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Expert Opinion on Drug Safety Volume 15, 2016 - Issue 1
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Reviews

Safety of monoclonal antibodies and related therapeutic proteins for the treatment of neovascular macular degeneration: addressing outstanding issues

Focke ZiemssenCenter for Ophthalmology, Eberhard Karl University, D-72076Tuebingen, GermanyCorrespondence[email protected]
,
Bianka SobolewskaCenter for Ophthalmology, Eberhard Karl University, D-72076Tuebingen, Germany
,
Heidrun DeisslerDepartment of Ophthalmology, Univeristy of Ulm, D-89075Ulm, Germany
&
Helmut DeisslerHD/U Biomedical Services, 89079Ulm, Germany
Pages 75-87 | Published online: 11 Dec 2015

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•• The results of the comparative trial are supplmented by a literature review of adverse events in RCTs.

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••Though subject of discussion - this original paper gives evidence of the systemic interaction with serum proteins after intravitreous administration of anti-VEGF drugs.

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