Bibliography
- LIU B, LI S, HU J: Technological advances in high-throughput screening. Am. J. Pharmacogenomics (2004) 4:263–276.
- JAGER S, BRAND L, EGGELING C: New fluorescence techniques for highthroughput drug discovery. Curr. Pharm. Biotechnol. (2003) 4:463–476.
- MUEGGE I: Selection criteria for drug-like compounds. Med. Res. Rev. (2003) 23:302–321.
- LIPINSKI CA, LOMBARDO F, DOMINY BW, FEENEY PJ: Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. (2001) 46:3–26.
- YU LX, AMIDON GL: A compartmental absorption and transit model for estimating oral drug absorption. Int. J. Pharm. (1999) 186:119–125.
- WILLMANN S, SCHMITT W, KELDENICH J, LIPPERT J, DRESSMAN JB: A physiological model for the estimation of the fraction dose absorbed in humans. J. Med. Chem. (2004) 47:4022–4031.
- WILLMANN S, SCHMITT W, KELDENICH J, DRESSMAN JB: A physiologic model for simulating gastrointestinal flow and drug absorption in rats. Pharm. Res. (2003) 20:1766–1771.
- PARROTT N, LAVE T: Prediction of intestinal absorption: comparative assessment of Gastroplus and Idea. Eur. J. Pharm. Sci. (2002) 17:51–61.
- LOIDL-STAHLHOFEN A, HARTMANN T, SCHOTTNER M et al.: Multilamellar liposomes and solidsupported lipid membranes (TRANSIL): screening of lipid-water partitioning toward a high-throughput scale. Pharm. Res. (2001) 18:1782–1788.
- LOIDL-STAHLHOFEN A, ECKERT A, HARTMANN T, SCHOTTNER M: Solid-supported lipid membranes as a tool for determination of membrane affinity: high-throughput screening of a physicochemical parameter. J. Pharm. Sci. (2001) 90:599–606.
- POULIN P, THEIL FP: Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition. J. Pharm. Sci. (2002) 91:1358–1370.
- POULIN P, THEIL FP: Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution. J. Pharm. Sci. (2002) 91:129–156.
- POULIN P, SCHOENLEIN K, THEIL FP: Prediction of adipose tissue: plasma partition coefficients for structurally unrelated drugs. J. Pharm. Sci. (2001) 90:436–447.
- POULIN P, THEIL FP: A priori prediction of tissue: plasma partition coefficients of drugs to facilitate the use of physiologicallybased pharmacokinetic models in drug discovery. J. Pharm. Sci. (2000) 89:16–35.
- HÄRTER MW, KELDENICH J, SCHMITT W: In: Combinatorial Chemistry - A Practical Handbook, Part IV. NC Nicolau, R Hanko, W Hartwig (Eds), Wiley VCH, Weinheim, Germany (2002).
- VALKO K: Application of highperformance liquid chromatography based measurements of lipophilicity to model biological distribution. J. Chromatogr. A (2004) 1037:299–310.
- ZHU C, JIANG L, CHEN TM, HWANG KK: A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential. Eur. J. Med. Chem. (2002) 37:399–407.
- ROUSER G, NELSON J, FLEISCHER S, SIMON G: In: Biological Membranes, Vol 1: Physical Facts and Function. D Chapman (Ed.), Academic Press, London (1968).
- ZABELINSKII SA, BROVTSYNA NB, CHEBOTAREVA MA, GORBUNOVA OB, KRIVCHENKO AI: Comparative investigation of lipid and fatty acid composition of fish gills and mammalian lungs. A model of the membrane lipid component areas. Comp Biochem. Physiol B Biochem. Mol. Biol. (1995) 111:127–140.
- SEELIG A: A general pattern for substrate recognition by P-glycoprotein. Eur. J. Biochem. (1998) 251:252–261.
- SEELIG A: How does P-glycoprotein recognize its substrates? Int. J. Clin. Pharmacol. Ther. (1998) 36:50–54
Websites
- http://www.simulations-plus.com/products/ gastro_plus.html GastroPlus product information by Simulations Plus (2005).
- http://www.pk-sim.com PK-Sim product information by Bayer Technology Services (2005).
- http://www.pk-map.com PK-Map product information by Bayer Technology Services (2005).
- http://www.nimbus-biotechnology.com NIMBUS website (2005.)
- http://www.lionbioscience.com/solutions/ e20380/e20496/index_eng.html iDEA product information by Lion Bioscience (2005).
- http://www.acdlabs.com/
- http://www.syrres.com/default.htm
- http://ap-algorithms.com/adme_boxes.htm
- http://www.knowitall.com