 2014;2:442–444.
  • Bakris GL, Mudaliar S, Kim T, et al. Effects of new metformin formulation in stage 3 and 4 CKD: a pilot study. J Am Soc Nephrol. 2014;25:549A.

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