Development of an encapsulated stem cell-based therapy for diabetes

Bibliography

• International Diabetes Federation (IDF), IDF Diabetes ATLAS, Sixth edition 2014
   Google Scholar
• Pugliese A. Advances in the etiology and mechanisms of type 1 diabetes. Discov Med 2014;18(98):141-50
   PubMedGoogle Scholar
• Cabrera O, Berman DM, Kenyon NS, et al. The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci USA 2006;103(7):2334-9
   PubMed Web of Science ®Google Scholar
• van Belle TL, Coppieters KT, von Herrath MG. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 2011;91(1):79-118
   PubMed Web of Science ®Google Scholar
• Pugliese A. The multiple origins of Type 1 diabetes. Diabet Med 2013;30(2):135-46
   PubMed Web of Science ®Google Scholar
• Bogdani M, Korpos E, Simeonovic CJ, et al. Extracellular matrix components in the pathogenesis of type 1 diabetes. Curr Diab Rep 2014;14(12):552
   PubMed Web of Science ®Google Scholar
• Tanenberg RJ, Newton CA, Drake AJ. Confirmation of hypoglycemia in the “dead-in-bed” syndrome, as captured by a retrospective continuous glucose monitoring system. Endocrine practice 2010;16(2):244-8
   PubMed Web of Science ®Google Scholar
• Ly TT, Nicholas JA, Retterath A, et al. Effect of sensor-augmented insulin pump therapy and automated insulin suspension vs standard insulin pump therapy on hypoglycemia in patients with type 1 diabetes: a randomized clinical trial. Jama 2013;310(12):1240-7
   PubMed Web of Science ®Google Scholar
• Russell SJ, El-Khatib FH, Sinha M, et al. Outpatient glycemic control with a bionic pancreas in type 1 diabetes. N Engl J Med 2014;371(4):313-25
   PubMed Web of Science ®Google Scholar
• Ricordi C, Lacy PE, Finke EH, et al. Automated method for isolation of human pancreatic islets. Diabetes 1988;37(4):413-20
   PubMed Web of Science ®Google Scholar
• Piemonti L, Pileggi A. 25 Years of the Ricordi Automated Method for Islet Isolation. CellR4 2013;1(1):e128
   Google Scholar
• Tzakis AG, Ricordi C, Alejandro R, et al. Pancreatic islet transplantation after upper abdominal exenteration and liver replacement. Lancet 1990;336(8712):402-5
   PubMed Web of Science ®Google Scholar
• Gibly RF, Graham JG, Luo X, et al. Advancing islet transplantation: from engraftment to the immune response. Diabetologia 2011;54(10):2494-505
   PubMed Web of Science ®Google Scholar
• Ricordi C. Islet transplantation: a brave new world. Diabetes 2003;52(7):1595-603
   PubMed Web of Science ®Google Scholar
• Ricordi C, Strom TB. Clinical islet transplantation: advances and immunological challenges. Nat Rev Immunol 2004;4(4):259-68
   PubMed Web of Science ®Google Scholar
• Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343(4):230-8
   PubMed Web of Science ®Google Scholar
• Collaborative Islet Transplant Registry Coordinating Center - The EMMES, Coproration R, MD. Seventh Annual Report. 2010
   Google Scholar
• Bruni A, Gala-Lopez B, Pepper AR, et al. Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challenges. Diabetes Metab Syndr Obes 2014;7:211-23
   PubMedGoogle Scholar
• Basta G, Calafiore R. Immunoisolation of pancreatic islet grafts with no recipient’s immunosuppression: actual and future perspectives. Curr Diab Rep 2011;11(5):384-91
   PubMed Web of Science ®Google Scholar
• Scharp DW, Marchetti P. Encapsulated islets for diabetes therapy: history, current progress, and critical issues requiring solution. Adv Drug Deliv Rev 2014;67-68:35-73
   PubMed Web of Science ®Google Scholar
• Ryan EA, Bigam D, Shapiro AM. Current indications for pancreas or islet transplant. Diabetes Obes Metabol 2006;8(1):1-7
