Exploring the safety of chemotherapy for treating breast cancer during pregnancy

Bibliography

• Cancer of the Breast - SEER stat fact sheets. Available from: http://seer.cancer.gov/statfacts/html/breast.html [Last accessed 9 June 2015]
   Google Scholar
• Smith LH, Dalrymple JL, Leiserowitz GS, et al. Obstetrical deliveries associated with maternal malignancy in California, 1992 through 1997. Am J Obstet Gynecol 2001;184(7):1504-12. discussion 1512–3
   PubMed Web of Science ®Google Scholar
• Smith LH, Danielsen B, Allen ME, Cress R. Cancer associated with obstetric delivery: results of linkage with the California cancer registry. Am J Obstet Gynecol 2003;189(4):1128-35
   PubMed Web of Science ®Google Scholar
• Abenhaim HA, Azoulay L, Holcroft CA, et al. Incidence, risk factors, and obstetrical outcomes of women with breast cancer in pregnancy. Breast J 2012;18(6):564-8
   PubMed Web of Science ®Google Scholar
• Johnson JA, Tough S; Society of Obstetricians and Gynaecologists of Canada. Delayed child-bearing. J Obstet Gynaecol Can 2012;34(1):80-93
   PubMedGoogle Scholar
• Merlo DF, Ceppi M, Filiberti R, et al. Breast cancer incidence trends in European women aged 20-39 years at diagnosis. Breast Cancer Res Treat 2012;134(1):363-70
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Partridge AH. Biology of breast cancer in young women. Breast Cancer Res 2014;16(4):427
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Michiels S, Bedard PL, et al. Elucidating prognosis and biology of breast cancer arising in young women using gene expression profiling. Clin Cancer Res 2012;18(5):1341-51
   PubMed Web of Science ®Google Scholar
• Schedin P. Pregnancy-associated breast cancer and metastasis. Nat Rev Cancer 2006;6(4):281-91
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Botteri E, Renne G, et al. The biological features and prognosis of breast cancer diagnosed during pregnancy: a case-control study. Acta Oncol 2012;51(5):653-61
   PubMed Web of Science ®Google Scholar
• Litton JK, Warneke CL, Hahn KM, et al. Case control study of women treated with chemotherapy for breast cancer during pregnancy as compared with nonpregnant patients with breast cancer. Oncologist 2013;18(4):369-76
   PubMed Web of Science ®Google Scholar
• Amant F, von Minckwitz G, Han SN, et al. Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study. J Clin Oncol 2013;31(20):2532-9
   PubMed Web of Science ®Google Scholar
• Murphy CG, Mallam D, Stein S, et al. Current or recent pregnancy is associated with adverse pathologic features but not impaired survival in early breast cancer. Cancer 2012;118(13):3254-9
   PubMed Web of Science ®Google Scholar
• Genin A-S, Lesieur B, Gligorov J, et al. Pregnancy-associated breast cancers: do they differ from other breast cancers in young women? Breast 2012;21(4):550-5
   PubMed Web of Science ®Google Scholar
• Madaras L, Kovács KA, Szász AM, et al. Clinicopathological features and prognosis of pregnancy associated breast cancer - a matched case control study. Pathol Oncol Res 2014;20(3):581-90
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Brohée S, Peccatori FA, et al. Biology of breast cancer during pregnancy using genomic profiling. Endocr Relat Cancer 2014;21(4):545-54
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Peccatori FA, Brohée S, et al. RANK-ligand (RANKL) expression in young breast cancer patients and during pregnancy. Breast Cancer Res 2015;17(1):24
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Vingiani A, Peccatori F, et al. Tumour infiltrating lymphocytes (TILs) in breast cancer during pregnancy. Breast 2015;24(3):290-3
   PubMed Web of Science ®Google Scholar
• Amant F, Loibl S, Neven P, Van Calsteren K. Breast cancer in pregnancy. Lancet 2012;379(9815):570-9
   PubMed Web of Science ®Google Scholar
• Peccatori FA, Azim HAJr, Orecchia R, et al. Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2013;24(Suppl 6):vi160-70
   PubMed Web of Science ®Google Scholar
