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Original Research

In vitro proliferation and differentiation of human mesenchymal stem cells on hydroxyapatite versus human demineralised bone matrix with and without osteogenic protein-1

, MD MSc FRCS, , BSc MBBS, , BSc MBBS, , BSc MBchB, , MBChB BDS MSc FDSRCS FRCS, , PhD, , PhD & , PhD show all
Pages 9-19 | Published online: 08 Dec 2008

Bibliography

  • Gie GA, Linder L, Ling RS, et al. Impacted cancellous allografts and cement for revision total hip arthroplasty. J Bone Joint Surg Br 1993;75:14-21
  • Slooff TJ, Buma P, Schreurs BW, et al. Acetabular and femoral reconstruction with impacted graft and cement. Clin Orthop Relat Res 1996;108-15
  • Oakes DA, Cabanela ME. Impaction bone grafting for revision hip arthroplasty: biology and clinical applications. J Am Acad Orthop Surg 2006;14:620-8
  • VandeVord PJ, Nasser S, Wooley PH. Immunological responses to bone soluble proteins in recipients of bone allografts. J Orthop Res 2005;23:1059-64
  • Zou S, Dodd RY, Stramer SL, Strong DM. Probability of viremia with HBV, HCV, HIV, and HTLV among tissue donors in the United States. N Engl J Med 2004;351:751-9
  • Ahlmann E, Patzakis M, Roidis N, et al. Comparison of anterior and posterior iliac crest bone grafts in terms of harvest-site morbidity and functional outcomes. J Bone Joint Surg Am 2002;84-A:716-20
  • Arts JJ, Gardeniers JW, Welten ML, et al. No negative effects of bone impaction grafting with bone and ceramic mixtures. Clin Orthop Relat Res 2005;438:239-47
  • Arts JJ, Walschot LH, Verdonschot N, et al. Biological activity of tri-calciumphosphate/hydroxyl-apatite granules mixed with impacted morsellized bone graft. A study in rabbits. J Biomed Mater Res B Appl Biomater 2007;81:476-85
  • Fujishiro T, Bauer TW, Kobayashi N, et al. Histological evaluation of an impacted bone graft substitute composed of a combination of mineralized and demineralized allograft in a sheep vertebral bone defect. J Biomed Mater Res A 2007;82:538-44
  • Grimm B, Miles AW, Turner IG. Optimizing a hydroxyapatite/tricalcium-phosphate ceramic as a bone graft extender for impaction grafting. J Mater Sci Mater Med 2001;12:929-34
  • van Haaren EH, Smit TH, Phipps K, et al. Tricalcium-phosphate and hydroxyapatite bone-graft extender for use in impaction grafting revision surgery. An in vitro study on human femora. J Bone Joint Surg Br 2005;87:267-71
  • Jensen TB, Overgaard S, Lind M, et al. Osteogenic protein-1 increases the fixation of implants grafted with morcellised bone allograft and ProOsteon bone substitute: an experimental study in dogs. J Bone Joint Surg Br 2007;89:121-6
  • McGee MA, Findlay DM, Howie DW, et al. The use of OP-1 in femoral impaction grafting in a sheep model. J Orthop Res 2004;22:1008-15
  • Soballe K, Jensen TB, Mouzin O, et al. Differential effect of a bone morphogenetic protein-7 (OP-1) on primary and revision loaded, stable implants with allograft. J Biomed Mater Res A 2004;71:569-76
  • Buma P, Arts JJ, Gardeniers JW, et al. No effect of bone morphogenetic protein-7 (OP-1) on the incorporation of impacted bone grafts in a realistic acetabular model. J Biomed Mater Res B Appl Biomater 2008;84:231-9
  • Hannink G, Aspenberg P, Schreurs BW, Buma P. High doses of OP-1 inhibit fibrous tissue ingrowth in impaction grafting. Clin Orthop Relat Res 2006;452:250-9
  • Hannink G, Schreurs BW, Buma P. No positive effects of OP-1 device on the incorporation of impacted graft materials after 8 weeks: a bone chamber study in goats. Acta Orthop 2007;78:551-8
  • Tagil M, Jeppsson C, Wang JS, Aspenberg P. No augmentation of morselized and impacted bone graft by OP-1 in a weight-bearing model. Acta Orthop Scand 2003;74:742-8
  • Karrholm J, Hourigan P, Timperley J, Razaznejad R. Mixing bone graft with OP-1 does not improve cup or stem fixation in revision surgery of the hip: 5-year follow-up of 10 acetabular and 11 femoral study cases and 40 control cases. Acta Orthop 2006;77:39-48
  • Tsiridis E, Ali Z, Bhalla A, et al. In vitro and in vivo optimization of impaction allografting by demineralization and addition of rh-OP-1. J Orthop Res 2007;25:1425-37