   PubMed Web of Science ®Google Scholar
• de Vos P, Lazarjani HA, Poncelet D, Faas MM. Polymers in cell encapsulation from an enveloped cell perspective. Adv Drug Deliv Rev 2014;67-68:15-34
   PubMed Web of Science ®Google Scholar
• Van Schilfgaarde R, De Vos P. Factors influencing the properties and performance of microcapsules for immunoprotection of pancreatic islets. J Mol Med 1999;77:199-205
   PubMed Web of Science ®Google Scholar
• Barkai U, Weir GC, Colton CK, et al. Enhanced oxygen supply improves islet viability in a new bioartificial pancreas. Cell Transplant 2013;22(8):1463-76
   PubMed Web of Science ®Google Scholar
• Ludwig B, Reichel A, Steffen A, et al. Transplantation of human islets without immunosuppression. Proc Natl Acad Sci U S A 2013;110(47):19054-8
   PubMed Web of Science ®Google Scholar
• Kumagai-Braesch M, Jacobson S, Mori H, et al. The TheraCyte device protects against islet allograft rejection in immunized hosts. Cell Transplant 2013;22(7):1137-46
   PubMed Web of Science ®Google Scholar
• Rafael E, Wernerson A, Arner P, Tibell A. In vivo studies on insulin permeability of an immunoisolation device intended for islet transplantation using the microdialysis technique. Eur Surg Res 1999;31(3):249-58
   PubMed Web of Science ®Google Scholar
• Uludag H, De Vos P, Tresco PA. Technology of mammalian cell encapsulation. Adv Drug Deliv Rev 2000;42(1-2):29-64
   PubMed Web of Science ®Google Scholar
• Brendel MH, Schulz A, Bretzel R. International Islet Transplant Registry report. University of Giessen; Giessen, Germany: 1999
   Google Scholar
• Spector M, Cease C, Tong-Li X. The local tissue response to biomaterials. Crit Rev Biocomp 1989;5:269-95
   Web of Science ®Google Scholar
• Chang TM. Semipermeable Microcapsules. Science (New York, NY) 1964;146(3643):524-5
   Web of Science ®Google Scholar
• Winn SR, Tresco PA, Zielinski B, et al. Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells. Exp Neurol 1991;113:322-9
   PubMed Web of Science ®Google Scholar
• Legallais C, Doré DE. Bioartificial livers (BAL): Current technological aspects and future developments. J Membrane Sci 2001;181(181):81-54
   Web of Science ®Google Scholar
• Hortelano G, Xu N, Vandenberg A, et al. Persistent delivery of factor IX in mice: gene therapy for hemophilia using implantable microcapsules. Hum Gene Ther 1999;10:1281-8
   PubMed Web of Science ®Google Scholar
• Cheng WT, Chen BC, Chiou ST, Chen CM. Use of nonautologous microencapsulated fibroblasts in growth hormone gene therapy to improve growth of midget swine. Hum Gene Ther 1998;9:1995-2003
   PubMed Web of Science ®Google Scholar
• Lim F, Sun AM. Microencapsulated islets as bioartificial endocrine pancreas. Science (New York, NY) 1980;210(4472):908-10
   Web of Science ®Google Scholar
• Calafiore R, Basta G. Clinical application of microencapsulated islets: Actual prospectives on progress and challenges. Adv Drug Deliv Rev 2013. [ Epub ahead of print].
   Google Scholar
• Rabanel JM, Banquy X, Zouaoui H, et al. Progress technology in microencapsulation methods for cell therapy. Biotechnol Prog 2009;25(4):946-63
   PubMed Web of Science ®Google Scholar
• Paredes Juarez GA, Spasojevic M, Faas MM, de Vos P. Immunological and technical considerations in application of alginate-based microencapsulation systems. Front Bioeng Biotechnol 2014;2:26
   PubMedGoogle Scholar
• Rokstad AM, Lacik I, de Vos P, Strand BL. Advances in biocompatibility and physico-chemical characterization of microspheres for cell encapsulation. Adv Drug Deliv Rev 2014 Apr;67-68:111-30.