• Pentheroudakis G, Pavlidis N. Cancer and pregnancy: poena magna, not anymore. Eur J Cancer 2006;42(2):126-40
   PubMed Web of Science ®Google Scholar
• Gentilini O, Cremonesi M, Trifirò G, et al. Safety of sentinel node biopsy in pregnant patients with breast cancer. Ann Oncol 2004;15(9):1348-51
   PubMed Web of Science ®Google Scholar
• Gentilini O, Cremonesi M, Toesca A, et al. Sentinel lymph node biopsy in pregnant patients with breast cancer. Eur J Nucl Med Mol Imaging 2010;37(1):78-83
   PubMed Web of Science ®Google Scholar
• Kal HB, Struikmans H. Radiotherapy during pregnancy: fact and fiction. Lancet Oncol 2005;6(5):328-33
   PubMed Web of Science ®Google Scholar
• Lambertini M, Peccatori FA, Azim HA. Targeted agents for cancer treatment during pregnancy. Cancer Treat Rev 2015;41(4):301-9
   PubMed Web of Science ®Google Scholar
• CFR. Code of federal regulations title 21. Available from: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.57 [Last accessed 9 June 2015]
   Google Scholar
• Loibl S, von Minckwitz G, Gwyn K, et al. Breast carcinoma during pregnancy. International recommendations from an expert meeting. Cancer 2006;106(2):237-46
   PubMed Web of Science ®Google Scholar
• National Toxicology Program. NTP Monograph: Developmental effects and pregnancy outcomes associated with cancer chemotherapy use during pregnancy. NTP Monogr 2013(2):i-214
   PubMedGoogle Scholar
• Correa A, Cragan JD, Kucik JE, et al. Reporting birth defects surveillance data 1968-2003. Birt Defects Res A Clin Mol Teratol 2007;79(2):65-186
   PubMedGoogle Scholar
• Martin JA, Hamilton BE, Ventura SJ, et al. Births: final data for 2009. Natl Vital Stat Rep 2011;60(1):1-70
   PubMedGoogle Scholar
• Brenner B, Avivi I, Lishner M. Haematological cancers in pregnancy. Lancet 2012;379(9815):580-7
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Peccatori FA, Pavlidis N. Treatment of the pregnant mother with cancer: a systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part I: Solid tumors. Cancer Treat Rev 2010;36(2):101-9
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Pavlidis N, Peccatori FA. Treatment of the pregnant mother with cancer: a systematic review on the use of cytotoxic, endocrine, targeted agents and immunotherapy during pregnancy. Part II: Hematological tumors. Cancer Treat Rev 2010;36(2):110-21
   PubMed Web of Science ®Google Scholar
• Azim HAJr, Del Mastro L, Scarfone G, Peccatori FA. Treatment of breast cancer during pregnancy: regimen selection, pregnancy monitoring and more. Breast 2011;20(1):1-6
   PubMed Web of Science ®Google Scholar
• Van Calsteren K, Heyns L, De Smet F, et al. Cancer during pregnancy: an analysis of 215 patients emphasizing the obstetrical and the neonatal outcomes. J Clin Oncol 2010;28(4):683-9
   PubMed Web of Science ®Google Scholar
• Cardonick E, Dougherty R, Grana G, et al. Breast cancer during pregnancy: maternal and fetal outcomes. Cancer J 2010;16(1):76-82
   PubMed Web of Science ®Google Scholar
• Loibl S, Han SN, von Minckwitz G, et al. Treatment of breast cancer during pregnancy: an observational study. Lancet Oncol 2012;13(9):887-96
   PubMed Web of Science ®Google Scholar
• Amant F, Van Calsteren K, Halaska MJ, et al. Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study. Lancet Oncol 2012;13(3):256-64
   PubMed Web of Science ®Google Scholar
• Boike GM, Deppe G, Young JD, et al. Chemotherapy in a pregnant rat model. 2.5-fluorouracil: nonlinear kinetics and placental transfer. Gynecol Oncol 1989;34(2):191-4
   PubMed Web of Science ®Google Scholar
• Stephens JD, Golbus MS, Miller TR, et al. Multiple congenital anomalies in a fetus exposed to 5-fluorouracil during the first trimester. Am J Obstet Gynecol 1980;137(6):747-9
   PubMed Web of Science ®Google Scholar
• Schleuning M, Clemm C. Chromosomal aberrations in a newborn whose mother received cytotoxic treatment during pregnancy. N Engl J Med 1987;317(26):1666-7
   PubMed Web of Science ®Google Scholar
