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Review

A review of the clinical and economic outcomes of imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia

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Pages 2775-2787 | Published online: 24 Oct 2007

Bibliography

  • PUI CH, EVANS WE: Acute lymphoblastic leukemia. N. Engl. J. Med. (1998) 339(9):605-615.
  • JEMAL A, MURRAY T, WARD E et al.: Cancer statistics, 2005. CA Cancer J. Clin. (2005) 55(1):10-30.
  • PISANI P, BRAY F, PARKIN DM: Estimates of the world-wide prevalence of cancer for 25 sites in the adult population. Int. J. Cancer (2002) 97(1):72-81.
  • NOWELL PC, HUNGERFORD DA: A minute chromosome in human chronic granulocytic leukemia. Science (1960) 132:1497.
  • ROWLEY JD: Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature (1973) 243(5405):290-293.
  • PUI CH, RELLING MV, DOWNING JR: Acute lymphoblastic leukemia. N. Engl. J. Med. (2004) 350(15):1535-1548.
  • KURZROCK R, KANTARJIAN HM, DRUKER BJ, TALPAZ M: Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann. Intern. Med. (2003) 138(10):819-830.
  • KANTARJIAN HM, TALPAZ M, DHINGRA K et al.: Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia. Blood (1991) 78(9):2411-2418.
  • PRETI HA, O'BRIEN S, GIRALT S, BERAN M, PIERCE S, KANTARJIAN HM: Philadelphia-chromosome-positive adult acute lymphocytic leukemia: characteristics, treatment results, and prognosis in 41 patients. Am. J. Med. (1994) 97(1):60-65.
  • GOTZ G, WEH HJ, WALTER TA et al.: Clinical and prognostic significance of the Philadelphia chromosome in adult patients with acute lymphoblastic leukemia. Ann. Hematol. (1992) 64(2):97-100.
  • MAURER J, JANSSEN JW, THIEL E et al.: Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction. Lancet (1991) 337(8749):1055-1058.
  • PUI CH: Acute lymphoblastic leukemia. In: Williams Hematology (6th Edition). Beutler E, Coller BS, Lichtman MA, Kipps TJ, Seligsohn U (Eds), McGraw Hill Professional, New York (2001):1141-1161.
  • BERG SL, STEUBER P, POPLACK DG: Clinical manisfestations of acute lymphoblastic leukemia. In: Hematology, Basic Principles and Practice (3rd Edition). Hoffman R, Benz EJ Jr, Shattil SJ et al. (Eds), Churchill Livingstone, New York (2000):1070-1078.
  • PUI CH, EVANS WE: Treatment of acute lymphoblastic leukemia. N. Engl. J. Med. (2006) 354(2):166-178.
  • CORNELISSEN JJ, CARSTON M, KOLLMAN C et al.: Unrelated marrow transplantation for adult patients with poor-risk acute lymphoblastic leukemia: strong graft-versus-leukemia effect and risk factors determining outcome. Blood (2001) 97(6):1572-1577.
  • HOELZER D, GOKBUGET N, OTTMANN O et al.: Acute lymphoblastic leukemia. Hematology Am. Soc. Hematol. Educ. Program (2002):162-192.
  • PAOLUCCI G, VECCHI V, FAVRE C et al.: Treatment of childhood acute lymphoblastic leukemia. Long-term results of the AIEOP-ALL 87 study. Haematologica (2001) 86(5):478-484.
  • NYVOLD C, MADSEN HO, RYDER LP et al.: Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and an excellent outcome. Blood (2002) 99(4):1253-1258.
  • RAHIALA J, RIIKONEN P, KEKALAINEN L, PERKKIO M: Cost analysis of the treatment of acute childhood lymphocytic leukaemia according to Nordic protocols. Acta Paediatr. (2000) 89(4):482-487.
  • ISHII E, EGUCHI H, MATSUZAKI A et al.: Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors. Med. Pediatr. Oncol. (2001) 37(1):10-19.
  • MATSUZAKI A, ISHII E, NAGATOSHI Y et al.: Long-term outcome of treatment with protocols AL841, AL851, and ALHR88 in children with acute lymphoblastic leukemia: results obtained by the Kyushu-Yamaguchi children's cancer study group. Int. J. Hematol. (2001) 73(3):369-377.
  • BLOOMFIELD CD, SECKER-WALKER LM, GOLDMAN AI et al.: Six-year follow-up of the clinical significance of karyotype in acute lymphoblastic leukemia. Cancer Genet. Cytogenet. (1989) 40(2):171-185.
  • WESTBROOK CA, HOOBERMAN AL, SPINO C et al.: Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a cancer and leukemia group B study (8762). Blood (1992) 80(12):2983-2990.
  • LARSON RA, DODGE RK, BURNS CP et al.: A five-drug remission induction regimen with intensive consolidation for adults with acute lymphoblastic leukemia: cancer and leukemia group B study (8811). Blood (1995) 85(8):2025-2037.
  • THOMAS X, THIEBAUT A, OLTEANU N et al.: Philadelphia chromosome positive adult acute lymphoblastic leukemia: characteristics, prognostic factors and treatment outcome. Hematol. Cell Ther. (1998) 40(3):119-128.