   Google Scholar
• Cantarelli E, Piemonti L. Alternative transplantation sites for pancreatic islet grafts. Curr Diab Rep 2011;11(5):364-74
   PubMed Web of Science ®Google Scholar
• Schweicher J, Nyitray C, Desai TA. Membranes to achieve immunoprotection of transplanted islets. Front Biosci (Landmark Ed) 2014;19:49-76
   PubMed Web of Science ®Google Scholar
• Colton CK. Implantable biohybrid artificial organs. Cell Transplant 1995;4(4):415-36
   PubMed Web of Science ®Google Scholar
• Li RH. Materials for immunoisolated cell transplantation. Adv Drug Deliv Rev 1998;33(1-2):87-109
   PubMed Web of Science ®Google Scholar
• Wang RN, Rosenberg L. Maintenance of beta-cell function and survival following islet isolation requires re-establishment of the islet-matrix relationship. J Endocrinol 1999;163(2):181-90
   PubMed Web of Science ®Google Scholar
• Carlsson PO, Palm F, Andersson A, Liss P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 2001;50(3):489-95
   PubMed Web of Science ®Google Scholar
• Strand BL, Mörch YA, Skjak-Bræk G. Alginate as immobilization matrix for cells. Minerva Biotecnologica 2001;12:223-33
   Web of Science ®Google Scholar
• Draget KI, Skjak-Braek G, Smidsrod O. Alginate based new materials. Int J Biol Macromol 1997;21(1-2):47-55
   PubMed Web of Science ®Google Scholar
• Soon-Shiong P, Desai NP, Sanford PA, et al. Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release. Patent PCT/US92/09364 World International Property Organization 1993;1-52
   Google Scholar
• Mazaheri R, Atkison P, Stiller C, et al. Transplantation of encapsulated allogeneic islets into diabetic BB/W rats. Effects of immunosuppression. Transplantation 1991;51(4):750-4
   PubMed Web of Science ®Google Scholar
• Duvivier-Kali VF, Omer A, Parent RJ, et al. Complete protection of islets against allorejection and autoimmunity by a simple barium-alginate membrane. Diabetes 2001;50(8):1698-705
   PubMed Web of Science ®Google Scholar
• Omer A, Duvivier-Kali V, Fernandes J, et al. Long-term normoglycemia in rats receiving transplants with encapsulated islets. Transplantation 2005;79(1):52-8
   PubMed Web of Science ®Google Scholar
• Wang T, Adcock J, Kuhtreiber W, et al. Successful allotransplantation of encapsulated islets in pancreatectomized canines for diabetic management without the use of immunosuppression. Transplantation 2008;85(3):331-7
   PubMed Web of Science ®Google Scholar
• Lanza RP, Jackson R, Sullivan A, et al. Xenotransplantation of cells using biodegradable microcapsules. Transplantation 1999;67(8):1105-11
   PubMed Web of Science ®Google Scholar
• Lum ZP, Krestow M, Tai IT, et al. Xenografts of rat islets into diabetic mice. An evaluation of new smaller capsules. Transplantation 1992;53(6):1180-3
   PubMed Web of Science ®Google Scholar
• Sun Y, Ma X, Zhou D, et al. Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J Clin Invest 1996;98(6):1417-22
   PubMed Web of Science ®Google Scholar
• Soon-Shiong P, Heintz RE, Merideth N, et al. Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation. Lancet 1994;343(8903):950-1
   PubMed Web of Science ®Google Scholar
• Calafiore R, Basta G, Luca G, et al. Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with type 1 diabetes: first two cases. Diabetes Care 2006;29(1):137-8
   PubMed Web of Science ®Google Scholar
• Bracho-Blanchet AC, Ramírez-González B, López-Santos MG, et al. Long-term follow-up of patients with type 1 diabetes trans- planted with neonatal pig islets. Clin Exp Immunol 2010;62:537-42
   Google Scholar
• Gala-Lopez B, Pepper AR, Shapiro JAM. Biologic agents in islet transplantation. Curr Diab Rep 2013;13(5):713-22
   PubMed Web of Science ®Google Scholar
• Jacobs-Tulleneers-Thevissen D, Chintinne M, Ling Z, et al. Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient. Diabetologia 2013;56(7):1605-14