• Vaux KK, Kahole NCO, Jones KL. Cyclophosphamide, methotrexate, and cytarabine embropathy: is apoptosis the common pathway? Birt Defects Res A Clin Mol Teratol 2003;67(6):403-8
   PubMed Web of Science ®Google Scholar
• Hyoun SC, Običan SG, Scialli AR. Teratogen update: methotrexate. Birt Defects Res A Clin Mol Teratol 2012;94(4):187-207
   PubMed Web of Science ®Google Scholar
• Kulier R, Kapp N, Gülmezoglu AM, et al. Medical methods for first trimester abortion. Cochrane Database Syst Rev 2011(11):CD002855
   Google Scholar
• D’Incalci M, Sessa C, Colombo N, et al. Transplacental passage of cyclophosphamide. Cancer Treat Rep 1982;66(8):1681-2
   PubMedGoogle Scholar
• Van Calsteren K, Verbesselt R, Beijnen J, et al. Transplacental transfer of anthracyclines, vinblastine, and 4-hydroxy-cyclophosphamide in a baboon model. Gynecol Oncol 2010;119(3):594-600
   PubMed Web of Science ®Google Scholar
• D’ Incalci M, Broggini M, Buscaglia M, Pardi G. Transplacental passage of doxorubicin. Lancet 1983;1(8314-5):75
   PubMed Web of Science ®Google Scholar
• Karp GI, von Oeyen P, Valone F, et al. Doxorubicin in pregnancy: possible transplacental passage. Cancer Treat Rep 1983;67(9):773-7
   PubMedGoogle Scholar
• Van Calsteren K, Verbesselt R, Van Bree R, et al. Substantial variation in transplacental transfer of chemotherapeutic agents in a mouse model. Reprod Sci 2011;18(1):57-63
   PubMed Web of Science ®Google Scholar
• Gziri MM, Pokreisz P, De Vos R, et al. Fetal rat hearts do not display acute cardiotoxicity in response to maternal Doxorubicin treatment. J Pharmacol Exp Ther 2013;346(3):362-9
   PubMed Web of Science ®Google Scholar
• Gziri MM, Debiève F, DE Catte L, et al. Chemotherapy during pregnancy: effect of anthracyclines on fetal and maternal cardiac function. Acta Obstet Gynecol 2012;91(12):1465-8
   PubMed Web of Science ®Google Scholar
• Calsteren KV, Verbesselt R, Devlieger R, et al. Transplacental transfer of paclitaxel, docetaxel, carboplatin, and trastuzumab in a baboon model. Int J Gynecol 2010;20(9):1456-64
   Google Scholar
• Mir O, Berveiller P, Ropert S, et al. Emerging therapeutic options for breast cancer chemotherapy during pregnancy. Ann Oncol 2008;19(4):607-13
   PubMed Web of Science ®Google Scholar
• Smit JW, Huisman MT, van Tellingen O, et al. Absence or pharmacological blocking of placental P-glycoprotein profoundly increases fetal drug exposure. J Clin Invest 1999;104(10):1441-7
   PubMed Web of Science ®Google Scholar
• Scialli AR, DeSesso JM, Rahman A, et al. Embryotoxicity of free and liposome-encapsulated taxol in the chick. Pharmacology 1995;51(3):145-51
   PubMed Web of Science ®Google Scholar
• Scialli AR, Waterhouse TB, Desesso JM, et al. Protective effect of liposome encapsulation on paclitaxel developmental toxicity in the rat. Teratology 1997;56(5):305-10
   PubMedGoogle Scholar
• Cardonick E, Usmani A, Ghaffar S. Perinatal outcomes of a pregnancy complicated by cancer, including neonatal follow-up after in utero exposure to chemotherapy: results of an international registry. Am J Clin Oncol 2010;33(3):221-8
   PubMed Web of Science ®Google Scholar
• Sekar R, Stone PR. Trastuzumab use for metastatic breast cancer in pregnancy. Obstet Gynecol 2007;110(2 Pt 2):507-10
   PubMed Web of Science ®Google Scholar
• Gottschalk I, Berg C, Harbeck N, et al. Fetal renal insufficiency following trastuzumab treatment for breast cancer in pregnancy: case report und review of the current literature. Breast Care 2011;6(6):475-8
   PubMed Web of Science ®Google Scholar
• Massey Skatulla L, Loibl S, Schauf B, Müller T. Pre-eclampsia following chemotherapy for breast cancer during pregnancy: case report and review of the literature. Arch Gynecol Obstet 2012;286(1):89-92
   PubMed Web of Science ®Google Scholar
• Rouzier R, Werkoff G, Uzan C, et al. Pregnancy-associated breast cancer is as chemosensitive as non-pregnancy-associated breast cancer in the neoadjuvant setting. Ann Oncol 2011;22(7):1582-7
   PubMed Web of Science ®Google Scholar