  • FADERL S, KANTARJIAN HM, THOMAS DA et al.: Outcome of Philadelphia chromosome-positive adult acute lymphoblastic leukemia. Leuk. Lymphoma (2000) 36(3-4):263-273.
  • KANTARJIAN HM, O'BRIEN S, SMITH TL et al.: Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J. Clin. Oncol. (2000) 18(3):547-561.
  • ANNINO L, VEGNA ML, CAMERA A et al.: Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study. Blood (2002) 99(3):863-871.
  • RIBERA JM, ORTEGA JJ, ORIOL A et al.: Prognostic value of karyotypic analysis in children and adults with high-risk acute lymphoblastic leukemia included in the PETHEMA ALL-93 trial. Haematologica (2002) 87(2):154-166.
  • TAKEUCHI J, KYO T, NAITO K et al.: Induction therapy by frequent administration of doxorubicin with four other drugs, followed by intensive consolidation and maintenance therapy for adult acute lymphoblastic leukemia: the JALSG-ALL93 study. Leukemia (2002) 16(7):1259-1266.
  • THOMAS X, OLTEANU N, CHARRIN C, LHERITIER V, MAGAUD JP, FIERE D: Acute lymphoblastic leukemia in the elderly: the Edouard Herriot hospital experience. Am. J. Hematol. (2001) 67(2):73-83.
  • ROBAK T: Acute lymphoblastic leukaemia in elderly patients: biological characteristics and therapeutic approaches. Drugs Aging (2004) 21(12):779-791.
  • CHAO NJ, BLUME KG, FORMAN SJ, SNYDER DS: Long-term follow-up of allogeneic bone marrow recipients for Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood (1995) 85(11):3353-3354.
  • SNYDER DS, NADEMANEE AP, O'DONNELL MR et al.: Long-term follow-up of 23 patients with Philadelphia chromosome-positive acute lymphoblastic leukemia treated with allogeneic bone marrow transplant in first complete remission. Leukemia (1999) 13(12):2053-2058.
  • GOLDSTONE AH, PRENTICE HG, DURRANT IJ et al.: Allogeneic transplant (related or unrelated donor) is the preferred treatment for adult Philadelphia chromostome positive (Ph+) acute lymphoblastic leukemia (ALL): results from the International ALL trial (MRC UKALLXII/ECOG E2993). Blood (2001) 98:A856.
  • DOMBRET H, GABERT J, BOIRON JM et al.: Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia – results of the prospective multicenter LALA-94 trial. Blood (2002) 100(7):2357-2366.
  • BARRETT AJ, HOROWITZ MM, ASH RC et al.: Bone marrow transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood (1992) 79(11):3067-3070.
  • THOMAS DA, FADERL S, CORTES J et al.: Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate. Blood (2004) 103(12):4396-4407.
  • THOMAS DA, FADERL S, CORTES J et al.: Update of the hyper-CVAD and imatinib mesylate regimen in Philadelphia (Ph) positive acute lymphocytic leukemia (ALL). Proceedings of the 46th Annual Meeting of the American Society of Hematology. San Diego, USA (4 – 7 December 2004):2738.
  • RIBERA JM, ORIOL A, GONZALEZ M et al.: Treatment of Philadelphia chromosome (Ph)-positive acute lymphoblastic leukemia (ALL) with concurrent chemotherapy and imatinib mesylate. Proceedings of the 46th Annual Meeting of the American Society of Hematology, San Diego, USA (4 – 7 December 2004):4483.
  • TOWATARI M, YANADA M, USUI N et al.: Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia. Blood (2004) 104(12):3507-3512.
  • YANADA M, TAKEUCHI J, SUGIURA I et al.: High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia: a Phase II study by the Japan adult leukemia study group. J. Clin. Oncol. (2006) 24(3):460-466.
  • LEE S, KIM YJ, MIN CK et al.: The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Blood (2005) 105(9):3449-3457.
  • LEE KH, LEE JH, CHOI SJ et al.: Clinical effect of imatinib added to intensive combination chemotherapy for newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Leukemia (2005) 19(9):1509-1516.
  • DE LABARTHE A, ROUSSELOT P, HUGUET-RIGAL F et al.: Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study. Blood (2007) 109(4):1408-1413.
  • DELANNOY A, LHERITIER V, THOMAS X et al.: Treatment of Philadelphia-positive acute lymphocytic leukemia (Ph+ ALL) in the elderly with imatinib mesylate (STI571) and chemotherapy. An interim analysis of the GRAALL AFR09 trial. Proceedings of the 46th Annual Meeting of the American Society of Hematology. San Diego, USA (4 – 7 December 2004):2742.
  • WASSMANN B, PFIEFER H, GOEKBUGET N et al.: Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Blood (2006) 108(5):1469-1477.
  • HOELZER D, GOKBUGET N: Recent approaches in acute lymphoblastic leukemia in adults. Crit. Rev. Oncol. Hematol. (2000) 36(1):49-58.