   PubMed Web of Science ®Google Scholar
• Opara EC, McQuilling JP, Farney AC. Microencapsulation of pancreatic islets for use in a bioartificial pancreas. Methods Mol Biol 2013;1001:261-6
   PubMedGoogle Scholar
• Dufrane D, Gianello P. Macro- or microencapsulation of pig islets to cure type 1 diabetes. World J Gastroenterol 2012;18(47):6885-93
   PubMed Web of Science ®Google Scholar
• Santos E, Pedraz JL, Hernandez RM, Orive G. Therapeutic cell encapsulation: ten steps towards clinical translation. J Control Release 2013;170(1):1-14
   PubMed Web of Science ®Google Scholar
• Cruise GM, Hegre OD, Scharp DS, Hubbell JA. A sensitivity study of the key parameters in the interfacial photopolymerization of poly(ethylene glycol) diacrylate upon porcine islets. Biotechnol Bioeng 1998;57(6):655-65
   PubMed Web of Science ®Google Scholar
• Cruise GM, Scharp DS, Hubbell JA. Characterization of permeability and network structure of interfacially photopolymerized poly(ethylene glycol) diacrylate hydrogels. Biomaterials 1998;19(14):1287-94
   PubMed Web of Science ®Google Scholar
• Hill RS, Cruise GM, Hager SR, et al. Immunoisolation of adult porcine islets for the treatment of diabetes mellitus. The use of photopolymerizable polyethylene glycol in the conformal coating of mass-isolated porcine islets. Ann N Y Acad Sci 1997;831:332-43
   PubMed Web of Science ®Google Scholar
• Tomei AA, Manzoli V, Fraker CA, et al. Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci U S A 2014 Jun 30;111(29):10514-19.
   Google Scholar
• Bryant SJ, Bender RJ, Durand KL, Anseth KS. Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production. Biotechnol Bioeng 2004;86(7):747-55
   PubMed Web of Science ®Google Scholar
• Burdick JA, Anseth KS. Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 2002;23(22):4315-23
   PubMed Web of Science ®Google Scholar
• Nuttelman CR, Tripodi MC, Anseth KS. In vitro osteogenic differentiation of human mesenchymal stem cells photoencapsulated in PEG hydrogels. J Biomed Mat Res Part A 2004;68(4):773-82
   PubMed Web of Science ®Google Scholar
• Tomei AA, Manzoli V, Fraker CA, et al. Device design and materials optimization of conformal coating for islets of Langerhans. Proc Natl Acad Sci U S A 2014;111(29):10514-19
   PubMed Web of Science ®Google Scholar
• Lee DY, Park SJ, Nam JH, Byun Y. A new strategy toward improving immunoprotection in cell therapy for diabetes mellitus: long-functioning PEGylated islets in vivo. Tissue Eng 2006;12(3):615-23
   PubMedGoogle Scholar
• Gattas-Asfura KM, Stabler CL. Bioorthogonal layer-by-layer encapsulation of pancreatic islets via hyperbranched polymers. ACS Appl Mater Interfaces 2013;5(20):9964-74
   PubMed Web of Science ®Google Scholar
• Rengifo HR, Giraldo JA, Labrada I, Stabler CL. Long-term survival of allograft murine islets coated via covalently stabilized polymers. Adv Healthc Mater 2014;3(7):1061-70. PEGylation nanocoatings
   Web of Science ®Google Scholar
• Stendahl JC, Kaufman DB, Stupp SI. Extracellular matrix in pancreatic islets: relevance to scaffold design and transplantation. Cell Transplant 2009;18(1):1-12
   PubMed Web of Science ®Google Scholar
• Sawhney AS, Pathak CP, Hubbell JA. Interfacial photopolymerization of poly(ethylene glycol)-based hydrogels upon alginate-poly(l-lysine) microcapsules for enhanced biocompatibility. Biomaterials 1993;14(13):1008-16
   PubMed Web of Science ®Google Scholar
• Chen P, Chu IU, Shiao SY, Fu J. Microencapsulation of islets in PEG-amine modified alginate–poly(l-lysine)–alginate microcapsules for constructing bioartificial pancreas. Ferment Bioeng 1998;86:185-90
   Google Scholar
• O’Shea GM, Sun AM. Encapsulation of rat islets of langerhans prolongs xenograft survival in diabetic mice Diabetes. 1986;35:943-6
