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Gene therapy for pain

, MD
Pages 1855-1866 | Published online: 06 Nov 2008

Bibliography

  • Jain KK. Pain Therapeutics – drugs, markets and companies. Jain PharmaBiotech Publications, Basel, 2008. Available from: http://pharmabiotech.ch/reports/pain/Drugs_Markets_and_Companies [Last accessed 4 October 2008]
  • Jain KK. Cell therapy for pain. Expert Opin Biol Ther 2008; In press
  • Jain KK. Gene Therapy: technologies, markets and companies, Jain PharmaBiotech Publications, Basel, 2008. Available from: http://pharmabiotech.ch/reports/genetherapy [Last accessed 7 October 2008]
  • Goss JR, Goins WF, Glorioso JC. Gene therapy applications for the treatment of neuropathic pain. Expert Rev Neurother 2007;7:487-506
  • Tavares I, Lima D. From neuroanatomy to gene therapy: searching for new ways to manipulate the supraspinal endogenous pain modulatory system. J Anat 2007;211:261-8
  • Mata M, Hao S, Fink DJ. Applications of gene therapy to the treatment of chronic pain. Curr Gene Ther 2008;8:42-8
  • Kim J, Yoon YS, Lee H, Chang JW. AAV-GAD gene for rat models of neuropathic pain and Parkinson's disease. Acta Neurochir Suppl 2008;101:99-105
  • Hollis ER 2nd, Kadoya K, Hirsch M, et al. Efficient retrograde neuronal transduction utilizing self-complementary AAV1. Mol Ther 2008;16:296-301
  • Pezet S, Krzyzanowska A, Wong LF, et al. Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF. Mol Ther 2006;13:1101-9
  • Hubbard RD, Martínez JJ, Burdick JA, Winkelstein BA. Controlled release of GDNF reduces nerve root-mediated behavioral hypersensitivity. J Orthop Res 2008; published online Jul 16 2008, doi:10.1002/jor.20710
  • Hao S, Mata M, Wolfe D, et al. HSV-mediated gene transfer of the glial cell-derived neurotrophic factor provides an antiallodynic effect on neuropathic pain. Mol Ther 2003;8:367-75
  • Zhang G, Mohammad H, Peper BD, et al. Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice. Anesthesiol 2008;108:305-13
  • Morrey ME, Anderson PA, Chambers G, Paul R. Optimizing nonviral-mediated transfection of human intervertebral disc chondrocytes. Spine J 2008;8:796-803
  • Meunier A, Latrémolière A, Mauborgne A, et al. Attenuation of pain-related behavior in a rat model of trigeminal neuropathic pain by viral-driven enkephalin overproduction in trigeminal ganglion neurons. Mol Ther 2005;11:608-16
  • Storek B, Reinhardt M, Wang C, et al. Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain. Proc Natl Acad Sci USA 2008;105:1055-60
  • Chen KH, Wu CH, Tseng CC, et al. Intrathecal coelectrotransfer of a tetracycline-inducible, three-plasmid-based system to achieve tightly regulated antinociceptive gene therapy for mononeuropathic rats. J Gene Med 2008;10:208-16
  • Glorioso JC, Mata M, Fink DJ. Gene therapy for chronic pain. Curr Opin Mol Ther 2003;5:483-8
  • Yeomans DC, Lu Y, Laurito CE, et al. Recombinant herpes vector-mediated analgesia in a primate model of hyperalgesia. Mol Ther 2006;13:589-97
  • Eaton MJ, Blits B, Ruitenberg MJ, et al. Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord. Gene Ther 2002;9:1387-95
  • Xu Y, Gu Y, Wu P, et al. Adeno-associated viral transfer of opioid receptor gene to primary sensory neurons: a strategy to increase opioid antinociception. PNAS 2003;100:6204-9
  • Chen SL, Ma HI, Han JM, et al. dsAAV type 2-mediated gene transfer of MORS196A-EGFP into spinal cord as a pain management paradigm. PNAS 2007;104:20096-101
  • Wolfe D, Hao S, Hu J, et al. Engineering an endomorphin-2 gene for use in neuropathic pain therapy. Pain 2007;133:29-38
  • Federici T, Liu JK, Teng Q, et al. A means for targeting therapeutics to peripheral nervous system neurons with axonal damage. Neurosurgery 2007;60:911-18
  • Hao S, Mata M, Wolfe D, et al. Gene transfer of glutamic acid decarboxylase reduces neuropathic pain. Ann Neurol 2005;57:914-18
  • Pohl M, Meunier A, Hamon M, Braz J. Gene therapy of chronic pain. Curr Gene Ther 2003;3:223-38
  • Jasmin L, Tien D, Janni G, Ohara PT. Is noradrenaline a significant factor in the analgesic effect of antidepressants? Pain 2003;106:3-8
  • Zou WY, Yang Y, Guo QL. Periaqueductal gray administration of HSV-I amplicon vector-mediated HPPE gene therapy of nocicepion in rats with formalin-induced pain. Zhong Nan Da Xue Xue Bao Yi Xue Ban 2008;33:481-7