• Giacalone PL, Laffargue F, Bénos P. Chemotherapy for breast carcinoma during pregnancy: A French national survey. Cancer 1999;86(11):2266-72
   PubMed Web of Science ®Google Scholar
• Ring AE, Smith IE, Jones A, et al. Chemotherapy for breast cancer during pregnancy: an 18-year experience from five London teaching hospitals. J Clin Oncol 2005;23(18):4192-7
   PubMed Web of Science ®Google Scholar
• Peccatori FA, Azim HAJr, Scarfone G, et al. Weekly epirubicin in the treatment of gestational breast cancer (GBC). Breast Cancer Res Treat 2009;115(3):591-4
   PubMed Web of Science ®Google Scholar
• García-Manero M, Royo MP, Espinos J, et al. Pregnancy associated breast cancer. Eur J Surg Oncol 2009;35(2):215-18
   PubMed Web of Science ®Google Scholar
• Murthy RK, Theriault RL, Barnett CM, et al. Outcomes of children exposed in utero to chemotherapy for breast cancer. Breast Cancer Res 2014;16(6):3414
   Web of Science ®Google Scholar
• Del Mastro L, De Placido S, Bruzzi P, et al. Fluorouracil and dose-dense chemotherapy in adjuvant treatment of patients with early-stage breast cancer: an open-label, 2 × 2 factorial, randomised phase 3 trial. Lancet 2015;385(9980):1863-72
   PubMed Web of Science ®Google Scholar
• Zagouri F, Sergentanis TN, Chrysikos D, et al. Taxanes for breast cancer during pregnancy: a systematic review. Clin Breast Cancer 2013;13(1):16-23
   PubMed Web of Science ®Google Scholar
• Bonilla L, Ben-Aharon I, Vidal L, et al. Dose-dense chemotherapy in nonmetastatic breast cancer: a systematic review and meta-analysis of randomized controlled trials. J Natl Cancer Inst 2010;102(24):1845-54
   PubMed Web of Science ®Google Scholar
• Cardonick E, Gilmandyar D, Somer RA. Maternal and neonatal outcomes of dose-dense chemotherapy for breast cancer in pregnancy. Obstet Gynecol 2012;120(6):1267-72
   PubMed Web of Science ®Google Scholar
• Meisel JL, Economy KE, Calvillo KZ, et al. Contemporary multidisciplinary treatment of pregnancy-associated breast cancer. SpringerPlus 2013;2(1):297
   Google Scholar
• Van Calsteren K, Verbesselt R, Ottevanger N, et al. Pharmacokinetics of chemotherapeutic agents in pregnancy: a preclinical and clinical study. Acta Obstet Gynecol 2010;89(10):1338-45
   PubMed Web of Science ®Google Scholar
• Van Hasselt JGC, van Calsteren K, Heyns L, et al. Optimizing anticancer drug treatment in pregnant cancer patients: pharmacokinetic analysis of gestation-induced changes for doxorubicin, epirubicin, docetaxel and paclitaxel. Ann Oncol 2014;25(10):2059-65
   PubMed Web of Science ®Google Scholar
• Krishna I, Lindsay M. Breast cancer in pregnancy. Obstet Gynecol 2013;40(3):559-71
   Web of Science ®Google Scholar
• Institute of Medicine (US) Committee on Understanding Premature Birth and Assuring Healthy Outcomes. Preterm birth: causes, consequences, and prevention. National Academies Press, US, Washington, DC; Available from: http://www.ncbi.nlm.nih.gov/books/NBK11362/ [Last accessed 9 June 2015]
   Google Scholar
• Abdel-Hady E-S, Hemida RA-H, Gamal A, et al. Cancer during pregnancy: perinatal outcome after in utero exposure to chemotherapy. Arch Gynecol Obstet 2012;286(2):283-6
   PubMed Web of Science ®Google Scholar
• Cardonick EH, Gringlas MB, Hunter K, Greenspan J. Development of children born to mothers with cancer during pregnancy: comparing in utero chemotherapy-exposed children with nonexposed controls. Am J Obstet Gynecol 2015;212(5):658.e1-8
   Google Scholar
• Partridge AH, Garber JE. Long-term outcomes of children exposed to antineoplastic agents in utero. Semin Oncol 2000;27(6):712-26
   PubMed Web of Science ®Google Scholar
• Gziri MM, Hui W, Amant F, et al. Myocardial function in children after fetal chemotherapy exposure. A tissue Doppler and myocardial deformation imaging study. Eur J Pediatr 2013;172(2):163-70
   PubMed Web of Science ®Google Scholar
• Amant F, Deckers S, Van Calsteren K, et al. Breast cancer in pregnancy: recommendations of an international consensus meeting. Eur J Cancer 2010;46(18):3158-68
   PubMed Web of Science ®Google Scholar