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Drug Evaluations

Pharmacokinetic and pharmacodynamic evaluation of panitumumab in the treatment of colorectal cancer

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Bibliography

  • •=of importance, ••= of considerable importance
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•The only head-to-head Phase III study between Panitumumab and Cetuximab in the chemorefractory setting.

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•Landmark review paper in describing the scientific rationale behind the development of Panitumumab.

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•The largest phase I study examining varying schedules and doses of Panitumumab.

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•The first published phase I study on Panitumumab.

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•• Phase III study that led to approval of panitumumab in first-line setting

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