  • Meunier A, Latrémolière A, Dominguez E, et al. Lentiviral-mediated targeted NF-kB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat. Mol Ther 2007;15:687-97
  • Mata M, Hao S, Fink DJ. Gene therapy directed at the neuroimmune component of chronic pain with particular attention to the role of TNF α. Neurosci Lett 2008;437:209-13
  • Ledeboer A, Jekich BM, Sloane EM, et al. Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun 2007;21:686-98
  • Milligan ED, Soderquist RG, Malone SM, et al. Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol 2006;2:293-308
  • North RA. The P2X3 subunit: a molecular target in pain therapeutics. Curr Opin Investig Drugs 2003;4:833-40
  • Ma W, Hatzis C, Eisenach JC. Intrathecal injection of cAMP response element binding protein (CREB) antisense oligonucleotide attenuates tactile allodynia caused by partial sciatic nerve ligation. Brain Res 2003;988:97-104
  • Liou JT, Liu FC, Hsin ST, et al. Inhibition of the cyclic adenosine monophosphate pathway attenuates neuropathic pain and reduces phosphorylation of cyclic adenosine monophosphate response element-binding in the spinal cord after partial sciatic nerve ligation in rats. Anesth Analg 2007;105:1830-7
  • Kort ME, Drizin I, Gregg RJ, et al. Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain. J Med Chem 2008;51:407-16
  • Jain KK. RNAi: technologies, markets and companies, Jain PharmaBiotech Publications, Basel, 2008. Available from: http://pharmabiotech.ch/reports/rnai [Last accessed 7 October 2008]
  • Dorn G, Patel S, Wotherspoon G, et al. siRNA relieves chronic neuropathic pain. Nucleic Acids Res 2004;32:e49. Published online 16 March 2004, doi:10.1093/nar/gnh044
  • Mikami M, Yang J. Short hairpin RNA-mediated selective knockdown of NaV1.8 tetrodotoxin-resistant voltage-gated sodium channel in dorsal root ganglion neurons. Anesthesiol 2005;103:828-36
  • Anesti AM, Peeters PJ, Royaux I, Coffin RS. Efficient delivery of RNA interference to peripheral neurons in vivo using herpes simplex virus. Nucleic Acids Res 2008;36:e86 doi:10.1093/nar/gkn371
  • Zhang G, Mohammad H, Peper BD, et al. Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice. Anesthesiol 2008;108:305-13
  • Kyrkanides S, Fiorentino PM, Miller JN, et al. Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1bXAT mouse model of arthritis by intraarticular induction of m-opioid receptor into the temporomandibular joint. Arthritis Rheum 2007;56:2038-48
  • Gould D, Yousaf N, Fatah R, et al. Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis. Arthritis Res Ther 2007;9:R7
  • Evans CH, Robbins PD, Ghivizzani SC, et al. Gene transfer to human joints: Progress toward a gene therapy of arthritis. Proc Natl Acad Sci USA 2005;102:8698-703
  • Kizawa H, Kou I, Iida A, et al. An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nature Genetics 2005;37:138-44
  • Tow BP, Hsu WK, Wang JC. Disc regeneration: a glimpse of the future. Clin Neurosurg 2007;54:122-8
  • Zhang Y, Phillips FM, Thonar EJ, et al. Cell therapy using articular chondrocytes overexpressing BMP-7 or BMP-10 in a rabbit disc organ culture model. Spine 2008;33:831-8
  • Le Maitre CL, Freemont AJ, Hoyland JA. A preliminary in vitro study into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. Int J Exp Pathol 2006;87:17-28
  • Wallach CJ, Kim JS, Sobajima S, et al. Safety assessment of intradiscal gene transfer: a pilot study. Spine J 2006;6:107-12
  • Moon SH, Nishida K, Gilbertson LG, et al. Biologic response of human intervertebral disc cells to gene therapy cocktail. Spine 2008;33:1850-5
  • Jain KK. Current challenges and future prospects in management of neuropathic pain. Expert Rev of Neurother 2008;8:1735-48
  • Dray A. Neuropathic pain: emerging treatments. Br J Anaesth 2008;101:48-58
  • Siniscalco D, Rossi F, Maione S. Molecular approaches for neuropathic pain treatment. Curr Med Chem 2007;14:1783-7
  • Liu W, Liu Z, Liu L, et al. A novel human foamy virus mediated gene transfer of GAD67 reduces neuropathic pain following spinal cord injury. Neurosci Lett 2008;432:13-18
  • Hao S, Mata M, Glorioso JC, Fink DJ. Gene transfer to interfere with TNFa signaling in neuropathic pain. Gene Ther 2007;14:1010-16

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