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Reviews

Stem cells therapy for ALS

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Pages 187-199 | Received 16 Sep 2015, Accepted 02 Nov 2015, Published online: 09 Jan 2016

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•• The demonstration that glial cells have a primary role in the onset and progression of the disease in ALS animal model

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• This study demonstrated that focal astrocyte transplantation protect MNs in animal models and delays respiratory failure

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• A very interesting review that shows the potential therapeutic effects of MSCs in neurodegenerative diseases

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• This study represents the first report of the therapeutic effects of MSCs in ALS animal model

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• This is a comprehensive review on clinical trials with stem cells in ALS

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• This is the first reports of intraparenchymal stem cell transplantation in ALS patients

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