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Drug Evaluation

Treatment of premenstrual dysphoric disorder with luteal phase dosing of sertraline

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Pages 2065-2078 | Published online: 02 Mar 2005

Bibliography

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  • •Documented that the prevalence of clinically significant dysphoric PMS is higher than the 5-8% strict PMDD. Women with the so-called 'subthreshold PMDD' do need treatment.
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  • •Delineates the background for the diversified treatments for PMS/PMDD.
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  • •Luteal dosing with sertraline may be even more efficacious than continuous dosing.
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  • •Confirmatory pilot study.
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  • •An encouraging pilot study.
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  • •First to demonstrate that women who respond well to continuous treatment with sertraline, also similarly respond to luteal intermittent dosing.
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