  • DRUKER BJ, SAWYERS CL, KANTARJIAN H et al.: Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N. Engl. J. Med. (2001) 344(14):1038-1042.
  • OTTMANN OG, DRUKER BJ, SAWYERS CL et al.: A Phase II study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias. Blood (2002) 100(6):1965-1971.
  • OTTMANN OG, WASSMANN B, GOEKBUGET N et al.: A randomized Phase II study comparing imatinib with chemotherapy as induction therapy in elderly patients with newly diagnosed Philadelphia-positive acute lymphoid leukemias (PH+ALL). Hematol. J. (2004) 5:S112.
  • VIGNETTI M, FAZI P, CIMINO G et al.: Imatinib plus steroids induces complete remission and prolonged survival in elderly Philadelphia chromosome positive acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol. Blood (2007) 109(9):3676-3678.
  • WASSMANN B, PFEIFER H, SCHEURING UJ et al.: Early prediction of response in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) treated with imatinib. Blood (2004) 103(4):1495-1498.
  • SHIMONI A, KROGER N, ZANDER AR et al.: Imatinib mesylate (STI571) in preparation for allogeneic hematopoietic stem cell transplantation and donor lymphocyte infusions in patients with Philadelphia-positive acute leukemias. Leukemia (2003) 17(2):290-297.
  • SAVANI BN, SRINIVASAN R, ESPINOZA-DELGADO I et al.: Treatment of relapsed blast-phase Philadelphia-chromosome-positive leukaemia after non-myeloablative stem-cell transplantation with donor lymphocytes and imatinib. Lancet Oncol. (2005) 6(10):809-812.
  • ARICO M, VALSECCHI MG, CAMITTA B et al.: Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. N. Engl. J. Med. (2000) 342(14):998-1006.
  • CHAMPAGNE MA, CAPDEVILLE R, KRAILO M et al.: Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a children's oncology group Phase I study. Blood (2004) 104(9):2655-2660.
  • TOKARSKI JS, NEWITT JA, CHANG CY et al.: The structure of dasatinib (BMS-354825) bound to activated ABL kinase domain elucidates its inhibitory activity against imatinib-resistant ABL mutants. Cancer Res. (2006) 66(11):5790-5797.
  • FENG W, TRAN KT, STEPHENS JM, BOTTEMAN MF: Cost effectiveness of adding imatinib to chemotherapy in adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia: an exploratory analysis. Proceedings of the 11th Congress of the European Hematology Association, Amsterdam, The Netherlands (21 – 24 June 2006):805.
  • DURAND-ZALESKI I: Fixed price contracts: the case of pediatric acute lymphoblastic leukemia. Health Policy (1992) 21(1):65-76.
  • TRAN KT, STEPHENS JM, BOTTEMAN MF, FENG W, HAY JW: Economic and quality of life burden of high-risk acute lymphoblastic leukemia. Proceedings of the 11th Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research. Philadelphia, USA (20 – 24 May 2006):#PHM2.
  • BLOOM BS, KNORR RS, EVANS AE: The epidemiology of disease expenses. The costs of caring for children with cancer. JAMA (1985) 253(16):2393-2397.
  • BARANKO PV: A cost comparison of laboratory charges in treating childhood leukemia. A children's cancer group analysis. Am. J. Pediatr. Hematol. Oncol. (1994) 16(2):102-103.
  • YALMAN N, SARPER N, DEVECIOGLU O et al.: Fludarabine, cytarabine, G-CSF and idarubicin (FLAG-IDA) for the treatment of relapsed or poor risk childhood acute leukemia. Turk. J. Pediatr. (2000) 42(3):198-204.
  • REED SD, ANSTROM KJ, LUDMER JA, GLENDENNING GA, SCHULMAN KA: Cost-effectiveness of imatinib versus interferon-α plus low-dose cytarabine for patients with newly diagnosed chronic-phase chronic myeloid leukemia. Cancer (2004) 101:2574-2583.
  • EARLE CC, CHAPMAN RH, BAKER CS et al.: Systematic overview of cost-utility assessment in oncology. J. Clin. Oncol. (2000) 18(18):3302-3317.
  • CROTT R, ALI F, BURDETTE-RADOUX S: Cost-utility of adjuvant high-dose interferon α therapy in stage III cutaneous melanoma in Quebec. Value Health (2004) 7(4):423-432.
  • MILLER AR, CANTOR SB, PEOPLES GE, PEARLSTONE DB, SKIBBER JM: Quality of life and cost effectiveness analysis of therapy for locally recurrent rectal cancer. Dis. Colon. Rectum (2000) 43(12):1695-1701.
  • WABER DP, SHAPIRO BL, CARPENTIERI SC et al.: Excellent therapeutic efficacy and minimal late neurotoxicity in children treated with 18 grays of cranial radiation therapy for high-risk acute lymphoblastic leukemia: a 7-year follow-up study of the Dana-Farber cancer institute consortium protocol 87-01. Cancer (2001) 92(1):15-22.
  • EXTERMANN M: Acute leukemia in the elderly. Clin. Geriatr. Med. (1997) 13(2):227-244.

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