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Miscellaneous

Development of an orphanin FQ (OFQ) receptor antagonist for the treatment of chronic pain

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Pages 49-51 | Published online: 25 Feb 2005

Reference

  • REINSCHEID et al.: Orphanin FQ: a neuropeptide that activates an opioidlike G-protein-coupled receptor. Science (1995) 270:792-794.
  • MOGIL et al.: Opioid and nonopioid swim stress-induced analgesia: a parametric analysis in mice. Physiol. Behav. (1996) 59:123-132.
  • MOGIL et al.: Orphanin FQ is a functional anti-opioid peptide. Neuroscience (1996) 75:333-337.
  • TIAN A et al.: Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia. Neuroreport 8:497–500.
  • TIAN A et al.: Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of rats. Br. .1 Pharmacol. 120:676–680.

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