  • Tsiridis E, Bhalla A, Ali Z, et al. Enhancing the osteoinductive properties of hydroxyapatite by the addition of human mesenchymal stem cells, and recombinant human osteogenic protein-1 (BMP-7) in vitro. Injury 2006;37(Suppl 3):S25-32
  • Jaiswal N, Haynesworth SE, Caplan AI, Bruder SP. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J Cell Biochem 1997;64:295-312
  • Urist MR. Bone: formation by autoinduction. Science 1965;150:893-9
  • Ripamonti U. Bone induction in nonhuman primates. An experimental study on the baboon. Clin Orthop Relat Res 1991;284-94
  • Rago R, Mitchen J, Wilding G. DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water. Anal Biochem 1990;191:31-4
  • Ahmed SA, Gogal RM Jr, Walsh JE. A new rapid and simple non-radioactive assay to monitor and determine the proliferation of lymphocytes: an alternative to [3H]thymidine incorporation assay. J Immunol Methods 1994;170:211-24
  • Sabokbar A, Millett PJ, Myer B, Rushton N. A rapid, quantitative assay for measuring alkaline phosphatase activity in osteoblastic cells in vitro. Bone Miner 1994;27:57-67
  • Bae HW, Zhao L, Kanim LE, et al. Intervariability and intravariability of bone morphogenetic proteins in commercially available demineralized bone matrix products. Spine 2006;31:1299-306; discussion 307-8
  • Lee YP, Jo M, Luna M, et al. The efficacy of different commercially available demineralized bone matrix substances in an athymic rat model. J Spinal Disord Tech 2005;18:439-44
  • Bostrom MP, Yang X, Kennan M, et al. An unexpected outcome during testing of commercially available demineralized bone graft materials: how safe are the nonallograft components? Spine 2001;26:1425-8
  • Cullinane DM, Lietman SA, Inoue N, et al. The effect of recombinant human osteogenic protein-1 (bone morphogenetic protein-7) impregnation on allografts in a canine intercalary bone defect. J Orthop Res 2002;20:1240-5
  • Jensen TB, Overgaard S, Lind M, et al. Osteogenic protein 1 device increases bone formation and bone graft resorption around cementless implants. Acta Orthop Scand 2002;73:31-9
  • Lian JB, Stein GS. Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation. Crit Rev Oral Biol Med 1992;3:269-305
  • Poynton AR, Lane JM. Safety profile for the clinical use of bone morphogenetic proteins in the spine. Spine 2002;27:S40-8
  • Han B, Tang B, Nimni ME. Quantitative and sensitive in vitro assay for osteoinductive activity of demineralized bone matrix. J Orthop Res 2003;21:648-54
  • Marks T, Wingerter S, Franklin L, et al. Histological and radiographic comparison of allograft substitutes using a continuous delivery model in segmental defects. Biomed Sci Instrum 2007;43:194-9
  • Coathup M, Smith N, Kingsley C, et al. Impaction grafting with a bone-graft substitute in a sheep model of revision hip replacement. J Bone Joint Surg Br 2008;90:246-53
  • Munro NA, Downing MR, Meakin JR, et al. A hydroxyapatite graft substitute reduces subsidence in a femoral impaction grafting model. Clin Orthop Relat Res 2007;455:246-52
  • Takigami H, Kumagai K, Latson L, et al. Bone formation following OP-1 implantation is improved by addition of autogenous bone marrow cells in a canine femur defect model. J Orthop Res 2007;25:1333-42
  • Santoni BG, Pluhar GE, Motta T, Wheeler DL. Hollow calcium phosphate microcarriers for bone regeneration: in vitro osteoproduction and ex vivo mechanical assessment. Biomed Mater Eng 2007;17:277-89
  • Korda M, Blunn G, Goodship A, Hua J. Use of mesenchymal stem cells to enhance bone formation around revision hip replacements. J Orthop Res 2008;26:880-5
  • Mushipe MT, Chen X, Jennings D, Li G. Cells seeded on MBG scaffold survive impaction grafting technique: Potential application of cell-seeded biomaterials for revision arthroplasty. J Orthop Res 2006;24:501-7
  • Korda M, Blunn G, Phipps K, et al. Can mesenchymal stem cells survive under normal impaction force in revision total hip replacements? Tissue Eng 2006;12:625-30

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