   Google Scholar
• Mikos AG, McIntire LV, Anderson JM, Babensee JE. Host response to tissue engineered devices. Adv Drug Deliv Rev 1998;33(1-2):111-39
   PubMed Web of Science ®Google Scholar
• Rihova B. Immunocompatibility and biocompatibility of cell delivery systems. Adv Drug Deliv Rev 2000;42(1-2):65-80
   PubMed Web of Science ®Google Scholar
• Narang AS, Mahato RI. Biological and biomaterial approaches for improved islet transplantation. Pharmacol Rev 2006;58(2):194-243
   PubMed Web of Science ®Google Scholar
• de Vos P, Faas MM, Strand B, Calafiore R. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials 2006;27(32):5603-17
   PubMed Web of Science ®Google Scholar
• De Vos P, De Haan BJ, Wolters GH, et al. Improved biocompatibility but limited graft survival after purification of alginate for microencapsulation of pancreatic islets. Diabetologia 1997;40(3):262-70
   PubMed Web of Science ®Google Scholar
• Charissoux JL, Najid A, Moreau JC, et al. Development of in vitro biocompatibility assays for surgical material. Clin Orthop Relat Res 1996 May(326):259-69
   PubMed Web of Science ®Google Scholar
• Lloyd AW, Dropcova S, Faragher RG, et al. The development of in vitro biocompatibility tests for the evaluation of intraocular biomaterials. J Mater science Mater Med 1999 Oct-Nov;10:10/11):6-7
   Web of Science ®Google Scholar
• Brissova M, Petro M, Lacik I, et al. Evaluation of microcapsule permeability via inverse size exclusion chromatography. Anal Biochem 1996;242(1):104-11
   PubMed Web of Science ®Google Scholar
• Lacik I. Polymer chemistry in diabetes treatment by encapsulated islets of Langerhans: review to 2006. Aust J Chem 2006;59(8):508-24
   Web of Science ®Google Scholar
• Carlsson PO, Palm F, Andersson A, Liss P. Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule. Transplantation 2000;69(5):761-6
   PubMed Web of Science ®Google Scholar
• Gaserod O, Smidsrod O, Skjak-Braek G. Microcapsules of alginate-chitosan--I. A quantitative study of the interaction between alginate and chitosan. Biomaterials 1998;19(20):1815-25
   PubMed Web of Science ®Google Scholar
• Thu B, Bruheim P, Espevik T, et al. Alginate polycation microcapsules. II. Some functional properties. Biomaterials 1996;17(11):1069-79
   PubMed Web of Science ®Google Scholar
• Blasi P, Giovagnoli S, Schoubben A, et al. Preparation and in vitro and in vivo characterization of composite microcapsules for cell encapsulation. Int J Pharm 2006;324(1):27-36
   PubMed Web of Science ®Google Scholar
• Lacik I, Brissova M, Anilkumar AV, et al. New capsule with tailored properties for the encapsulation of living cells. J Biomed Mater Res 1998;39(1):52-60
   PubMed Web of Science ®Google Scholar
• Orive G, Hernandez RM, Gascon AR, et al. Survival of different cell lines in alginate-agarose microcapsules. Eur J Pharm Sci 2003;18(1):23-30
   PubMed Web of Science ®Google Scholar
• de Vos P, Spasojevic M, de Haan BJ, Faas MM. The association between in vivo physicochemical changes and inflammatory responses against alginate based microcapsules. Biomaterials 2012;33(22):5552-9
   PubMed Web of Science ®Google Scholar
• Soon-Shiong P FE, Nelson R, Heintz R, et al. Long-term reversal of diabetes in the large animal model by encapsulated islet transplantation. Transplant Proc 1992;24(6):2946-7
   PubMed Web of Science ®Google Scholar
• Schmidt JJ, Rowley J, Kong HJ. Hydrogels used for cell-based drug delivery. J Biomed Mater Res Part A 2008;87(4):1113-22
   PubMed Web of Science ®Google Scholar
• Morch YA, Donati I, Strand BL, Skjak-Braek G. Effect of Ca2+, Ba2+, and Sr2+ on alginate microbeads. Biomacromolecules 2006;7(5):1471-80
   PubMed Web of Science ®Google Scholar
• Darrabie MD, Kendall WF, Opara EC. Effect of alginate composition and gelling cation on microbead swelling. J Microencapsul 2006;23(6):613-21
