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Review

Vaccines for Category A bioterrorism diseases

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Pages 883-893 | Published online: 23 Feb 2005

Bibliography

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  • ••An excellent review of aspects of anthrax asit would present as a cause of biological warfare. Rewritten after the post September 11 US mail outbreak.
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  • ••The most up-to-date ACIP overview of thecurrently available US anthrax vaccine.
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  • •An example of the use of DNA (genetic or genomic) immunisation to prevent a biological warfare disease, in this case anthrax.
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  • •An example of the use of bioabsorbable microsphere technology to produce a mucosal immunogen to prevent anthrax.
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  • ••An excellent review of smallpox as it couldbe utilised as a biological warfare agent.
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  • ••The latest AC1P guidelines related to thesmallpox (vaccinia) vaccine with discussions on the potential for new immunogens and strategies for use in a bioterrorist setting.
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  • •A well done study investigating the utility of dilution of the smallpox vaccine to allow potential immunisation of a larger number of susceptibles.
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  • •The parallel study of reference 32 which looks into the humoral and cellular responses to immunisation of the diluted vaccinia vaccine.
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  • ••An excellent review on the potential use oftularaemia in the setting of biological warfare.
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  • ••One of the best reviews regarding what isunderstood about the vaccine to prevent tularaemia.
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  • ••An excellent review on plague as apotential biowarfare agent.
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  • ••The latest ACIP document on theprevention of plague, including a discussion on the inactivated whole-cell plague vaccine that was available in the US.
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  • •A well organised and thoroughly referenced review on the history of vaccines against Yersinia pestis.
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  • •An example of the kind of multiple target subunit vaccine that could be a prototype for a highly protective irnmunogen with a low side effect profile.
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  • •Another example of the use of mucosal immunisation using biodegradable microspheres containing target antigens that has great potential in the future field of vaccinology.
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  • ••An excellent review on the possibility ofbotulinum toxin being utilised as an agent of biological warfare.
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  • •This study illustrates the use of the Venezuelan encephalitis vector system as an example of a chimeric agent without replicative potential as an irnmunogen, in this case for type A botulism.
  • WU HC, YEH CT, HUANG YL et al.:Characterization of neutralizing antibodies and identification of neutralizing epitope mimics on the Clostridium botulinum neurotwdn type A. Appl. Environ. Microbial. (2001) 67:3201–3207.
  • http://www.hopkins-biodefense.org
  • Johns Hopkins Center for Biodefense website.

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