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Review

Advances in the management of chronic obstructive pulmonary disease

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Pages 1063-1082 | Published online: 02 Mar 2005

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  • ••This study provides the most convincing data on the effectiveness of systemic steroids in acute COPD exacerbation.
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  • •this is a comprehensive review of existing literature on systemic corticosteroid therapy in acute exacerbation of COPD.
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  • ••A systematic review of the role of inhaled corticosteroids in COPD.
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  • JOHNELL 0, PAUWELS R, LOFDAHL CG et al.: Bone mineral density in patients with chronic obstructive pulmonary disease treated with budesonide
  • •• Turbuhaler. Ear: Respir. J. (2002) 19(6):1058–1063.
  • In chronic obstructive pulmonary disease, a combination of ipratropium and albuterol is more effective than either agent alone. An 85-day multicenter trial. COMBIVENT Inhalation Aerosol Study Group. Chest (1994) 105(5):1411–1419.
  • Routine nebulized ipratropium and albuterol together are better than either alone in COPD. The COMBI VENT Inhalation Solution Study Group. Chest (1997) 112(6):1514–1521.
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  • •Review of clinical data and molecular mechanisms of potential beneficial effects from combination therapy.
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