   PubMed Web of Science ®Google Scholar
• O’Sullivan ES, Vegas A, Anderson DG, Weir GC. Islets transplanted in immunoisolation devices: a review of the progress and the challenges that remain. Endocr Rev 2011;32(6):827-44
   PubMed Web of Science ®Google Scholar
• de Vos P, Bucko M, Gemeiner P, et al. Multiscale requirements for bioencapsulation in medicine and biotechnology. Biomaterials 2009;30(13):2559-70
   PubMed Web of Science ®Google Scholar
• Thanos CG, Calafiore R, Basta G, et al. Formulating the alginate-polyornithine biocapsule for prolonged stability: evaluation of composition and manufacturing technique. J Biomed Mater Res Part A 2007;83(1):216-24
   PubMed Web of Science ®Google Scholar
• Williams SJ, Huang HH, Kover K, et al. Reduction of diffusion barriers in isolated rat islets improves survival, but not insulin secretion or transplantation outcome. Organogenesis 2010;6(2):115-24
   PubMed Web of Science ®Google Scholar
• Buchwald P. FEM-based oxygen consumption and cell viability models for avascular pancreatic islets. Theor Biol Med Model 2009;6:5
   PubMed Web of Science ®Google Scholar
• Buchwald P. A local glucose-and oxygen concentration-based insulin secretion model for pancreatic islets. Theor Biol Med Model 2011;8:20
   PubMed Web of Science ®Google Scholar
• Elliott RB, Escobar L, Tan PL, et al. Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xenotransplantation 2007;14(2):157-61
   PubMed Web of Science ®Google Scholar
• Tuch BE, Keogh GW, Williams LJ, et al. Safety and viability of microencapsulated human islets transplanted into diabetic humans. Diabetes Care 2009;32(10):1887-9
   PubMed Web of Science ®Google Scholar
• De Vos P, Vegter D, De Haan BJ, et al. Kinetics of intraperitoneally infused insulin in rats. Functional implications for the bioartificial pancreas. Diabetes 1996;45(8):1102-7
   PubMed Web of Science ®Google Scholar
• Colton CK, Avgoustiniatos ES. Bioengineering in development of the hybrid artificial pancreas. J Biomech Eng 1991;113(2):152-70
   PubMed Web of Science ®Google Scholar
• de Vos P, Vegter D, Strubbe JH, et al. Impaired glucose tolerance in recipients of an intraperitoneally implanted microencapsulated islet allograft is caused by the slow diffusion of insulin through the peritoneal membrane. Transplant Proc 1997;29(1-2):756-7
   PubMed Web of Science ®Google Scholar
• Bennet W, Groth CG, Larsson R, et al. Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes. Ups J Med Sci 2000;105(2):125-33
   PubMed Web of Science ®Google Scholar
• Gill RG, Bishop NH. Clinical islet transplantation: where immunity and metabolism intersect?. Curr Opin Endocrinol Diabetes Obes 2012;19(4):249-54
   PubMed Web of Science ®Google Scholar
• Berman DM, O’Neil JJ, Coffey LC, et al. Long-term survival of nonhuman primate islets implanted in an omental pouch on a biodegradable scaffold. Am J Transplant 2009;9(1):91-104
   PubMed Web of Science ®Google Scholar
• Najjar M, Manzoli V, Villa C, et al. Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice. Biotechnol Bioeng 2015 Mar 18;10.1002/bit.25589. [Epub ahead of print]
   PubMed Web of Science ®Google Scholar
• Echeverri GJ, McGrath K, Bottino R, et al. Endoscopic gastric submucosal transplantation of islets (ENDO-STI): technique and initial results in diabetic pigs. Am J Transplant 2009;9(11):2485-96
   PubMed Web of Science ®Google Scholar
• Jansson L, Carlsson PO. Graft vascular function after transplantation of pancreatic islets. Diabetologia 2002;45(6):749-63
   PubMed Web of Science ®Google Scholar
• Brissova M, Powers AC. Revascularization of transplanted islets: can it be improved? Diabetes 2008;57(9):2269-71
   PubMed Web of Science ®Google Scholar
• Narang AS, Cheng K, Henry J, et al. Vascular endothelial growth factor gene delivery for revascularization in transplanted human islets. Pharm Res 2004;21(1):15-25
   PubMed Web of Science ®Google Scholar
• Stendahl JC, Wang LJ, Chow LW, et al. Growth factor delivery from self-assembling nanofibers to facilitate islet transplantation. Transplantation 2008;86(3):478-81
   PubMed Web of Science ®Google Scholar
• Pedraza E, Coronel MM, Fraker CA, et al. Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials. Proc Natl Acad Sci U S A 2012;109(11):4245-50
   PubMed Web of Science ®Google Scholar
• Marzorati S, Bocca N, Molano RD, et al. Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device. Transplant Proc 2009;41(1):352-3
   PubMed Web of Science ®Google Scholar
• Beattie GM, Montgomery AM, Lopez AD, et al. A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes 2002;51(12):3435-9
   PubMed Web of Science ®Google Scholar
• Orlando G, Gianello P, Salvatori M, et al. Cell replacement strategies aimed at reconstitution of the beta-cell compartment in type 1 diabetes. Diabetes 2014;63(5):1433-44
   PubMed Web of Science ®Google Scholar
• Abdelalim EM, Emara MM. Advances and challenges in the differentiation of pluripotent stem cells into pancreatic beta cells. World J Stem Cells 2015;7(1):174-81
   PubMed Web of Science ®Google Scholar
• Lysy PA, Weir GC, Bonner-Weir S. Concise review: pancreas regeneration: recent advances and perspectives. Stem Cells Transl Med 2012;1(2):150-9
   PubMed Web of Science ®Google Scholar
• D’Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24(11):1392-401
   PubMed Web of Science ®Google Scholar
• Kroon E, Martinson LA, Kadoya K, et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 2008;26(4):443-52
   PubMed Web of Science ®Google Scholar
• Pagliuca FW, Millman JR, Gurtler M, et al. Generation of functional human pancreatic beta cells in vitro. Cell 2014;159(2):428-39
   PubMed Web of Science ®Google Scholar
• Rezania A, Bruin JE, Arora P, et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat Biotechnol 2014;32(11):1121-33
   PubMed Web of Science ®Google Scholar
• Yang HK, Yoon KH. Current status of encapsulated islet transplantation. J Diabetes Complications 2015; [Epub ahead of print]
   Google Scholar
• Bellin MD, Barton FB, Heitman A, et al. Potent induction immunotherapy promotes long-term insulin independence after islet transplantation in type 1 diabetes. Am J Transplant 2012;12(6):1576-83
   PubMed Web of Science ®Google Scholar
• Guleria I, Gubbels Bupp M, Dada S, et al. Mechanisms of PDL1-mediated regulation of autoimmune diabetes. Clin Immunol (Orlando, Fla) 2007;125(1):16-25
   PubMed Web of Science ®Google Scholar
• Pileggi A, Xu X, Tan J, Ricordi C. Mesenchymal stromal (stem) cells to improve solid organ transplant outcome: lessons from the initial clinical trials. Curr Opin Organ Transplant 2013;18(6):672-81
   PubMed Web of Science ®Google Scholar
• Francese R, Fiorina P. Immunological and regenerative properties of cord blood stem cells. Clin Immunol (Orlando, Fla) 2010;136(3):309-22
   PubMed Web of Science ®Google Scholar
• Fiorina P, Jurewicz M, Vergani A, et al. Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1. J Immunol (Baltimore, Md : 1950) 2011 Jan 1;186(1):121-31
   PubMed Web of Science ®Google Scholar
• Korpos E, Kadri N, Kappelhoff R, et al. The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. Diabetes 2013;62(2):531-42
   PubMed Web of Science ®Google Scholar
• Verhoef JJ, Carpenter JF, Anchordoquy TJ, Schellekens H. Potential induction of anti-PEG antibodies and complement activation toward PEGylated therapeutics. Drug Discov Today 2014 Sep 7;19(12):1945-52
   Google Scholar
• Riolobos L, Hirata RK, Turtle CJ, et al. HLA engineering of human pluripotent stem cells. Mol Ther 2013;21(6):1232-41
   PubMed Web of Science ®Google Scholar